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Recombinant Mouse IL-6 Protein

Catalog #: 406-ML
363 Citations 15 Reviews Datasheet / COA / SDS

Carrier Free

Catalog # Availability Size / Price Qty
406-ML-005/CF
406-ML-025/CF
406-ML-200/CF

With Carrier

Catalog # Availability Size / Price Qty
406-ML-005
406-ML-025
406-ML-200
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Recombinant Mouse IL-6 Protein Bioactivity
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Product Details
Citations (363)
FAQs
Reviews (15)
Summary Product Datasheets Carrier Free Data Images Reconstitution Calculator Background Related Research Areas

Recombinant Mouse IL-6 Protein Summary

Product Specifications

Purity
>97%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
Endotoxin Level
<0.10 EU per 1 μg of the protein by the LAL method.
Activity
Measured in a cell proliferation assay using T1165.85.2.1 mouse plasmacytoma cells. Nordan, R.P. et al. (1987) J. Immunol. 139:813. The ED50 for this effect is 10.0-100 pg/mL.
Source
E. coli-derived mouse IL-6 protein
Phe25-Thr211, with an N-terminal Met
Accession #
P08505
N-terminal Sequence
Analysis
Phe25
Predicted Molecular Mass
21.8 kDa

Product Datasheets

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406-ML (with carrier)

Product Datasheet
COA
SDS

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406-ML/CF (carrier free)

Product Datasheet
COA
SDS

Carrier Free

What does CF mean?

CF stands for Carrier Free (CF). We typically add Bovine Serum Albumin (BSA) as a carrier protein to our recombinant proteins. Adding a carrier protein enhances protein stability, increases shelf-life, and allows the recombinant protein to be stored at a more dilute concentration. The carrier free version does not contain BSA.

What formulation is right for me?

In general, we advise purchasing the recombinant protein with BSA for use in cell or tissue culture, or as an ELISA standard. In contrast, the carrier free protein is recommended for applications, in which the presence of BSA could interfere.

406-ML

Formulation Lyophilized from a 0.2 μm filtered solution in Sodium Acetate and EDTA with Trehalose and with BSA as a carrier protein.
Reconstitution Reconstitute at 100 μg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin.
Shipping The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 3 months, -20 to -70 °C under sterile conditions after reconstitution.

406-ML/CF

Formulation Supplied as a 0.2 μm filtered solution in Sodium Acetate and EDTA.
Shipping The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Do not freeze.
  • 6 months from date of receipt, 2 to 8 °C as supplied.

Scientific Data

Bioactivity Recombinant Mouse IL-6 Protein Bioactivity View Larger

Recombinant Mouse IL-6 (Catalog # 406‑ML) stimulates cell proliferation of the T1165.85.2.1 mouse plasmacytoma cell line. The ED50 for this effect is 10.0-100 pg/mL.

SDS-PAGE Recombinant Mouse IL-6 Protein SDS-PAGE View Larger

1 μg/lane of Recombinant Mouse IL-6 was resolved with SDS-PAGE under reducing (R) conditions and visualized by silver staining, showing a single band at 24 kDa.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background: IL-6

Interleukin-6 (IL-6) is a pleiotropic, alpha -helical, 22 - 28 kDa phosphorylated and variably glycosylated cytokine that plays important roles in the acute phase reaction, inflammation, hematopoiesis, bone metabolism, and cancer progression (1 - 5). Mature mouse IL-6 is 187 amino acids (aa) in length and shares 39% and 85% aa sequence identity with human and rat IL-6, respectively (6 - 8). IL-6 induces signaling through a cell surface heterodimeric receptor complex composed of a ligand binding subunit (IL-6 R alpha) and a signal transducing subunit (gp130). IL-6 binds to IL-6 R alpha, triggering IL-6 R alpha association with gp130 and gp130 dimerization (9). gp130 is also a component of the receptors for CLC, CNTF, CT-1, IL-11, IL-27, LIF, and OSM (10). Soluble forms of IL-6 R alpha are generated by both alternative splicing and proteolytic cleavage (5). In a mechanism known as trans-signaling, complexes of soluble IL-6 and IL-6 R alpha elicit responses from gp130-expressing cells that lack cell surface IL-6 R alpha (5). Trans-signaling enables a wider range of cell types to respond to IL-6, as the expression of gp130 is ubiquitous, while that of IL-6 R alpha is predominantly restricted to hepatocytes, monocytes, and resting lymphocytes (2, 5). Soluble splice forms of gp130 block trans-signaling from IL-6/IL-6 R alpha but not from other cytokines that use gp130 as a co-receptor (5, 11). IL-6, along with TNF-alpha and IL-1, drives the acute inflammatory response and the transition from acute inflammation to either acquired immunity or chronic inflammatory disease (1 - 5). When dysregulated, it contributes to chronic inflammation in obesity, insulin resistance, inflammatory bowel disease, arthritis, sepsis, and atherosclerosis (1, 2, 5). IL-6 can also function as an anti-inflammatory molecule, as in skeletal muscle where it is secreted in response to exercise (2). In addition, it enhances hematopoietic stem cell proliferation and the differentiation of Th17 cells, memory B cells, and plasma cells (1, 12).

References
  1. Mansell, A. and B.J. Jenkins (2013) Cytokine Growth Factor Rev. 24:249.
  2. Schuett, H. et al. (2009) Thromb. Haemost. 102:215.
  3. Erta, M. et al. (2012) Int. J. Biol. Sci. 8:1254.
  4. Garbers, C. et al. (2012) Cytokine Growth Factor Rev. 23:85.
  5. Mihara, M. et al. (2012) Clin. Sci. (Lond.) 122:143.
  6. Chiu, C.P. et al. (1988) Proc. Natl. Acad. Sci. USA 85:7099.
  7. Simpson, R.J. et al. (1988) Eur. J. Biochem. 176:187.
  8. Van Snick, J. et al. (1988) Eur. J. Immunol. 18:193.
  9. Murakami, M. et al. (1993) Science 260:1808.
  10. Muller-Newen, G. (2003) Sci. STKE 2003:PE40.
  11. Mitsuyama, K. et al. (2006) Clin. Exp. Immunol. 143:125.
  12. Cerutti, A. et al. (1998) J. Immunol. 160:2145.
Long Name
Interleukin 6
Entrez Gene IDs
3569 (Human); 16193 (Mouse); 24498 (Rat); 399500 (Porcine); 280826 (Bovine); 403985 (Canine); 102138971 (Cynomolgus Monkey); 100034196 (Equine); 493687 (Feline); 463288 (Primate); 100008733 (Rabbit)
Alternate Names
B-cell differentiation factor; B-cell stimulatory factor 2; BSF2; BSF-2; CDF; CTL differentiation factor ; HSF; hybridoma growth factor; IFNB2; IFN-beta-2; IL6; IL-6; Interferon beta-2; interleukin 6 (interferon, beta 2); interleukin BSF-2; interleukin-6; MGI-2A

