Mouse IL-6 DuoSet ELISA Summary
* Provided that the recommended microplates, buffers, diluents, substrates and solutions are used, and the assay is run as summarized in the Assay Procedure provided.
This DuoSet ELISA Development kit contains the basic components required for the development of sandwich ELISAs to measure natural and recombinant mouse IL-6. The suggested diluent is suitable for the analysis of most cell culture supernate samples. Diluents for complex matrices, such as serum and plasma, should be evaluated prior to use in this DuoSet.
Product Features
- Optimized capture and detection antibody pairings with recommended concentrations save lengthy development time
- Development protocols are provided to guide further assay optimization
- Assay can be customized to your specific needs
- Economical alternative to complete kits
Kit Content
- Capture Antibody
- Detection Antibody
- Recombinant Standard
- Streptavidin conjugated to horseradish-peroxidase (Streptavidin-HRP)
Other Reagents Required
DuoSet Ancillary Reagent Kit 2 (5 plates): (Catalog # DY008) containing 96 well microplates, plate sealers, substrate solution, stop solution, plate coating buffer (PBS), wash buffer, and Reagent Diluent Concentrate 2.
The components listed above may be purchased separately:
PBS: (Catalog # DY006), or 137 mM NaCl, 2.7 mM KCl, 8.1 mM Na2HPO4, 1.5 mM KH2PO4, pH 7.2 - 7.4, 0.2 µm filtered
Wash Buffer: (Catalog # WA126), or 0.05% Tween® 20 in PBS, pH 7.2-7.4
Reagent Diluent: (Catalog # DY995), or 1% BSA in PBS, pH 7.2-7.4, 0.2 µm filtered
Substrate Solution: 1:1 mixture of Color Reagent A (H2O2) and Color Reagent B (Tetramethylbenzidine) (Catalog # DY999)
Stop Solution: 2 N H2SO4 (Catalog # DY994)
Microplates: R&D Systems (Catalog # DY990)
Plate Sealers: ELISA Plate Sealers (Catalog # DY992)
Scientific Data
Product Datasheets
Preparation and Storage
Background: IL-6
Interleukin 6 (IL-6) is a pleiotropic, a-helical, 22-28 kDa phosphorylated and variably glycosylated cytokine that plays important roles in the acute phase reaction, inflammation, hematopoiesis, bone metabolism, and cancer progression. Mature human IL-6 is 183 amino acids (aa) in length and shares 39% aa sequence identity with mouse and rat IL-6. Alternative splicing generates several isoforms with internal deletions, some of which exhibit antagonistic properties. Cells known to express IL-6 include CD8+ T cells, fibroblasts, synoviocytes, adipocytes, osteoblasts, megakaryocytes, endothelial cells (under the influence of endothelins), sympathetic neurons, cerebral cortex neurons, adrenal medulla chromaffin cells, retinal pigment cells, mast cells, keratinocytes, Langerhans cells, fetal and adult astrocytes, neutrophils, monocytes, eosinophils, colonic epithelial cells, B1 B cells and pancreatic islet beta cells. IL-6 production is generally correlated with cell activation and is normally kept in control by glucocorticoids, catecholamines, and secondary sex steroids. Normal human circulating IL-6 is in the 1 pg/mL range, with slight elevations during the menstrual cycle, modest elevations in certain cancers, and large elevations after surgery.
IL-6 induces signaling through a cell surface heterodimeric receptor complex composed of a ligand binding subunit (IL-6 R alpha) and a signal transducing subunit (gp130). IL-6 binds to IL-6 Ra, triggering IL-6 Ra association with gp130 and gp130 dimerization. gp130 is also a component of the receptors for CLC, CNTF, CT-1, IL-11, IL-27, LIF, and OSM. Soluble forms of IL-6 Ra are generated by both alternative splicing and proteolytic cleavage. In a mechanism known as trans-signaling, complexes of soluble IL-6 and IL-6 Ra elicit responses from gp130-expressing cells that lack cell surface IL-6 Ra. Trans-signaling enables a wider range of cell types to respond to IL-6, as the expression of gp130 is ubiquitous, while that of IL-6 Ra is predominantly restricted to hepatocytes, monocytes, and resting lymphocytes. Soluble splice forms of gp130 block trans-signaling from IL-6/IL-6 Ra but not from other cytokines that use gp130 as a co-receptor.
IL-6, along with TNF-a and IL-1, drives the acute inflammatory response. IL-6 is almost solely responsible for fever and the acute phase response in the liver, and it is important in the transition from acute inflammation to either acquired immunity or chronic inflammatory disease. When dysregulated, it contributes to chronic inflammation in conditions such as obesity, insulin resistance, inflammatory bowel disease, arthritis, and sepsis. IL-6 modulates bone resorption and is a major effector of inflammatory joint destruction in rheumatoid arthritis through its promotion of Th17 cell development and activity. It contributes to atherosclerotic plaque development and destabilization as well as the development of inflammation-associated carcinogenesis.
Assay Procedure
GENERAL ELISA PROTOCOL
Plate Preparation
- Dilute the Capture Antibody to the working concentration in PBS without carrier protein. Immediately coat a 96-well microplate with 100 μL per well of the diluted Capture Antibody. Seal the plate and incubate overnight at room temperature.
- Aspirate each well and wash with Wash Buffer, repeating the process two times for a total of three washes. Wash by filling each well with Wash Buffer (400 μL) using a squirt bottle, manifold dispenser, or autowasher. Complete removal of liquid at each step is essential for good performance. After the last wash, remove any remaining Wash Buffer by aspirating or by inverting the plate and blotting it against clean paper towels.
- Block plates by adding 300 μL Reagent Diluent to each well. Incubate at room temperature for a minimum of 1 hour.
- Repeat the aspiration/wash as in step 2. The plates are now ready for sample addition.
Assay Procedure
- Add 100 μL of sample or standards in Reagent Diluent, or an appropriate diluent, per well. Cover with an adhesive strip and incubate 2 hours at room temperature.
- Repeat the aspiration/wash as in step 2 of Plate Preparation.
- Add 100 μL of the Detection Antibody, diluted in Reagent Diluent, to each well. Cover with a new adhesive strip and incubate 2 hours at room temperature.
- Repeat the aspiration/wash as in step 2 of Plate Preparation.
- Add 100 μL of the working dilution of Streptavidin-HRP to each well. Cover the plate and incubate for 20 minutes at room temperature. Avoid placing the plate in direct light.
- Repeat the aspiration/wash as in step 2.
- Add 100 μL of Substrate Solution to each well. Incubate for 20 minutes at room temperature. Avoid placing the plate in direct light.
- Add 50 μL of Stop Solution to each well. Gently tap the plate to ensure thorough mixing.
- Determine the optical density of each well immediately, using a microplate reader set to 450 nm. If wavelength correction is available, set to 540 nm or 570 nm. If wavelength correction is not available, subtract readings at 540 nm or 570 nm from the readings at 450 nm. This subtraction will correct for optical imperfections in the plate. Readings made directly at 450 nm without correction may be higher and less accurate.
Citations for Mouse IL-6 DuoSet ELISA
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
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Citations: Showing 1 - 10
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Tumor-induced natural killer cell dysfunction is a rapid and reversible process uncoupled from the expression of immune checkpoints
Authors: Pouxvielh, K;Marotel, M;Drouillard, A;Villard, M;Moreews, M;Bossan, A;Poiget, M;Khoryati, L;Benezech, S;Fallone, L;Hamada, S;Rousseaux, N;Picq, L;Rocca, Y;Berton, A;Teixeira, M;Mathieu, AL;Ainouze, M;Hasan, U;Fournier, A;Thaunat, O;Marçais, A;Walzer, T;
Science advances
Species: Mouse
Sample Types: Cell Culture Supernates
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The potential therapeutic role of itaconate and mesaconate on the detrimental effects of LPS-induced neuroinflammation in the brain
Authors: Ohm, M;Hosseini, S;Lonnemann, N;He, W;More, T;Goldmann, O;Medina, E;Hiller, K;Korte, M;
Journal of neuroinflammation
Species: Mouse
Sample Types: Cell Culture Supernates
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The Impact of Extracellular Histones and Absence of Toll-like Receptors on Cardiac Functional and Electrical Disturbances in Mouse Hearts
Authors: Loaiza, R;Fattahi, F;Kalbitz, M;Grailer, JJ;Russell, MW;Jalife, J;Valdivia, HH;Zetoune, FS;Ward, PA;
International journal of molecular sciences
Species: Mouse, Transgenic Mouse
Sample Types: Complex Sample Type
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H7N7 viral infection elicits pronounced, sex-specific neuroinflammatory responses in vitro
Authors: Gabele, L;Bochow, I;Rieke, N;Sieben, C;Michaelsen-Preusse, K;Hosseini, S;Korte, M;
Frontiers in cellular neuroscience
Species: Mouse
Sample Types: Cell Culture Supernates
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A Natural deep eutectic solvent as an effective material for dual debridement and antibiofilm effects in chronic wound treatment
Authors: Map Schuh, C;Ezquer, F;Mamani, S;Campodónico, PR;Cárcamo, C;Martinez-Gómez, F;Aburto, I;Ezquer, M;Morales, B;Olivares, B;
International journal of pharmaceutics
Species: Mouse
Sample Types: Cell Culture Supernates
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Dihydrothiazolo ring-fused 2-pyridone antimicrobial compounds treat Streptococcus pyogenes skin and soft tissue infection
Authors: Zou, Z;Singh, P;Pinkner, JS;Obernuefemann, CLP;Xu, W;Nye, TM;Dodson, KW;Almqvist, F;Hultgren, SJ;Caparon, MG;
Science advances
Species: Mouse
Sample Types: Serum
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Macrophage-fibroblast crosstalk drives Arg1-dependent lung fibrosis via ornithine loading
Authors: Yadav, P;Ortega, JG;Tamaki, W;Chien, C;Chang, KC;Biswas, N;Pan, S;Nilsson, J;Yin, X;Bhattacharyya, A;Boostanpour, K;Jujaray, T;Wang, J;Tsukui, T;Sheppard, D;Li, B;Maishan, M;Taenaka, H;Matthay, MA;Muramatsu, R;Maliskova, L;Ghosh, A;Eckalbar, WL;Molofsky, AB;Wolters, PJ;Tamaki, SJ;Bivona, T;Abate, AR;Wagner, A;Tharp, KM;Bhattacharya, M;
bioRxiv : the preprint server for biology
Species: Mouse, Transgenic Mouse
Sample Types: Cell Culture Supernates, BALF
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Anti-Neuroinflammatory Effects of Ginkgo biloba Extract EGb 761 in LPS-Activated BV2 Microglial Cells
Authors: Sun, L;Apweiler, M;Tirkey, A;Klett, D;Normann, C;Dietz, GPH;Lehner, MD;Fiebich, BL;
International journal of molecular sciences
Species: Mouse
Sample Types: Cell Culture Supernates
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Sphinganine recruits TLR4 adaptors in macrophages and promotes inflammation in murine models of sepsis and melanoma
Authors: Hering, M;Madi, A;Sandhoff, R;Ma, S;Wu, J;Mieg, A;Richter, K;Mohr, K;Knabe, N;Stichling, D;Poschet, G;Bestvater, F;Frank, L;Utikal, J;Umansky, V;Cui, G;
Nature communications
Species: Mouse
Sample Types: Cell Culture Supernates, Plasma
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Rujin Jiedu decoction protects against influenza virus infection by modulating gut microbiota
Authors: Huang, Q;Yang, G;Tang, C;Dou, B;Hu, Y;Liu, H;Wu, X;Zhang, H;Wang, H;Xu, L;Yang, XD;Xu, Y;Zheng, Y;
Heliyon
Species: Mouse
Sample Types: Cell Culture Supernates
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Acute effects of atrazine on the immunoexpressions of Sertoli and germ cells molecular markers, cytokines, chemokines, and sex hormones levels in mice testes and epididymides
Authors: Abarikwu, SO;Coimbra, JLP;Campolina-Silva, G;Rocha, ST;Costa, VV;Lacerda, SMSN;Costa, GMJ;
Chemosphere
Species: Mouse
Sample Types: Tissue Homogenates
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Neutrophil extracellular traps promote immunopathogenesis of virus-induced COPD exacerbations
Authors: Katsoulis, O;Toussaint, M;Jackson, MM;Mallia, P;Footitt, J;Mincham, KT;Meyer, GFM;Kebadze, T;Gilmour, A;Long, M;Aswani, AD;Snelgrove, RJ;Johnston, SL;Chalmers, JD;Singanayagam, A;
Nature communications
Species: Mouse
Sample Types: BALF
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Poly(allylamine)-tripolyphosphate polymeric nanoparticle as an NLRP3-dependent systemic adjuvant for the vaccine development
Authors: Rizzo, GP;Sanches, RC;Chavero, C;Bianchi, DS;Apuzzo, E;Herrera, SE;Agazzi, ML;Keitelman, IA;Trevani, AS;Oliveira, SC;Azzaroni, O;Smaldini, PL;Docena, GH;
bioRxiv : the preprint server for biology
Species: Mouse
Sample Types: Cell Culture Supernates
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ATG16L1 in myeloid cells limits colorectal tumor growth in ApcMin/+ mice infected with colibactin-producing Escherichia coli via decreasing inflammasome activation
Authors: Salesse, L;Duval, A;Sauvanet, P;Da Silva, A;Barnich, N;Godfraind, C;Dalmasso, G;Nguyen, HTT;
Autophagy
Species: Mouse
Sample Types: Cell Culture Supernates
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Absence of c-Maf and IL-10 enables Type I IFN enhancement of innate responses to low-dose LPS in alveolar macrophages
Authors: Lim, PN;Cervantes, MM;Pham, LK;Doherty, S;Tufts, A;Dubey, D;Mai, D;Aderem, A;Diercks, AH;Rothchild, AC;
bioRxiv : the preprint server for biology
Species: Mouse
Sample Types: Cell Culture Supernates
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Comparison of the transcriptome, lipidome, and c-di-GMP production between BCG?BCG1419c and BCG, with Mincle- and Myd88-dependent induction of proinflammatory cytokines in murine macrophages
Authors: Flores-Valdez, MA;Peterson, EJR;Aceves-Sánchez, MJ;Baliga, NS;Morita, YS;Sparks, IL;Saini, DK;Yadav, R;Lang, R;Mata-Espinosa, D;León-Contreras, JC;Hernández-Pando, R;
Scientific reports
Species: Mouse, Transgenic Mouse
Sample Types: Cell Culture Supernates
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Impaired autophagy in myeloid cells aggravates psoriasis-like skin inflammation through the IL-1?/CXCL2/neutrophil axis
Authors: Lee, J;Kim, MY;Kim, HJ;Choi, WS;Kim, HS;
Cell & bioscience
Species: Transgenic Mouse
Sample Types: Cell Culture Supernates
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Airway epithelial CD47 plays a critical role in inducing influenza virus-mediated bacterial super-infection
Authors: Moon, S;Han, S;Jang, IH;Ryu, J;Rha, MS;Cho, HJ;Yoon, SS;Nam, KT;Kim, CH;Park, MS;Seong, JK;Lee, WJ;Yoon, JH;Chung, YW;Ryu, JH;
Nature communications
Species: Mouse
Sample Types: BALF
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Electrical stimulation of the dorsal motor nucleus of the vagus in male mice can regulate inflammation without affecting the heart rate
Authors: Falvey, A;Palandira, SP;Chavan, SS;Brines, M;Dantzer, R;Tracey, KJ;Pavlov, VA;
Brain, behavior, and immunity
Species: Mouse
Sample Types: Serum, Tissue Homogenates
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Anti-Neuroinflammatory Effects of a Macrocyclic Peptide-Peptoid Hybrid in Lipopolysaccharide-Stimulated BV2 Microglial Cells
Authors: Sun, L;Wilke Saliba, S;Apweiler, M;Akmermer, K;Herlan, C;Grathwol, C;de Oliveira, ACP;Normann, C;Jung, N;Bräse, S;Fiebich, BL;
International journal of molecular sciences
Species: Mouse
Sample Types: Cell Culture Supernates
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Tumor Cell-Associated IL-1? Affects Breast Cancer Progression and Metastasis in Mice through Manipulation of the Tumor Immune Microenvironment
