Gasse, P. et al. (2007) IL-1R1/MyD88 signaling and the inflammasome are essential in pulmonary inflammation and fibrosis in mice. J. Clin. Invest. 117:3786.
Recombinant Mouse IL-1 beta (Catalog # 401-ML)
Sample: Mouse
Application: In vivo
Mouse IL-1 beta DuoSet® ELISA Development Kit (Catalog # DY401)
Sample: Lung homogenate
Application: ELISA
Mouse KC DuoSet ELISA Development Kit (Catalog # DY453)
Sample: Lung homogenate
Application: ELISA
Mouse IL-6 DuoSet ELISA Development Kit (Catalog # DY406)
Sample: Lung homogenate
Application: ELISA
Mouse TARC DuoSet ELISA Development Kit (Catalog # DY529)
Sample: Lung homogenate
Application: ELISA
Mouse TIMP-1 DuoSet ELISA Development Kit (Catalog # DY980)
Sample: BALF and lung homogenate
Application: ELISA
Canine/Mouse/Porcine/Rat TGF-beta 1 Quantikine® ELISA Kit (Catalog # MB100B)
Sample: BALF
Application: ELISA
Mariathasan, S. et al. (2006) Cryopyrin activates the inflammasome in response to toxins and ATP. Nature 440:228.
Mouse IL-1 beta Polyclonal Antibody (Catalog # AF-401-NA)
Sample: Peritoneal and bone marrow macrophages
Application: Immunoprecipitation
Mouse TNF-alpha Quantikine ELISA Kit (Catalog # MTA00)
Sample: Peritoneal and bone marrow macrophages
Application: ELISA
Mouse IL-12 p40 (Allele-specific) Quantikine ELISA Kit (Catalog # M1240)
Sample: Peritoneal and bone marrow macrophages
Application: ELISA
Miller, L.S. et al. (2007) Inflammasome-mediated production of IL-1 beta is required for neutrophil recruitment against Staphylococcus aureus in vivo. J. Immunol. 179:6933.
Mouse IL-1 beta Polyclonal Antibody (Catalog # AF-401-NA)
Sample: Skin lesion homogenates
Application: Western blot
Mouse KC Quantikine ELISA Kit (Catalog # MKC00B)
Sample: Skin lesion homogenates
Application: ELISA
Mouse CXCL2/MIP2 Quantikine ELISA Kit (Catalog # MM200)
Sample: Skin lesion homogenates
Application: ELISA
Petrilli, V. et al. (2007) Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration. Cell Death Differ. 14:1583.
Mouse IL-1 beta Quantikine ELISA Kit (Catalog # MLB00B)
Sample: Mouse peritoneal macrophage supernates
Application: ELISA
Reiniger, N. et al. (2007) Resistance to Pseudomonas aeruginosa chronic lung infection requires cystic fibrosis transmembrane conductance regulator-modulated interleukin-1 (IL-1) release and signaling through the IL-1 receptor. Infect. Immun. 75:1598.
Human IL-1 beta Quantikine ELISA kit (Catalog # DLB50)
Sample: CFT1 human bronchial epithelial cell supernates
Application: ELISA
Westermann, D. et al. (2007) Cardioprotective and anti-inflammatory effects of interleukin converting enzyme inhibition in experimental diabetic cardiomyopathy. Diabetes 56:1834.
Rat IL-18 Affinity Purified Polyclonal Antibody (Catalog # AF821)
Sample: Heart
Application: Immunohistochemistry
Rat IL-1 beta Affinity Purified Polyclonal Antibody (Catalog # AF-501-NA)
Sample: Heart
Application: Immunohistochemistry
Rat TNF-alpha Affinity Purified Polyclonal Antibody (Catalog # AF-510-NA)
Sample: Heart
Application: Immunohistochemistry
Wilson, H. et al. (2007) P2X receptor characterization and IL-1/IL-1Ra release from human endothelial cells. Br. J. Pharmacol. 151:115.
Human IL-1 RII Quantikine ELISA Kit (Catalog # DR1B00)
Sample: Human umbilical vein endothelial cell supernates and lysates
Application: ELISA
Human IL-1ra Quantikine ELISA Kit (Catalog # DRA00)
Sample: Human umbilical vein endothelial cell supernates and lysates
Application: ELISA
Human IL-1 beta QuantiGlo® ELISA Kit (Catalog # QLB00B)
Sample: THP-1 human acute monocytic leukemia cell line and human umbilical vein endothelial cell supernates and lysates
Application: ELISA
Human IL-1ra Affinity Purified Polyclonal Antibody (Catalog # AF-280-NA)
Sample: Human umbilical vein endothelial cell supernates and lysates
Application: Western Blot
Human IL-1 alpha Affinity Purified Polyclonal Antibody (Catalog # AF-200-NA)
Sample: THP-1 human acute monocytic leukemia cell line and human umbilical vein endothelial cell supernates and lysates
Application: Western Blot
For information on products for Inflammasome research visit www.RnDSystems.com/go/inflammasome
| Molecule | Recombinant Proteins | Antibodies | ELISAs/Assays |
| ASC | H | ||
| Caspase-1 | H | ||
| Caspase-12 | M R | ||
| IL-1 beta/IL-1F2 | H M R Ca CR E F P Pr | H M R Ca CR E F P | H M R F P |
| IL-1ra/IL-1F3 | H M R E P | H M P E | H M |
| IL-1 RI | H M | H M | H |
| IL-1 RII | H M | H M | H |
| IL-1 R3/IL-1 RAcP | H | H | |
| IL-6 | H M R Ca CR E F P | H M R Ca CR E F P | H M R Ca F P |
| IL-18/IL-1F4 | H M R P Pr | H M R Ca P Pr | H M |
| IL-33 | H M | H M | |
| MyD88 | H M R | H | |
| NAIP | H | ||
| NALP2 | H | ||
| TLR1 | M | H M | |
| TLR2 | H M | H M | |
| TLR3 | H M | H M | |
| TLR4 | H | H M | |
| TLR6 | M | M | |
| TLR9 | H | ||
| Key: H Human M Mouse R Rat Ca Canine CR Cotton Rat E Equine F Feline P Porcine Pr Primate | |||