Citations for Recombinant Mouse IL-6 Protein

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

363 Citations: Showing 1 - 10
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  1. CSF1R Ligands Expressed by Murine Gliomas Promote M-MDSCs to Suppress CD8+ T Cells in a NOS-Dependent Manner
    Authors: Takacs, GP;Garcia, JS;Hodges, CA;Kreiger, CJ;Sherman, A;Harrison, JK;
    Cancers
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  2. SETDB1 suppresses NK cell-mediated immunosurveillance in acute myeloid leukemia with granulo-monocytic differentiation
    Authors: Chang, YH;Yamamoto, K;Fujino, T;Wang, TW;Sugimoto, E;Zhang, W;Yabushita, T;Suzaki, K;Pietsch, EC;Weir, BA;Crescenzo, R;Cowley, GS;Attar, R;Philippar, U;Wunderlich, M;Mizukawa, B;Zheng, Y;Enomoto, Y;Imai, Y;Kitamura, T;Goyama, S;
    Cell reports
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  3. MicroRNA-19b exacerbates systemic sclerosis through promoting Th9 cells
    Authors: Lim, YJ;Park, SA;Wang, D;Jin, W;Ku, WL;Zhang, D;Xu, J;Patiño, LC;Liu, N;Chen, W;Kazmi, R;Zhao, K;Zhang, YE;Sun, L;Chen, W;
    Cell reports
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  4. BACH2 regulates diversification of regulatory and proinflammatory chromatin states in TH17 cells
    Authors: Thakore, PI;Schnell, A;Huang, L;Zhao, M;Hou, Y;Christian, E;Zaghouani, S;Wang, C;Singh, V;Singaraju, A;Krishnan, RK;Kozoriz, D;Ma, S;Sankar, V;Notarbartolo, S;Buenrostro, JD;Sallusto, F;Patsopoulos, NA;Rozenblatt-Rosen, O;Kuchroo, VK;Regev, A;
    Nature immunology
    Species: Mouse, Transgenic Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  5. Oncogenic KRAS-dependent stromal interleukin-33 directs the pancreatic microenvironment to promote tumor growth
    Authors: Donahue, KL;Watkoske, HR;Kadiyala, P;Du, W;Brown, K;Scales, MK;Elhossiny, AM;Espinoza, CE;Lasse Opsahl, EL;Griffith, BD;Wen, Y;Sun, L;Velez-Delgado, A;Renollet, NM;Morales, J;Nedzesky, NM;Baliira, RK;Menjivar, RE;Medina-Cabrera, PI;Rao, A;Allen, B;Shi, J;Frankel, TL;Carpenter, ES;Bednar, F;Zhang, Y;Pasca di Magliano, M;
    Cancer discovery
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  6. Stem-like T cells are associated with the pathogenesis of ulcerative colitis in humans
    Authors: Li, Y;Ramírez-Suástegui, C;Harris, R;Castañeda-Castro, FE;Ascui, G;Pérez-Jeldres, T;Diaz, A;Morong, C;Giles, DA;Chai, J;Seumois, G;Sanchez-Elsner, T;Cummings, F;Kronenberg, M;Vijayanand, P;
    Nature immunology
    Species: Mouse, Transgenic Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  7. Glioma-derived M-CSF and IL-34 license M-MDSCs to suppress CD8+ T cells in a NOS-dependent manner
    Authors: Takacs, GP;Garcia, JS;Hodges, CA;Kreiger, CJ;Sherman, A;Harrison, JK;
    bioRxiv : the preprint server for biology
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  8. Pancreatic epithelial IL-17/IL-17RA signaling drives B7-H4 expression to promote tumorigenesis
    Authors: Castro-Pando, S;Howell, RM;Li, L;Mascaro, M;Faraoni, EY;Le Roux, O;Romanin, D;Tahan, V;Riquelme, E;Zhang, Y;Kolls, JK;Allison, JP;Lozano, G;Moghaddam, SJ;McAllister, F;
    Cancer immunology research
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  9. Design, synthesis, and biological evaluation of novel sesquiterpene lactone derivatives as PKM2 activators with potent anti-ulcerative colitis activities
    Authors: Ma, L;Li, M;Lv, J;Yuan, Q;Yin, X;Lu, W;Lin, W;Wang, P;Cui, J;Lv, Q;Liu, J;Hu, L;
    European journal of medicinal chemistry
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  10. Type 1 interferons and Foxo1 down-regulation play a key role in age-related T-cell exhaustion in mice
    Authors: Durand, A;Bonilla, N;Level, T;Ginestet, Z;Lombès, A;Guichard, V;Germain, M;Jacques, S;Letourneur, F;Do Cruzeiro, M;Marchiol, C;Renault, G;Le Gall, M;Charvet, C;Le Bon, A;Martin, B;Auffray, C;Lucas, B;
    Nature communications
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  11. CaMK4 controls follicular helper T cell expansion and function during normal and autoimmune T-dependent B cell responses
    Authors: Scherlinger, M;Li, H;Pan, W;Li, W;Karino, K;Vichos, T;Boulougoura, A;Yoshida, N;Tsokos, MG;Tsokos, GC;
    Nature communications
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  12. Trappc1 intrinsically prevents ferroptosis of naive T cells to avoid spontaneous autoinflammatory disease in mice
    Authors: Zhang, Z;Zhao, C;Sun, L;Cheng, C;Tian, Q;Wu, C;Xu, Y;Dong, X;Zhang, B;Zhang, L;Zhao, Y;
    European journal of immunology
    Species: Mouse, Transgenic Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  13. Interleukin-17-mediated protective cytokine signaling against degeneration of the retinal pigment epithelium
    Authors: Chen, Y;Bounds, SE;Ma, X;Karmoker, JR;Liu, Y;Ma, JX;Cai, J;
    Proceedings of the National Academy of Sciences of the United States of America
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  14. Nanoparticles of Lactiplantibacillus plantarum K8 Reduce Staphylococcus aureus Respiratory Infection and Tumor Necrosis Factor Alpha- and Interferon Gamma-Induced Lung Inflammation
    Authors: Hong, J;Son, M;Sin, J;Kim, H;Chung, DK;
    Nutrients
    Species: Mouse
    Sample Types: Serum
    Applications: ELISA Control
  15. SARS-CoV-2 induces acute neurological signs while Calcitonin Gene-Related Peptide (CGRP) signaling blockade reduces interleukin 6 (IL-6) release and weight loss in mouse models
    Authors: Rahman, SM;Buchholz, DW;Imbiakha, B;Jager, MC;Leach, J;Osborn, RM;Birmingham, AO;Dewhurst, S;Aguilar, HC;Luebke, AE;
    bioRxiv : the preprint server for biology
    Species: N/A
    Sample Types: Antibody
    Applications: ELISA Standard
  16. Polarized microtubule remodeling transforms the morphology of reactive microglia and drives cytokine release
    Authors: Adrian, M;Weber, M;Tsai, MC;Glock, C;Kahn, OI;Phu, L;Cheung, TK;Meilandt, WJ;Rose, CM;Hoogenraad, CC;
    Nature communications
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  17. Gut microbial metabolite deoxycholic acid facilitates Th17 differentiation through modulating cholesterol biosynthesis and participates in high-fat diet-associated colonic inflammation
    Authors: Li, D;Zhou, J;Wang, L;Gong, Z;Le, H;Huang, Y;Xu, C;Tian, C;Cai, W;Wu, J;
    Cell & bioscience
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  18. Single-cell lineage capture across genomic modalities with CellTag-multi reveals fate-specific gene regulatory changes
    Authors: Jindal, K;Adil, MT;Yamaguchi, N;Yang, X;Wang, HC;Kamimoto, K;Rivera-Gonzalez, GC;Morris, SA;
    Nature biotechnology
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  19. CD8+ T cells reduce neuroretina inflammation in mouse by regulating autoreactive Th1 and Th17 cells through IFN-?
    Authors: Wu, S;Zhang, X;Hu, C;Zhong, Y;Chen, J;Chong, WP;
    European journal of immunology
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  20. CD40L modulates CD4+ T cell activation through receptor for activated C kinase 1
    Authors: van Os, BW;Vos, WG;Bosmans, LA;van Tiel, CM;Toom, MD;Beckers, L;Admiraal, M;Hoeksema, MA;de Winther, MP;Lutgens, E;
    European journal of immunology
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  21. Aminooxy acetic acid suppresses Th17-mediated psoriasis-like skin inflammation by inhibiting serine metabolism
    Authors: Lee, JY;Lee, JH;Lim, HJ;Kim, E;Kim, DK;Choi, JK;
    Frontiers in pharmacology
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  22. In vivo screening characterizes chromatin factor functions during normal and malignant hematopoiesis
    Authors: Lara-Astiaso, D;Goñi-Salaverri, A;Mendieta-Esteban, J;Narayan, N;Del Valle, C;Gross, T;Giotopoulos, G;Beinortas, T;Navarro-Alonso, M;Aguado-Alvaro, LP;Zazpe, J;Marchese, F;Torrea, N;Calvo, IA;Lopez, CK;Alignani, D;Lopez, A;Saez, B;Taylor-King, JP;Prosper, F;Fortelny, N;Huntly, BJP;
    Nature genetics
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  23. IL-22 Is Deleterious along with IL-17 in Allergic Asthma but Is Not Detrimental in the Comorbidity Asthma and Acute Pneumonia
    Authors: Goulart, A;Boko, MMM;Martins, NS;Gembre, AF;de Oliveira, RS;Palma-Albornoz, SP;Bertolini, T;Ribolla, PEM;Ramalho, LNZ;Fraga-Silva, TFC;Bonato, VLD;
    International journal of molecular sciences
    Species: Mouse, Transgenic Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  24. Cytokine-Induced Myeloid-Derived Suppressor Cells Demonstrate Their Immunoregulatory Functions to Prolong the Survival of Diabetic Mice
    Authors: Li, TT;Lin, CL;Chiang, M;He, JT;Hung, CH;Hsieh, CC;
    Cells
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  25. Predicting gene level sensitivity to JAK-STAT signaling perturbation using a mechanistic-to-machine learning framework
    Authors: Cheemalavagu, N;Shoger, KE;Cao, YM;Michalides, BA;Botta, SA;Faeder, JR;Gottschalk, RA;
    bioRxiv : the preprint server for biology
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  26. Magnesium increases numbers of Foxp3+ Treg cells and reduces arthritis severity and joint damage in an IL-10-dependent manner mediated by the intestinal microbiome
    Authors: Laragione, T;Harris, C;Azizgolshani, N;Beeton, C;Bongers, G;Gulko, PS;
    EBioMedicine
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  27. IL-18 is required for the TH1-adaptation of TREG cells and the selective suppression of TH17 responses in acute and chronic infections
    Authors: Alvarez, F;Istomine, R;Da Silva Lira Filho, A;Al-Aubodah, TA;Huang, D;Okde, R;Olivier, M;Fritz, JH;Piccirillo, CA;
    Mucosal immunology
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  28. EDA2R-NIK signalling promotes muscle atrophy linked to cancer cachexia
    Authors: Bilgic, SN;Domaniku, A;Toledo, B;Agca, S;Weber, BZC;Arabaci, DH;Ozornek, Z;Lause, P;Thissen, JP;Loumaye, A;Kir, S;
    Nature
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  29. ITK signaling regulates a switch between T helper 17 and T regulatory cell lineages via a calcium-mediated pathway
    Authors: O Anannya, W Huang, A August
    bioRxiv : the preprint server for biology, 2023-04-03;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  30. The RNA-binding protein hnRNP F is required for the germinal center B cell response
    Authors: H Huang, Y Li, G Zhang, GX Ruan, Z Zhu, W Chen, J Zou, R Zhang, J Wang, Y Ouyang, S Xu, X Ou
    Nature Communications, 2023-03-30;14(1):1731.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  31. Aiolos represses CD4+ T cell cytotoxic programming via reciprocal regulation of TFH transcription factors and IL-2 sensitivity
    Authors: KA Read, DM Jones, S Pokhrel, EDS Hales, A Varkey, JA Tuazon, CD Eisele, O Abdouni, A Saadey, MR Leonard, RT Warren, MD Powell, JM Boss, EA Hemann, JS Yount, G Xin, HE Ghoneim, CJ Lio, AG Freud, PL Collins, KJ Oestreich
    Nature Communications, 2023-03-24;14(1):1652.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  32. Latexin regulates sex dimorphism in hematopoiesis via gender-specific differential expression of microRNA 98-3p and thrombospondin 1
    Authors: X Cui, C Zhang, F Wang, X Zhao, S Wang, J Liu, D He, C Wang, FC Yang, S Tong, Y Liang
    Cell Reports, 2023-03-16;42(3):112274.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  33. BAFF induces CXCR5 expression during B cell differentiation in bone marrow
    Authors: H Koizumi, W Fujii, C Sanjoba, Y Goto
    Biochemistry and Biophysics Reports, 2023-03-07;34(0):101451.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  34. Experimental venous thrombus resolution is driven by IL-6 mediated monocyte actions
    Authors: AT Obi, SB Sharma, MA Elfline, CE Luke, AR Dowling, Q Cai, AS Kimball, M Hollinstat, L Stanger, BB Moore, FA Jaffer, PK Henke
    Scientific Reports, 2023-02-24;13(1):3253.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  35. Modulation of Skin Inflammatory Responses by Aluminum Adjuvant
    Authors: Y Liao, L Sun, M Nie, J Li, X Huang, S Heng, W Zhang, T Xia, Z Guo, Q Zhao, LJ Zhang
    Pharmaceutics, 2023-02-08;15(2):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  36. RNA binding protein DDX5 restricts RORgammat+ Treg suppressor function to promote intestine inflammation
    Authors: S Ma, Q Yang, N Chen, A Zheng, N Abbasi, G Wang, PR Patel, BS Cho, BA Yee, L Zhang, H Chu, SM Evans, GW Yeo, Y Zheng, WJM Huang
    Science Advances, 2023-02-01;9(5):eadd6165.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  37. NR4A1 agonist cytosporone B attenuates neuroinflammation in a mouse model of multiple sclerosis
    Authors: HZ Yu, BQ Zhu, L Zhu, S Li, LM Wang
    Oncogene, 2022-12-01;17(12):2765-2770.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  38. IMPDH inhibition activates TLR-VCAM1 pathway and suppresses the development of MLL-fusion leukemia
    Authors: X Liu, N Sato, T Yabushita, J Li, Y Jia, M Tamura, S Asada, T Fujino, T Fukushima, T Yonezawa, Y Tanaka, T Fukuyama, A Tsuchiya, S Shikata, H Iwamura, C Kinouchi, K Komatsu, S Yamasaki, T Shibata, AT Sasaki, J Schibler, M Wunderlich, E O'Brien, B Mizukawa, JC Mulloy, Y Sugiura, H Takizawa, T Shibata, K Miyake, T Kitamura, S Goyama
    Embo Molecular Medicine, 2022-12-01;0(0):e15631.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  39. Phosphofructokinase P fine-tunes T regulatory cell metabolism, function, and stability in systemic autoimmunity
    Authors: M Scherlinge, W Pan, R Hisada, A Boulougour, N Yoshida, M Vukelic, M Umeda, S Krishfield, MG Tsokos, GC Tsokos
    Science Advances, 2022-11-30;8(48):eadc9657.
    Species: Transgenic Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  40. IL6 supports long-term expansion of hepatocytes in vitro
    Authors: R Guo, M Jiang, G Wang, B Li, X Jia, Y Ai, S Chen, P Tang, A Liu, Q Yuan, X Xie
    Nature Communications, 2022-11-29;13(1):7345.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  41. EC-18 prevents autoimmune arthritis by suppressing inflammatory cytokines and osteoclastogenesis
    Authors: JS Park, SC Yang, HY Jeong, SY Lee, JG Ryu, JW Choi, HY Kang, SM Kim, SH Hwang, ML Cho, SH Park
    Arthritis Research & Therapy, 2022-11-17;24(1):254.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  42. Epigenetic drug screen identified IOX1 as an inhibitor of Th17-mediated inflammation through targeting TET2
    Authors: X Hu, Y Zou, DA Copland, LP Schewitz-B, Y Li, PJP Lait, M Stimpson, Z Zhang, S Guo, J Liang, T Chen, JJ Li, S Yuan, S Li, P Zhou, Y Liu, AD Dick, X Wen, RWJ Lee, L Wei
    EBioMedicine, 2022-11-03;86(0):104333.
    Species: Mouse, Transgenic Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  43. Opposing functions of circadian protein DBP and atypical E2F family E2F8 in anti-tumor Th9 cell differentiation
    Authors: SA Park, YJ Lim, WL Ku, D Zhang, K Cui, LY Tang, C Chia, P Zanvit, Z Chen, W Jin, D Wang, J Xu, O Liu, F Wang, A Cain, N Guo, H Nakatsukas, C Wu, YE Zhang, K Zhao, W Chen
    Nature Communications, 2022-10-14;13(1):6069.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  44. IL-3 regulates the differentiation of pathogenic Th17 cells
    Authors: L Rani, A Kumar, J Karhade, G Pandey, A Guha, GC Mishra, MR Wani
    European Journal of Immunology, 2022-09-26;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  45. Traject3d allows label-free identification of distinct co-occurring phenotypes within 3D culture by live imaging
    Authors: EC Freckmann, E Sandilands, E Cumming, M Neilson, A Román-Fern, K Nikolatou, M Nacke, TRM Lannagan, A Hedley, D Strachan, M Salji, JP Morton, L McGarry, HY Leung, OJ Sansom, CJ Miller, DM Bryant
    Nature Communications, 2022-09-09;13(1):5317.
    Species: Mouse
    Sample Types: Organoid
    Applications: Bioassay
  46. The trophectoderm acts as a niche for the inner cell mass through C/EBPalpha-regulated IL-6 signaling
    Authors: M Plana-Carm, G Stik, R Bulteau, C Segura-Mor, N Alcázar, CDR Wyatt, A Klonizakis, L de Andrés-, M Gasnier, TV Tian, G Torcal Gar, M Vila-Casad, N Plachta, M Serrano, M Francescon, T Graf
    Stem Cell Reports, 2022-08-11;0(0):.
    Species: Mouse
    Sample Types: Whole Cell
    Applications: Cell Culture
  47. hUC-EVs-ATO reduce the severity of acute GVHD by resetting inflammatory macrophages toward the M2 phenotype
    Authors: Y Su, X Sun, X Liu, Q Qu, L Yang, Q Chen, F Liu, Y Li, Q Wang, B Huang, XJ Huang, XH Zhang
    Journal of hematology & oncology, 2022-07-21;15(1):99.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  48. A cannabidiol aminoquinone derivative activates the PP2A/B55alpha/HIF pathway and shows protective effects in a murine model of traumatic brain injury
    Authors: C Navarrete, A García-Mar, A Correa-Sáe, ME Prados, F Fernández, R Pineda, M Mazzone, M Álvarez-Be, MA Calzado, E Muñoz
    Journal of Neuroinflammation, 2022-07-09;19(1):177.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  49. Hematopoietic Prostaglandin D2 Synthase Controls Tfh/Th2 Communication and Limits Tfh Antitumor Effects