Authors: Krishnamohan, M;Kaplanov, I;Maudi-Boker, S;Yousef, M;Machluf-Katz, N;Cohen, I;Elkabets, M;Titus, J;Bersudsky, M;Apte, RN;Voronov, E;Braiman, A;
International journal of molecular sciences
Species: Mouse, Transgenic Mouse
Sample Types:
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A palmitoylation-depalmitoylation relay spatiotemporally controls GSDMD activation in pyroptosis
Authors: Zhang, N;Zhang, J;Yang, Y;Shan, H;Hou, S;Fang, H;Ma, M;Chen, Z;Tan, L;Xu, D;
Nature cell biology
Species: Mouse
Sample Types: Serum, Cell Culture Supernates
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LRRK2 G2019S Promotes Colon Cancer Potentially via LRRK2-GSDMD Axis-Mediated Gut Inflammation
Authors: Wang, Y;Gao, JZ;Sakaguchi, T;Maretzky, T;Gurung, P;Narayanan, NS;Short, S;Xiong, Y;Kang, Z;
Cells
Species: Transgenic Mouse
Sample Types: Cell Culture Supernates
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DNA corona on nanoparticles leads to an enhanced immunostimulatory effect with implications for autoimmune diseases
Authors: Anees, F;Montoya, DA;Pisetsky, DS;Payne, CK;
Proceedings of the National Academy of Sciences of the United States of America
Species: Mouse
Sample Types: Cell Culture Supernates
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Chitosan/dialdehyde cellulose hydrogels with covalently anchored polypyrrole: Novel conductive, antibacterial, antioxidant, immunomodulatory, and anti-inflammatory materials
Authors: Ká?erová, S;Muchová, M;Doudová, H;Münster, L;Hanulíková, B;Valáková, K;Kapárková, V;Ku?itka, I;Humpolí?ek, P;Víchová, Z;Vaí?ek, O;Vícha, J;
Carbohydrate polymers
Species: Mouse
Sample Types: Cell Culture Supernates
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Protective Effects of Inulin on Stress-Recurrent Inflammatory Bowel Disease
Authors: Du, Y;Kusama, K;Hama, K;Chen, X;Tahara, Y;Kajiwara, S;Shibata, S;Orihara, K;
International journal of molecular sciences
Species: Mouse
Sample Types: Serum
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Viral afterlife: SARS-CoV-2 as a reservoir of immunomimetic peptides that reassemble into proinflammatory supramolecular complexes
Authors: Zhang, Y;Bharathi, V;Dokoshi, T;de Anda, J;Ursery, LT;Kulkarni, NN;Nakamura, Y;Chen, J;Luo, EWC;Wang, L;Xu, H;Coady, A;Zurich, R;Lee, MW;Matsui, T;Lee, H;Chan, LC;Schepmoes, AA;Lipton, MS;Zhao, R;Adkins, JN;Clair, GC;Thurlow, LR;Schisler, JC;Wolfgang, MC;Hagan, RS;Yeaman, MR;Weiss, TM;Chen, X;Li, MMH;Nizet, V;Antoniak, S;Mackman, N;Gallo, RL;Wong, GCL;
Proceedings of the National Academy of Sciences of the United States of America
Species: Mouse
Sample Types: Plasma
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Myeloid PHD2 Conditional Knockout Improves Intraplaque Angiogenesis and Vascular Remodeling in a Murine Model of Venous Bypass Grafting
Authors: Sluiter, TJ;Tillie, RJHA;de Jong, A;de Bruijn, JBG;Peters, HAB;van de Leijgraaf, R;Halawani, R;Westmaas, M;Starink, LIW;Quax, PHA;Sluimer, JC;de Vries, MR;
Journal of the American Heart Association
Species: Transgenic Mouse
Sample Types: Cell Culture Supernates
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Histone lactylation inhibits RAR? expression in macrophages to promote colorectal tumorigenesis through activation of TRAF6-IL-6-STAT3 signaling
Authors: Li, XM;Yang, Y;Jiang, FQ;Hu, G;Wan, S;Yan, WY;He, XS;Xiao, F;Yang, XM;Guo, X;Lu, JH;Yang, XQ;Chen, JJ;Ye, WL;Liu, Y;He, K;Duan, HX;Zhou, YJ;Gan, WJ;Liu, F;Wu, H;
Cell reports
Species: Mouse
Sample Types: Cell Lysates
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Dihydrothiazolo ring-fused 2-pyridone antimicrobial compounds treat Streptococcus pyogenes skin and soft tissue infection
Authors: Zou, Z;Obernuefemann, CLP;Singh, P;Pinkner, JS;Xu, W;Nye, TM;Dodson, KW;Almqvist, F;Hultgren, SJ;Caparon, MG;
bioRxiv : the preprint server for biology
Species: Mouse
Sample Types: Serum
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Pickering emulsions as an effective route for the preparation of bioactive composites: A study of nanocellulose/polyaniline particles with immunomodulatory effect
Authors: Korábková, E;Kapárková, V;Vaí?ek, O;Víchová, Z;Ká?erová, S;Valáková, K;Urbánková, L;Vícha, J;Münster, L;Skopalová, K;Humpolí?ek, P;
Carbohydrate polymers
Species: Mouse
Sample Types: Cell Culture Supernates
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NLRX1 Prevents M2 Macrophage Polarization and Excessive Renal Fibrosis in Chronic Obstructive Nephropathy
Authors: Liu, Y;Kors, L;Butter, LM;Stokman, G;Claessen, N;Zuurbier, CJ;Girardin, SE;Leemans, JC;Florquin, S;Tammaro, A;
Cells
Species: Mouse
Sample Types: Cell Culture Supernates, Tissue Homogenates
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Central activation of the fatty acid sensor GPR120 suppresses microglia reactivity and alleviates sickness- and anxiety-like behaviors
Authors: Nakajima, S;Demers, G;Machuca-Parra, AI;Pour, ZD;Bairamian, D;Bouyakdan, K;Fisette, A;Kabahizi, A;Robb, J;Rodaros, D;Laurent, C;Ferreira, G;Arbour, N;Alquier, T;Fulton, S;
Journal of neuroinflammation
Species: Mouse
Sample Types: Cell Culture Supernates
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Metformin inhibits paclitaxel-induced mechanical allodynia by activating opioidergic pathways and reducing cytokines production in the dorsal root ganglia and thalamus
Authors: Morais, MÍ;Braga, AV;Silva, RRL;Barbosa, BCM;Costa, SOAM;Rodrigues, FF;Melo, ISF;Matos, RC;Carobin, NV;Sabino, AP;Coelho, MM;Machado, RR;
Cytokine
Species: Mouse
Sample Types: Tissue Homogenates
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Keratin 15 protects against cigarette smoke-induced epithelial mesenchymal transformation by MMP-9
Authors: Zhu, W;Han, L;Wu, Y;Tong, L;He, L;Wang, Q;Yan, Y;Pan, T;Shen, J;Song, Y;Shen, Y;Zhu, Q;Zhou, J;
Respiratory research
Species: Mouse, Transgenic Mouse
Sample Types: BALF
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A 5-Lipoxygenase Inhibitor, Zileuton, Modulates Host Immune Responses and Improves Lung Function in a Model of Severe Acute Respiratory Syndrome (SARS) Induced by Betacoronavirus
Authors: Pereira, RDD;Rabelo, RAN;Oliveira, NFM;Porto, SLT;Andrade, ACDSP;Queiroz-Junior, CM;Barbosa, CLN;de Souza-Costa, LP;Santos, FRDS;Oliveira, FBR;da Silva, BLV;Umezu, HL;Ferreira, R;da Silva, GSF;Cruz, JS;Teixeira, MM;Costa, VV;Machado, FS;
Viruses
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Hydraulic calcium silicate-based root canal sealers mitigate proinflammatory cytokine synthesis and promote osteogenesis in vitro
Authors: Alchawoosh, A;Hashimoto, K;Kawashima, N;Noda, S;Nozaki, K;Okiji, T;
Journal of dental sciences
Species: Mouse
Sample Types: Cell Culture Supernates
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Chronic hyperpalatable diet induces impairment of hippocampal-dependent memories and alters glutamatergic and fractalkine axis signaling
Authors: Ribeiro, R;Silva, EG;Moreira, FC;Gomes, GF;Cussat, GR;Silva, BSR;da Silva, MCM;de Barros Fernandes, H;de Sena Oliveira, C;de Oliveira Guarnieri, L;Lopes, V;Ferreira, CN;de Faria, AMC;Maioli, TU;Ribeiro, FM;de Miranda, AS;Moraes, GSP;de Oliveira, ACP;Vieira, LB;
Scientific reports
Species: Mouse
Sample Types: Serum, Tissue Homogenates
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Inhibiting endothelial cell Mst1 attenuates acute lung injury in mice
Authors: Guo, ZF;Tongmuang, N;Li, C;Zhang, C;Hu, L;Capreri, D;Zuo, MX;Summer, R;Sun, J;
bioRxiv : the preprint server for biology
Species: Mouse
Sample Types: Tissue Homogenates, BALF
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Development of LB244, an Irreversible STING Antagonist
Authors: Barasa, L;Chaudhuri, S;Zhou, JY;Jiang, Z;Choudhary, S;Green, RM;Wiggin, E;Cameron, M;Humphries, F;Fitzgerald, KA;Thompson, PR;
Journal of the American Chemical Society
Species: Mouse
Sample Types: Serum
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Cefaclor causes vagus nerve-mediated depression-like symptoms with gut dysbiosis in mice
Authors: Joo, MK;Shin, YJ;Kim, DH;
Scientific reports
Species: Mouse
Sample Types: Tissue Homogenates
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Impact of Elevated Brain IL-6 in Transgenic Mice on the Behavioral and Neurochemical Consequences of Chronic Alcohol Exposure
Authors: Gruol, DL;Calderon, D;Huitron-Resendiz, S;Cates-Gatto, C;Roberts, AJ;
Cells
Species: Mouse
Sample Types: Cell Culture Supernates
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3,3-dimethyl-1-butanol and its metabolite 3,3-dimethylbutyrate ameliorate collagen-induced arthritis independent of choline trimethylamine lyase activity
Authors: Fechtner, S;Allen, BE;Chriswell, ME;Jubair, WK;Robertson, CE;Kofonow, JN;Frank, DN;Holers, VM;Kuhn, KA;
Research square
Species: Mouse
Sample Types: Cell Culture Supernates
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Innate immune control of influenza virus interspecies adaptation
Authors: Denz, PJ;Speaks, S;Kenney, AD;Eddy, AC;Papa, JL;Roettger, J;Scace, SC;Hemann, EA;Forero, A;Webby, RJ;Bowman, AS;Yount, JS;
bioRxiv : the preprint server for biology
Species: Mouse
Sample Types: Tissue Homogenates
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Short-Term Caloric Restriction and Subsequent Re-Feeding Compromise Liver Health and Associated Lipid Mediator Signaling in Aged Mice
Authors: Schädel, P;Wichmann-Costaganna, M;Czapka, A;Gebert, N;Ori, A;Werz, O;
Nutrients
Species: Mouse
Sample Types: Tissue Homogenates
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Genetic Downregulation of the Metabotropic Glutamate Receptor Type 5 Dampens the Reactive and Neurotoxic Phenotype of Adult ALS Astrocytes
Authors: Torazza, C;Provenzano, F;Gallia, E;Cerminara, M;Balbi, M;Bonifacino, T;Tessitore, S;Ravera, S;Usai, C;Musante, I;Puliti, A;Van Den Bosch, L;Jafar-Nejad, P;Rigo, F;Milanese, M;Bonanno, G;
Cells
Species: Mouse
Sample Types: Cell Culture Supernates
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Adenosine metabolized from extracellular ATP ameliorates organ injury by triggering A2BR signaling
Authors: Kelestemur, T;Németh, ZH;Pacher, P;Beesley, J;Robson, SC;Eltzschig, HK;Haskó, G;
Respiratory research
Species: Mouse
Sample Types: Plasma
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LRRK2 G2019S promotes the development of colon cancer via modulating intestinal inflammation
Authors: Wang, Y;Gao, JZ;Sakaguchi, T;Maretzky, T;Gurung, P;Short, S;Xiong, Y;Kang, Z;
bioRxiv : the preprint server for biology
Species: Mouse
Sample Types: Cell Culture Supernates
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Dysregulated Pulmonary Inflammatory Responses Exacerbate the Outcome of Secondary Aspergillosis Following Influenza
Authors: Lee, CK;Oliveira, LVN;Akalin, A;Specht, CA;Lourenco, D;Gomez, CL;Ramirez-Ortiz, ZG;Wang, JP;Levitz, SM;
bioRxiv : the preprint server for biology
Species: Mouse
Sample Types: Serum
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Pharmacologic inhibition of NLRP3 reduces the levels of ?-synuclein and protects dopaminergic neurons in a model of Parkinson's disease
Authors: Amo-Aparicio, J;Daly, J;Højen, JF;Dinarello, CA;
Journal of neuroinflammation
Species: Mouse
Sample Types: Tissue Homogenates
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Poly-?-caprolactone nanocapsules loaded with copaiba essential oil reduce inflammation and pain in mice
Authors: Pinto, EP;da Costa, SOAM;D'Haese, C;Nysten, B;Machado, FP;Rocha, LM;de Souza, TM;Beloqui, A;Machado, RR;Araújo, RS;
International journal of pharmaceutics
Species: Mouse
Sample Types: Tissue Homogenates
-
Autophagy prevents early proinflammatory responses and neutrophil recruitment during Mycobacterium tuberculosis infection without affecting pathogen burden in macrophages
Authors: Kinsella, RL;Kimmey, JM;Smirnov, A;Woodson, R;Gaggioli, MR;Chavez, SM;Kreamalmeyer, D;Stallings, CL;
PLoS biology
Species: Mouse
Sample Types: Cell Culture Supernates
-
Aging modulates homeostatic leukocyte trafficking to the peritoneal cavity in a sex-specific manner
Authors: Hopkin, SJ;Pezhman, L;Begum, J;Kavanagh, D;McGettrick, HM;Iqbal, AJ;Chimen, M;
Journal of leukocyte biology
Species: Mouse
Sample Types: Serum
-
The herbicides glyphosate and glufosinate and the cyanotoxin ?-N-methylamino-l-alanine induce long-term motor disorders following postnatal exposure: the importance of prior asymptomatic maternal inflammatory sensitization
Authors: Oummadi, A;Menuet, A;Méresse, S;Laugeray, A;Guillemin, G;Mortaud, S;
Frontiers in neuroscience
Species: Mouse
Sample Types: Peritoneal Lavage Fluid
-
Systemic Alterations in Type-2 Conventional Dendritic Cells Leads to Impaired Tumor Immunity in Pancreatic Cancer
Authors: James, CA;Baer, JM;Zuo, C;Panni, UY;Knolhoff, BL;Hogg, GD;Kingston, NL;Kang, LI;Lander, VE;Luo, J;Tao, Y;Watson, MA;Aft, R;Fields, RC;Hawkins, WG;DeNardo, DG;
Cancer immunology research
Species: Mouse
Sample Types: Serum
-
Soluble epoxide hydrolase inhibitor blockage microglial cell activation in subnucleus caudalis in a persistent model of arthritis
Authors: Tarkany Basting, R;Henrique Napimoga, M;Ant�nio Trindade Silva, C;Ballassini Abdalla, H;Campos Durso, B;Henrique Barboza Martins, L;de Abreu Cavalcanti, H;Hammock, BD;Trindade Clemente-Napimoga, J;
International immunopharmacology
Species: Mouse
Sample Types: Cell Culture Supernates, Tissue Homogenates
-
Fisetin, an Anti-Inflammatory Agent, Overcomes Radioresistance by Activating the PERK-ATF4-CHOP Axis in Liver Cancer
Authors: Kim, TW;
International journal of molecular sciences
Species: Mouse
Sample Types: Cell Culture Supernates
-
Electrical stimulation of the dorsal motor nucleus of the vagus regulates inflammation without affecting the heart rate
Authors: Falvey, A;Palandira, SP;Chavan, SS;Brines, M;Tracey, KJ;Pavlov, VA;
bioRxiv : the preprint server for biology
Species: Mouse
Sample Types: Serum, Tissue Homogenates
-
Thrombocytopenia Independently Leads to Monocyte Immune Dysfunction
Authors: Li, C;Ture, SK;Nieves-Lopez, B;Blick-Nitko, SK;Maurya, P;Livada, AC;Stahl, TJ;Kim, M;Pietropaoli, AP;Morrell, CN;
bioRxiv : the preprint server for biology
Species: Mouse
Sample Types: Cell Culture Supernates
-
Human Wharton's jelly mesenchymal stem cells derived-exosomes enriched by miR-124 promote an anti-fibrotic response in an experimental model of liver fibrosis
Authors: Niknam, B;Baghaei, K;Mahmoud Hashemi, S;Hatami, B;Reza Zali, M;Amani, D;
International immunopharmacology
Species: Mouse
Sample Types: Serum
-
Salmonella Enteritidis T1SS protein SiiD inhibits NLRP3 inflammasome activation via repressing the mtROS-ASC dependent pathway
Authors: Guo, Y;Gu, D;Huang, T;Li, A;Zhou, Y;Kang, X;Meng, C;Xiong, D;Song, L;Jiao, X;Pan, Z;
PLoS pathogens
Species: Transgenic Mouse, Mouse
Sample Types: Cell Culture Supernates, Serum
-
Targeting IRG1 reverses the immunosuppressive function of tumor-associated macrophages and enhances cancer immunotherapy
Authors: YJ Chen, GN Li, XJ Li, LX Wei, MJ Fu, ZL Cheng, Z Yang, GQ Zhu, XD Wang, C Zhang, JY Zhang, YP Sun, H Saiyin, J Zhang, WR Liu, WW Zhu, KL Guan, Y Xiong, Y Yang, D Ye, LL Chen
Science Advances, 2023-04-28;9(17):eadg0654.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Metabololipidomic and proteomic profiling reveals aberrant macrophage activation and interrelated immunomodulatory mediator release during aging
Authors: P Schädel, A Czapka, N Gebert, ID Jacobsen, A Ori, O Werz
Aging Cell, 2023-04-26;0(0):e13856.
