Simple Protocols & Optimized
Protein Formulations for Differentiation/Expansion
R&D Systems is the world’s premiere source of recombinant proteins. Extensive quality control produces industry leading bioactivity and lot-to-lot consistency that instills confidence in results and ensures reproducibility.
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Bulk Recombinant Proteins
There is no need to sacrifice quality and reproducibility to obtain a size and price that matches your research needs. Our Sales Team is ready to discuss pack sizes and economical pricing.
For questions or a quote, please contact us.
Our high quality cytokines and growth factors are available where current Good Manufacturing Practices (GMPs) are required. Our list of available GMP-grade recombinant proteins is expanding regularly.
We offer proteins manufactured in a laboratory exclusively dedicated to the production and purification of recombinant proteins using all non-animal reagents.
Recombinant Protein Quality Control
- Each new lot is tested side-by-side with previous lots for purity, biological potency, and
- Recombinant proteins are typically over 95% pure.
Protein Sequence Accuracy
- N-terminal amino acid sequence analysis is performed for each recombinant protein to verify the correct sequence.
- Bioactivity is measured experimentally with the appropriate biological system.
- Activity is consistent with literature-based expectations if available.
Endotoxin Level and Microbial Bioburden Test
- Each new production lot of protein is assessed for endotoxin using the Limulus Amoebocyte Lysates (LAL) assay. The endotoxin level is typically <0.1EU/ug.
- Each protein is tested to rule out microbial contamination using direct plating and broth dilution, according to guidelines from the United States Pharmacopeia (USP).
- Recombinant proteins are formulated for best stability and are lyophilized from a sterile filtered solution. They are available without or with a carrier protein, usually bovine serum albumin (BSA) at 50 mg/mg of protein.
- Recombinant enzymes are in solution and ready to use.