    Authors: R Mary, F Chalmin, T Accogli, M Bruchard, C Hibos, J Melin, C Truntzer, E Limagne, V Derangère, M Thibaudin, E Humblin, R Boidot, S Chevrier, L Arnould, C Richard, Q Klopfenste, A Bernard, Y Urade, JA Harker, L Apetoh, F Ghiringhel, F Végran
    Cancer Immunology Research, 2022-07-01;0(0):OF1-OF17.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  50. Semaphorin 3A regulates alveolar bone remodeling on orthodontic tooth movement
    Authors: H Kamei, T Ishii, Y Nishii
    Oncogene, 2022-06-02;12(1):9243.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  51. Cryptotanshinone ameliorates dextran sulfate sodium-induced murine acute and chronic ulcerative colitis via suppressing STAT3 activation and Th17 cell differentiation
    Authors: LM Fan, YQ Zhang, YP Chen, LL Chen, WH Xu, LH Nan, W Xu, B Lu, Y Wang, KD Chu, JP Zhang
    Oncogene, 2022-05-31;108(0):108894.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  52. Acetylation licenses Th1 cell polarization to constrain Listeria monocytogenes infection
    Authors: YS Zhang, DE Xin, Z Wang, W Peng, Y Zeng, J Liang, M Xu, N Chen, J Zhang, J Yue, M Cao, C Zhang, Y Wang, Z Chang, XM Lu, L Chang, YE Chinn
    Cell Death and Differentiation, 2022-05-25;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  53. STING is an intrinsic checkpoint inhibitor that restrains the TH17 cell pathogenic program
    Authors: LEA Damasceno, GCM Cebinelli, MF Fernandes, DC Nascimento, GA Públio, MAR Vinolo, SC Oliveira, T Sparwasser, TM Cunha, FQ Cunha, JC Alves-Filh
    Cell Reports, 2022-05-24;39(8):110838.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  54. MDS cells impair osteolineage differentiation of MSCs via extracellular vesicles to suppress normal hematopoiesis
    Authors: Y Hayashi, KC Kawabata, Y Tanaka, Y Uehara, Y Mabuchi, K Murakami, A Nishiyama, S Kiryu, Y Yoshioka, Y Ota, T Sugiyama, K Mikami, M Tamura, T Fukushima, S Asada, R Takeda, Y Kunisaki, T Fukuyama, K Yokoyama, T Uchida, M Hagihara, N Ohno, K Usuki, A Tojo, Y Katayama, S Goyama, F Arai, T Tamura, T Nagasawa, T Ochiya, D Inoue, T Kitamura
    Cell Reports, 2022-05-10;39(6):110805.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  55. The myokine Fibcd1 is an endogenous determinant of myofiber size and mitigates cancer-induced myofiber atrophy
    Authors: FA Graca, M Rai, LC Hunt, A Stephan, YD Wang, B Gordon, R Wang, G Quarato, B Xu, Y Fan, M Labelle, F Demontis
    Nature Communications, 2022-05-02;13(1):2370.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Bioassay
  56. CD4+ T-cell-derived IL-10 promotes CNS inflammation in mice by sustaining effector T�cell survival
    Authors: N Yogev, T Bedke, Y Kobayashi, L Brockmann, D Lukas, T Regen, AL Croxford, A Nikolav, N Hövelmeyer, E von Stebut, M Prinz, C Ubeda, KJ Maloy, N Gagliani, RA Flavell, A Waisman, S Huber
    Cell Reports, 2022-03-29;38(13):110565.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  57. Hyperphosphatemia increases inflammation to exacerbate anemia and skeletal muscle wasting independently of FGF23-FGFR4 signaling
    Authors: B Czaya, K Heitman, I Campos, C Yanucil, D Kentrup, D Westbrook, O Gutierrez, JL Babitt, G Jung, IB Salusky, M Hanudel, C Faul
    Elife, 2022-03-18;11(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  58. RORgammat phosphorylation protects against T�cell-mediated inflammation
    Authors: S Ma, SA Patel, Y Abe, N Chen, PR Patel, BS Cho, N Abbasi, S Zeng, B Schnabl, JT Chang, WJM Huang
    Cell Reports, 2022-03-15;38(11):110520.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  59. Mosaic loss of chromosome Y promotes leukemogenesis and clonal hematopoiesis
    Authors: Q Zhang, L Zhao, Y Yang, S Li, Y Liu, C Chen
    JCI Insight, 2022-02-08;7(3):.
  60. Bi-phasic effect of gelatin in myogenesis and skeletal muscle regeneration
    Authors: X Liu, E Zu, X Chang, X Ma, Z Wang, X Song, X Li, Q Yu, KI Kamei, T Hayashi, K Mizuno, S Hattori, H Fujisaki, T Ikejima, DO Wang
    Disease Models & Mechanisms, 2021-12-24;14(12):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  61. CD147 Is Essential for the Development of Psoriasis via the Induction of Th17 Cell Differentiation
    Authors: A Okubo, Y Uchida, Y Higashi, T Sato, Y Ogawa, A Ryuge, K Kadomatsu, T Kanekura
    International Journal of Molecular Sciences, 2021-12-24;23(1):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  62. Epigenetic drug ameliorated type 1 diabetes via decreased generation of Th1 and Th17 subsets and restoration of self-tolerance in CD4+ T cells
    Authors: V Patel, A Jayaraman, S Jayaraman
    International immunopharmacology, 2021-12-23;103(0):108490.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  63. Modestly increasing systemic interleukin-6 perinatally disturbs secondary germinal zone neurogenesis and gliogenesis and produces sociability deficits
    Authors: FJ Velloso, A Wadhwa, E Kumari, I Carcea, O Gunal, SW Levison
    Brain, Behavior, and Immunity, 2021-12-23;101(0):23-36.
    Species: Mouse
    Sample Types: In Vivo
    Applications: Bioassay
  64. Differential Cytokine-Induced Responses of Polarized Microglia
    Authors: P Chauhan, WS Sheng, S Hu, S Prasad, JR Lokensgard
    Brain sciences, 2021-11-10;11(11):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  65. The effect of macrophage polarization on the expression of the oxytocin signalling system in enteric neurons
    Authors: Y Shi, S Li, H Zhang, J Zhu, T Che, B Yan, J Li, C Liu
    Journal of Neuroinflammation, 2021-11-08;18(1):261.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  66. Leukemic progenitor cells enable immunosuppression and post-chemotherapy relapse via IL-36-inflammatory monocyte axis
    Authors: HZ Guo, ZH Guo, SH Yu, LT Niu, WT Qiang, MM Huang, YY Tian, J Chen, H Yang, XQ Weng, Y Zhang, W Zhang, SY Hu, J Shi, J Zhu
    Science Advances, 2021-10-08;7(41):eabg4167.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  67. Macrophage-derived interleukin-6 is necessary and sufficient for choroidal angiogenesis
    Authors: S Droho, CM Cuda, H Perlman, JA Lavine
    Scientific Reports, 2021-09-10;11(1):18084.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Bioassay
  68. Elevated beta-secretase 1 expression mediates CD4+ T cell dysfunction via PGE2 signalling in Alzheimer's disease
    Authors: L Dai, Q Wang, X Lv, F Gao, Z Chen, Y Shen
    Brain, Behavior, and Immunity, 2021-09-06;98(0):337-348.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  69. A histone modifier, ASXL1, interacts with NONO and is involved in paraspeckle formation in hematopoietic cells
    Authors: K Yamamoto, S Goyama, S Asada, T Fujino, T Yonezawa, N Sato, R Takeda, A Tsuchiya, T Fukuyama, Y Tanaka, A Yokoyama, H Toya, A Kon, Y Nannya, R Onoguchi-M, S Nakagawa, T Hirose, S Ogawa, N Akimitsu, T Kitamura
    Cell Reports, 2021-08-24;36(8):109576.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  70. Interferon-beta Intensifies Interleukin-23-Driven Pathogenicity of T Helper Cells in Neuroinflammatory Disease
    Authors: A Agasing, JL Quinn, G Kumar, RC Axtell
    Cells, 2021-08-20;10(8):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  71. TCF-1 controls Treg cell functions that regulate inflammation, CD8+ T cell cytotoxicity and severity of colon cancer
    Authors: A Osman, B Yan, Y Li, KD Pavelko, J Quandt, A Saadalla, MP Singh, M Kazemian, F Gounari, K Khazaie
    Nature Immunology, 2021-08-12;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  72. Essential role of a ThPOK autoregulatory loop in the maintenance of mature CD4+ T cell identity and function
    Authors: J Basu, BS Reis, S Peri, J Zha, X Hua, L Ge, K Ferchen, E Nicolas, P Czyzewicz, KQ Cai, Y Tan, JI Fuxman Bas, AJM Walhout, HL Grimes, SI Grivenniko, D Mucida, DJ Kappes
    Nature Immunology, 2021-07-26;22(8):969-982.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  73. GLT1 gene delivery based on bone marrow-derived cells ameliorates motor function and survival in a mouse model of ALS
    Authors: N Ohashi, T Terashima, M Katagi, Y Nakae, J Okano, Y Suzuki, H Kojima
    Scientific Reports, 2021-06-17;11(1):12803.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  74. m6A demethylase ALKBH5 controls CD4+ T cell pathogenicity and promotes autoimmunity
    Authors: J Zhou, X Zhang, J Hu, R Qu, Z Yu, H Xu, H Chen, L Yan, C Ding, Q Zou, Y Ye, Z Wang, RA Flavell, HB Li
    Science Advances, 2021-06-16;7(25):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  75. MLKL promotes cellular differentiation in myeloid leukemia by facilitating the release of G-CSF
    Authors: X Wang, U Ros, D Agrawal, EC Keller, J Slotta-Hus, V Dill, B Shen, R Shi, T Herold, C Belka, R Misra, F Bassermann, AJ Garcia-Sae, PJ Jost
    Cell Death and Differentiation, 2021-06-02;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  76. Identification of Small Molecule Inhibitors of a Mir155 Transcriptional Reporter in Th17 Cells
    Authors: A Singh, M Dashynam, B Chim, TM Escobar, X Liu, X Hu, S Patnaik, X Xu, N Southall, J Marugan, A Jadhav, V Lazarevic, SA Muljo, M Ferrer
    Scientific Reports, 2021-06-01;11(1):11498.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  77. NLRP1 acts as a negative regulator of Th17 cell programming in mice and humans with autoimmune diabetes
    Authors: FRC Costa, JA Leite, DM Rassi, JF da Silva, J Elias-Oliv, JB Guimarães, MC Foss-Freit, NOS Câmara, A Pontillo, RC Tostes, JS Silva, D Carlos
    Cell Reports, 2021-05-25;35(8):109176.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  78. The YAP/HIF-1&alpha/miR-182/EGR2 axis is implicated in asthma severity through the control of Th17 cell differentiation
    Authors: J Zhou, N Zhang, W Zhang, C Lu, F Xu
    Cell & bioscience, 2021-05-12;11(1):84.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  79. IL-6 Promotes the Proliferation and Immunosuppressive Function of Myeloid-Derived Suppressor Cells via the MAPK Signaling Pathway in Bladder Cancer
    Authors: Z Zheng, X Zheng, Y Zhu, Z Yao, W Zhao, Y Zhu, F Sun, X Mu, Y Wang, W He, Z Liu, K Wu, J Zheng
    BioMed Research International, 2021-04-23;2021(0):5535578.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  80. CAR directs T cell adaptation to bile acids in the small intestine
    Authors: ML Chen, X Huang, H Wang, C Hegner, Y Liu, J Shang, A Eliason, H Diao, H Park, B Frey, G Wang, SA Mosure, LA Solt, DJ Kojetin, A Rodriguez-, DA Schady, CT Weaver, ME Pipkin, DD Moore, MS Sundrud
    Nature, 2021-04-07;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  81. Agonist anti-ChemR23 mAb reduces tissue neutrophil accumulation and triggers chronic inflammation resolution
    Authors: C Trilleaud, V Gauttier, K Biteau, I Girault, L Belarif, C Mary, S Pengam, G Teppaz, V Thepenier, R Danger, G Robert-Sie, M Néel, S Bruneau, A Glémain, A Néel, A Poupon, JF Mosnier, G Chêne, M Dubourdeau, G Blancho, B Vanhove, N Poirier
    Science Advances, 2021-04-02;7(14):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  82. Sprouty2 positively regulates T cell function and airway inflammation through regulation of CSK and LCK kinases
    Authors: A Sripada, K Sirohi, L Michalec, L Guo, JT McKay, S Yadav, M Verma, J Good, D Rollins, MM Gorska, R Alam
    PloS Biology, 2021-03-08;19(3):e3001063.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  83. Signal-transducing adaptor protein-2 delays recovery of B lineage lymphocytes during hematopoietic stress
    Authors: M Ichii, K Oritani, J Toda, H Saito, H Shi, H Shibayama, D Motooka, Y Kitai, R Muromoto, JI Kashiwakur, K Saitoh, D Okuzaki, T Matsuda, Y Kanakura
    Haematologica, 2021-02-01;0(0):.
    Species: Mouse
    Sample Types: Whole Cell
    Applications: Cell Culture
  84. Myocyte-specific enhancer factor 2c triggers transdifferentiation of adipose tissue-derived stromal cells into spontaneously beating cardiomyocyte-like cells
    Authors: S Takashima, S Usui, O Inoue, C Goten, K Yamaguchi, Y Takeda, S Cui, Y Sakai, K Hayashi, K Sakata, MA Kawashiri, M Takamura
    Scientific Reports, 2021-01-15;11(1):1520.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  85. A role for protease activated receptor type 3 (PAR3) in nociception demonstrated through development of a novel peptide agonist
    Authors: J Mwirigi, M Kume, SN Hassler, A Ahmad, PR Ray, C Jiang, A Chamessian, N Mseeh, BP Ludwig, BD Rivera, MT Nieman, TV de Ven, RR Ji, G Dussor, S Boitano, J Vagner, TJ Price
    The journal of pain, 2021-01-09;0(0):.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  86. Microglial inflammation after chronic spinal cord injury is enhanced by reactive astrocytes via the fibronectin/&beta1 integrin pathway
    Authors: S Yoshizaki, T Tamaru, M Hara, K Kijima, M Tanaka, DJ Konno, Y Matsumoto, Y Nakashima, S Okada
    Journal of Neuroinflammation, 2021-01-06;18(1):12.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  87. The ATP synthase inhibition induces an AMPK-dependent glycolytic switch of mesenchymal stem cells that enhances their immunotherapeutic potential
    Authors: R Contreras-, R Elizondo-V, N Luque-Camp, MJ Torres, C Pradenas, G Tejedor, MJ Paredes-Ma, AM Vega-Lette, M Campos-Mor, Y Rigual-Gon, K Oyarce, M Salgado, C Jorgensen, M Khoury, MLÁ Garcia-Rob, C Altamirano, F Djouad, P Luz-Crawfo
    Theranostics, 2021-01-01;11(1):445-460.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  88. Myeloid-derived suppressor cells therapy enhance immunoregulatory properties in acute graft versus host disease with combination of regulatory T cells
    Authors: MJ Park, JA Baek, SY Kim, KA Jung, JW Choi, SH Park, SK Kwok, ML Cho
    Journal of Translational Medicine, 2020-12-14;18(1):483.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  89. Authentication of Primary Murine Cell Lines by a Microfluidics-Based Lab-On-Chip System
    Authors: Y Hong, N Singh, S Bamopoulos, E Gjerga, LK Schmalbroc, K Balabanian, M Schick, U Keller, M Wirth
    Biomedicines, 2020-12-09;8(12):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  90. Maternal immune activation induces sustained changes in fetal microglia motility
    Authors: K Ozaki, D Kato, A Ikegami, A Hashimoto, S Sugio, Z Guo, M Shibushita, T Tatematsu, K Haruwaka, AJ Moorhouse, H Yamada, H Wake
    Scientific Reports, 2020-12-07;10(1):21378.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  91. The frequency of follicular T helper cells differs in acute and chronic neuroinflammation
    Authors: A Baniahmad, K Birkner, J Görg, J Loos, F Zipp, B Wasser, S Bittner
    Sci Rep, 2020-11-24;10(1):20485.
    Species: Transgenic Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  92. An IL-27-Driven Transcriptional Network Identifies Regulators of IL-10 Expression across T Helper Cell Subsets
    Authors: H Zhang, A Madi, N Yosef, N Chihara, A Awasthi, C Pot, C Lambden, A Srivastava, PR Burkett, J Nyman, E Christian, Y Etminan, A Lee, H Stroh, J Xia, K Karwacz, PI Thakore, N Acharya, A Schnell, C Wang, L Apetoh, O Rozenblatt, AC Anderson, A Regev, VK Kuchroo
    Cell Rep, 2020-11-24;33(8):108433.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  93. Quantification of Citrullinated Histone H3 Bound DNA for Detection of Neutrophil Extracellular Traps
    Authors: M Li, C Lin, A Leso, Y Nefedova
    Cancers (Basel), 2020-11-18;12(11):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  94. Endogenous DEL-1 restrains melanoma lung metastasis by limiting myeloid cell-associated lung inflammation
    Authors: YM Hyun, SU Seo, WS Choi, HJ Kwon, DY Kim, S Jeong, GY Kang, E Yi, M Kim, HJ Ryu, MR Looney, EY Choi, HS Kim
    Sci Adv, 2020-11-06;6(45):.
    Species: Mouse
    Sample Types: In Vivo, Whole Cells
    Applications: Bioassay, In Vivo
  95. In Vivo Pre-Instructed HSCs Robustly Execute Asymmetric Cell Divisions In Vitro
    Authors: M Girotra, V Trachsel, A Roch, MP Lutolf
    Int J Mol Sci, 2020-11-03;21(21):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  96. Marked Increased Production of Acute Phase Reactants by Skeletal Muscle during Cancer Cachexia
    Authors: IS Massart, G Paulissen, A Loumaye, P Lause, SA Pötgens, MM Thibaut, E Balan, L Deldicque, A Atfi, E Louis, D Gruson, LB Bindels, MA Meuwis, JP Thissen
    Cancers (Basel), 2020-10-31;12(11):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  97. The overexpression of TDP-43 in astrocytes causes neurodegeneration via a PTP1B-mediated inflammatory response
    Authors: S Lee, S Kim, HY Kang, HR Lim, Y Kwon, M Jo, YM Jeon, SR Kim, K Kim, CM Ha, S Lee, HJ Kim
    J Neuroinflammation, 2020-10-14;17(1):299.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  98. PPP2R2D suppresses interleukin-2 production and regulatory T cell function
    Authors: W Pan, A Sharabi, AP Ferretti, Y Zhang, C Burbano, N Yoshida, MG Tsokos, GC Tsokos
    JCI Insight, 2020-10-02;5(19):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  99. STX-0119, a novel STAT3 dimerization inhibitor, prevents fibrotic gene expression in a mouse model of kidney fibrosis by regulating Cxcr4 and Ccr1 expression