Species: Mouse
Sample Types: Cell Culture Supernates
-
PIMT is a novel and potent suppressor of endothelial activation
Authors: C Zhang, ZF Guo, W Liu, K Kazama, L Hu, X Sun, L Wang, H Lee, L Lu, XF Yang, R Summer, J Sun
Elife, 2023-04-18;12(0):.
Species: Mouse
Sample Types: Bronchoalveolar lavage fluid
-
Collagen-Derived Dipeptides and Amino Acids Have Immunomodulatory Effects in M1-Differentiated RAW264.7 Cells and PBMC
Authors: T Tominaga, J Huang, S Wang, M Noguchi, Y Tong, M Asano-Orit, K Suzuki
International Journal of Molecular Sciences, 2023-04-08;24(8):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Neuroinflammation, Oxidative Stress, Apoptosis, Microgliosis and Astrogliosis in the Cerebellum of Mice Chronically Exposed to Waterpipe Smoke
Authors: Hamadi, N;Beegam, S;Zaaba, NE;Elzaki, O;Altamimi, MA;Nemmar, A;
Biomedicines
Species: Mouse
Sample Types: Tissue Homogenates
-
PYHIN protein IFI207 regulates cytokine transcription and IRF7 and contributes to the establishment of K. pneumoniae infection
Authors: M Baran, C Feriotti, A McGinley, SR Carlile, Z Jiang, R Calderon-G, A Dumigan, J Sá-Pessoa, CE Sutton, J Kearney, RM McLoughlin, KHG Mills, KA Fitzgerald, JA Bengeochea, AG Bowie
Cell Reports, 2023-04-04;42(4):112341.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Induced pluripotent stem cell-derived extracellular vesicles promote wound repair in a diabetic mouse model via an anti-inflammatory immunomodulatory mechanism
Authors: D Levy, SN Abadchi, N Shababi, MR Ravari, NH Pirolli, C Bergeron, A Obiorah, F Mokhtari-E, S Gheshlaghi, JM Abraham, IM Smith, E Powsner, T Solomon, JW Harmon, SM Jay
bioRxiv : the preprint server for biology, 2023-03-23;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Chamomile essential oils exert anti-inflammatory effects involving human and murine macrophages: Evidence to support a therapeutic action
Authors: P De Cicco, G Ercolano, C Sirignano, V Rubino, D Rigano, A Ianaro, C Formisano
Journal of ethnopharmacology, 2023-03-21;0(0):116391.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Mitochondrion-targeted antioxidant SkQ1 prevents rapid animal death caused by highly diverse shocks
Authors: VP Skulachev, MY Vyssokikh, BV Chernyak, OA Averina, AA Andreev-An, RA Zinovkin, KG Lyamzaev, MV Marey, MV Egorov, OJ Frolova, DB Zorov, MV Skulachev, VA Sadovnichi
Scientific Reports, 2023-03-15;13(1):4326.
Species: Human
Sample Types: Plasma
-
Anti-inflammatory effects of Peucedanum japonicum Thunberg leaves extract in Lipopolysaccharide-stimulated RAW264.7�cells
Authors: JH Park, JH Kim, JY Shin, ES Kang, BO Cho
Journal of ethnopharmacology, 2023-03-10;309(0):116362.
Species: Mouse
Sample Types: Cell Lysate
-
Macrophage fumarate hydratase restrains mtRNA-mediated interferon production
Authors: A Hooftman, CG Peace, DG Ryan, EA Day, M Yang, AF McGettrick, M Yin, EN Montano, L Huo, JE Toller-Kaw, V Zecchini, TAJ Ryan, A Bolado-Car, AM Casey, HA Prag, ASH Costa, G De Los San, M Ishimori, DJ Wallace, S Venuturupa, E Nikitopoul, N Frizzell, C Johansson, A Von Kriegs, MP Murphy, C Jefferies, C Frezza, LAJ O'Neill
Nature, 2023-03-08;615(7952):490-498.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Knocking-Down CD147/EMMPRIN Expression in CT26 Colon Carcinoma Forces the Cells into Cellular and Angiogenic Dormancy That Can Be Reversed by Interactions with Macrophages
Authors: G Feigelman, E Simanovich, P Brockmeyer, MA Rahat
Biomedicines, 2023-03-02;11(3):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Oral Cell Lysates Reduce the Inflammatory Response of Activated Macrophages
Authors: L Panahipour, A Oladzad Ab, R Gruber
Journal of Clinical Medicine, 2023-02-20;12(4):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Macrophage-targeted lipid nanoparticle delivery of microRNA-146a to mitigate hemorrhagic shock-induced acute respiratory distress syndrome
Authors: Q Fei, EM Shalosky, R Barnes, VC Shukla, MN Ballinger, L Farkas, RJ Lee, SN Ghadiali, JA Englert
bioRxiv : the preprint server for biology, 2023-02-19;0(0):.
Species: Mouse
Sample Types: BALF
-
Polyphenols with Anti-Inflammatory Properties: Synthesis and Biological Activity of Novel Curcumin Derivatives
Authors: Y González, R Mojica-Flo, D Moreno-Lab, L Cubilla-Ri, KSJ Rao, PL Fernández, OV Larionov, J Lakey-Beit
International Journal of Molecular Sciences, 2023-02-12;24(4):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Periostin deficiency reduces PD-1+ tumor-associated macrophage infiltration and enhances anti-PD-1 efficacy in colorectal cancer
Authors: T Wei, K Wang, S Liu, Y Fang, Z Hong, Y Liu, H Zhang, C Yang, G Ouyang, T Wu
Cell Reports, 2023-02-09;42(2):112090.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Myeloid cells protect corneal nerves against sterile injury through negative-feedback regulation of TLR2-IL-6 axis
Authors: HJ Lee, HJ Kim, JH Ko, JY Oh
Journal of Neuroinflammation, 2023-02-07;20(1):27.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Small molecule inhibiting microglial nitric oxide release could become a potential treatment for neuroinflammation
Authors: P Jordan, A Costa, E Specker, O Popp, A Volkamer, R Piske, T Obrusnik, S Kleissle, K Stuke, A Rex, M Neuenschwa, JP von Kries, M Nazare, P Mertins, H Kettenmann, SA Wolf
PLoS ONE, 2023-02-06;18(2):e0278325.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Characterization of Lipopolysaccharide Effects on LRRK2 Signaling in RAW Macrophages
Authors: A Oun, E Hoeksema, A Soliman, F Brouwer, F García-Rey, H Pots, M Trombetta-, A Kortholt, AM Dolga
International Journal of Molecular Sciences, 2023-01-13;24(2):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
TRPC absence induces pro-inflammatory macrophages and gut microbe disorder, sensitizing mice to colitis
Authors: Y Lin, X Cui, Q Cao, R Bi, Y Liu, D Jing, C Yue, Q Zhao, Y Wang, S Liu, Y Su, K Formoso, S Susperregu, L Birnbaumer, M Freichel, Y Yang, L You, X Gao
International immunopharmacology, 2022-12-31;115(0):109655.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Adipokine C1q/Tumor necrosis factor- Related Protein 3 (CTRP3) Attenuates Intestinal Inflammation via Sirtuin 1 / NF-kappaB Signaling
Authors: H Yu, Z Zhang, G Li, Y Feng, L Xian, F Bakhsh, D Xu, C Xu, T Vong, B Wu, FM Selaru, F Wan, M Donowitz, GW Wong
Cellular and Molecular Gastroenterology and Hepatology, 2022-12-30;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Tryptophan-dependent and -independent secretions of tryptophanyl- tRNA synthetase mediate innate inflammatory responses
Authors: TTT Nguyen, YH Choi, WK Lee, Y Ji, E Chun, YH Kim, JE Lee, HS Jung, JH Suh, S Kim, M Jin
Cell Reports, 2022-12-30;42(1):111905.
Species: Mouse
Sample Types: Lavage Fluid
-
Trypanosoma brucei rhodesiense Inhibitor of Cysteine Peptidase (ICP) Is Required for Virulence in Mice and to Attenuate the Inflammatory Response
Authors: TFR Costa, A Goundry, A Morrot, DJ Grab, JC Mottram, APCA Lima
International Journal of Molecular Sciences, 2022-12-30;24(1):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Dysregulated systemic metabolism in a Down syndrome mouse model
Authors: DC Sarver, C Xu, LM Velez, S Aja, AE Jaffe, MM Seldin, RH Reeves, GW Wong
Molecular Metabolism, 2022-12-29;68(0):101666.
Species: Mouse
Sample Types: Serum
-
Astragaloside IV Targets Macrophages to Alleviate Renal Ischemia-Reperfusion Injury via the Crosstalk between Hif-1alpha and NF-kappaB (p65)/Smad7 Pathways
Authors: L Tang, M Zhu, X Che, X Yang, Y Xu, Q Ma, M Zhang, Z Ni, X Shao, S Mou
Journal of personalized medicine, 2022-12-27;13(1):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Adipose-targeted triiodothyronine therapy counteracts obesity-related metabolic complications and atherosclerosis with negligible side effects
Authors: K Chen, LY Cheong, Y Gao, Y Zhang, T Feng, Q Wang, L Jin, E Honoré, KSL Lam, W Wang, X Hui, A Xu
Nature Communications, 2022-12-20;13(1):7838.
Species: Mouse
Sample Types: Serum
-
EC-18 prevents autoimmune arthritis by suppressing inflammatory cytokines and osteoclastogenesis
Authors: JS Park, SC Yang, HY Jeong, SY Lee, JG Ryu, JW Choi, HY Kang, SM Kim, SH Hwang, ML Cho, SH Park
Arthritis Research & Therapy, 2022-11-17;24(1):254.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Consequences of the Lack of TNFR1 in Ouabain Response in the Hippocampus of C57BL/6J Mice
Authors: PF Kinoshita, AM Orellana, DZ Andreotti, GA de Souza, NP de Mello, L de Sá Lima, EM Kawamoto, C Scavone
Biomedicines, 2022-11-15;10(11):.
Species: Mouse
Sample Types: Serum
-
Involvement of glycoinositolphospholipid from Trypanosoma cruzi and macrophage migration inhibitory factor in proinflammatory mechanisms promoting cardiovascular injury mechanisms promoting cardiovascular inflammation tThe combined action of glycoinositolphospholipid from Trypanosoma cruzi and macrophage migration inhibitory factor increases proinflammatory mediator production by cardiomyocytes and vascular endothelial cells
Authors: CS Rigazio, N Mariz-Pont, EP Caballero, FN Penas, NB Goren, MH Santamaría, RS Corral
Microbial pathogenesis, 2022-11-12;0(0):105881.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Dual Functionalized Liposomes for Selective Delivery of Poorly Soluble Drugs to Inflamed Brain Regions
Authors: S Giofrè, A Renda, S Sesana, B Formicola, B Vergani, BE Leone, V Denti, G Paglia, S Groppuso, V Romeo, L Muzio, A Balboni, A Menegon, A Antoniou, A Amenta, D Passarella, P Seneci, S Pellegrino, F Re
Pharmaceutics, 2022-11-07;14(11):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Postbiotics Prepared Using Lactobacillus paracasei CCFM1224 Prevent Nonalcoholic Fatty Liver Disease by Modulating the Gut Microbiota and Liver Metabolism
Authors: Z Pan, B Mao, Q Zhang, X Tang, B Yang, J Zhao, S Cui, H Zhang
International Journal of Molecular Sciences, 2022-11-04;23(21):.