    Authors: K Makitani, N Ogo, A Asai
    Physiol Rep, 2020-10-01;8(20):e14627.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  100. Alternative Enhancer Usage and Targeted Polycomb Marking Hallmark Promoter Choice during T Cell Differentiation
    Authors: MA Maqbool, L Pioger, AZ El Aabidin, N Karasu, AM Molitor, LTM Dao, G Charbonnie, F van Laethe, R Fenouil, F Koch, G Lacaud, I Gut, M Gut, S Amigorena, O Joffre, T Sexton, S Spicuglia, JC Andrau
    Cell Rep, 2020-08-18;32(7):108048.
    Species: Human, Mouse
    Sample Types: Whole Cells
    Applications: Bioassay, Cell Culture
  101. Lactobacillus sakei suppresses collagen-induced arthritis and modulates the differentiation of T helper 17 cells and regulatory B cells
    Authors: J Jhun, HK Min, J Ryu, SY Lee, JG Ryu, JW Choi, HS Na, SY Lee, Y Jung, SJ Park, MS Park, B Kwon, GE Ji, ML Cho, SH Park
    J Transl Med, 2020-08-15;18(1):317.
    Species: Mouse
    Sample Types: Whole Tissue
  102. Extracellular vesicle-encapsulated IL-10 as novel nanotherapeutics against ischemic AKI
    Authors: TT Tang, B Wang, M Wu, ZL Li, Y Feng, JY Cao, D Yin, H Liu, RN Tang, SD Crowley, LL Lv, BC Liu
    Sci Adv, 2020-08-12;6(33):eaaz0748.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  103. N-Acetyldopamine derivatives from Periostracum Cicadae and their regulatory activities on Th1 and Th17 cell differentiation
    Authors: P Thapa, Y Gu, YS Kil, SC Baek, KH Kim, AR Han, EK Seo, H Choi, JH Chang, JW Nam
    Bioorg. Chem., 2020-07-14;102(0):104095.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  104. PPAR&beta/&delta-dependent MSC metabolism determines their immunoregulatory properties
    Authors: RA Contreras-, R Elizondo-V, MJ Torres, AM Vega-Lette, N Luque-Camp, MJ Paredes-Ma, C Pradenas, G Tejedor, K Oyarce, M Salgado, C Jorgensen, M Khoury, G Kronke, MA Garcia-Rob, C Altamirano, P Luz-Crawfo, F Djouad
    Sci Rep, 2020-07-10;10(1):11423.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  105. ADAM12 is a costimulatory molecule that determines Th1 cell fate and mediates tissue inflammation
    Authors: Y Liu, R Bockermann, M Hadi, I Safari, B Carrion, M Kveiborg, S Issazadeh-
    Cell. Mol. Immunol., 2020-06-22;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  106. CNTF-STAT3-IL-6 Axis Mediates Neuroinflammatory Cascade across Schwann Cell-Neuron-Microglia
    Authors: Z Hu, N Deng, K Liu, N Zhou, Y Sun, W Zeng
    Cell Rep, 2020-05-19;31(7):107657.
    Species: Mouse
    Sample Types:
    Applications: In Vivo
  107. Myeloid PTEN promotes chemotherapy-induced NLRP3-inflammasome activation and antitumour immunity
    Authors: Y Huang, H Wang, Y Hao, H Lin, M Dong, J Ye, L Song, Y Wang, Q Li, B Shan, Y Jiang, H Li, Z Shao, G Kroemer, H Zhang, L Bai, T Jin, C Wang, Y Ma, Y Cai, C Ding, S Liu, Y Pan, W Jiang, R Zhou
    Nat. Cell Biol., 2020-05-04;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  108. Developmental IL-6 Exposure Favors Production of PDGF-Responsive Multipotential Progenitors at the Expense of Neural Stem Cells and Other Progenitors
    Authors: E Kumari, FJ Velloso, A Nasuhidehn, A Somasundar, VH Savanur, KD Buono, SW Levison
    Stem Cell Reports, 2020-04-16;0(0):.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  109. Existence of reprogrammed lymphoma stem cells in a murine ALCL-like model
    Authors: S Kreutmair, C Klingeberg, T Poggio, G Andrieux, A Keller, C Miething, M Follo, D Pfeifer, K Shoumariye, C Lengerke, I Gonzalez-M, F Fend, R Zeiser, SD Turner, L Quintanill, M Boerries, J Duyster, AL Illert
    Leukemia, 2020-03-17;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  110. Extracellular CIRP induces macrophage endotoxin tolerance through IL-6R-mediated STAT3 activation
    Authors: M Zhou, M Aziz, NL Denning, HT Yen, G Ma, P Wang
    JCI Insight, 2020-03-12;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  111. Genetic basis for iMCD-TAFRO
    Authors: A Yoshimi, TM Trippett, N Zhang, X Chen, AV Penson, ME Arcila, J Pichardo, J Baik, A Sigler, H Harada, DC Fajgenbaum, A Dogan, O Abdel-Waha, W Xiao
    Oncogene, 2020-02-12;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  112. Periostin Promotes Colorectal Tumorigenesis through Integrin-FAK-Src Pathway-Mediated YAP/TAZ Activation
    Authors: H Ma, J Wang, X Zhao, T Wu, Z Huang, D Chen, Y Liu, G Ouyang
    Cell Rep, 2020-01-21;30(3):793-806.e6.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  113. Genetic Deletion of Socs3 in Smooth�Muscle Cells Ameliorates Aortic�Dissection in Mice
    Authors: S Hirakata, H Aoki, S Ohno-Urabe, M Nishihara, A Furusho, N Nishida, S Ito, M Hayashi, H Yasukawa, T Imaizumi, S Hiromatsu, H Tanaka, Y Fukumoto
    JACC Basic Transl Sci, 2020-01-08;5(2):126-144.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  114. Discrimination of Dormant and Active Hematopoietic Stem Cells by G0 Marker Reveals Dormancy Regulation by Cytoplasmic Calcium
    Authors: T Fukushima, Y Tanaka, FK Hamey, CH Chang, T Oki, S Asada, Y Hayashi, T Fujino, T Yonezawa, R Takeda, KC Kawabata, T Fukuyama, T Umemoto, K Takubo, H Takizawa, S Goyama, Y Ishihama, H Honda, B Göttgens, T Kitamura
    Cell Rep, 2019-12-17;29(12):4144-4158.e7.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  115. Integrated transcriptomic and epigenetic data analysis identifiesaberrant expression of genes in acute myeloid leukemia with MLL?AF9 translocation
    Authors: F Wang, Z Li, G Wang, X Tian, J Zhou, W Yu, Z Fan, L Dong, J Lu, J Xu, W Zhang, A Liang
    Mol Med Rep, 2019-11-26;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  116. Identification of a novel arthritis-associated osteoclast precursor macrophage regulated by FoxM1
    Authors: T Hasegawa, J Kikuta, T Sudo, Y Matsuura, T Matsui, S Simmons, K Ebina, M Hirao, D Okuzaki, Y Yoshida, A Hirao, VV Kalinichen, K Yamaoka, T Takeuchi, M Ishii
    Nat. Immunol., 2019-11-18;20(12):1631-1643.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  117. Batf Pioneers the Reorganization of Chromatin in Developing Effector T Cells via Ets1-Dependent Recruitment of Ctcf
    Authors: D Pham, CE Moseley, M Gao, D Savic, CJ Winstead, M Sun, BL Kee, RM Myers, CT Weaver, RD Hatton
    Cell Rep, 2019-10-29;29(5):1203-1220.e7.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  118. Tangeretin attenuates lipopolysaccharide-induced acute lung injury through Notch signaling pathway via suppressing Th17?cell response in mice
    Authors: M Li, Y Zhao, D Qi, J He, D Wang
    Microb. Pathog., 2019-10-29;138(0):103826.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  119. Suberoylanilide Hydroxamic Acid Attenuates Autoimmune Arthritis by Suppressing Th17 Cells through NR1D1 Inhibition
    Authors: DS Kim, HK Min, EK Kim, SC Yang, HS Na, SY Lee, JW Choi, KA Jung, SK Kwok, SH Park, ML Cho
    Mediators Inflamm., 2019-10-24;2019(0):5648987.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  120. Heterogeneity in old fibroblasts is linked to variability in reprogramming and wound healing
    Authors: S Mahmoudi, E Mancini, L Xu, A Moore, F Jahanbani, K Hebestreit, R Srinivasan, X Li, K Devarajan, L Prélot, CE Ang, Y Shibuya, BA Benayoun, ALS Chang, M Wernig, J Wysocka, MT Longaker, MP Snyder, A Brunet
    Nature, 2019-10-23;574(7779):553-558.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  121. Inhibition of Rho-Kinase Downregulates Th17 Cells and Ameliorates Hepatic Fibrosis by Schistosoma japonicum Infection
    Authors: W Zhou, Y Yang, C Mei, P Dong, S Mu, H Wu, Y Zhou, Y Zheng, F Guo, JQ Yang
    Cells, 2019-10-16;8(10):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  122. Serum amyloid A-mediated inflammasome activation of microglial cells in cerebral ischemia
    Authors: J Yu, H Zhu, S Taheri, W Mondy, L Bonilha, GS Magwood, D Lackland, RJ Adams, MS Kindy
    J. Neurosci., 2019-10-14;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
    Applications: ELISA Standard
  123. IL-12 signaling drives the differentiation and function of a TH1-derived TFH1-like cell population
    Authors: MD Powell, KA Read, BK Sreekumar, DM Jones, KJ Oestreich
    Sci Rep, 2019-09-30;9(1):13991.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  124. Lipocalin-2 (Lcn-2) Attenuates Polymicrobial Sepsis with LPS Preconditioning (LPS Tolerance) in FcGRIIb Deficient Lupus Mice
    Authors: T Ondee, J Gillen, P Visitchana, P Somparn, J Issara-Amp, C Dang Phi, W Chancharoe, D Gurusamy, A Nita-Lazar, A Leelahavan
    Cells, 2019-09-11;8(9):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  125. Ablation of RhoA impairs Th17 cell differentiation and alleviates house dust mite-triggered allergic airway inflammation
    Authors: JQ Yang, KW Kalim, Y Li, Y Zheng, F Guo
    J. Leukoc. Biol., 2019-07-01;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  126. 5,6,7,8-Tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidine derivatives as inhibitors of full-length RORγt
    Authors: C Lao, X Zhou, H Chen, F Wei, Z Huang, C Bai
    Bioorg. Chem., 2019-06-21;90(0):103077.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  127. 3?-Acetyloxy-oleanolic Acid Attenuates Pristane-Induced Lupus Nephritis by Regulating Th17 Differentiation
    Authors: X Zhou, H Chen, F Wei, Q Zhao, Q Su, J Liang, M Yin, X Tian, Z Liu, B Yu, C Bai, X He, Z Huang
    J Immunol Res, 2019-05-22;2019(0):2431617.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  128. Activation of aryl hydrocarbon receptor signaling by a novel agonist ameliorates autoimmune encephalomyelitis
    Authors: A Abdullah, M Maged, I Hairul-Isl, A Osama I, H Maha, A Manal, H Hamza
    PLoS ONE, 2019-04-26;14(4):e0215981.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  129. Baicalein ameliorates pristane-induced lupus nephritis via activating Nrf2/HO-1 in myeloid-derived suppressor cells
    Authors: D Li, G Shi, J Wang, D Zhang, Y Pan, H Dou, Y Hou
    Arthritis Res. Ther., 2019-04-25;21(1):105.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  130. Homoharringtonine exhibits potent anti-tumor effect and modulates DNA epigenome in acute myeloid leukemia by targeting SP1/TET1/5hmC
    Authors: C Li, L Dong, R Su, Y Bi, Y Qing, X Deng, Y Zhou, C Hu, M Yu, H Huang, X Jiang, X Li, X He, D Zou, C Shen, L Han, M Sun, J Skibbe, K Ferchen, X Qin, H Weng, H Huang, C Song, J Chen, J Jin
    Haematologica, 2019-04-11;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  131. IL-1 and TNF? Contribute to the Inflammatory Niche to Enhance Alveolar Regeneration
    Authors: H Katsura, Y Kobayashi, PR Tata, BLM Hogan
    Stem Cell Reports, 2019-03-28;0(0):.
    Species: Mouse
    Sample Types: Organoids
    Applications: Bioassay
  132. E0771 and 4T1 murine breast cancer cells and interleukin 6 alter gene expression patterns but do not induce browning in cultured white adipocytes
    Authors: JV Pearce, JS Farrar, JC Lownik, B Ni, S Chen, TW Kan, FS Celi
    Biochem Biophys Rep, 2019-03-20;18(0):100624.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  133. The Parkinson's disease-linked Leucine-rich repeat kinase 2 (LRRK2) is required for insulin-stimulated translocation of GLUT4
    Authors: N Funk, M Munz, T Ott, K Brockmann, A Wenninger-, R Kühn, D Vogt-Weise, F Giesert, W Wurst, T Gasser, S Biskup
    Sci Rep, 2019-03-14;9(1):4515.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  134. DGAT1 inhibits retinol-dependent regulatory T cell formation and mediates autoimmune encephalomyelitis
    Authors: KL Graham, BJ Werner, KM Moyer, AK Patton, CR Krois, HS Yoo, M Tverskoy, M LaJevic, JL Napoli, RA Sobel, BA Zabel, EC Butcher
    Proc. Natl. Acad. Sci. U.S.A., 2019-02-04;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  135. Satb1 regulates the effector program of encephalitogenic tissue Th17 cells in chronic inflammation
    Authors: K Yasuda, Y Kitagawa, R Kawakami, Y Isaka, H Watanabe, G Kondoh, T Kohwi-Shig, S Sakaguchi, K Hirota
    Nat Commun, 2019-02-01;10(1):549.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  136. Rps14, Csnk1a1 and miRNA145/miRNA146a deficiency cooperate in the clinical phenotype and activation of the innate immune system in the 5q- syndrome
    Authors: F Ribezzo, IAM Snoeren, S Ziegler, J Stoelben, PA Olofsen, A Henic, MV Ferreira, S Chen, USA Stalmann, G Buesche, RM Hoogenboez, R Kramann, U Platzbecke, MHGP Raaijmaker, BL Ebert, RK Schneider
    Leukemia, 2019-01-16;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  137. BTK signaling drives CD1dhiCD5+ regulatory B-cell differentiation to promote pancreatic carcinogenesis
    Authors: S Das, D Bar-Sagi
    Oncogene, 2019-01-11;0(0):.
    Species: Mouse
    Sample Types:
    Applications: Cell Culture
  138. Melanotan-II reverses autistic features in a maternal immune activation mouse model of autism
    Authors: E Minakova, J Lang, JS Medel-Matu, GG Gould, A Reynolds, D Shin, A Mazarati, R Sankar
    PLoS ONE, 2019-01-10;14(1):e0210389.
    Species: Mouse
    Sample Types: In Vivo
  139. REV-ERB? Regulates TH17 Cell Development and Autoimmunity
    Authors: M Amir, S Chaudhari, R Wang, S Campbell, SA Mosure, LB Chopp, Q Lu, J Shang, OB Pelletier, Y He, C Doebelin, MD Cameron, DJ Kojetin, TM Kamenecka, LA Solt
    Cell Rep, 2018-12-26;25(13):3733-3749.e8.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  140. Critical Adverse Impact of IL-6 in Acute Pneumovirus Infection
    Authors: CM Percopo, M Ma, TA Brenner, JO Krumholz, TJ Break, K Laky, HF Rosenberg
    J. Immunol., 2018-12-21;0(0):.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  141. Rab4b Deficiency in T Cells Promotes Adipose Treg/Th17 Imbalance, Adipose Tissue Dysfunction, and Insulin Resistance
    Authors: J Gilleron, G Bouget, S Ivanov, C Meziat, F Ceppo, B Vergoni, M Djedaini, A Soprani, K Dumas, A Jacquel, L Yvan-Charv, N Venteclef, JF Tanti, M Cormont
    Cell Rep, 2018-12-18;25(12):3329-3341.e5.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  142. EriB targeted inhibition of microglia activity attenuates MPP+ induced DA neuron injury through the NF-?B signaling pathway
    Authors: F Dou, X Chu, B Zhang, L Liang, G Lu, J Ding, S Chen
    Mol Brain, 2018-12-18;11(1):75.
    Species: Mouse
    Sample Types: Recombinant Protein
    Applications: ELISA (Standard)
  143. IL-23R Signaling Plays No Role in Myocardial Infarction
    Authors: E Engelowski, NF Modares, S Gorressen, P Bouvain, D Semmler, C Alter, Z Ding, U Flögel, J Schrader, H Xu, PA Lang, J Fischer, DM Floss, J Scheller
    Sci Rep, 2018-11-20;8(1):17078.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  144. TGF?1 signaling sustains aryl hydrocarbon receptor (AHR) expression and restrains the pathogenic potential of TH17 cells by an AHR-independent mechanism
    Authors: KA de Lima, PB Donate, J Talbot, M Davoli-Fer, RS Peres, TM Cunha, JC Alves-Filh, FQ Cunha
    Cell Death Dis, 2018-11-13;9(11):1130.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  145. Combined HDAC and BET Inhibition Enhances Melanoma Vaccine Immunogenicity and Efficacy
    Authors: A Badamchi-Z, KD Moynihan, RA Larocca, M Aid, NM Provine, MJ Iampietro, E Kinnear, P Penaloza-M, P Abbink, E Blass, JS Tregoning, DJ Irvine, DH Barouch
    J. Immunol., 2018-09-24;0(0):.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  146. GLK-IKK? signaling induces dimerization and translocation of the AhR-ROR?t complex in IL-17A induction and autoimmune disease
    Authors: HC Chuang, CY Tsai, CH Hsueh, TH Tan
    Sci Adv, 2018-09-12;4(9):eaat5401.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  147. Notch ligand Delta-like 4 induces epigenetic regulation of Treg cell differentiation and function in viral infection
    Authors: HA Ting, D de Almeida, AJ Rasky, CA Malinczak, IP Maillard, MA Schaller, NW Lukacs
    Mucosal Immunol, 2018-07-23;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  148. Administration of cytokine-induced myeloid-derived suppressor cells ameliorates renal fibrosis in diabetic mice
    Authors: CC Hsieh, CL Lin, JT He, M Chiang, Y Wang, YC Tsai, CH Hung, PJ Chang
    Stem Cell Res Ther, 2018-07-04;9(1):183.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  149. IL22 Inhibits Epithelial Stem Cell Expansion in an Ileal Organoid Model
    Authors: B Zwarycz, AD Gracz, KR Rivera, IA Williamson, LA Samsa, J Starmer, MA Daniele, L Salter-Cid, Q Zhao, ST Magness
    Cell Mol Gastroenterol Hepatol, 2018-07-04;7(1):1-17.
    Species: Mouse
    Sample Types: Organoids
    Applications: Bioassay
  150. Intraperitoneal infusion of mesenchymal stem cell attenuates severity of collagen antibody induced arthritis
    Authors: Y Nam, SM Jung, YA Rim, H Jung, K Lee, N Park, J Kim, Y Jang, YB Park, SH Park, JH Ju
    PLoS ONE, 2018-06-07;13(6):e0198740.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  151. Physiological culture conditions alter myotube morphology and responses to atrophy treatments: implications for in�vitro research on muscle wasting
    Authors: E Archer-Lah, C Lan, RT Jagoe
    Physiol Rep, 2018-06-01;6(12):e13726.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  152. Fank1 and Jazf1 promote multiciliated cell differentiation in the mouse airway epithelium
    Authors: JA Johnson, JK Watson, MZ Nikoli?, EL Rawlins
    Biol Open, 2018-04-16;7(4):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  153. A Nonpyroptotic IFN-?-Triggered Cell Death Mechanism in Nonphagocytic Cells Promotes Salmonella Clearance In Vivo
    Authors: JP Ingram, S Tursi, T Zhang, W Guo, C Yin, M A Wynosky-, J van der He, KQ Cai, M Yamamoto, BB Finlay, IE Brodsky, SI Grivenniko, Ç Tükel, S Balachandr
    J. Immunol., 2018-04-13;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  154. Expression of mutant Asxl1 perturbs hematopoiesis and promotes susceptibility to leukemic transformation
    Authors: R Nagase, D Inoue, A Pastore, T Fujino, HA Hou, N Yamasaki, S Goyama, M Saika, A Kanai, Y Sera, S Horikawa, Y Ota, S Asada, Y Hayashi, KC Kawabata, R Takeda, HF Tien, H Honda, O Abdel-Waha, T Kitamura
    J. Exp. Med., 2018-04-11;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  155. Fas Promotes T Helper 17 Cell Differentiation and Inhibits T Helper 1 Cell Development by Binding and Sequestering Transcription Factor STAT1
    Authors: G Meyer Zu H, D Przybylski, MA Schramm, C Wang, A Schnell, Y Lee, R Sobel, A Regev, VK Kuchroo
    Immunity, 2018-03-20;48(3):556-569.e7.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  156. In vivo selection with lentiviral expression of Bcl2T69A/S70A/S87Amutant in hematopoietic stem cell-transplanted mice
    Authors: YY Wang, S Ma, Q Chen, D Jiao, Y Yang
    Gene Ther., 2018-03-09;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  157. Hydrogen sulfide promotes immunomodulation of gingiva-derived mesenchymal stem cells via the Fas/FasL coupling pathway
    Authors: R Yang, T Yu, D Liu, S Shi, Y Zhou
    Stem Cell Res Ther, 2018-03-09;9(1):62.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  158. Enhanced insulin receptor, but not PI3K, signalling protects podocytes from ER stress
    Authors: KL Garner, VMS Betin, V Pinto, M Graham, E Abgueguen, M Barnes, DC Bedford, CA McArdle, RJM Coward
    Sci Rep, 2018-03-02;8(1):3902.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  159. Mesenchymal stem cells ameliorate experimental arthritis via expression of interleukin-1 receptor antagonist
    Authors: K Lee, N Park, H Jung, YA Rim, Y Nam, J Lee, SH Park, JH Ju
    PLoS ONE, 2018-02-26;13(2):e0193086.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  160. Celastrol mediates Th17 and Treg cell generation via metabolic signaling
    Authors: J Zhang, J Shan, X Chen, S Li, D Long, Y Li
    Biochem. Biophys. Res. Commun., 2018-02-21;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  161. Seizure progression and inflammatory mediators promote pericytosis and pericyte-microglia clustering at the cerebrovasculature
    Authors: W Klement, R Garbelli, E Zub, L Rossini, L Tassi, B Girard, M Blaquiere, F Bertaso, J Perroy, F de Bock, N Marchi
    Neurobiol. Dis., 2018-02-09;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  162. Hexokinase II may be dispensable for CD4 T cell responses against a virus infection
    Authors: SK Varanasi, U Jaggi, N Hay, BT Rouse
    PLoS ONE, 2018-01-19;13(1):e0191533.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  163. A novel prospective isolation of murine fetal liver progenitors to study in utero hematopoietic defects
    Authors: JE Draper, P Sroczynska, MZH Fadlullah, R Patel, G Newton, W Breitwiese, V Kouskoff, G Lacaud
    PLoS Genet., 2018-01-04;14(1):e1007127.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  164. Tumor-extrinsic discoidin domain receptor 1 promotes mammary tumor growth by regulatingadipose stromal interleukin 6 production in mice
    Authors: X Sun, K Gupta, B Wu, D Zhang, B Yuan, X Zhang, HC Chiang, C Zhang, TJ Curiel, MP Bendeck, S Hursting, Y Hu, R Li
    J. Biol. Chem., 2018-01-03;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  165. Inhibition of Poly(A)-binding protein with a synthetic RNA mimic reduces pain sensitization in mice
    Authors: P Barragán-I, TF Lou, VD Bhat, S Megat, MD Burton, TJ Price, ZT Campbell
    Nat Commun, 2018-01-02;9(1):10.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  166. Pharmacological Effect ofCaulophyllum robustumon Collagen-Induced Arthritis and Regulation of Nitric Oxide, NF-?B, and Proinflammatory Cytokines In Vivo and In Vitro
    Authors: QH Wang, SW Lv, YY Guo, JX Duan, SY Dong, QS Wang, FM Yu, H Su, HX Kuang
    Evid Based Complement Alternat Med, 2017-12-31;2017(0):8134321.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  167. Targeted inhibition of STAT/TET1 axis as a therapeutic strategy for acute myeloid leukemia
    Authors: X Jiang, C Hu, K Ferchen, J Nie, X Cui, CH Chen, L Cheng, Z Zuo, W Seibel, C He, Y Tang, JR Skibbe, M Wunderlich, WC Reinhold, L Dong, C Shen, S Arnovitz, B Ulrich, J Lu, H Weng, R Su, H Huang, Y Wang, C Li, X Qin, J Mulloy, Y Zheng, J Diao, J Jin, C Li, PP Liu, C He, Y Chen, J Chen
    Nat Commun, 2017-12-13;8(1):2099.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  168. Stromal Lkb1 deficiency leads to gastrointestinal tumorigenesis involving the IL-11-JAK/STAT3 pathway
    Authors: S Ollila, E Domènech-M, K Laajanen, IP Wong, S Tripathi, N Pentinmikk, Y Gao, Y Yan, EH Niemelä, TC Wang, B Viollet, G Leone, P Katajisto, K Vaahtomeri, TP Mäkelä
    J. Clin. Invest., 2017-12-04;0(0):.
    Species: Mouse
    Sample Types: Organoids
    Applications: Bioassay
  169. M�ller Cell-Derived PEDF Mediates Neuroprotection via STAT3 Activation
    Authors: W Eichler, H Savkovi?-C, S Bürger, M Beck, M Schmidt, P Wiedemann, A Reichenbac, JD Unterlauft
    Cell. Physiol. Biochem., 2017-11-30;44(4):1411-1424.
    Species: Mouse, Rat
    Sample Types: Whole Cells
    Applications: Bioassay
  170. Impact of combined sodium chloride and saturated long-chain fatty acid challenge on the differentiation of T helper cells in neuroinflammation
    Authors: A Hammer, A Schliep, S Jörg, A Haghikia, R Gold, M Kleinewiet, DN Müller, RA Linker
    J Neuroinflammation, 2017-09-12;14(1):184.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  171. Stat3 as a potential therapeutic target for rheumatoid arthritis
    Authors: T Oike, Y Sato, T Kobayashi, K Miyamoto, S Nakamura, Y Kaneko, S Kobayashi, K Harato, H Saya, M Matsumoto, M Nakamura, Y Niki, T Miyamoto
    Sci Rep, 2017-09-08;7(1):10965.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  172. Endothelium-derived extracellular vesicles promote splenic monocyte mobilization in myocardial infarction
    Authors: N Akbar, JE Digby, TJ Cahill, AN Tavare, AL Corbin, S Saluja, S Dawkins, L Edgar, N Rawlings, K Ziberna, E McNeill, E Johnson, AA Aljabali, RA Dragovic, M Rohling, TG Belgard, IA Udalova, DR Greaves, KM Channon, PR Riley, DC Anthony, RP Choudhury
    JCI Insight, 2017-09-07;2(17):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  173. Interferon-gamma regulates inflammatory cell death by targeting necroptosis in experimental autoimmune arthritis
    Authors: SH Lee, JY Kwon, SY Kim, K Jung, ML Cho
    Sci Rep, 2017-08-31;7(1):10133.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  174. Absence of Notch1 in murine myeloid cells attenuates the development of experimental autoimmune encephalomyelitis by affecting Th1 and Th17 priming
    Authors: M Fernández, EM Monsalve, S López-Lópe, A Ruiz-Garcí, S Mellado, E Caminos, JJ García-Ram, J Laborda, P Tranque, MJM Díaz-Guerr
    Eur. J. Immunol., 2017-08-31;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  175. IL-1? and IL-23 Promote Extrathymic Commitment of CD27(+)CD122(-) ?? T Cells to ??T17 Cells
    Authors: A Muschaweck, F Petermann, T Korn
    J. Immunol., 2017-08-30;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  176. Bone-induced expression of integrin ?3 enables targeted nanotherapy of breast cancer metastases
    Authors: MH Ross, AK Esser, GC Fox, AH Schmieder, X Yang, G Hu, D Pan, X Su, Y Xu, DV Novack, T Walsh, GA Colditz, GH Lukaszewic, E Cordell, JS Novack, JAJ Fitzpatric, DL Waning, KS Mohammad, TA Guise, GM Lanza, KN Weilbaeche
    Cancer Res., 2017-08-30;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  177. Integrated STAT3 and Ikaros Zinc Finger Transcription Factor Activities Regulate Bcl-6 Expression in CD4(+) Th Cells
    Authors: KA Read, MD Powell, CE Baker, BK Sreekumar, VM Ringel-Sca, H Bachus, RE Martin, ID Cooley, IC Allen, A Ballestero, KJ Oestreich
    J. Immunol., 2017-08-28;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  178. Lamtor1 Is Critically Required for CD4(+) T Cell Proliferation and Regulatory T Cell Suppressive Function
    Authors: T Hosokawa, T Kimura, S Nada, T Okuno, D Ito, S Kang, S Nojima, K Yamashita, T Nakatani, Y Hayama, Y Kato, Y Kinehara, M Nishide, N Mikami, S Koyama, H Takamatsu, D Okuzaki, N Ohkura, S Sakaguchi, M Okada, A Kumanogoh
    J. Immunol., 2017-08-02;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  179. BJ-2266 ameliorates experimental autoimmune encephalomyelitis through down-regulation of the JAK/STAT signaling pathway
    Authors: Z You, M Timilshina, BS Jeong, JH Chang
    Eur. J. Immunol., 2017-07-26;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  180. The Role of Inflammation in ?-cell Dedifferentiation
    Authors: TM Nordmann, E Dror, F Schulze, S Traub, E Berishvili, C Barbieux, M Böni-Schne, MY Donath
    Sci Rep, 2017-07-24;7(1):6285.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  181. The excretory-secretory products of Echinococcus granulosus protoscoleces directly regulate the differentiation of B10, B17 and Th17 cells
    Authors: W Pan, WT Hao, YJ Shen, XY Li, YJ Wang, FF Sun, JH Yin, J Zhang, RX Tang, JP Cao, KY Zheng
    Parasit Vectors, 2017-07-21;10(1):348.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  182. IL-23 restoration of Th17 effector function is independent of IL-6 and TGF-? in a mouse model of alcohol and burn injury
    Authors: X Li, AR Cannon, AM Hammer, NL Morris, MA Choudhry
    J. Leukoc. Biol., 2017-07-06;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  183. The MNK - eIF4E signaling axis contributes to injury-induced nociceptive plasticity and the development of chronic pain
    Authors: JK Moy, A Khoutorsky, MN Asiedu, BJ Black, JL Kuhn, P Barragán-I, S Megat, MD Burton, CC Burgos-Veg, OK Melemedjia, S Boitano, J Vagner, CG Gkogkas, JJ Pancrazio, JS Mogil, G Dussor, N Sonenberg, TJ Price
    J. Neurosci., 2017-07-03;0(0):.
    Species: Mouse
    Sample Types: In Vivo, Whole Cells
    Applications: Bioassay, In Vivo
  184. Interaction of reactive astrocytes with type I collagen induces astrocytic scar formation through the integrin-N-cadherin pathway after spinal cord injury
    Authors: M Hara, K Kobayakawa, Y Ohkawa, H Kumamaru, K Yokota, T Saito, K Kijima, S Yoshizaki, K Harimaya, Y Nakashima, S Okada
    Nat. Med., 2017-06-19;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  185. The frequency of Th17�cells in the small intestine exhibits a day-night variation dependent on circadian clock activity
    Authors: HP Thu Le, Y Nakamura, K Oh-Oka, K Ishimaru, S Nakajima, A Nakao
    Biochem. Biophys. Res. Commun., 2017-06-12;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  186. Selective Induction of Homeostatic Th17 Cells in the Murine Intestine by Cholera Toxin Interacting with the Microbiota
    Authors: Q Zhao, SN Harbour, R Kolde, IJ Latorre, HM Tun, TR Schoeb, H Turner, JJ Moon, E Khafipour, RJ Xavier, CT Weaver, CO Elson
    J. Immunol., 2017-05-24;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  187. Lentivector Iterations and Pre-Clinical Scale-Up/Toxicity Testing: Targeting Mobilized CD34(+) Cells for Correction of Fabry Disease
    Authors: J Huang, A Khan, BC Au, DL Barber, L López-Vásq, NL Prokopishy, M Boutin, M Rothe, JW Rip, M Abaoui, MS Nagree, S Dworski, A Schambach, A Keating, ML West, J Klassen, PV Turner, S Sirrs, CA Rupar, C Auray-Blai, R Foley, JA Medin
    Mol Ther Methods Clin Dev, 2017-05-12;5(0):241-258.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  188. Fibroblast Growth Factor 21 Deficiency Attenuates Experimental Colitis-Induced Adipose Tissue Lipolysis
    Authors: L Liu, C Zhao, Y Yang, X Kong, T Shao, L Ren, X Zhuang, B Yin, G Dryden, C McClain, W Luan, W Feng
    Gastroenterol Res Pract, 2017-05-11;2017(0):3089378.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  189. TNF? drives mitochondrial stress in POMC neurons in obesity
    Authors: CX Yi, M Walter, Y Gao, S Pitra, B Legutko, S Kälin, C Layritz, C García-Các, M Bielohuby, M Bidlingmai, SC Woods, A Ghanem, KK Conzelmann, JE Stern, M Jastroch, MH Tschöp
    Nat Commun, 2017-05-10;8(0):15143.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  190. Temporal and tissue-specific requirements for T-lymphocyte IL-6 signalling in obesity-associated inflammation and insulin resistance
    Authors: E Xu, MMA Pereira, I Karakasili, S Theurich, M Al-Maarri, G Rappl, A Waisman, FT Wunderlich, JC Brüning
    Nat Commun, 2017-05-03;8(0):14803.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  191. T-cell activation RhoGTPase-activating protein plays an important role in TH17-cell differentiation
    Authors: N Tamehiro, K Nishida, R Yanobu-Tak, M Goto, T Okamura, H Suzuki
    Immunol. Cell Biol., 2017-05-02;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  192. Induction of Colonic Regulatory T Cells by Mesalamine by Activating the Aryl Hydrocarbon Receptor
    Authors: K Oh-Oka, Y Kojima, K Uchida, K Yoda, K Ishimaru, S Nakajima, J Hemmi, H Kano, Y Fujii-Kuri, R Katoh, H Ito, A Nakao
    Cell Mol Gastroenterol Hepatol, 2017-04-11;4(1):135-151.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  193. Suppression of Th17 cell differentiation by misshapen/NIK-related kinase MINK1
    Authors: G Fu, Q Xu, Y Qiu, X Jin, T Xu, S Dong, J Wang, Y Ke, H Hu, X Cao, D Wang, H Cantor, X Gao, L Lu
    J. Exp. Med., 2017-04-11;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  194. IL-6 Improves Energy and Glucose Homeostasis in Obesity via Enhanced Central IL-6 trans-Signaling
    Authors: K Timper, JL Denson, SM Steculorum, C Heilinger, L Engström-R, CM Wunderlich, S Rose-John, FT Wunderlich, JC Brüning
    Cell Rep, 2017-04-11;19(2):267-280.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  195. Progenitor T-cell differentiation from hematopoietic stem cells using Delta-like-4 and VCAM-1
    Authors: S Shukla, MA Langley, J Singh, JM Edgar, M Mohtashami, JC Zúñiga-Pfl, PW Zandstra
    Nat. Methods, 2017-04-10;14(5):531-538.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  196. Monocytic and granulocytic myeloid derived suppressor cells differentially regulate spatiotemporal tumour plasticity during metastatic cascade
    Authors: M Ouzounova, E Lee, R Piranliogl, A El Andalou, R Kolhe, MF Demirci, D Marasco, I Asm, A Chadli, KA Hassan, M Thangaraju, G Zhou, AS Arbab, JK Cowell, H Korkaya
    Nat Commun, 2017-04-06;8(0):14979.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  197. mTORC2 controls Th9 polarization and allergic airway inflammation
    Authors: H Chen, L Zhang, P Wang, H Su, W Wang, Z Chu, L Zhang, X Zhang, Y Zhao
    Allergy, 2017-03-29;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  198. The mTOR signal regulates myeloid-derived suppressor cells differentiation and immunosuppressive function in acute kidney injury
    Authors: C Zhang, S Wang, J Li, W Zhang, L Zheng, C Yang, T Zhu, R Rong
    Cell Death Dis, 2017-03-23;8(3):e2695.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  199. Suppressive IL-17A(+)Foxp3(+) and ex-Th17 IL-17A(neg)Foxp3(+) Treg cells are a source of tumour-associated Treg cells
    Authors: S Downs-Cann, S Berkey, GM Delgoffe, RP Edwards, T Curiel, K Odunsi, DL Bartlett, N Obermajer
    Nat Commun, 2017-03-14;8(0):14649.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  200. BJ-1108, a 6-Amino-2,4,5-trimethylpyridin-3-ol analogue, regulates differentiation of Th1 and Th17 cells to ameliorate experimental autoimmune encephalomyelitis
    Authors: Y Kang, M Timilshina, TG Nam, BS Jeong, JH Chang
    Biol. Res, 2017-02-28;50(1):8.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  201. Inhibiting Oxidative Phosphorylation In Vivo Restrains Th17 Effector Responses and Ameliorates Murine Colitis
    Authors: L Franchi, I Monteleone, LY Hao, MA Spahr, W Zhao, X Liu, K Demock, A Kulkarni, CA Lesch, B Sanchez, L Carter, I Marafini, X Hu, O Mashadova, M Yuan, JM Asara, H Singh, CA Lyssiotis, G Monteleone, AW Opipari, GD Glick
    J. Immunol, 2017-02-27;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  202. Armc5 deletion causes developmental defects and compromises T-cell immune responses