Species: Mouse
Sample Types: Serum
-
PD-1/PD-L1 inhibition enhances chemotherapy-induced neuropathic pain by suppressing neuroimmune antinociceptive signaling
Authors: CWS Wanderley, A Maganin, B Adjafre, AS Mendes, CE Anibal Sil, AU Quadros, JPM Luiz, CMS Silva, NR Silva, FF Oliveira, FIF Gomes, JLJ Restrepo, CA Speck-Hern, F Turaça, GVL Silva, GR Pigatto, HI Nakaya, JM Mota, R Barroso-So, JC Alves-Filh, TM Cunha, FQ Cunha
Cancer Immunology Research, 2022-11-02;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Combinatorial microRNA Loading into Extracellular Vesicles for Increased Anti-Inflammatory Efficacy
Authors: AE Pottash, D Levy, A Jeyaram, L Kuo, SM Kronstadt, W Chao, SM Jay
Non-coding RNA, 2022-10-21;8(5):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Adipose-Derived Stem Cell Exosomes Inhibit Hypertrophic Scaring Formation by Regulating Th17/Treg Cell Balance
Authors: H Wang, Y Li, Z Yue, Y Liu, Q Chen, D Hu, J Han
BioMed Research International, 2022-10-12;2022(0):9899135.
Species: Mouse
Sample Types: Tissue Homogenates
-
YAP1 protects against septic liver injury via ferroptosis resistance
Authors: J Wang, Q Zhu, R Li, J Zhang, X Ye, X Li
Cell & bioscience, 2022-10-01;12(1):163.
Species: Mouse
Sample Types: Tissue Homogenates
-
Homoharringtonine Attenuates Dextran Sulfate Sodium-Induced Colitis by Inhibiting NF-kappaB Signaling
Authors: J Liu, L Shi, W Huang, Z Zheng, X Huang, Y Su
Mediators of Inflammation, 2022-09-29;2022(0):3441357.
Species: Mouse
Sample Types: Cell Lysates
-
In vivo peptide-based delivery of a gene-modifying enzyme into cells of the central nervous system
Authors: JK Allen, TC Sutherland, AR Prater, CG Geoffroy, JP Pellois
Science Advances, 2022-09-28;8(39):eabo2954.
Species: Mouse
Sample Types: Tissue Homogenates
-
Bone marrow adipocytes drive the development of tissue invasive Ly6Chigh monocytes during obesity
Authors: P Boroumand, DC Prescott, T Mukherjee, PJ Bilan, M Wong, J Shen, I Tattoli, Y Zhou, A Li, T Sivasubram, N Shi, LY Zhu, Z Liu, C Robbins, DJ Philpott, SE Girardin, A Klip
Elife, 2022-09-20;11(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Hypoxia promotes an inflammatory phenotype of fibroblasts in pancreatic cancer
Authors: AM Mello, T Ngodup, Y Lee, KL Donahue, J Li, A Rao, ES Carpenter, HC Crawford, M Pasca di M, KE Lee
Oncogenesis, 2022-09-15;11(1):56.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Extracellular matrix of early pulmonary fibrosis modifies the polarization of alveolar macrophage
Authors: Y Zhang, L Zhu, J Hong, C Chen
International immunopharmacology, 2022-08-24;111(0):109179.
Species: Mouse
Sample Types: Cell Culture Supernates
-
A novel mechanism of regulation of the oncogenic transcription factor GLI3 by toll-like receptor signaling
Authors: SJ Matissek, M Karbalivan, W Han, A Boutilier, E Yzar-Garci, LL Kehoe, DS Gardner, A Hage, K Fleck, V Jeffers, R Rajsbaum, SF Elsawa
Oncotarget, 2022-08-03;13(0):944-959.
Species: Human
Sample Types: Cell Culture Supernates
-
HIF-1alpha induces glycolytic reprograming in tissue-resident alveolar macrophages to promote cell survival during acute lung injury
Authors: PS Woods, LM Kimmig, KA Sun, AY Meliton, OR Shamaa, Y Tian, R Cetin-Atal, WW Sharp, RB Hamanaka, GM Mutlu
Elife, 2022-07-13;11(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Lithocholic acid inhibits dendritic cell activation by reducing intracellular glutathione via TGR5 signaling
Authors: J Hu, Y Zhang, S Yi, C Wang, X Huang, S Pan, J Yang, G Yuan, S Tan, H Li
International journal of biological sciences, 2022-07-11;18(11):4545-4559.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Allergen protease-activated stress granule assembly and gasdermin D fragmentation control interleukin-33 secretion
Authors: W Chen, S Chen, C Yan, Y Zhang, R Zhang, M Chen, S Zhong, W Fan, S Zhu, D Zhang, X Lu, J Zhang, Y Huang, L Zhu, X Li, D Lv, Y Fu, H Iv, Z Ling, L Ma, H Jiang, G Long, J Zhu, D Wu, B Wu, B Sun
Nature Immunology, 2022-07-06;23(7):1021-1030.
Species: Mouse
Sample Types: BALF
-
Artemisinin inhibits neutrophil and macrophage chemotaxis, cytokine production and NET release
Authors: HOJ Morad, S Luqman, LG Pinto, KP Cunningham, B Vilar, G Clayton, M Shankar-Ha, PA McNaughton
Scientific Reports, 2022-06-30;12(1):11078.
Species: Mouse
Sample Types: BALF
-
Synthetic cannabinoids reduce the inflammatory activity of microglia and subsequently improve neuronal survival in vitro
Authors: AP Young, EM Denovan-Wr
Brain, Behavior, and Immunity, 2022-06-25;105(0):29-43.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Neuroprotective effects of ex vivo-expanded regulatory T cells on trimethyltin-induced neurodegeneration in mice
Authors: SY Park, H Yang, M Ye, X Liu, I Shim, YT Chang, H Bae
Journal of Neuroinflammation, 2022-06-11;19(1):143.
Species: Mouse
Sample Types: Serum
-
Sirtuin 1 Induces Choroidal Neovascularization and Triggers Age-Related Macular Degeneration by Promoting LCN2 through SOX9 Deacetylation
Authors: S Zhao, Z Huang, H Jiang, J Xiu, L Zhang, Q Long, Y Yang, L Yu, L Lu, H Gu
Oncogene, 2022-06-09;2022(0):1671438.
Species: Mouse
Sample Types: Tissue Homogenates
-
Acinetobacter quorum sensing contributes to inflammation-induced inhibition of orthopaedic implant osseointegration
Authors: H Choe, BS Hausman, KM Hujer, O Akkus, PN Rather, Z Lee, RA Bonomo, EM Greenfield
Oncogene, 2022-06-09;43(0):267-276.
Species: Mouse
Sample Types: Tissue Homogenates
-
IL-17-producing follicular Th cells enhance plasma cell differentiation in lupus-prone mice
Authors: V Kim, K Lee, H Tian, SH Jang, B Diamond, SJ Kim
JCI Insight, 2022-06-08;7(11):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Asymmetric synthesis of flavanols via Cu-catalyzed kinetic resolution of chromenes and their anti-inflammatory activity
Authors: Q Yang, Z Wang, CHH Hor, H Xiao, Z Bian, JJ Wang
Science Advances, 2022-06-03;8(22):eabm9603.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Polyphenols-Rich Fraction from Annona muricata Linn. Leaves Attenuates Oxidative and Inflammatory Responses in Neutrophils, Macrophages, and Experimental Lung Injury
Authors: AL Saraiva, AB Justino, RR Franco, HCG Silva, FDS Arruda, SG Klein, MRN Celes, LR Goulart, FS Espindola
Pharmaceutics, 2022-05-31;14(6):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
The antioxidant enzyme Peroxiredoxin-1 controls stroke-associated microglia against acute ischemic stroke
Authors: S Kim, W Lee, H Jo, SK Sonn, SJ Jeong, S Seo, J Suh, J Jin, HY Kweon, TK Kim, SH Moon, S Jeon, JW Kim, YR Kim, EW Lee, HK Shin, SH Park, GT Oh
Redox Biology, 2022-05-25;54(0):102347.
Species: Mouse
Sample Types: Serum
-
Neonatal Hypoxic-Ischemic Brain Injury Alters Brain Acylcarnitine Levels in a Mouse Model
Authors: AM Dave, TC Genaro-Mat, Z Korade, ES Peeples
Metabolites, 2022-05-22;12(5):.
Species: Mouse
Sample Types: Tissue Lysates
-
Development of sulfonamide-based NLRP3 inhibitors: Further modifications and optimization through structure-activity relationship studies
Authors: Y Xu, Y Xu, H Blevins, C Guo, S Biby, XY Wang, C Wang, S Zhang
European Journal of Medicinal Chemistry, 2022-05-21;238(0):114468.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Structural characterization of polysaccharides from Geranium sanguineum L. and their immunomodulatory effects in response to inflammatory agents
Authors: YN Georgiev, BM Dzhambazov, TG Batsalova, O Vasicek, LI Dobreva, PN Denev, ST Danova, SD Simova, CW Wold, MH Ognyanov, BS Paulsen, AI Krastanov
Journal of ethnopharmacology, 2022-05-15;0(0):115390.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Influenza virus replication in cardiomyocytes drives heart dysfunction and fibrosis
Authors: AD Kenney, SL Aron, C Gilbert, N Kumar, P Chen, A Eddy, L Zhang, A Zani, N Vargas-Mal, S Speaks, J Kawahara, PJ Denz, L Dorn, F Accornero, J Ma, H Zhu, MVS Rajaram, C Cai, RA Langlois, JS Yount
Science Advances, 2022-05-11;8(19):eabm5371.
Species: Mouse
Sample Types: Tissue Homogenates
-
IL-22 regulates inflammatory responses to agricultural dust-induced airway inflammation
Authors: A Ulu, S Sveiven, A Bilg, JV Velazquez, M Diaz, M Mukherjee, AG Yuil-Valde, S Kota, A Burr, A Najera, TM Nordgren
Toxicology and Applied Pharmacology, 2022-05-05;0(0):116044.
Species: Mouse
Sample Types: BALF
-
Salmonella Enteritidis GalE Protein Inhibits LPS-Induced NLRP3 Inflammasome Activation
Authors: T Huang, D Gu, Y Guo, A Li, X Kang, X Jiao, Z Pan
Microorganisms, 2022-04-26;10(5):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Bladder epithelial cell phosphate transporter inhibition protects mice against uropathogenic Escherichia coli infection
Authors: Y Pang, Z Cheng, S Zhang, S Li, X Li, X Li, X Zhang, X Li, Y Feng, H Cui, Z Chen, L Liu, Q Li, J Huang, M Zhang, S Zhu, L Wang, L Feng
Cell Reports, 2022-04-19;39(3):110698.
Species: Mouse
Sample Types: Serum
-
ADP-ribosylating adjuvant reveals plasticity in cDC1 cells that drive mucosal Th17 cell development and protection against influenza virus infection
Authors: M Arabpour, C Lebrero-Fe, K Schön, A Strömberg, V Börjesson, K Lahl, M Ballegeer, X Saelens, D Angeletti, W Agace, N Lycke
Mucosal Immunology, 2022-04-13;0(0):.
Species: Mouse
Sample Types: Cell Culture Supenates
-
Design and Synthesis of Novel 1,3,4-Oxadiazole and 1,2,4-Triazole Derivatives as Cyclooxygenase-2 Inhibitors with Anti-inflammatory and Antioxidant activity in LPS-stimulated RAW264.7 Macrophages
Authors: MMS Hamoud, NA Osman, S Rezq, H A A Abd El, A E A Hassan, HA Abdel-Fatt, DG Romero, AM Ghanim
Bioorganic chemistry, 2022-04-13;124(0):105808.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Secreted NF-kappaB suppressive microbial metabolites modulate gut inflammation
Authors: R Giri, EC Hoedt, S Khushi, AA Salim, AS Bergot, V Schreiber, R Thomas, MA McGuckin, TH Florin, M Morrison, RJ Capon, P Ó Cuív, J Begun
Cell Reports, 2022-04-12;39(2):110646.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Effects of mango and mint pod-based e-cigarette aerosol inhalation on inflammatory states of the brain, lung, heart, and colon in mice
Authors: A Moshensky, CS Brand, H Alhaddad, J Shin, JA Masso-Silv, I Advani, D Gunge, A Sharma, S Mehta, A Jahan, S Nilaad, J Olay, W Gu, T Simonson, D Almarghala, J Pham, S Perera, K Park, R Al-Kolla, H Moon, S Das, M Byun, Z Shah, Y Sari, J Heller Bro, LE Crotty Ale
Elife, 2022-04-12;11(0):.
Species: Mouse
Sample Types: BALF
-
Candida albicans commensalism in the oral mucosa is favoured by limited virulence and metabolic adaptation
Authors: C Lemberg, K Martinez d, R Fróis-Mart, S Altmeier, VDT Tran, S Mertens, S Amorim-Vaz, LS Rai, C d'Enfert, M Pagni, D Sanglard, S LeibundGut
PloS Pathogens, 2022-04-11;18(4):e1010012.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Aspirin-Triggered Resolvin D1 Reduces Chronic Dust-Induced Lung Pathology without Altering Susceptibility to Dust-Enhanced Carcinogenesis
Authors: EC Dominguez, R Phandthong, M Nguyen, A Ulu, S Guardado, S Sveiven, P Talbot, TM Nordgren
Cancers, 2022-04-09;14(8):.
Species: Mouse
Sample Types: Bronchoalveolar lavage fluid
-
The Secretome of Preconditioned Mesenchymal Stem Cells Drives Polarization and Reprogramming of M2a Macrophages toward an IL-10-Producing Phenotype
Authors: M Holthaus, N Santhakuma, T Wahlers, A Paunel-Gör
International Journal of Molecular Sciences, 2022-04-07;23(8):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Menthone Inhalation Alleviates Local and Systemic Allergic Inflammation in Ovalbumin-Sensitized and Challenged Asthmatic Mice
Authors: YH Su, JY Lin
International Journal of Molecular Sciences, 2022-04-04;23(7):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Cathepsin D interacts with adenosine A2A receptors in mouse macrophages to modulate cell surface localization and inflammatory signaling
Authors: A Skopál, T Kéki, PÁ Tóth, B Csóka, B Koscsó, ZH Német, L Antonioli, A Ivessa, F Ciruela, L Virág, G Haskó, E Kókai
The Journal of Biological Chemistry, 2022-03-31;0(0):101888.
Species: Mouse
Sample Types: Cell Culture Supernates
-
The Mechanism of Pertussis Cough Revealed by the Mouse-Coughing Model
Authors: Y Hiramatsu, K Suzuki, T Nishida, N Onoda, T Satoh, S Akira, M Ikawa, H Ikeda, J Kamei, S Derouiche, M Tominaga, Y Horiguchi
MBio, 2022-03-31;0(0):e0319721.
Species: Mouse
Sample Types: cell culture
-
Reduced expression of mitochondrial complex I subunit Ndufs2 does not impact healthspan in mice
Authors: GS McElroy, RP Chakrabart, KB D'Alessand, K Vasan, J Tan, JS Stoolman, SE Weinberg, EM Steinert, PA Reyfman, BD Singer, WC Ladiges, L Gao, J Lopéz-Barn, GRS Budinger, NS Chandel
Scientific Reports, 2022-03-25;12(1):5196.
Species: Mouse
Sample Types: Serum
-
Sevoflurane Dampens Acute Pulmonary Inflammation via the Adenosine Receptor A2B and Heme Oxygenase-1
Authors: KC Ngamsri, A Fuhr, K Schindler, M Simelitidi, M Hagen, Y Zhang, J Gamper-Tsi, FM Konrad
Cells, 2022-03-24;11(7):.
Species: Mouse
Sample Types: BALF
-
Triglyceride breakdown from lipid droplets regulates the inflammatory response in macrophages
Authors: XAMH van Dieren, F Vrieling, L Smeehuijze, L Deng, JP Boogaard, CA Croes, L Temmerman, S Wetzels, E Biessen, S Kersten, R Stienstra
Proceedings of the National Academy of Sciences of the United States of America, 2022-03-18;119(12):e2114739119.