    Authors: Y Hu, L Lao, J Mao, W Jin, H Luo, T Charpentie, S Qi, J Peng, B Hu, MM Marcinkiew, A Lamarre, J Wu
    Nat Commun, 2017-02-07;8(0):13834.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  203. Paeoniflorin Ameliorates Experimental Autoimmune Encephalomyelitis via Inhibition of Dendritic Cell Function and Th17 Cell Differentiation
    Authors: H Zhang, Y Qi, Y Yuan, L Cai, H Xu, L Zhang, B Su, H Nie
    Sci Rep, 2017-02-06;7(0):41887.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  204. Dendritic cell MST1 inhibits Th17 differentiation
    Authors: C Li, Y Bi, Y Li, H Yang, Q Yu, J Wang, Y Wang, H Su, A Jia, Y Hu, L Han, J Zhang, S Li, W Tao, G Liu
    Nat Commun, 2017-02-01;8(0):14275.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  205. Dual role of ALCAM in neuroinflammation and blood-brain barrier homeostasis
    Authors: MA L‚cuyer, O Saint-Laur, L BourbonniŠ, S Larouche, C Larochelle, L Michel, M Charabati, M Abadier, S Zandee, N Haghayegh, E Gowing, C Pittet, R Lyck, B Engelhardt, A Prat
    Proc. Natl. Acad. Sci. U.S.A, 2017-01-09;114(4):E524-E533.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  206. Ndfip1 restricts Th17 cell potency by limiting lineage stability and proinflammatory cytokine production
    Authors: AA Kesewa Lay, S L Sprout, D Phillips, PM Oliver
    Sci Rep, 2017-01-04;7(0):39649.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  207. Young microglia restore amyloid plaque clearance of aged microglia
    Authors: Anna Daria
    EMBO J, 2016-12-21;0(0):.
    Species: Mouse
    Sample Types: Complex Sample Type
    Applications: Bioassay
  208. Pharmacologic modulation of ROR?t translates to efficacy in preclinical and translational models of psoriasis and inflammatory arthritis
    Sci Rep, 2016-12-01;6(0):37977.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  209. P311 induces the transdifferentiation of epidermal stem cells to myofibroblast-like cells by stimulating transforming growth factor ?1 expression
    Stem Cell Res Ther, 2016-12-01;7(1):175.
    Species: Human, Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  210. Impaired Epidermal to Dendritic T Cell Signaling Slows Wound Repair in Aged Skin
    Authors: Elaine Fuchs
    Cell, 2016-11-17;167(5):1323-1338.e14.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  211. Activation of AMP-activated protein kinase rapidly suppresses multiple pro-inflammatory pathways in adipocytes including IL-1 receptor-associated kinase-4 phosphorylation
    Authors: Ian P Salt
    Mol. Cell. Endocrinol., 2016-11-11;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  212. The role of local IL6/JAK2/STAT3 signaling in high glucose-induced podocyte hypertrophy
    Kidney Res Clin Pract, 2016-09-17;35(4):212-218.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  213. Chronic myelogenous leukemia initiating cells require Polycomb group protein EZH2
    Cancer Discov, 2016-09-14;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  214. Lung epithelial tip progenitors integrate glucocorticoid- and STAT3-mediated signals to control progeny fate
    Authors: Emma L Rawlins
    Development, 2016-08-30;143(20):3686-3699.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Bioassay
  215. Murine iPSC-Derived Macrophages as a Tool for Disease Modeling of Hereditary Pulmonary Alveolar Proteinosis due to Csf2rb Deficiency
    Stem Cell Reports, 2016-07-21;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  216. Leptin directly promotes T-cell glycolytic metabolism to drive effector T-cell differentiation in a mouse model of autoimmunity
    Eur J Immunol, 2016-06-13;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  217. Enhanced immunoregulation of mesenchymal stem cells by IL-10-producing type 1 regulatory T cells in collagen-induced arthritis
    Authors: Jung-Yeon Lim
    Sci Rep, 2016-06-01;6(0):26851.
    Species: Mouse
    Sample Types: Cell Culture Supernates
    Applications: Bioassay
  218. Attenuation of PKR-like ER Kinase (PERK) Signaling Selectively Controls Endoplasmic Reticulum Stress-induced Inflammation Without Compromising Immunological Responses
    Authors: LN Guthrie, K Abiraman, ES Plyler, NT Sprenkle, SA Gibson, BC McFarland, R Rajbhandar, AL Rowse, EN Benveniste, GP Meares
    J. Biol. Chem., 2016-05-23;291(30):15830-40.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  219. T cells are necessary for ILC2 activation in house dust mite-induced allergic airway inflammation in mice
    Authors: BW Li, MJ de Bruijn, I Tindemans, M Lukkes, A KleinJan, HC Hoogsteden, RW Hendriks
    Eur J Immunol, 2016-05-12;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  220. Renalase expression by melanoma and tumor associated-macrophages promotes tumor growth through a STAT3-mediated mechanism
    Cancer Res, 2016-05-09;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  221. Modulation of splicing catalysis for therapeutic targeting of leukemia with mutations in genes encoding spliceosomal proteins
    Nat. Med., 2016-05-02;22(6):672-8.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  222. Phenotypic and Functional Plasticity of Murine Intestinal NKp46+ Group 3 Innate Lymphoid Cells
    J Immunol, 2016-04-22;196(11):4731-8.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  223. Alternative splicing of MALT1 controls signalling and activation of CD4(+) T cells
    Authors: I Meininger, RA Griesbach, D Hu, T Gehring, T Seeholzer, A Bertossi, J Kranich, A Oeckinghau, AC Eitelhuber, U Greczmiel, A Gewies, M Schmidt-Su, J Ruland, T Brocker, V Heissmeyer, F Heyd, D Krappmann
    Nat Commun, 2016-04-12;7(0):11292.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  224. Toll/Interleukin-1 Receptor Domain Derived from TcpC (TIR-TcpC) Ameliorates Experimental Autoimmune Arthritis by Down-modulating Th17 Cell Response
    Authors: Shweta Pasi
    J Biol Chem, 2016-03-28;291(23):12358-69.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  225. RGS10 deficiency ameliorates the severity of disease in experimental autoimmune encephalomyelitis.
    Authors: Lee J, Kannarkat G, Chung J, Joon Lee H, Graham K, Tansey M
    J Neuroinflammation, 2016-02-01;13(1):24.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  226. Negative regulation of the hepatic fibrogenic response by suppressor of cytokine signaling 1
    Cytokine, 2015-12-31;82(0):58-69.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  227. p(70S6K1) in the TORC1 pathway is essential for the differentiation of Th17 Cells, but not Th1, Th2, or Treg cells in mice.
    Authors: Sasaki C, Chen G, Munk R, Eitan E, Martindale J, Longo D, Ghosh P
    Eur J Immunol, 2015-11-19;46(1):212-22.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  228. Mouse Resistin (mRetn): cloning, expression and purification in Escherichia coli and the potential regulative effects on murine bone marrow hematopoiesis.
    Authors: Wang F, Gao J, Malisani A, Xi X, Han W, Wan X
    BMC Biotechnol, 2015-11-16;15(0):105.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  229. Identification of Tetraazacyclic Compounds as Novel Potent Inhibitors Antagonizing RORgammat Activity and Suppressing Th17 Cell Differentiation.
    Authors: Ding Q, Zhao M, Yu B, Bai C, Huang Z
    PLoS ONE, 2015-09-14;10(9):e0137711.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  230. A Key Role for Leukemia Inhibitory Factor in C26 Cancer Cachexia.
    Authors: Seto D, Kandarian S, Jackman R
    J Biol Chem, 2015-06-19;290(32):19976-86.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  231. Autocrine amplification of immature myeloid cells by IL-6 in multiple myeloma-infiltrated bone marrow.
    Authors: Matthes T, Manfroi B, Zeller A, Dunand-Sauthier I, Bogen B, Huard B
    Leukemia, 2015-06-19;29(9):1882-90.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  232. Interleukin-6 Stimulates Defective Angiogenesis.
    Authors: Gopinathan G, Milagre C, Pearce O, Reynolds L, Hodivala-Dilke K, Leinster D, Zhong H, Hollingsworth R, Thompson R, Whiteford J, Balkwill F
    Cancer Res, 2015-06-16;75(15):3098-107.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Bioassay
  233. Mesenchymal stem/stromal cells protect against autoimmunity via CCL2-dependent recruitment of myeloid-derived suppressor cells.
    Authors: Lee H, Ko J, Jeong H, Ko A, Kim M, Wee W, Yoon S, Oh J
    J Immunol, 2015-03-13;194(8):3634-45.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  234. KIM-1-mediated phagocytosis reduces acute injury to the kidney.
    Authors: Yang L, Brooks C, Xiao S, Sabbisetti V, Yeung M, Hsiao L, Ichimura T, Kuchroo V, Bonventre J
    J Clin Invest, 2015-03-09;125(4):1620-36.
    Species: Mouse
    Sample Types: Cell Lysates
    Applications: ELISA (Standard)
  235. IkappaBNS regulates murine Th17 differentiation during gut inflammation and infection.
    Authors: Annemann M, Wang Z, Plaza-Sirvent C, Glauben R, Schuster M, Ewald Sander F, Mamareli P, Kuhl A, Siegmund B, Lochner M, Schmitz I
    J Immunol, 2015-02-18;194(6):2888-98.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  236. Identification of modulators of the nuclear receptor peroxisome proliferator-activated receptor alpha (PPARalpha) in a mouse liver gene expression compendium.
    Authors: Oshida K, Vasani N, Thomas R, Applegate D, Rosen M, Abbott B, Lau C, Guo G, Aleksunes L, Klaassen C, Corton J
    PLoS ONE, 2015-02-17;10(2):e0112655.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  237. CXCL13 antibody for the treatment of autoimmune disorders.
    Authors: Klimatcheva E, Pandina T, Reilly C, Torno S, Bussler H, Scrivens M, Jonason A, Mallow C, Doherty M, Paris M, Smith E, Zauderer M
    BMC Immunol, 2015-02-12;16(0):6.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  238. Testosterone suppresses hepatic inflammation by the downregulation of IL-17, CXCL-9, and CXCL-10 in a mouse model of experimental acute cholangitis.
    Authors: Schwinge D, Carambia A, Quaas A, Krech T, Wegscheid C, Tiegs G, Prinz I, Lohse A, Herkel J, Schramm C
    J Immunol, 2015-02-11;194(6):2522-30.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  239. IL-1 signaling modulates activation of STAT transcription factors to antagonize retinoic acid signaling and control the TH17 cell-iTreg cell balance.
    Authors: Basu R, Whitley S, Bhaumik S, Zindl C, Schoeb T, Benveniste E, Pear W, Hatton R, Weaver C
    Nat Immunol, 2015-02-02;16(3):286-95.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  240. Immune requirements for protective Th17 recall responses to Mycobacterium tuberculosis challenge.
    Authors: Monin L, Griffiths K, Slight S, Lin Y, Rangel-Moreno J, Khader S
    Mucosal Immunol, 2015-01-28;8(5):1099-109.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  241. Coexistent ARID1A-PIK3CA mutations promote ovarian clear-cell tumorigenesis through pro-tumorigenic inflammatory cytokine signalling.
    Authors: Chandler, Ronald L, Damrauer, Jeffrey, Raab, Jesse R, Schisler, Jonathan, Wilkerson, Matthew, Didion, John P, Starmer, Joshua, Serber, Daniel, Yee, Della, Xiong, Jessie, Darr, David B, Pardo-Manuel de Villena, Fernando, Kim, William, Magnuson, Terry
    Nat Commun, 2015-01-27;6(0):6118.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  242. miR-148a is upregulated by Twist1 and T-bet and promotes Th1-cell survival by regulating the proapoptotic gene Bim.
    Authors: Haftmann C, Stittrich A, Zimmermann J, Fang Z, Hradilkova K, Bardua M, Westendorf K, Heinz G, Riedel R, Siede J, Lehmann K, Weinberger E, Zimmel D, Lauer U, Haupl T, Sieper J, Backhaus M, Neumann C, Hoffmann U, Porstner M, Chen W, Grun J, Baumgrass R, Matz M, Lohning M, Scheffold A, Wittmann J, Chang H, Rajewsky N, Jack H, Radbruch A, Mashreghi M
    Eur J Immunol, 2015-01-22;45(4):1192-205.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  243. ShcA regulates late stages of T cell development and peripheral CD4+ T cell numbers.
    Authors: Buckley M, Trampont P, Arandjelovic S, Fond A, Juncadella I, Ravichandran K
    J Immunol, 2015-01-16;194(4):1665-76.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  244. ROR inverse agonist suppresses insulitis and prevents hyperglycemia in a mouse model of type 1 diabetes.
    Authors: Solt L, Banerjee S, Campbell S, Kamenecka T, Burris T
    Endocrinology, 2015-01-05;156(3):869-81.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  245. Suppression of Th1-mediated autoimmunity by embryonic stem cell-derived dendritic cells.
    Authors: Ikeda T, Hirata S, Takamatsu K, Haruta M, Tsukamoto H, Ito T, Uchino M, Ando Y, Nagafuchi S, Nishimura Y, Senju S
    PLoS ONE, 2014-12-18;9(12):e115198.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  246. Deubiquitinase DUBA is a post-translational brake on interleukin-17 production in T cells.
    Authors: Rutz S, Kayagaki N, Phung Q, Eidenschenk C, Noubade R, Wang X, Lesch J, Lu R, Newton K, Huang O, Cochran A, Vasser M, Fauber B, DeVoss J, Webster J, Diehl L, Modrusan Z, Kirkpatrick D, Lill J, Ouyang W, Dixit V
    Nature, 2014-12-03;518(7539):417-21.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  247. T-cell-restricted T-bet overexpression induces aberrant hematopoiesis of myeloid cells and impairs function of macrophages in the lung.
    Authors: Iriguchi S, Kikuchi N, Kaneko S, Noguchi E, Morishima Y, Matsuyama M, Yoh K, Takahashi S, Nakauchi H, Ishii Y
    Blood, 2014-10-27;125(2):370-82.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  248. Grb10 is involved in BCR-ABL-positive leukemia in mice.
    Authors: Illert, A L, Albers, C, Kreutmair, S, Leischner, H, Peschel, C, Miething, C, Duyster, J
    Leukemia, 2014-09-24;29(4):858-68.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Bioassay
  249. Unexpected phenotype of mice lacking Shcbp1, a protein induced during T cell proliferation.
    Authors: Buckley M, Arandjelovic S, Trampont P, Kim T, Braciale T, Ravichandran K
    PLoS ONE, 2014-08-25;9(8):e105576.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  250. IL-6/STAT3 promotes regeneration of airway ciliated cells from basal stem cells.
    Authors: Tadokoro, Tomomi, Wang, Yang, Barak, Larry S, Bai, Yushi, Randell, Scott H, Hogan, Brigid L
    Proc Natl Acad Sci U S A, 2014-08-18;111(35):E3641-9.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  251. Role of TGF-beta signaling in generation of CD39+CD73+ myeloid cells in tumors.
    Authors: Ryzhov S, Pickup M, Chytil A, Gorska A, Zhang Q, Owens P, Feoktistov I, Moses H, Novitskiy S
    J Immunol, 2014-08-15;193(6):3155-64.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  252. The DNA binding property of PML/RARA but not the integrity of PML nuclear bodies is indispensable for leukemic transformation.
    Authors: Liu X, Yuan H, Peres L, Chen S, Chen Z, de The H, Zhou J, Zhu J
    PLoS ONE, 2014-08-13;9(8):e104906.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  253. PERK-dependent activation of JAK1 and STAT3 contributes to endoplasmic reticulum stress-induced inflammation.
    Authors: Meares G, Liu Y, Rajbhandari R, Qin H, Nozell S, Mobley J, Corbett J, Benveniste E
    Mol Cell Biol, 2014-08-11;34(20):3911-25.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  254. TGF-beta signaling initiated in dendritic cells instructs suppressive effects on Th17 differentiation at the site of neuroinflammation.
    Authors: Speck S, Lim J, Shelake S, Matka M, Stoddard J, Farr A, Kuchroo V, Laouar Y
    PLoS ONE, 2014-07-29;9(7):e102390.
    Species: Mouse
    Sample Types: Cell Culture Supernates
    Applications: ELISA (Standard)
  255. Role of Blimp-1 in programing Th effector cells into IL-10 producers.
    Authors: Neumann C, Heinrich F, Neumann K, Junghans V, Mashreghi M, Ahlers J, Janke M, Rudolph C, Mockel-Tenbrinck N, Kuhl A, Heimesaat M, Esser C, Im S, Radbruch A, Rutz S, Scheffold A
    J Exp Med, 2014-07-29;211(9):1807-19.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  256. Glimepiride reduces CD14 expression and cytokine secretion from macrophages.
    Authors: Ingham V, Williams A, Bate C
    J Neuroinflammation, 2014-06-21;11(0):115.
    Species: Mouse
    Sample Types: Cell Culture Supernates
    Applications: ELISA (Standard)
  257. Increased IL-6 expression in osteoclasts is necessary but not sufficient for the development of Paget's disease of bone.
    Authors: Teramachi J, Zhou H, Subler M, Kitagawa Y, Galson D, Dempster D, Windle J, Kurihara N, Roodman G
    J Bone Miner Res, 2014-06-01;29(6):1456-65.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  258. miR-20b suppresses Th17 differentiation and the pathogenesis of experimental autoimmune encephalomyelitis by targeting RORgammat and STAT3.
    Authors: Zhu E, Wang X, Zheng B, Wang Q, Hao J, Chen S, Zhao Q, Zhao L, Wu Z, Yin Z
    J Immunol, 2014-05-19;192(12):5599-609.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  259. Hes1 promotes blast crisis in chronic myelogenous leukemia through MMP-9 upregulation in leukemic cells.
    Authors: Nakahara F, Kitaura J, Uchida T, Nishida C, Togami K, Inoue D, Matsukawa T, Kagiyama Y, Enomoto Y, Kawabata K, Chen-Yi L, Komeno Y, Izawa K, Oki T, Nagae G, Harada Y, Harada H, Otsu M, Aburatani H, Heissig B, Hattori K, Kitamura T
    Blood, 2014-05-13;123(25):3932-42.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  260. Elongated TCR alpha chain CDR3 favors an altered CD4 cytokine profile.
    Authors: Reynolds C, Chong D, Raynsford E, Quigley K, Kelly D, Llewellyn-Hughes J, Altmann D, Boyton R
    BMC Biol, 2014-05-09;12(0):32.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  261. IL-21 induces IL-22 production in CD4+ T cells.
    Authors: Yeste A, Mascanfroni I, Nadeau M, Burns E, Tukpah A, Santiago A, Wu C, Patel B, Kumar D, Quintana F
    Nat Commun, 2014-05-06;5(0):3753.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  262. Macrophage-inducing FasL on chondrocytes forms immune privilege in cartilage tissue engineering, enhancing in vivo regeneration.
    Authors: Fujihara Y, Takato T, Hoshi K
    Stem Cells, 2014-05-01;32(5):1208-19.
    Species: Human, Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  263. Attenuation of experimental colitis in glutathione peroxidase 1 and catalase double knockout mice through enhancing regulatory T cell function.
    Authors: Kim H, Lee A, Choi E, Kie J, Lim W, Lee H, Moon B, Seoh J
    PLoS ONE, 2014-04-17;9(4):e95332.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  264. M2 kupffer cells promote hepatocyte senescence: an IL-6-dependent protective mechanism against alcoholic liver disease.
    Authors: Wan J, Benkdane M, Alons E, Lotersztajn S, Pavoine C
    Am J Pathol, 2014-04-05;184(6):1763-72.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  265. Signaling by IL-6 promotes alternative activation of macrophages to limit endotoxemia and obesity-associated resistance to insulin.
    Authors: Mauer J, Chaurasia B, Goldau J, Vogt M, Ruud J, Nguyen K, Theurich S, Hausen A, Schmitz J, Bronneke H, Estevez E, Allen T, Mesaros A, Partridge L, Febbraio M, Chawla A, Wunderlich F, Bruning J
    Nat Immunol, 2014-03-30;15(5):423-30.
    Species: Mouse
    Sample Types: In Vivo, Whole Cells
    Applications: Bioassay, In Vivo
  266. Proinflammatory cytokines differentially regulate adipocyte mitochondrial metabolism, oxidative stress, and dynamics.
    Authors: Hahn W, Kuzmicic J, Burrill J, Donoghue M, Foncea R, Jensen M, Lavandero S, Arriaga E, Bernlohr D
    Am J Physiol Endocrinol Metab, 2014-03-04;306(9):E1033-45.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  267. Netrin-1 promotes adipose tissue macrophage retention and insulin resistance in obesity.
    Authors: Ramkhelawon B, Hennessy E, Menager M, Ray T, Sheedy F, Hutchison S, Wanschel A, Oldebeken S, Geoffrion M, Spiro W, Miller G, McPherson R, Rayner K, Moore K
    Nat Med, 2014-03-02;20(4):377-84.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  268. TGFbeta-mediated suppression of CD248 in non-cancer cells via canonical Smad-dependent signaling pathways is uncoupled in cancer cells.
    Authors: Suresh Babu S, Valdez Y, Xu A, O'Byrne A, Calvo F, Lei V, Conway E
    BMC Cancer, 2014-02-20;14(0):113.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  269. Unique macrophages different from M1/M2 macrophages inhibit T cell mitogenesis while upregulating Th17 polarization.
    Authors: Tatano Y, Shimizu T, Tomioka H
    Sci Rep, 2014-02-20;4(0):4146.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  270. Gene therapy delivery of myelin oligodendrocyte glycoprotein (MOG) via hematopoietic stem cell transfer induces MOG-specific B cell deletion.
    Authors: Chung, Jie-Yu, Figgett, William, Fairfax, Kirsten, Bernard, Claude, Chan, James, Toh, Ban-Hock, Mackay, Fabienne, Alderuccio, Frank
    J Immunol, 2014-02-14;192(6):2593-601.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  271. The type I BMP receptor Alk3 is required for the induction of hepatic hepcidin gene expression by interleukin-6.
    Authors: Mayeur, Claire, Lohmeyer, Lisa K, Leyton, Patricio, Kao, Sonya M, Pappas, Alexandr, Kolodziej, Starsha, Spagnolli, Ester, Yu, Binglan, Galdos, Rita L, Yu, Paul B, Peterson, Randall, Bloch, Donald B, Bloch, Kenneth, Steinbicker, Andrea U
    Blood, 2014-02-05;123(14):2261-8.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  272. Chemically modified DNA aptamers bind interleukin-6 with high affinity and inhibit signaling by blocking its interaction with interleukin-6 receptor.
    Authors: Gupta, Shashi, Hirota, Masao, Waugh, Sheela M, Murakami, Ikuo, Suzuki, Tomoki, Muraguchi, Masahiro, Shibamori, Masafumi, Ishikawa, Yuichi, Jarvis, Thale C, Carter, Jeffrey, Zhang, Chi, Gawande, Bharat, Vrkljan, Michael, Janjic, Nebojsa, Schneider, Daniel J
    J Biol Chem, 2014-01-12;289(12):8706-19.
    Applications: Bioassay
  273. Dual-specificity phosphatase 14 (DUSP14/MKP6) negatively regulates TCR signaling by inhibiting TAB1 activation.
    Authors: Yang C, Li J, Chiu L, Lan J, Chen D, Chuang H, Huang C, Tan T
    J Immunol, 2014-01-08;192(4):1547-57.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  274. Role of IL-6 in exercise training- and cold-induced UCP1 expression in subcutaneous white adipose tissue.
    Authors: Knudsen J, Murholm M, Carey A, Bienso R, Basse A, Allen T, Hidalgo J, Kingwell B, Febbraio M, Hansen J, Pilegaard H
    PLoS ONE, 2014-01-08;9(1):e84910.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  275. To investigate the necessity of STRA6 upregulation in T cells during T cell immune responses.
    Authors: Terra R, Wang X, Hu Y, Charpentier T, Lamarre A, Zhong M, Sun H, Mao J, Qi S, Luo H, Wu J
    PLoS ONE, 2013-12-31;8(12):e82808.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  276. Inflammation regulates TMPRSS6 expression via STAT5.
    Authors: Meynard, Delphine, Sun, Chia Chi, Wu, Qifang, Chen, Wenjie, Chen, Shanzhuo, Nelson, Caroline, Waters, Michael, Babitt, Jodie L, Lin, Herbert
    PLoS ONE, 2013-12-23;8(12):e82127.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  277. Altered inactivation of commensal LPS due to acyloxyacyl hydrolase deficiency in colonic dendritic cells impairs mucosal Th17 immunity.
    Authors: Janelsins, Brian M, Lu, Mingfang, Datta, Sandip K
    Proc Natl Acad Sci U S A, 2013-12-16;111(1):373-8.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  278. Exposure to atmospheric particulate matter enhances Th17 polarization through the aryl hydrocarbon receptor.
    Authors: van Voorhis, Michael, Knopp, Samantha, Julliard, Walker, Fechner, John H, Zhang, Xiaoji, Schauer, James J, Mezrich, Joshua D
    PLoS ONE, 2013-12-11;8(12):e82545.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  279. Therapeutic efficacy of suppressing the Jak/STAT pathway in multiple models of experimental autoimmune encephalomyelitis.
    Authors: Liu Y, Holdbrooks A, De Sarno P, Rowse A, Yanagisawa L, McFarland B, Harrington L, Raman C, Sabbaj S, Benveniste E, Qin H
    J Immunol, 2013-12-09;192(1):59-72.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  280. Acteoside suppresses RANKL-mediated osteoclastogenesis by inhibiting c-Fos induction and NF-kappaB pathway and attenuating ROS production.
    Authors: Lee S, Lee K, Yi S, Kook S, Lee J
    PLoS ONE, 2013-12-04;8(12):e80873.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  281. Identification of transcription factors for lineage-specific ESC differentiation.
    Authors: Yamamizu K, Piao Y, Sharov A, Zsiros V, Yu H, Nakazawa K, Schlessinger D, Ko M
    Stem Cell Reports, 2013-11-27;1(6):545-59.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  282. MicroRNA-132 suppresses autoimmune encephalomyelitis by inducing cholinergic anti-inflammation: a new Ahr-based exploration.
    Authors: Hanieh H, Alzahrani A
    Eur J Immunol, 2013-10-01;43(10):2771-82.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  283. IL-27 acts on DCs to suppress the T cell response and autoimmunity by inducing expression of the immunoregulatory molecule CD39.
    Authors: Mascanfroni, Ivan D, Yeste, Ada, Vieira, Silvio M, Burns, Evan J, Patel, Bonny, Sloma, Ido, Wu, Yan, Mayo, Lior, Ben-Hamo, Rotem, Efroni, Sol, Kuchroo, Vijay K, Robson, Simon C, Quintana, Francisc
    Nat Immunol, 2013-09-01;14(10):1054-63.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  284. Induction of a hemogenic program in mouse fibroblasts.
    Authors: Pereira C, Chang B, Qiu J, Niu X, Papatsenko D, Hendry C, Clark N, Nomura-Kitabayashi A, Kovacic J, Ma'ayan A, Schaniel C, Lemischka I, Moore K
    Cell Stem Cell, 2013-06-13;13(2):205-18.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  285. Kynurenine 3-monooxygenase mediates inhibition of Th17 differentiation via catabolism of endogenous aryl hydrocarbon receptor ligands.
    Authors: Stephens G, Wang Q, Swerdlow B, Bhat G, Kolbeck R, Fung M
    Eur J Immunol, 2013-05-08;43(7):1727-34.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  286. T helper type 17 cells contribute to anti-tumour immunity and promote the recruitment of T helper type 1 cells to the tumour.
    Authors: Nunez S, Saez J, Fernandez D, Flores-Santibanez F, Alvarez K, Tejon G, Ruiz P, Maldonado P, Hidalgo Y, Manriquez V, Bono M, Rosemblatt M, Sauma D
    Immunology, 2013-05-01;139(1):61-71.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  287. Regulatory B cells suppress imiquimod-induced, psoriasis-like skin inflammation.
    Authors: Yanaba K, Kamata M, Ishiura N, Shibata S, Asano Y, Tada Y, Sugaya M, Kadono T, Tedder T, Sato S
    J Leukoc Biol, 2013-04-29;94(4):563-73.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  288. Interferon gamma suppresses collagen-induced arthritis by regulation of Th17 through the induction of indoleamine-2,3-deoxygenase.
    Authors: Lee J, Lee J, Park M, Lim M, Park E, Kim E, Yang E, Lee S, Jhun J, Park S, Kim H, Cho M
    PLoS ONE, 2013-04-16;8(4):e60900.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  289. PI3-kinase gamma promotes Rap1a-mediated activation of myeloid cell integrin alpha4beta1, leading to tumor inflammation and growth.
    Authors: Schmid M, Franco I, Kang S, Hirsch E, Quilliam L, Varner J
    PLoS ONE, 2013-04-02;8(4):e60226.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  290. p53 controls autoimmune arthritis via STAT-mediated regulation of the Th17 cell/Treg cell balance in mice.
    Authors: Park J, Lim M, Cho M, Ryu J, Moon Y, Jhun J, Byun J, Kim E, Hwang S, Ju J, Kwok S, Kim H
    Arthritis Rheum, 2013-04-01;65(4):949-59.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  291. Myeloid-derived suppressor cells regulate growth of multiple myeloma by inhibiting T cells in bone marrow.
    Authors: Ramachandran, Indu R, Martner, Anna, Pisklakova, Alexandr, Condamine, Thomas, Chase, Tess, Vogl, Thomas, Roth, Johannes, Gabrilovich, Dmitry, Nefedova, Yulia
    J Immunol, 2013-03-04;190(7):3815-23.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  292. Innate Stat3-mediated induction of the antimicrobial protein Reg3gamma is required for host defense against MRSA pneumonia.
    Authors: Choi S, McAleer J, Zheng M, Pociask D, Kaplan M, Qin S, Reinhart T, Kolls J
    J Exp Med, 2013-02-11;210(3):551-61.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  293. CDK8 kinase phosphorylates transcription factor STAT1 to selectively regulate the interferon response.
    Authors: Bancerek J, Poss Z, Steinparzer I, Sedlyarov V, Pfaffenwimmer T, Mikulic I, Dolken L, Strobl B, Muller M, Taatjes D, Kovarik P
    Immunity, 2013-01-24;38(2):250-62.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  294. The soluble interleukin-6 receptor is a mediator of hematopoietic and skeletal actions of parathyroid hormone.
    Authors: Cho S, Pirih F, Koh A, Michalski M, Eber M, Ritchie K, Sinder B, Oh S, Al-Dujaili S, Lee J, Kozloff K, Danciu T, Wronski T, McCauley L
    J Biol Chem, 2013-01-07;288(10):6814-25.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  295. Chemotherapy-triggered cathepsin B release in myeloid-derived suppressor cells activates the Nlrp3 inflammasome and promotes tumor growth.
    Authors: Bruchard M, Mignot G, Derangere V, Chalmin F, Chevriaux A, Vegran F, Boireau W, Simon B, Ryffel B, Connat J, Kanellopoulos J, Martin F, Rebe C, Apetoh L, Ghiringhelli F
    Nat Med, 2012-12-02;19(1):57-64.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  296. Interleukin 7 (IL-7) selectively promotes mouse and human IL-17-producing gammadelta cells.
    Authors: Michel M, Pang D, Haque S, Potocnik A, Pennington D, Hayday A
    Proc Natl Acad Sci U S A, 2012-10-09;109(43):17549-54.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  297. IL-6 activates STAT5 in T cells.
    Authors: Tormo AJ, Letellier MC, Sharma M, Elson G, Crabe S, Gauchat JF
    Cytokine, 2012-07-31;60(0):575.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  298. Robust tumor immunity to melanoma mediated by interleukin-9-producing T cells.
    Nat. Med., 2012-07-08;1248(0):18.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  299. Regulation of innate CD8+ T-cell activation mediated by cytokines.
    Proc Natl Acad Sci U S A, 2012-06-04;109(25):9971-6.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  300. Sphingosine-1-phosphate enhances satellite cell activation in dystrophic muscles through a S1PR2/STAT3 signaling pathway.
    Authors: Loh KC, Leong WI, Carlson ME
    PLoS ONE, 2012-05-14;7(5):e37218.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  301. Hepatocyte-specific mutation of both NF-kappaB RelA and STAT3 abrogates the acute phase response in mice.
    Authors: Quinton LJ, Blahna MT, Jones MR, Allen E, Ferrari JD, Hilliard KL, Zhang X, Sabharwal V, Algul H, Akira S, Schmid RM, Pelton SI, Spira A, Mizgerd JP
    J. Clin. Invest., 2012-04-02;122(5):1758-63.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  302. Hepatocarcinogenesis in FXR-/- mice mimics human HCC progression that operates through HNF1alpha regulation of FXR expression.
    Authors: Liu N, Meng Z, Lou G, Zhou W, Wang X, Zhang Y, Zhang L, Liu X, Yen Y, Lai L, Forman BM, Xu Z, Xu R, Huang W
    Mol. Endocrinol., 2012-04-02;26(5):775-85.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  303. CXCL1 can be regulated by IL-6 and promotes granulocyte adhesion to brain capillaries during bacterial toxin exposure and encephalomyelitis.
    Authors: Roy M, Richard JF, Dumas A, Vallieres L
    J Neuroinflammation, 2012-01-23;9(0):18.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  304. The effect of conditional EFNB1 deletion in the T cell compartment on T cell development and function.
    Authors: Jin W, Qi S, Luo H
    BMC Immunol., 2011-12-19;12(0):68.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  305. Host-derived MCP-1 and MIP-1alpha regulate protective anti-tumor immunity to localized and metastatic B16 melanoma.
    Authors: Nakasone Y, Fujimoto M, Matsushita T, Hamaguchi Y, Huu DL, Yanaba M, Sato S, Takehara K, Hasegawa M
    Am. J. Pathol., 2011-10-26;180(1):365-74.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  306. Leukemia inhibitory factor inhibits T helper 17 cell differentiation and confers treatment effects of neural progenitor cell therapy in autoimmune disease.
    Authors: Cao W, Yang Y, Wang Z, Liu A, Fang L, Wu F, Hong J, Shi Y, Leung S, Dong C, Zhang JZ
    Immunity, 2011-08-11;35(2):273-84.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  307. Aryl hydrocarbon receptor deficiency in T cells suppresses the development of collagen-induced arthritis.
    Authors: Nakahama T, Kimura A, Nguyen NT, Chinen I, Hanieh H, Nohara K, Fujii-Kuriyama Y, Kishimoto T
    Proc. Natl. Acad. Sci. U.S.A., 2011-08-08;108(34):14222-7.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  308. The encephalitogenicity of T(H)17 cells is dependent on IL-1- and IL-23-induced production of the cytokine GM-CSF.
    Authors: El-Behi M, Ciric B, Dai H
    Nat. Immunol., 2011-04-24;12(6):568-75.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  309. Smad1 signaling restricts hematopoietic potential after promoting hemangioblast commitment.
    Authors: Cook BD, Liu S, Evans T
    Blood, 2011-04-22;117(24):6489-97.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  310. Contribution of IL-17-producing gamma delta T cells to the efficacy of anticancer chemotherapy.
    Authors: Ma Y, Aymeric L, Locher C, Mattarollo SR, Delahaye NF, Pereira P, Boucontet L, Apetoh L, Ghiringhelli F, Casares N, Lasarte JJ, Matsuzaki G, Ikuta K, Ryffel B, Benlagha K, Tesniere A, Ibrahim N, Dechanet-Merville J, Chaput N, Smyth MJ, Kroemer G, Zitvogel L
    J. Exp. Med., 2011-03-07;208(3):491-503.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  311. Antigen-specific Th9 cells exhibit uniqueness in their kinetics of cytokine production and short retention at the inflammatory site.
    Authors: Tan C, Aziz MK, Lovaas JD, Vistica BP, Shi G, Wawrousek EF, Gery I