Species: Mouse
Sample Types: Cell Culture Supernates
-
A Novel Mechanism of Macrophage Activation by the Natural Yolkin Polypeptide Complex from Egg Yolk
Authors: W Kazana, D Jakubczyk, K Pacyga-Pru, K Leszczy?sk, S Górska, J Siednienko, J Maca?a, G Piechowiak, A Zab?ocka
International Journal of Molecular Sciences, 2022-03-14;23(6):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Fetal Tissue-Derived Mast Cells (MC) as Experimental Surrogate for In Vivo Connective Tissue MC
Authors: C Iuliano, M Absmaier-K, T Sinnberg, N Hoffard, M Hils, M Köberle, F Wölbing, E Shumilina, N Heise, B Fehrenbach, M Schaller, F Lang, S Kaesler, T Biedermann
Cells, 2022-03-08;11(6):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Poly epsilon-Caprolactone Nanoparticles for Sustained Intra-Articular Immune Modulation in Adjuvant-Induced Arthritis Rodent Model
Authors: E Singh, RAM Osmani, R Banerjee, AS Abu Lila, A Moin, K Almansour, HH Arab, HF Alotaibi, ES Khafagy
Pharmaceutics, 2022-02-26;14(3):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
The phosphoinositide-3-kinase (PI3K)-delta inhibitor seletalisib impairs monocyte-derived dendritic cells maturation, APC function, and promotes their migration to CCR7 and CXCR4 ligands
Authors: F Scopelliti, L Mercurio, C Cattani, V Dimartino, C Albanesi, G Costanzo, C Mirisola, S Madonna, A Cavani
Journal of leukocyte biology, 2022-02-24;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Inhibition of mitoNEET attenuates LPS-induced inflammation and oxidative stress
Authors: S Lee, BG Seok, SJ Lee, SW Chung
Cell Death & Disease, 2022-02-08;13(2):127.
Species: Mouse
Sample Types: Cell Culture Supernates
-
DDX50 Is a Viral Restriction Factor That Enhances IRF3 Activation
Authors: MA Pallett, Y Lu, GL Smith
Viruses, 2022-02-03;14(2):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Clinical-like cryotherapy in acute knee arthritis of the knee improves inflammation signs, pain, joint swelling, and motor performance in mice
Authors: PATS Castro, GM Barbosa, DH Machanocke, RS Peres, TM Cunha, JE Cunha, FFB Oliveira, FS Ramalho, TL Russo, FQ Cunha, TF Salvini
PLoS ONE, 2022-01-21;17(1):e0261667.
Species: Mouse
Sample Types: Tissue Homogenates
-
C-type lectin receptor CLEC4A2 promotes tissue adaptation of macrophages and protects against atherosclerosis
Authors: I Park, ME Goddard, JE Cole, N Zanin, LP Lyytikäine, T Lehtimäki, E Andreakos, M Feldmann, I Udalova, I Drozdov, C Monaco
Nature Communications, 2022-01-11;13(1):215.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Chemerin Overexpression in the Liver Protects against Inflammation in Experimental Non-Alcoholic Steatohepatitis
Authors: R Pohl, S Feder, EM Haberl, L Rein-Fisch, TS Weiss, M Spirk, A Bruckmann, N McMullen, CJ Sinal, C Buechler
Biomedicines, 2022-01-07;10(1):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
MTMR14 Alleviates Chronic Obstructive Pulmonary Disease as a Regulator in Inflammation and Emphysema
Authors: Y Gu, J Chen, Q Huang, Y Zhan, T Wang, J Wu, J Zhao, Z Zeng, Y Lv, C Xiao, J Xie
Oxidative Medicine and Cellular Longevity, 2022-01-07;2022(0):9300269.
Species: Mouse
Sample Types: BALF
-
The Salutary Effects of Catalpol on Diesel Exhaust Particles-Induced Thrombogenic Changes and Cardiac Oxidative Stress, Inflammation and Apoptosis
Authors: A Nemmar, S Beegam, NE Zaaba, S Alblooshi, S Alseiari, BH Ali
Biomedicines, 2022-01-04;10(1):.
Species: Mouse
Sample Types: Tissue Homogenates
-
IL-2/JES6-1 mAb complexes dramatically increase sensitivity to LPS through IFN-gamma production by CD25+Foxp3- T cells
Authors: J Tomala, P Weberova, B Tomalova, Z Jiraskova, L Sivak, J Kovarova, M Kovar
Elife, 2021-12-21;10(0):.
Species: Mouse
Sample Types: Serum
-
CXCR4 and CXCR7 Inhibition Ameliorates the Formation of Platelet-Neutrophil Complexes and Neutrophil Extracellular Traps through Adora2b Signaling
Authors: KC Ngamsri, RA Putri, C Jans, K Schindler, A Fuhr, Y Zhang, J Gamper-Tsi, S Ehnert, FM Konrad
International Journal of Molecular Sciences, 2021-12-17;22(24):.
Species: Mouse
Sample Types: Plasma
-
Heterocellular OSM-OSMR signalling reprograms fibroblasts to promote pancreatic cancer growth and metastasis
Authors: BY Lee, EKJ Hogg, CR Below, A Kononov, A Blanco-Gom, F Heider, J Xu, C Hutton, X Zhang, T Scheidt, K Beattie, A Lamarca, M McNamara, JW Valle, C Jørgensen
Nature Communications, 2021-12-17;12(1):7336.
Species: Mouse
Sample Types: Tissue Homogenates
-
Hepatocytes are resistant to cell death from canonical and non-canonical inflammasome-activated pyroptosis
Authors: P Sun, J Zhong, H Liao, P Loughran, J Mulla, G Fu, D Tang, J Fan, TR Billiar, W Gao, MJ Scott
Cellular and Molecular Gastroenterology and Hepatology, 2021-12-07;0(0):.
Species: Mouse
Sample Types: Plasma
-
Brain innate immune response via miRNA-TLR7 sensing in polymicrobial sepsis
Authors: L Zou, J He, L Gu, RA Shahror, Y Li, T Cao, S Wang, J Zhu, H Huang, F Chen, X Fan, J Wu, W Chao
Brain, Behavior, and Immunity, 2021-11-19;100(0):10-24.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Cooling and Sterile Inflammation in an Oxygen-Glucose-Deprivation/Reperfusion Injury Model in BV-2 Microglia
Authors: J Lücht, N Rolfs, SJ Wowro, F Berger, KRL Schmitt, G Tong
Mediators of Inflammation, 2021-11-05;2021(0):8906561.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Mitochondrial respiration contributes to the interferon gamma response in antigen-presenting cells
Authors: MC Kiritsy, K McCann, D Mott, SM Holland, SM Behar, CM Sassetti, AJ Olive
Elife, 2021-11-02;10(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
All?trans retinoic acid promotes macrophage phagocytosis and decreases inflammation via inhibiting CD14/TLR4 in acute lung injury
Authors: S Li, Y Lei, J Lei, H Li
Molecular Medicine Reports, 2021-10-22;24(6):.
Species: Mouse
Sample Types: Plasma
-
DRP1-Mediated Mitochondrial Fission Regulates Lung Epithelial Response to Allergen
Authors: SR Bruno, A Kumar, ZF Mark, R Chandrasek, E Nakada, N Chamberlai, B Mihavics, J Walzer, J Cahoon, AE Dixon, B Cunniff, V Anathy
International Journal of Molecular Sciences, 2021-10-15;22(20):.
Species: Mouse
Sample Types: Tissue Homogenates
-
Lung Fibrosis Is Improved by Extracellular Vesicles from IFNgamma-Primed Mesenchymal Stromal Cells in Murine Systemic Sclerosis
Authors: P Rozier, M Maumus, ATJ Maria, K Toupet, C Jorgensen, P Guilpain, D Noël
Cells, 2021-10-13;10(10):.
Species: Mouse
Sample Types: Cell Lysates
-
Sambucus nigra: A traditional medicine effective in reducing inflammation in mice
Authors: JR Santin, L Benvenutti, MF Broering, R Nunes, FC Goldoni, YBK Patel, JA de Souza, MAT Kopp, P de Souza, RCV da Silva, MVD Pastor, AB de Souza, LD Testoni, AG Couto, TMB Bresolin, NLM Quintão
Journal of ethnopharmacology, 2021-10-11;283(0):114736.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Oxidized carbon black nanoparticles induce endothelial damage through C-X-C chemokine receptor 3-mediated pathway
Authors: N Majumder, M Velayutham, D Bitounis, VK Kodali, MH Hasan Mazu, J Amedro, VV Khramtsov, A Erdely, T Nurkiewicz, P Demokritou, EE Kelley, S Hussain
Redox Biology, 2021-10-04;47(0):102161.
Species: Mouse
Sample Types: BALF
-
Limited role of the spleen in a mouse model of trained immunity: Impact on neutrophilia
Authors: AV Ferreira, RF Uijen, O Bulut, MI de Jonge, J Domínguez-, MG Netea
Journal of leukocyte biology, 2021-10-01;0(0):.
Species: Mouse
Sample Types: Serum
-
Coronavirus induces diabetic macrophage-mediated inflammation via SETDB2
Authors: WJ Melvin, CO Audu, FM Davis, SB Sharma, A Joshi, A DenDekker, S Wolf, E Barrett, K Mangum, X Zhou, M Bame, A Ruan, A Obi, SL Kunkel, BB Moore, KA Gallagher
Proceedings of the National Academy of Sciences of the United States of America, 2021-09-21;118(38):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Gut microbiota-mediated secondary bile acids regulate dendritic cells to attenuate autoimmune uveitis through TGR5 signaling
Authors: J Hu, C Wang, X Huang, S Yi, S Pan, Y Zhang, G Yuan, Q Cao, X Ye, H Li
Cell Reports, 2021-09-21;36(12):109726.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Macrophage-derived interleukin-6 is necessary and sufficient for choroidal angiogenesis
Authors: S Droho, CM Cuda, H Perlman, JA Lavine
Scientific Reports, 2021-09-10;11(1):18084.
Species: Mouse, Transgenic Mouse
Sample Types: Tissue Homogenates
-
Drug-peptide supramolecular hydrogel boosting transcorneal permeability and pharmacological activity via ligand-receptor interaction
Authors: L Chen, J Deng, A Yu, Y Hu, B Jin, P Du, J Zhou, L Lei, Y Wang, S Vakal, X Li
Bioactive materials, 2021-09-10;10(0):420-429.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Interleukin-6 actions in the hypothalamus protects against obesity and is involved in the regulation of neurogenesis
Authors: VC Bobbo, DF Engel, CP Jara, NF Mendes, R Haddad-Tov, TP Prado, D Sidarta-Ol, J Morari, LA Velloso, EP Araujo
Journal of Neuroinflammation, 2021-08-31;18(1):192.
Species: Mouse
Sample Types: Plasma
-
Selective Expression of a SNARE-Cleaving Protease in Peripheral Sensory Neurons Attenuates Pain-Related Gene Transcription and Neuropeptide Release
Authors: W Wang, M Kong, Y Dou, S Xue, Y Liu, Y Zhang, W Chen, Y Li, X Dai, J Meng, J Wang
International Journal of Molecular Sciences, 2021-08-17;22(16):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Acute Inflammatory Response in Osteoporotic Fracture Healing Augmented with Mechanical Stimulation is Regulated In Vivo through the p38-MAPK Pathway
Authors: SKH Chow, C Cui, KYK Cheng, YN Chim, J Wang, CHW Wong, KW Ng, RMY Wong, WH Cheung
International Journal of Molecular Sciences, 2021-08-13;22(16):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Oxidant-induced epithelial alarmin pathway mediates lung inflammation and functional decline following ultrafine carbon and ozone inhalation co-exposure
Authors: N Majumder, WT Goldsmith, VK Kodali, M Velayutham, SA Friend, VV Khramtsov, TR Nurkiewicz, A Erdely, PC Zeidler-Er, V Castranova, JR Harkema, EE Kelley, S Hussain
Redox Biology, 2021-08-05;46(0):102092.
Species: Mouse
Sample Types: BALF
-
Mycobacterium tuberculosis inhibits the NLRP3 inflammasome activation via its phosphokinase PknF
Authors: S Rastogi, S Ellinwood, J Augenstrei, KD Mayer-Barb, V Briken
PloS Pathogens, 2021-07-29;17(7):e1009712.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Anti-Inflammatory and Healing Activity of the Hydroalcoholic Fruit Extract of Solanum diploconos (Mart.) Bohs
Authors: L Benvenutti, R Nunes, I Venturi, SA Ramos, MF Broering, FC Goldoni, SE Pavan, MVD Pastor, A Malheiros, NLM Quintão, ES Fernandes, JR Santin
Journal of Immunology Research, 2021-07-19;2021(0):9957451.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Synergistic inhibitory effects of the oxyresveratrol and dacarbazine combination against melanoma cells
Authors: SG Lee, DG Lee, YH Joo, N Chung
Oncology Letters, 2021-07-14;22(3):667.
Species: Mouse
Sample Types: Cell Culture Supernates
-
NLRP3 Triggers Attenuate Lipocalin-2 Expression Independent with Inflammasome Activation
Authors: H Ahn, G Lee, J Kim, J Park, SG Kang, SI Yoon, E Lee, GS Lee
Cells, 2021-07-02;10(7):.
Species: Mouse
Sample Types: Cell Lysates
-
Terminal uridyltransferase 7 regulates TLR4-triggered inflammation by controlling Regnase-1 mRNA uridylation and degradation
Authors: CC Lin, YR Shen, CC Chang, XY Guo, YY Young, TY Lai, IS Yu, CY Lee, TH Chuang, HY Tsai, LC Hsu
Nature Communications, 2021-06-29;12(1):3878.
Species: Mouse
Sample Types: Cell Culture Supernates
-
The role of Sp140 revealed in IgE and mast cell responses in Collaborative Cross mice
Authors: K Matsushita, X Li, Y Nakamura, D Dong, K Mukai, M Tsai, SB Montgomery, SJ Galli
JCI Insight, 2021-06-22;6(12):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Role of the inhibitor of serine peptidase 2 (ISP2) of Trypanosoma brucei rhodesiense in parasite virulence and modulation of the inflammatory responses of the host
Authors: DJ Levy, A Goundry, RSS Laires, TFR Costa, CM Novo, DJ Grab, JC Mottram, APCA Lima
PloS Neglected Tropical Diseases, 2021-06-21;15(6):e0009526.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Serum amyloid P component is an essential element of resistance against Aspergillus fumigatus
Authors: A Doni, R Parente, I Laface, E Magrini, C Cunha, FS Colombo, JF Lacerda, A Campos, SN Mapelli, F Petroni, R Porte, T Schorn, A Inforzato, T Mercier, K Lagrou, J Maertens, JD Lambris, B Bottazzi, C Garlanda, M Botto, A Carvalho, A Mantovani
Nature Communications, 2021-06-18;12(1):3739.
Species: Mouse
Sample Types: Cell Culture Supernates
-
A high docosahexaenoic acid diet alters lung inflammation and recovery following repetitive exposure to aqueous organic dust extracts: Role of DHA in repetitive organic dust exposure
Authors: A Ulu, A Burr, AJ Heires, J Pavlik, T Larsen, PA Perez, C Bravo, NV DiPatrizio, M Baack, DJ Romberger, TM Nordgren
The Journal of nutritional biochemistry, 2021-06-12;0(0):108797.
Species: Mouse
Sample Types: BALF
-
Tumor microenvironmental cytokines bound to cancer exosomes determine uptake by cytokine receptor-expressing cells and biodistribution
Authors: LG Lima, S Ham, H Shin, EPZ Chai, ESH Lek, RJ Lobb, AF Müller, S Mathivanan, B Yeo, Y Choi, BS Parker, A Möller
Nature Communications, 2021-06-10;12(1):3543.
Species: Mouse
Sample Types: Exosomes
-
Nucleotide-binding domain and leucine-rich-repeat-containing protein X1 deficiency induces nicotinamide adenine dinucleotide decline, mechanistic target of rapamycin activation, and cellular senescence and accelerates aging lung-like changes
Authors: HJ Shin, SH Kim, HJ Park, MS Shin, I Kang, MJ Kang
Aging Cell, 2021-06-04;0(0):e13410.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Anti-inflammatory Effects of Empagliflozin and Gemigliptin on LPS-Stimulated Macrophage via the IKK/NF-&kappaB, MKK7/JNK, and JAK2/STAT1 Signalling Pathways
Authors: N Lee, YJ Heo, SE Choi, JY Jeon, SJ Han, DJ Kim, Y Kang, KW Lee, HJ Kim
Journal of Immunology Research, 2021-06-02;2021(0):9944880.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Probiotic and Functional Properties of Limosilactobacillus reuteri INIA P572
Authors: P Diez-Echav, I Martín-Cab, J Garrido-Me, S Langa, T Vezza, JM Landete, L Hidalgo-Ga, F Algieri, MJ Mayer, A Narbad, A García-Laf, M Medina, A Rodríguez-, ME Rodríguez-, J Gálvez, JL Arqués
Nutrients, 2021-05-29;13(6):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
In Vitro Evaluation of the Anti-Inflammatory Effect of KMUP-1 and In Vivo Analysis of Its Therapeutic Potential in Osteoarthritis
Authors: SE Huang, E Sulistyowa, YY Chao, BN Wu, ZK Dai, JH Hsu, JL Yeh
Biomedicines, 2021-05-28;9(6):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
d-enantiomers of CATH-2 enhance the response of macrophages against Streptococcus suis serotype 2
Authors: RM van Harten, JLM Tjeerdsma-, A de Greeff, MD Balhuizen, A van Dijk, EJA Veldhuizen, HP Haagsman, MR Scheenstra
Journal of advanced research, 2021-05-26;36(0):101-112.
Species: Mouse
Sample Types: Cell Culture Supernates
-
DA-DRD5 signaling controls colitis by regulating colonic M1/M2 macrophage polarization
Authors: L Liu, Y Wu, B Wang, Y Jiang, L Lin, X Li, S Yang
Cell Death & Disease, 2021-05-17;12(6):500.
Species: Mouse
Sample Types: Cell Culture Supernates
-
The Adjuvants Polyphosphazene (PCEP) and a Combination of Curdlan Plus Leptin Promote a Th17-Type Immune Response to an Intramuscular Vaccine in Mice
Authors: A Chaffey, G Hamonic, D Chand, GK Mutwiri, HL Wilson
Vaccines, 2021-05-14;9(5):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Studies of involvement of G-protein coupled receptor-3 in cannabidiol effects on inflammatory responses of mouse primary astrocytes and microglia
Authors: J Wu, N Chen, Y Liu, G Godlewski, HJ Kaplan, SH Shrader, ZH Song, H Shao
PLoS ONE, 2021-05-13;16(5):e0251677.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Resveratrol-Loaded Lipid-Core Nanocapsules Modulate Acute Lung Inflammation and Oxidative Imbalance Induced by LPS in Mice
Authors: MTP de Oliveir, DS Coutinho, SS Guterres, AR Pohlmann, PMRE Silva, MA Martins, A Bernardi
Pharmaceutics, 2021-05-10;13(5):.
Species: Mouse
Sample Types: Tissue Homogenates
-
Novel 1,2,4-triazine-quinoline hybrids: The privileged scaffolds as potent multi-target inhibitors of LPS-induced inflammatory response via dual COX-2 and 15-LOX inhibition
Authors: AM Ghanim, S Rezq, TS Ibrahim, DG Romero, H Kothayer
European Journal of Medicinal Chemistry, 2021-04-20;219(0):113457.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Thymoquinone, a Dietary Bioactive Compound, Exerts Anti-Inflammatory Effects in Colitis by Stimulating Expression of the Colonic Epithelial PPAR-&gamma Transcription Factor
Authors: B Venkataram, S Almarzooqi, V Raj, AT Alhassani, AS Alhassani, KJ Ahmed, VS Subramania, SK Ojha, S Attoub, TE Adrian, SB Subramanya
Nutrients, 2021-04-17;13(4):.
Species: Mouse
Sample Types: Tissue Homogenates
-
Hydroxyapatite-Coated SPIONs and Their Influence on Cytokine Release
Authors: B Friedrich, JP Auger, S Dutz, I Cicha, E Schreiber, J Band, AR Boccacccin, G Krönke, C Alexiou, R Tietze
International Journal of Molecular Sciences, 2021-04-16;22(8):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
A NOVEL NOX/PHOX-CD38-NAADP-TFEB AXIS IMPORTANT FOR MACROPHAGE ACTIVATION DURING BACTERIAL PHAGOCYTOSIS
Authors: M Najibi, HH Honwad, JA Moreau, SM Becker, JE Irazoqui
Autophagy, 2021-04-13;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Generation and utilization of a HEK-293T murine GM-CSF expressing cell line
Authors: EK Robinson, S Covarrubia, S Zhou, S Carpenter
PLoS ONE, 2021-04-09;16(4):e0249117.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Exploiting pyocyanin to treat mitochondrial disease due to respiratory complex III dysfunction
Authors: R Peruzzo, S Corrà, R Costa, M Brischigli, T Varanita, L Biasutto, C Rampazzo, D Ghezzi, L Leanza, M Zoratti, M Zeviani, C De Pittà, C Viscomi, R Costa, I Szabò
Nature Communications, 2021-04-08;12(1):2103.
Species: Mouse
Sample Types: Plasma
-
PDE9 Inhibitor PF-04447943 Attenuates DSS-Induced Colitis by Suppressing Oxidative Stress, Inflammation, and Regulating T-Cell Polarization
Authors: MN Rana, J Lu, E Xue, J Ruan, Y Liu, L Zhang, R Dhar, Y Li, Z Hu, J Zhou, W Ma, H Tang
Frontiers in Pharmacology, 2021-04-08;12(0):643215.
Species: Mouse
Sample Types: Tissue Homogenates
-
The anti-inflammatory cytokine interleukin-37 is an inhibitor of trained immunity
Authors: G Cavalli, IW Tengesdal, M Gresnigt, T Nemkov, RJW Arts, J Domínguez-, R Molteni, D Stefanoni, E Cantoni, L Cassina, S Giugliano, K Schraa, TS Mills, EM Pietras, EZ Eisenmenss, L Dagna, A Boletta, A D'Alessand, LAB Joosten, MG Netea, CA Dinarello
Cell Reports, 2021-04-06;35(1):108955.
Species: Mouse
Sample Types: Tissue Homogenates
-
Cryptococcus gattii evades CD11b-mediated fungal recognition by coating itself with capsular polysaccharides
Authors: K Ueno, Y Otani, N Yanagihara, M Urai, A Nagamori, M Sato-Fukus, K Shimizu, N Saito, Y Miyazaki
European Journal of Immunology, 2021-03-30;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Water-soluble polysaccharides from Pleurotus eryngii fruiting bodies, their activity and affinity for Toll-like receptor 2 and dectin-1
Authors: CF Ellefsen, CW Wold, AL Wilkins, F Rise, ABC Samuelsen
Carbohydrate polymers, 2021-03-26;264(0):117991.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Hepatoprotective Effect of Mixture of Dipropyl Polysulfides in Concanavalin A-Induced Hepatitis
Authors: D Arsenijevi, B Stojanovic, J Milovanovi, A Arsenijevi, M Simic, M Pergal, I Kodranov, O Cvetkovic, D Vojvodic, E Ristanovic, D Manojlovic, M Milovanovi, N Arsenijevi
Nutrients, 2021-03-22;13(3):.
Species: Mouse
Sample Types: Tissue Homogenates
-
Bifidobacterium adolescentis Isolated from Different Hosts Modifies the Intestinal Microbiota and Displays Differential Metabolic and Immunomodulatory Properties in Mice Fed a High-Fat Diet
Authors: B Wang, Q Kong, S Cui, X Li, Z Gu, J Zhao, H Zhang, W Chen, G Wang
Nutrients, 2021-03-21;13(3):.
Species: Mouse
Sample Types: Tissue Homogenates
-
Encapsulation of a CpG oligonucleotide in cationic liposomes enhances its local antitumor activity following pulmonary delivery in a murine model of metastatic lung cancer
Authors: C Loira-Past, K Vanvarenbe, B Ucakar, M Machado Fr, A Staub, M Lemaire, JC Renauld, R Vanbever
International journal of pharmaceutics, 2021-03-19;600(0):120504.
Species: Mouse
Sample Types: Serum
-
Aryl hydrocarbon receptor (Ahr)-dependent Il-22 expression by type 3 innate lymphoid cells control of acute joint inflammation
Authors: R Nehmar, L Fauconnier, J Alves-Filh, D Togbe, A DeCauwer, S Bahram, M Le Bert, B Ryffel, P Georgel
Journal of Cellular and Molecular Medicine, 2021-03-18;0(0):.
Species: Mouse
Sample Types: Tissue Homogenates
-
&alpha-Phellandrene exhibits antinociceptive and tumor-reducing effects in a mouse model of oncologic pain
Authors: FR Pinheiro-N, EM Lopes, BT Acha, LDS Gomes, WA Dias, ACD Reis Filho, BS Leal, DCDN Rodrigues, JDN Silva, D Dittz, PMP Ferreira, FRC Almeida
Toxicology and Applied Pharmacology, 2021-03-17;418(0):115497.
Species: Mouse
Sample Types: Serum
-
Remote effects and biodistribution of pulmonary instilled silver nanoparticles in mice
Authors: Z Ferdous, S Al-Salam, P Yuvaraju, BH Ali, A Nemmar
NanoImpact, 2021-03-13;22(0):100310.
Species: Mouse
Sample Types: Tissue Homogenates
-
Itaconate confers tolerance to late NLRP3 inflammasome activation
Authors: M Bambouskov, L Potuckova, T Paulenda, M Kerndl, DA Mogilenko, K Lizotte, A Swain, S Hayes, RD Sheldon, H Kim, U Kapadnis, AE Ellis, C Isaguirre, S Burdess, A Laha, GK Amarasingh, V Chubukov, TP Roddy, MS Diamond, RG Jones, DM Simons, MN Artyomov
Cell Reports, 2021-03-09;34(10):108756.
Species: Mouse
Sample Types: Peritoneal Fluid
-
Silicone Oil-Based Nanoadjuvants as Candidates for a New Formulation of Intranasal Vaccines
Authors: A Razim, M Pyclik, K Pacyga, S Górska, J Xu, MA Olszewski, A Gamian, A Myc
Vaccines, 2021-03-08;9(3):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Mitochondrial arginase-2 is essential for IL-10 metabolic reprogramming of inflammatory macrophages
Authors: JK Dowling, R Afzal, LJ Gearing, MP Cervantes-, S Annett, GM Davis, C De Santi, N Assmann, K Dettmer, DJ Gough, GR Bantug, FI Hamid, FK Nally, CP Duffy, AL Gorman, AM Liddicoat, EC Lavelle, C Hess, PJ Oefner, DK Finlay, GP Davey, T Robson, AM Curtis, PJ Hertzog, BRG Williams, CE McCoy
Nature Communications, 2021-03-05;12(1):1460.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Small Immunomodulatory Molecules as Potential Therapeutics in Experimental Murine Models of Acute Lung Injury (ALI)/Acute Respiratory Distress Syndrome (ARDS)
Authors: D Shah, P Das, S Acharya, B Agarwal, DJ Christense, SM Robertson, V Bhandari
International Journal of Molecular Sciences, 2021-03-04;22(5):.
Species: Mouse
Sample Types: BALF
-
Physalis angulata reduces the progression of chronic experimental periodontitis by immunomodulatory mechanisms
Authors: PS Vieceli, PJ Lima Juiz, PS Sales Laur, RD Couto, TC Barbosa To, IM Ribeiro, MB Pereira So, CF Villarreal
Journal of ethnopharmacology, 2021-03-03;0(0):113986.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Inflammatory, synaptic, motor, and behavioral alterations induced by gestational sepsis on the offspring at different stages of life
Authors: MG Granja, LP Alves, M Leardini-T, ME Saul, LC Bortoni, FM de Moraes, EC Ferreira, BPT de Moraes, VZ da Silva, AFR Dos Santos, AR Silva, CF Gonçalves-, V Bambini-Ju, AS Weyrich, MT Rondina, GA Zimmerman, HC de Castro-
Journal of Neuroinflammation, 2021-02-25;18(1):60.
Species: Mouse
Sample Types: Tissue Homogenates
-
Niclosamide suppresses the expansion of follicular helper T cells and alleviates disease severity in two murine models of lupus via STAT3
Authors: SG Jang, J Lee, SM Hong, YS Song, MJ Kim, SK Kwok, ML Cho, SH Park
Journal of Translational Medicine, 2021-02-25;19(1):86.
Species: Mouse
Sample Types: Serum
-
Inflammation promotes adipocyte lipolysis via IRE1 kinase
Authors: KP Foley, Y Chen, NG Barra, M Heal, K Kwok, AK Tamrakar, W Chi, BM Duggan, BD Henriksbo, Y Liu, JD Schertzer
The Journal of Biological Chemistry, 2021-02-19;0(0):100440.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Anti-Inflammatory Effects of Antarctic Lichen Umbilicaria antarctica Methanol Extract in Lipopolysaccharide-Stimulated RAW 264.7 Macrophage Cells and Zebrafish Model
Authors: JM Hong, JE Kim, SK Min, KH Kim, SJ Han, JH Yim, H Park, JH Kim, IC Kim
BioMed Research International, 2021-02-16;2021(0):8812090.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Gymnema inodorum (Lour.) Decne. Extract Alleviates Oxidative Stress and Inflammatory Mediators Produced by RAW264.7 Macrophages
Authors: B Dunkhuntho, C Talabnin, M Murphy, K Thumanu, P Sittisart, G Eumkeb
Oxidative Medicine and Cellular Longevity, 2021-02-04;2021(0):8658314.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Oxygen conditions oscillating between hypoxia and hyperoxia induce different effects in the pulmonary endothelium compared to constant oxygen conditions
Authors: P Wohlrab, M Johann Dan, W Schaubmayr, A Tiboldi, K Krenn, K Markstalle, R Ullrich, K Ulrich Kle, V Tretter
Physiological Reports, 2021-02-01;9(3):e14590.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Dual Role of Interleukin-10 in Murine NZB/W F1 Lupus
Authors: A Amend, N Wickli, AL Schäfer, DTL Sprenger, RA Manz, RE Voll, N Chevalier
International Journal of Molecular Sciences, 2021-01-29;22(3):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
AIM2 in regulatory T cells restrains autoimmune diseases
Authors: WC Chou, Z Guo, H Guo, L Chen, G Zhang, K Liang, L Xie, X Tan, SA Gibson, E Rampanelli, Y Wang, SA Montgomery, WJ Brickey, M Deng, L Freeman, S Zhang, MA Su, X Chen, YY Wan, JP Ting
Nature, 2021-01-27;0(0):.