    J. Immunol., 2010-10-22;185(11):6795-801.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  312. TIM-3: a novel regulatory molecule of alloimmune activation.
    Authors: Boenisch O, D'Addio F, Watanabe T, Elyaman W, Magee CN, Yeung MY, Padera RF, Rodig SJ, Murayama T, Tanaka K, Yuan X, Ueno T, Jurisch A, Mfarrej B, Akiba H, Yagita H, Najafian N
    J. Immunol., 2010-10-18;185(10):5806-19.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  313. Interleukin-1 family cytokines as mucosal vaccine adjuvants for induction of protective immunity against influenza virus.
    Authors: Kayamuro H, Yoshioka Y, Abe Y, Arita S, Katayama K, Nomura T, Yoshikawa T, Kubota-Koketsu R, Ikuta K, Okamoto S, Mori Y, Kunisawa J, Kiyono H, Itoh N, Nagano K, Kamada H, Tsutsumi Y, Tsunoda S
    J. Virol., 2010-09-29;84(24):12703-12.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  314. Naive and activated T cells display differential responsiveness to TL1A that affects Th17 generation, maintenance, and proliferation.
    Authors: Jones GW, Stumhofer JS, Foster T, Twohig JP, Hertzog P, Topley N, Williams AS, Hunter CA, Jenkins BJ, Wang EC, Jones SA
    FASEB J., 2010-09-08;25(1):409-19.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  315. Regulation of the IL-21 gene by the NF-kappaB transcription factor c-Rel.
    Authors: Chen G, Hardy K, Bunting K
    J. Immunol., 2010-07-16;185(4):2350-9.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  316. Cell adhesion molecules regulate fibrotic process via Th1/Th2/Th17 cell balance in a bleomycin-induced scleroderma model.
    Authors: Yoshizaki A, Yanaba K, Iwata Y
    J. Immunol., 2010-07-12;185(4):2502-15.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  317. Loss of CD4+ T cell IL-6R expression during inflammation underlines a role for IL-6 trans signaling in the local maintenance of Th17 cells.
    Authors: Jones GW, McLoughlin RM, Hammond VJ, Parker CR, Williams JD, Malhotra R, Scheller J, Williams AS, Rose-John S, Topley N, Jones SA
    J. Immunol., 2010-01-18;184(4):2130-9.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  318. Thymic regulation of autoimmune disease by accelerated differentiation of Foxp3+ regulatory T cells through IL-7 signaling pathway.
    Authors: Chen X, Fang L, Song S, Guo TB, Liu A, Zhang JZ
    J. Immunol., 2009-10-19;183(10):6135-44.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  319. Activation of the NLRP3 inflammasome in dendritic cells induces IL-1beta-dependent adaptive immunity against tumors.
    Authors: Ghiringhelli F, Apetoh L, Tesniere A, Aymeric L, Ma Y, Ortiz C, Vermaelen K, Panaretakis T, Mignot G, Ullrich E, Perfettini JL, Schlemmer F, Tasdemir E, Uhl M, Genin P, Civas A, Ryffel B, Kanellopoulos J, Tschopp J, Andre F, Lidereau R, McLaughlin NM, Haynes NM, Smyth MJ, Kroemer G, Zitvogel L
    Nat. Med., 2009-09-20;15(10):1170-8.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  320. Externalization of the leaderless cytokine IL-1F6 occurs in response to lipopolysaccharide/ATP activation of transduced bone marrow macrophages.
    Authors: Martin U, Scholler J, Gurgel J, Renshaw B, Sims JE, Gabel CA
    J. Immunol., 2009-08-28;183(6):4021-30.
    Species: Mouse
    Sample Types: Buffer
    Applications: Western Blot
  321. Stratification is the key: inflammatory biomarkers accurately direct immunomodulatory therapy in experimental sepsis.
    Authors: Osuchowski MF, Connett J, Welch K, Granger J, Remick DG
    Crit. Care Med., 2009-05-01;37(5):1567-73.
    Applications: ELISA (Standard)
  322. Disruption of interleukin-1 signaling improves the quality of wound healing.
    Authors: Thomay AA, Daley JM, Sabo E, Worth PJ, Shelton LJ, Harty MW, Reichner JS, Albina JE
    Am. J. Pathol., 2009-04-23;174(6):2129-36.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  323. ST2 deficient mice display a normal host defense against pulmonary infection with Mycobacterium tuberculosis.
    Authors: Wieland CW, van der Windt GJ, Florquin S, McKenzie AN, van der Poll T
    Microbes Infect., 2009-03-13;11(4):524-30.
    Applications: ELISA (Standard)
  324. Role of Tim-3/galectin-9 inhibitory interaction in viral-induced immunopathology: shifting the balance toward regulators.
    Authors: Sehrawat S, Suryawanshi A, Hirashima M, Rouse BT
    J. Immunol., 2009-03-01;182(5):3191-201.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  325. IL-6 loss causes ventricular dysfunction, fibrosis, reduced capillary density, and dramatically alters the cell populations of the developing and adult heart.
    Authors: Banerjee I, Fuseler JW, Intwala AR, Baudino TA
    Am. J. Physiol. Heart Circ. Physiol., 2009-02-20;296(5):H1694-704.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  326. The induction of antibody production by IL-6 is indirectly mediated by IL-21 produced by CD4+ T cells.
    Authors: Dienz O, Eaton SM, Bond JP, Neveu W, Moquin D, Noubade R, Briso EM, Charland C, Leonard WJ, Ciliberto G, Teuscher C, Haynes L, Rincon M
    J. Exp. Med., 2009-01-12;206(1):69-78.
    Species: Mouse
    Sample Types: In Vivo, Whole Cells
    Applications: Bioassay, In Vivo
  327. The role of interleukin-6 in lipopolysaccharide-induced fever by mechanisms independent of prostaglandin E2.
    Authors: Nilsberth C, Elander L, Hamzic N, Norell M, Lonn J, Engstrom L, Blomqvist A
    Endocrinology, 2008-11-20;150(4):1850-60.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  328. A potential role of thymic stromal lymphopoietin in the recruitment of macrophages to mouse intervertebral disc cells via monocyte chemotactic protein 1 induction: implications for herniated discs.
    Authors: Ohba T, Haro H, Ando T, Koyama K, Hatsushika K, Suenaga F, Ohnuma Y, Nakamura Y, Katoh R, Ogawa H, Hamada Y, Nakao A
    Arthritis Rheum., 2008-11-01;58(11):3510-9.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  329. TH17 cells mediate steroid-resistant airway inflammation and airway hyperresponsiveness in mice.
    Authors: McKinley L, Alcorn JF, Peterson A, Dupont RB, Kapadia S, Logar A, Henry A, Irvin CG, Piganelli JD, Ray A, Kolls JK
    J. Immunol., 2008-09-15;181(6):4089-97.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  330. Engagement of the type I interferon receptor on dendritic cells inhibits T helper 17 cell development: role of intracellular osteopontin.
    Authors: Shinohara ML, Kim JH, Garcia VA, Cantor H
    Immunity, 2008-07-18;29(1):68-78.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  331. Adiponectin blocks multiple signaling cascades associated with leptin-induced cell proliferation in Apc Min/+ colon epithelial cells.
    Authors: Fenton JI, Birmingham JM, Hursting SD, Hord NG
    Int. J. Cancer, 2008-06-01;122(11):2437-45.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  332. Both Th1 and Th17 are immunopathogenic but differ in other key biological activities.
    Authors: Cox CA, Shi G, Yin H, Vistica BP, Wawrousek EF, Chan CC, Gery I
    J. Immunol., 2008-06-01;180(11):7414-22.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  333. GP130-STAT3 regulates epithelial cell migration and is required for repair of the bronchiolar epithelium.
    Authors: Kida H, Mucenski ML, Thitoff AR, Le Cras TD, Park KS, Ikegami M, Muller W, Whitsett JA
    Am. J. Pathol., 2008-05-08;172(6):1542-54.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  334. The type I IFN induction pathway constrains Th17-mediated autoimmune inflammation in mice.
    Authors: Guo B, Chang EY, Cheng G
    J. Clin. Invest., 2008-05-01;118(5):1680-90.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  335. Sphingosine 1-phosphate regulates the egress of IgA plasmablasts from Peyer's patches for intestinal IgA responses.
    Authors: Gohda M, Kunisawa J, Miura F, Kagiyama Y, Kurashima Y, Higuchi M, Ishikawa I, Ogahara I, Kiyono H
    J. Immunol., 2008-04-15;180(8):5335-43.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  336. CD14 contributes to pulmonary inflammation and mortality during murine tuberculosis.
    Authors: Wieland CW, van der Windt GJ, Wiersinga WJ, Florquin S, van der Poll T
    Immunology, 2008-04-03;125(2):272-9.
    Applications: ELISA (Standard)
  337. Tumor-specific Th17-polarized cells eradicate large established melanoma.
    Authors: Muranski P, Boni A, Antony PA, Cassard L, Irvine KR, Kaiser A, Paulos CM, Palmer DC, Touloukian CE, Ptak K, Gattinoni L, Wrzesinski C, Hinrichs CS, Kerstann KW, Feigenbaum L, Chan CC, Restifo NP
    Blood, 2008-03-19;112(2):362-73.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  338. Local stimulation of the adenosine A2B receptors induces an increased release of IL-6 in mouse striatum: an in vivo microdialysis study.
    Authors: Vazquez JF, Clement HW, Sommer O, Schulz E, van Calker D
    J. Neurochem., 2007-12-15;105(3):904-9.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  339. IL-17B and IL-17C are associated with TNF-alpha production and contribute to the exacerbation of inflammatory arthritis.
    Authors: Yamaguchi Y, Fujio K, Shoda H, Okamoto A, Tsuno NH, Takahashi K, Yamamoto K
    J. Immunol., 2007-11-15;179(10):7128-36.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  340. TGF-beta and IL-6 drive the production of IL-17 and IL-10 by T cells and restrain T(H)-17 cell-mediated pathology.
    Authors: McGeachy MJ, Bak-Jensen KS, Chen Y, Tato CM, Blumenschein W, McClanahan T, Cua DJ
    Nat. Immunol., 2007-11-11;8(12):1390-7.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  341. Maternal immune activation alters fetal brain development through interleukin-6.
    Authors: Smith SE, Li J, Garbett K, Mirnics K, Patterson PH
    J. Neurosci., 2007-10-03;27(40):10695-702.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  342. Interleukin-6 as a mechanism for the adverse effects of social stress on acute Theiler's virus infection.
    Authors: Meagher MW, Johnson RR, Young EE, Vichaya EG, Lunt S, Hardin EA, Connor MA, Welsh CJ
    Brain Behav. Immun., 2007-06-25;21(8):1083-95.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  343. Effect of chronic IL-6 infusion on acute pressor responses to vasoconstrictors in mice.
    Authors: Boesen EI, Pollock DM
    Am. J. Physiol. Heart Circ. Physiol., 2007-06-08;293(3):H1745-9.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  344. Induction of a distinct CD8 Tnc17 subset by transforming growth factor-beta and interleukin-6.
    Authors: Liu SJ, Tsai JP, Shen CR, Sher YP, Hsieh CL, Yeh YC, Chou AH, Chang SR, Hsiao KN, Yu FW, Chen HW
    J. Leukoc. Biol., 2007-05-15;82(2):354-60.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  345. High pressure promotes monocyte adhesion to the vascular wall.
    Authors: Riou S, Mees B, Esposito B, Merval R, Vilar J, Stengel D, Ninio E, van Haperen R, de Crom R, Tedgui A, Lehoux S
    Circ. Res., 2007-03-29;100(8):1226-33.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  346. Osteoblasts support B-lymphocyte commitment and differentiation from hematopoietic stem cells.
    Authors: Zhu J, Garrett R, Jung Y, Zhang Y, Kim N, Wang J, Joe GJ, Hexner E, Choi Y, Taichman RS, Emerson SG
    Blood, 2007-01-16;109(9):3706-12.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  347. Inactivated Sendai virus particles eradicate tumors by inducing immune responses through blocking regulatory T cells.
    Authors: Kurooka M, Kaneda Y
    Cancer Res., 2007-01-01;67(1):227-36.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  348. Circulating cytokine/inhibitor profiles reshape the understanding of the SIRS/CARS continuum in sepsis and predict mortality.
    Authors: Osuchowski MF, Welch K, Siddiqui J, Remick DG
    J. Immunol., 2006-08-01;177(3):1967-74.
    Applications: ELISA (Standard)
  349. Adenoviral-mediated overexpression of SOCS3 enhances IgG immune complex-induced acute lung injury.
    Authors: Gao H, Hoesel LM, Guo RF, Rancilio NJ, Sarma JV, Ward PA
    J. Immunol., 2006-07-01;177(1):612-20.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  350. Somatic activation of a conditional KrasG12D allele causes ineffective erythropoiesis in vivo.
    Authors: Braun BS, Archard JA, Van Ziffle JA, Tuveson DA, Jacks TE, Shannon K
    Blood, 2006-05-23;108(6):2041-4.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  351. Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells.
    Authors: Bettelli E, Carrier Y, Gao W, Korn T, Strom TB, Oukka M, Weiner HL, Kuchroo VK
    Nature, 2006-04-30;441(7090):235-8.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  352. The pulmonary and hepatic immune microenvironment and its contribution to the early systemic inflammation following blunt chest trauma.
    Authors: Perl M, Gebhard F, Braumuller S, Tauchmann B, Bruckner UB, Kinzl L, Knoferl MW
    Crit. Care Med., 2006-04-01;34(4):1152-9.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  353. Glechoma hederacea inhibits inflammatory mediator release in IFN-gamma and LPS-stimulated mouse peritoneal macrophages.
    Authors: An HJ, Jeong HJ, Um JY, Kim HM, Hong SH
    J Ethnopharmacol, 2006-03-10;106(3):418-24.
    Applications: ELISA (Standard)
  354. Pivotal role of endogenous tachykinins and the NK1 receptor in mediating leukocyte accumulation, in the absence of oedema formation, in response to TNFalpha in the cutaneous microvasculature.
    Authors: Costa SK, Yshii LM, Poston RN, Muscara MN, Brain SD
    J. Neuroimmunol., 2005-11-02;171(1):99-109.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  355. SLAM family markers are conserved among hematopoietic stem cells from old and reconstituted mice and markedly increase their purity.
    Authors: Yilmaz OH, Kiel MJ, Morrison SJ
    Blood, 2005-10-11;107(3):924-30.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  356. Hemojuvelin is essential for dietary iron sensing, and its mutation leads to severe iron overload.
    Authors: Niederkofler V, Salie R, Arber S
    J. Clin. Invest., 2005-08-01;115(8):2180-6.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  357. Role of interleukin-6 in cardiomyocyte/cardiac fibroblast interactions during myocyte hypertrophy and fibroblast proliferation.
    Authors: Fredj S, Bescond J, Louault C, Delwail A, Potreau D
    J. Cell. Physiol., 2005-08-01;204(2):428-36.
    Applications: ELISA (Standard)
  358. Sequential ELISA to profile multiple cytokines from small volumes.
    Authors: Osuchowski MF, Siddiqui J, Copeland S, Remick DG
    J. Immunol. Methods, 2005-07-01;302(1):172-81.
    Applications: ELISA (Standard)
  359. Selective macrophage suppression during sepsis.
    Authors: Ellaban E, Bolgos G, Remick D
    Cell. Immunol., 2005-02-26;231(1):103-11.
    Applications: ELISA (Standard)
  360. CXCR2-/- mice show enhanced susceptibility to herpetic stromal keratitis: a role for IL-6-induced neovascularization.
    Authors: Banerjee K, Biswas PS, Kim B, Lee S, Rouse BT
    J. Immunol., 2004-01-15;172(2):1237-45.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  361. Cardiotrophin-1 in choroid plexus and the cerebrospinal fluid circulatory system.
    Authors: Gard AL, Gavin E, Solodushko V, Pennica D
    Neuroscience, 2004-01-01;127(1):43-52.
    Applications: Western Blot
  362. The IL-6 family cytokines, interleukin-6, interleukin-11, oncostatin M, and leukemia inhibitory factor, enhance mast cell growth through fibroblast-dependent pathway in mice.
    Authors: Gyotoku E, Morita E, Kameyoshi Y, Hiragun T, Yamamoto S, Hide M
    Arch. Dermatol. Res., 2001-11-01;293(10):508-14.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  363. Interleukin-6 and the granulocyte colony-stimulating factor receptor are major independent regulators of granulopoiesis in vivo but are not required for lineage commitment or terminal differentiation.
    Authors: Liu F, Poursine-Laurent J, Wu HY, Link DC
    Blood, 1997-10-01;90(7):2583-90.
    Species: Mouse
    Sample Types: In Vivo, Whole Cells
    Applications: Bioassay, In Vivo

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By Anonymous on 11/15/2023
Application: CellProlif
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Application: CellProlif
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Application: In vitro bioactivity in cell culture
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Application: SDS-PAGE Control

Recombinant IL6 served as positive control.

SDS-PAGE Control Recombinant Mouse IL-6 Protein 406-ML
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Application: Cell Adhesion
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Application: In vitro bioactivity in cell culture
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Application: CellProlif
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Reason for Rating: Binding observed by Sirukumab
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Application: Stem/Immune cell maintenance or differentiation
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Application: Binding assay/Protein-protein interaction