Species: Mouse, Transgenic Mouse
Sample Types: Tissue Homogenates
-
Hypoxia-Induced S100A8 Expression Activates Microglial Inflammation and Promotes Neuronal Apoptosis
Authors: JS Ha, HR Choi, IS Kim, EA Kim, SW Cho, SJ Yang
International Journal of Molecular Sciences, 2021-01-26;22(3):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Gasdermin D restricts Burkholderia cenocepacia infection in vitro and in vivo
Authors: S Estfanous, K Krause, MNK Anne, M Eltobgy, K Caution, A Abu Khweek, K Hamilton, A Badr, K Daily, C Carafice, D Baetzhold, X Zhang, T Li, H Wen, MA Gavrilin, H Haffez, S Soror, AO Amer
Scientific Reports, 2021-01-13;11(1):855.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Nanoparticle delivery of microRNA-146a regulates mechanotransduction in lung macrophages and mitigates injury during mechanical ventilation
Authors: CM Bobba, Q Fei, V Shukla, H Lee, P Patel, RK Putman, C Spitzer, M Tsai, MD Wewers, RJ Lee, JW Christman, MN Ballinger, SN Ghadiali, JA Englert
Nature Communications, 2021-01-12;12(1):289.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Protein Digests and Pure Peptides from Chia Seed Prevented Adipogenesis and Inflammation by Inhibiting PPAR&gamma and NF-&kappaB Pathways in 3T3L-1 Adipocytes
Authors: M Grancieri, HSD Martino, E Gonzalez d
Nutrients, 2021-01-08;13(1):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Severity of Experimental Autoimmune Uveitis Is Reduced by Pretreatment with Live Probiotic Escherichia coli Nissle 1917
Authors: O Dusek, A Fajstova, A Klimova, P Svozilkova, T Hrncir, M Kverka, S Coufal, J Slemin, H Tlaskalova, JV Forrester, J Heissigero
Cells, 2020-12-25;10(1):.
Species: Mouse
Sample Types: Tissue Culture Supernates
-
Diet Rich in Simple Sugars Promotes Pro-Inflammatory Response via Gut Microbiota Alteration and TLR4 Signaling
Authors: A Fajstova, N Galanova, S Coufal, J Malkova, M Kostovcik, M Cermakova, H Pelantova, M Kuzma, B Sediva, T Hudcovic, T Hrncir, H Tlaskalova, M Kverka, K Kostovciko
Cells, 2020-12-16;9(12):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
TXNIP Regulates Natural Killer Cell-Mediated Innate Immunity by Inhibiting IFN-&gamma Production during Bacterial Infection
Authors: DO Kim, JE Byun, WS Kim, MJ Kim, JH Choi, H Kim, E Choi, TD Kim, SR Yoon, JY Noh, YJ Park, J Lee, HJ Cho, HG Lee, SH Min, I Choi, H Jung
International Journal of Molecular Sciences, 2020-12-14;21(24):.
Species: Mouse
Sample Types: Serum
-
Active food ingredients production from cold pressed processing residues of Camellia oleifera and Camellia sinensis seeds for regulation of blood pressure and vascular function
Authors: SS Chiang, LS Chen, CY Chu
Chemosphere, 2020-12-11;267(0):129267.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Ubiquitination of RIPK1 regulates its activation mediated by TNFR1 and TLRs signaling in distinct manners
Authors: X Li, M Zhang, X Huang, W Liang, G Li, X Lu, Y Li, H Pan, L Shi, H Zhu, L Qian, B Shan, J Yuan
Nature Communications, 2020-12-11;11(1):6364.
Species: Mouse
Sample Types: Serum
-
Dapagliflozin Does Not Modulate Atherosclerosis in Mice with Insulin Resistance
Authors: A Taberner-C, Á Vinué, A Herrero-Ce, M Aguilar-Ba, JT Real, DJ Burks, S Martínez-H, H González-N
International Journal of Molecular Sciences, 2020-12-03;21(23):.
Species: Mouse
Sample Types: Plasma
-
IL-33 Mediates Lung Inflammation by the IL-6-Type Cytokine Oncostatin M
Authors: F Botelho, A Dubey, EA Ayaub, R Park, A Yip, A Humbles, R Kolbeck, CD Richards
Mediators of Inflammation, 2020-11-28;2020(0):4087315.
Species: Mouse
Sample Types: BALF
-
Olive Leaf Extract, from Olea europaea L., Reduces Palmitate-Induced Inflammation via Regulation of Murine Macrophages Polarization
Authors: P De Cicco, M Maisto, GC Tenore, A Ianaro
Nutrients, 2020-11-28;12(12):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Dual chemotherapy with benznidazole at suboptimal dose plus curcumin nanoparticles mitigates Trypanosoma cruzi-elicited chronic cardiomyopathy
Authors: M Hernández, S Wicz, E Pérez Caba, MH Santamaría, RS Corral
Parasitol Int, 2020-11-22;81(0):102248.
Species: Mouse
Sample Types: Tissue Homogenates
-
Structural insights into loss of function of a pore forming toxin and its role in pneumococcal adaptation to an intracellular lifestyle
Authors: DC Badgujar, A Anil, AE Green, MV Surve, S Madhavan, A Beckett, IA Prior, BK Godsora, SB Patil, PK More, SG Sarkar, A Mitchell, R Banerjee, PS Phale, TJ Mitchell, DR Neill, P Bhaumik, A Banerjee
PloS Pathogens, 2020-11-20;16(11):e1009016.
Species: Mouse
Sample Types: Tissue Homogenates
-
Different experimental multiple trauma models induce comparable inflammation and organ injury
Authors: B Relja, B Yang, K Bundkirche, B Xu, K Köhler, C Neunaber
Sci Rep, 2020-11-19;10(1):20185.
Species: Mouse
Sample Types: Plasma
-
Disrupting Bordetella Immunosuppression Reveals a Role for Eosinophils in Coordinating the Adaptive Immune Response in the Respiratory Tract
Authors: MC Gestal, U Blas-Macha, HM Johnson, LN Rubin, KK Dewan, C Bryant, M Tiemeyer, ET Harvill
Microorganisms, 2020-11-17;8(11):.
Species: Mouse
Sample Types: Tissue Homogenates
-
Anti-Axl antibody treatment reduces the severity of experimental autoimmune encephalomyelitis
Authors: JC DuBois, AK Ray, P Davies, B Shafit-Zag
J Neuroinflammation, 2020-10-29;17(1):324.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Human recombinant interleukin-38 suppresses inflammation in mouse models of local and systemic disease
Authors: DM de Graaf, RJA Maas, SP Smeekens, E Eisenmesse, JS Redzic, MM Helsen, NE Powers, S Li, V Kalabokis, MS Gresnigt, LAB Joosten, CA Dinarello, FL van de Vee
Cytokine, 2020-10-28;137(0):155334.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Lactococcus lactis subsp. Cremoris C60 restores T Cell Population in Small Intestinal Lamina Propria in Aged Interleukin-18 Deficient Mice
Authors: S Saito, N Kakizaki, A Okuno, T Maekawa, NM Tsuji
Nutrients, 2020-10-27;12(11):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Repeated dermal application of the common preservative methylisothiazolinone triggers local inflammation, T cell influx, and prolonged mast cell-dependent tactile sensitivity in mice
Authors: JM Kline, E Arriaga-Go, T Yangdon, B Boo, J Landry, M Saldías-Mo, N Neamonitak, H Mengistu, S Silverio, H Zacheis, D Pasha, T Martinov, BT Fife, D Chatterjea
PLoS ONE, 2020-10-26;15(10):e0241218.
Species: Mouse
Sample Types: Cell Lysates
-
Neuroinflammaging underlies emotional disturbances and circadian rhythm disruption in young male senescence-accelerated mouse prone 8 mice
Authors: N Ito, H Takemoto, A Hasegawa, C Sugiyama, K Honma, T Nagai, Y Kobayashi, H Odaguchi
Exp Gerontol, 2020-10-16;0(0):111109.
Species: Mouse
Sample Types: Serum
-
Simvastatin Posttreatment Controls Inflammation and Improves Bacterial Clearance in Experimental Sepsis
Authors: FM de Jesus O, CF Gonçalves-, IMM de Moraes, PA Reis, VN Rocha, PT Bozza, AR Silva, HC de Castro
Mediators Inflamm, 2020-10-14;2020(0):1839762.
Species: Mouse
Sample Types: Cell Culture Supernates
-
The overexpression of TDP-43 in astrocytes causes neurodegeneration via a PTP1B-mediated inflammatory response
Authors: S Lee, S Kim, HY Kang, HR Lim, Y Kwon, M Jo, YM Jeon, SR Kim, K Kim, CM Ha, S Lee, HJ Kim
J Neuroinflammation, 2020-10-14;17(1):299.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Staphylococcus aureus-Derived &alpha-Hemolysin Evokes Generation of Specialized Pro-resolving Mediators Promoting Inflammation Resolution
Authors: PM Jordan, J Gerstmeier, S Pace, R Bilancia, Z Rao, F Börner, L Miek, Ó Gutiérrez-, V Arakandy, A Rossi, A Ialenti, C González-E, B Löffler, L Tuchscherr, CN Serhan, O Werz
Cell Rep, 2020-10-13;33(2):108247.
Species: Mouse
Sample Types: Cell Culture Supernates
-
The Pseudomonas aeruginosa protease LasB directly activates IL-1&beta
Authors: J Sun, DL LaRock, EA Skowronski, JM Kimmey, J Olson, Z Jiang, AJ O'Donoghue, V Nizet, CN LaRock
EBioMedicine, 2020-09-23;60(0):102984.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Phoenixin 14 Inhibits High-Fat Diet-Induced Non-Alcoholic Fatty Liver Disease in Experimental Mice
Authors: F Yang, P Huang, L Shi, F Liu, A Tang, S Xu
Drug Des Devel Ther, 2020-09-22;14(0):3865-3874.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Th17/Treg imbalance in COPD development: suppressors of cytokine signaling and signal transducers and activators of transcription proteins
Authors: LEF Silva, JD Lourenço, KR Silva, FPR Santana, JB Kohler, AR Moreira, APP Velosa, CM Prado, RP Vieira, MV Aun, IFLC Tibério, JT Ito, FDTQS Lopes
Scientific Reports, 2020-09-17;10(1):15287.
Species: Mouse
Sample Types: Tissue Homogenates
-
In Vitro Characterization of Gut Microbiota-Derived Commensal Strains: Selection of Parabacteroides distasonis Strains Alleviating TNBS-Induced Colitis in Mice
Authors: B Cuffaro, ALW Assohoun, D Boutillier, L Súkeníková, J Desramaut, S Boudebbouz, S Salomé-Des, J Hrdý, AJ Waligora-D, E Maguin, C Grangette
Cells, 2020-09-16;9(9):.
Species: Mouse
Sample Types: Serum
-
Deficiency of peroxiredoxin 2 exacerbates angiotensin II-induced abdominal aortic aneurysm
Authors: SJ Jeong, MJ Cho, NY Ko, S Kim, IH Jung, JK Min, SH Lee, JG Park, GT Oh
Exp. Mol. Med., 2020-09-14;0(0):.
Species: Mouse
Sample Types: Cell Lysates
-
Standardized herbal extract PM014 alleviates fine dust-induced lung inflammation in mice
Authors: YS Lee, D Min, SY Park, J Lee, H Bae
BMC Complement Med Ther, 2020-09-07;20(1):270.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Isolation of Two Novel Human Anti-CTLA-4 mAbs with Intriguing Biological Properties on Tumor and NK Cells
Authors: M Passariell, C Vetrei, E Sasso, G Froechlich, C Gentile, AM D'Alise, N Zambrano, E Scarselli, A Nicosia, C De Lorenzo
Cancers (Basel), 2020-08-06;12(8):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Methyl-donor supplementation prevents intestinal colonization by Adherent-Invasive E. coli in a mouse model of Crohn's disease
Authors: E Gimier, M Chervy, A Agus, A Sivignon, E Billard, M Privat, S Viala, R Minet-Quin, A Buisson, E Vazeille, N Barnich, J Denizot
Sci Rep, 2020-07-31;10(1):12922.
Species: Mouse
Sample Types: Cell Culture Supernates, Tissue Homogenates
-
STAT3 serine phosphorylation is required for TLR4 metabolic reprogramming and IL-1&beta expression
Authors: JJ Balic, H Albargy, K Luu, FJ Kirby, WSN Jayasekara, F Mansell, DJ Garama, D De Nardo, N Baschuk, C Louis, F Humphries, K Fitzgerald, E Latz, DJ Gough, A Mansell
Nat Commun, 2020-07-30;11(1):3816.
Species: Mouse
Sample Types: Cell Lysates
-
Preconditioning mesenchymal stromal cells with flagellin enhances the anti?inflammatory ability of their secretome against lipopolysaccharide?induced acute lung injury
Authors: R Li, Y Li, X Dong
Molecular Medicine Reports, 2020-07-28;0(0):.
Species: Mouse
Sample Types: BALF
-
Essential role of Salmonella Enteritidis DNA adenine methylase in modulating inflammasome activation
Authors: Y Guo, D Gu, T Huang, L Cao, X Zhu, Y Zhou, K Wang, X Kang, C Meng, X Jiao, Z Pan
BMC Microbiol., 2020-07-28;20(1):226.
Species: Mouse
Sample Types: Cell Culture Supernates
-
MG53 suppresses interferon-&beta and inflammation via regulation of ryanodine receptor-mediated intracellular calcium signaling
Authors: M Sermershei, AD Kenney, PH Lin, TM McMichael, C Cai, K Gumpper, TMA Adesanya, H Li, X Zhou, KH Park, JS Yount, J Ma
Nat Commun, 2020-07-17;11(1):3624.
Species: Human
Sample Types: Cell Culture Supernates
-
Tofacitinib treatment aggravates Staphylococcus aureus septic arthritis, but attenuates sepsis and enterotoxin induced shock in mice
Authors: A Jarneborn, M Mohammad, C Engdahl, Z Hu, M Na, A Ali, T Jin
Sci Rep, 2020-07-02;10(1):10891.
Species: Mouse
Sample Types: Serum
-
Skeletal muscle antagonizes antiviral CD8+ T cell exhaustion
Authors: J Wu, N Weisshaar, A Hotz-Wagen, A Madi, S Ma, A Mieg, M Hering, K Mohr, T Schlimbach, H Borgers, G Cui
Sci Adv, 2020-06-12;6(24):eaba3458.
Species: Mouse
Sample Types: Serum
-
TRPM5 Negatively Regulates Calcium-Dependent Responses in Lipopolysaccharide-Stimulated B Lymphocytes
Authors: T Sakaguchi, R Okumura, C Ono, D Okuzaki, T Kawai, Y Okochi, N Tanimura, M Murakami, H Kayama, E Umemoto, H Kioka, T Ohtani, Y Sakata, K Miyake, Y Okamura, Y Baba, K Takeda
Cell Rep, 2020-06-09;31(10):107755.
Species: Mouse
Sample Types: Serum
-
Development of insulin resistance preceded major changes in iron homeostasis in mice fed a high-fat diet
Authors: J Varghese, JV James, R Anand, M Narayanasa, G Rebekah, B Ramakrishn, AJ Nellickal, M Jacob
J. Nutr. Biochem., 2020-06-02;84(0):108441.
Species: Mouse
Sample Types: Serum
-
The TSPO-NOX1 axis controls phagocyte-triggered pathological angiogenesis in the eye
Authors: A Wolf, M Herb, M Schramm, T Langmann
Nat Commun, 2020-06-01;11(1):2709.
Species: Mouse
Sample Types: Tissue Homogenates
-
Intracellular ROS Scavenging and Anti-Inflammatory Activities of Oroxylum indicum Kurz (L.) Extract in LPS plus IFN-gamma-Activated RAW264.7 Macrophages
Authors: B Dunkhuntho, C Talabnin, M Murphy, K Thumanu, P Sittisart, T Hengpratom, G Eumkeb
Evid Based Complement Alternat Med, 2020-05-27;2020(0):7436920.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Strain-Specific Differences in House Dust Mite (Dermatophagoides farinae)-Induced Mouse Models of Allergic Rhinitis
Authors: KI Lee, JS Bae, EH Kim, JH Kim, L Lyu, YJ Chung, JH Mo
Clin Exp Otorhinolaryngol, 2020-05-15;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
The role of Staphylococcus aureus lipoproteins in hematogenous septic arthritis
Authors: M Mohammad, Z Hu, A Ali, PK Kopparapu, M Na, A Jarneborn, MDN Stroparo, MT Nguyen, A Karlsson, F Götz, R Pullerits, T Jin
Sci Rep, 2020-05-13;10(1):7936.
Species: Mouse
Sample Types: Serum
-
The Bioinformatic and In Vitro Studies of Clostridioides Difficile Aminopeptidase M24 Revealed the Immunoreactive KKGIK Peptide
Authors: K Pacyga, A Razim, G Martirosia, M Aptekorz, A Szuba, A Gamian, A Myc, S Górska
Cells, 2020-05-07;9(5):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Distinct iron homeostasis in C57BL/6 and Balb/c mouse strains
Authors: P Saha, X Xiao, Y Li, RM Golonka, AA Abokor, BS Yeoh, M Vijay-Kuma
Physiol Rep, 2020-05-01;8(9):e14441.
Species: Mouse
Sample Types: Serum
-
FUT1 deficiency elicits immune dysregulation and corneal opacity in steady state and under stress
Authors: KW Kim, JS Ryu, JH Ko, JY Kim, HJ Kim, HJ Lee, JH Oh, JH Chung, JY Oh
Cell Death Dis, 2020-04-24;11(4):285.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Endogenous itaconate is not required for particulate matter-induced NRF2 expression or inflammatory response
Authors: KA Sun, Y Li, AY Meliton, PS Woods, LM Kimmig, R Cetin-Atal, RB Hamanaka, GM Mutlu
Elife, 2020-04-07;9(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
M1 Polarization but Anti-LPS-Induced Inflammation and Anti-MCF-7 Breast Cancer Cell Growth Effects of Five Selected Polysaccharides
Authors: HC Lin, JY Lin
Evid Based Complement Alternat Med, 2020-03-25;2020(0):9450246.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Bordetella Dermonecrotic Toxin Is a Neurotropic Virulence Factor That Uses CaV3.1 as the Cell Surface Receptor
Authors: S Teruya, Y Hiramatsu, K Nakamura, A Fukui-Miya, K Tsukamoto, N Shinoda, D Motooka, S Nakamura, K Ishigaki, N Shinzawa, T Nishida, F Sugihara, Y Maeda, Y Horiguchi
MBio, 2020-03-24;11(2):.
Species: Mouse
Sample Types: CSF
-
Calcitriol Prevents Neuroinflammation and Reduces Blood-Brain Barrier Disruption and Local Macrophage/Microglia Activation
Authors: LRC de Oliveir, LAN Mimura, TFC Fraga-Silv, LLW Ishikawa, AAH Fernandes, SFG Zorzella-P, A Sartori
Front Pharmacol, 2020-03-12;11(0):161.
Species: Mouse
Sample Types: Cell Culture Supernates
-
HILPDA Uncouples Lipid Droplet Accumulation in Adipose Tissue Macrophages from Inflammation and Metabolic Dysregulation
Authors: XAMH van Dieren, MA de la Rosa, A Georgiadi, F Mattijssen, W Dijk, M van Weeghe, R Singh, JW Borst, R Stienstra, S Kersten
Cell Rep, 2020-02-11;30(6):1811-1822.e6.
Species: Mouse
Sample Types: Cell Cultue Supernates
-
Nose-Only Water-Pipe Smoke Exposure in Mice Elicits Renal Histopathological Alterations, Inflammation, Oxidative Stress, DNA Damage, and Apoptosis
Authors: A Nemmar, S Beegam, P Yuvaraju, J Yasin, BH Ali, E Adeghate
Front Physiol, 2020-02-11;11(0):46.
Species: Mouse
Sample Types: Tissue Homogenates
-
Fish oil reverses metabolic syndrome, adipocyte dysfunction, and altered adipokines secretion triggered by high-fat diet-induced obesity
Authors: RDC da Cunha d, MM Cruz, TM de Farias, VS da Silva, J de Jesus S, MM Telles, MIC Alonso-Val
Physiol Rep, 2020-02-01;8(4):e14380.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Distinct effects of general anesthetics on lung metastasis mediated by IL-6/JAK/STAT3 pathway in mouse models
Authors: R Li, Y Huang, J Lin
Nat Commun, 2020-01-31;11(1):642.
Species: Mouse
Sample Types: Serum
-
ACE2 activation protects against cognitive decline and reduces amyloid pathology in the Tg2576 mouse model of Alzheimer's disease.
Authors: Evans C, Miners J, Piva G, Willis C, Heard D, Kidd E, Good M, Kehoe P
Acta Neuropathol, 2020-01-25;139(3):485-502.
Species: Mouse
Sample Types: Tissue Homogenates
-
Rotavirus VP6 Adjuvant Effect on Norovirus GII.4 Virus-Like Particle Uptake and Presentation by Bone Marrow-Derived Dendritic Cells In Vitro and In Vivo
Authors: K Tamminen, S Heinimäki, T Vesikari, V Blazevic
J Immunol Res, 2020-01-23;2020(0):3194704.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Abnormal Cannabidiol Affects Production of Pro-Inflammatory Mediators and Astrocyte Wound Closure in Primary Astrocytic-Microglial Cocultures
Authors: J Cardinal v, T Hohmann, F Dehghani
Molecules, 2020-01-23;25(3):.
Species: Mouse
Sample Types: Cell Culture Supern
-
Periostin Promotes Colorectal Tumorigenesis through Integrin-FAK-Src Pathway-Mediated YAP/TAZ Activation
Authors: H Ma, J Wang, X Zhao, T Wu, Z Huang, D Chen, Y Liu, G Ouyang
Cell Rep, 2020-01-21;30(3):793-806.e6.
Species: Mouse
Sample Types: Tissue Homogenates
-
The Role of MKP-5 in Adipocyte-Macrophage Interactions during Obesity
Authors: Y Lu, J Ma, J Zhao, Z Song, C Zhou, X Liu, W Teng, W Wang, Q Zhang, W Yan, P Jiao
Obes Facts, 2020-01-21;0(0):1-16.
Species: Mouse
Sample Types: cell culture supernatant
-
Detrimental Role of Nerve Injury-Induced Protein 1 in Myeloid Cells under Intestinal Inflammatory Conditions
Authors: HJ Jung, JH Kang, S Pak, K Lee, JK Seong, SH Oh
Int J Mol Sci, 2020-01-17;21(2):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Allergic inflammation is initiated by IL-33-dependent crosstalk between mast cells and basophils
Authors: CL Hsu, KD Chhiba, R Krier-Burr, S Hosakoppal, S Berdnikovs, ML Miller, PJ Bryce
PLoS ONE, 2020-01-15;15(1):e0226701.
Species: Mouse
Sample Types: Cell Culture Superantes
-
Comparative Study on Pulmonary Toxicity in Mice Induced by Exposure to Unflavoured and Apple- and Strawberry-Flavoured Tobacco Waterpipe Smoke
Authors: A Nemmar, S Al-Salam, S Beegam, P Yuvaraju, BH Ali
Oxid Med Cell Longev, 2020-01-14;2020(0):6450450.
Species: Mouse
Sample Types: Tissue Homogenates
-
I&kappaB? controls NLRP3 inflammasome activation via upregulation of the Nlrp3 gene
Authors: J Kim, H Ahn, S Yu, JH Ahn, HJ Ko, MN Kweon, EJ Hong, BS An, E Lee, GS Lee
Cytokine, 2020-01-07;127(0):154983.
Species: Mouse
Sample Types: Serum
-
The role of uncoupling protein 2 in macrophages and its impact on obesity-induced adipose tissue inflammation and insulin resistance
Authors: XAMH van Dieren, T Sancerni, MC Alves-Guer, R Stienstra
J Biol Chem, 2020-01-01;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
The alternative cap-binding complex is required for antiviral defense in vivo
Authors: A Gebhardt, V Bergant, D Schnepf, M Moser, A Meiler, D Togbe, C Mackowiak, LS Reinert, SR Paludan, B Ryffel, A Stukalov, P Staeheli, A Pichlmair
PLoS Pathog., 2019-12-19;15(12):e1008155.
Species: Mouse
Sample Types: Cell culture supernat
-
Flagellin-elicited adaptive immunity suppresses flagellated microbiota and vaccinates against chronic inflammatory diseases
Authors: HQ Tran, RE Ley, AT Gewirtz, B Chassaing
Nat Commun, 2019-12-11;10(1):5650.
Species: Mouse
Sample Types: Serum
-
Mucoadhesive dexamethasone-glycol chitosan nanoparticles for ophthalmic drug delivery
Authors: A Yu, H Shi, H Liu, Z Bao, M Dai, D Lin, D Lin, X Xu, X Li, Y Wang
Int J Pharm, 2019-12-09;575(0):118943.
Species: Mouse
Sample Types: Cell Culture Supernates
-
PASylation of IL-1 Receptor antagonist (IL-1Ra) retains IL-1 blockade and extends its duration in mouse urate crystal-induced peritonitis
Authors: NE Powers, B Swartzwelt, C Marchetti, DM de Graaf, A Lerchner, M Schlapschy, R Datar, U Binder, CK Edwards, A Skerra, CA Dinarello
J. Biol. Chem., 2019-12-09;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
SOCS2 modulates adipose tissue inflammation and expansion in mice
Authors: CH Val, MC de Oliveir, DR Lacerda, A Barroso, NV Batista, Z Menezes-Ga, DRR de Assis, AT Cramer, F Brant, MM Teixeira, D Glória Sou, AM Ferreira, FS Machado
J. Nutr. Biochem., 2019-11-23;76(0):108304.
Species: Mouse
Sample Types: Tissue Homogenates
-
Adiponectin Reverses the Hypothalamic Microglial Inflammation during Short-Term Exposure to Fat-Rich Diet
Authors: H Lee, TH Tu, BS Park, S Yang, JG Kim
Int J Mol Sci, 2019-11-15;20(22):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
A novel mouse model for septic arthritis induced by Pseudomonas aeruginosa
Authors: T Jin, M Mohammad, Z Hu, Y Fei, ERB Moore, R Pullerits, A Ali
Sci Rep, 2019-11-14;9(1):16868.
Species: Mouse
Sample Types: Serum
-
Roxatidine inhibits fibrosis by inhibiting NF?kappaB and MAPK signaling in macrophages sensing breast implant surface materials
Authors: L Ji, T Wang, L Tian, H Song, M Gao
Mol Med Rep, 2019-11-12;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
The effects of oxygen concentration on cell death, anti-oxidant transcription, acute inflammation, and cell proliferation in precision-cut lung slices
Authors: MJR Ruigrok, J Tomar, HW Frijlink, BN Melgert, WLJ Hinrichs, P Olinga
Sci Rep, 2019-11-07;9(1):16239.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Rupintrivir reduces RV-induced TH-2 cytokine IL-4 in precision-cut lung slices (PCLS) of HDM-sensitized mice ex vivo
Authors: O Danov, L Lasswitz, H Obernolte, C Hesse, A Braun, S Wronski, K Sewald
Respir. Res., 2019-10-22;20(1):228.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Endoplasmic reticulum stress differentially modulates the IL-6 family of cytokines in murine astrocytes and macrophages
Authors: CL Sanchez, SG Sims, JD Nowery, GP Meares
Sci Rep, 2019-10-17;9(1):14931.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Enzyme Treatment Alters the Anti-Inflammatory Activity of the Water Extract of Wheat Germ In Vitro and In Vivo
Authors: Y Song, HY Jeong, JK Lee, YS Choi, DO Kim, D Jang, CS Park, S Maeng, H Kang
Nutrients, 2019-10-16;11(10):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Inhibition of ErbB kinase signalling promotes resolution of neutrophilic inflammation
Authors: A Rahman, KM Henry, KD Herman, AAR Thompson, HM Isles, C Tulotta, D Sammut, JJ Rougeot, N Khoshaein, AE Reese, K Higgins, C Tabor, I Sabroe, WJ Zuercher, CO Savage, AH Meijer, MK Whyte, DH Dockrell, SA Renshaw, LR Prince
Elife, 2019-10-15;8(0):.
Species: Mouse
Sample Types: Peritoneal Lavage Fluid
-
Targeting TGFbetaR2-mutant tumors exposes vulnerabilities to stromal TGFbeta blockade in pancreatic cancer
Authors: H Huang, Y Zhang, V Gallegos, N Sorrelle, MM Zaid, J Toombs, W Du, S Wright, M Hagopian, Z Wang, AN Hosein, AA Sathe, C Xing, EJ Koay, KE Driscoll, RA Brekken
EMBO Mol Med, 2019-10-14;0(0):e10515.
Species: Mouse
Sample Types: Tissue Lysates
-
Relative Contributions of Extracellular and Internalized Bacteria to Early Macrophage Proinflammatory Responses to Streptococcus pneumoniae
Authors: J Periselner, G Ercoli, T Pollard, S Chimalapat, E Camberlein, G Szylar, C Hyams, G Tomlinson, FC Petersen, RA Floto, M Noursadegh, JS Brown
MBio, 2019-09-24;10(5):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Non-hematopoietic STAT6 induces epithelial tight junction dysfunction and promotes intestinal inflammation and tumorigenesis
Authors: Y Lin, B Li, X Yang, T Liu, T Shi, B Deng, Y Zhang, L Jia, Z Jiang, R He
Mucosal Immunol, 2019-09-18;0(0):.
Species: Mouse
Sample Types: Tissue Homogenates
-
PTP1B negatively regulates nitric oxide-mediated Pseudomonas aeruginosa killing by neutrophils
Authors: L Yue, M Yan, ML Tremblay, TJ Lin, H Li, T Yang, X Song, T Xie, Z Xie
PLoS ONE, 2019-09-18;14(9):e0222753.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Comprehensive characterization of silica-modified silicon rubbers
Authors: I Chiulan, DM Panaitescu, ER Radu, AN Frone, RA Gabor, CA Nicolae, G Jinescu, V Tofan, G Chinga-Car
J Mech Behav Biomed Mater, 2019-09-10;101(0):103427.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Melatonin Supplementation Attenuates the Pro-Inflammatory Adipokines Expression in Visceral Fat from Obese Mice Induced by A High-Fat Diet
Authors: TDSM Farias, RID Paixao, MM Cruz, RDCDC de Sa, JJ Simão, VJ Antraco, MIC Alonso-Val
Cells, 2019-09-06;8(9):.
Species: Mouse
Sample Types: Tissue Lysates
-
Evidence of CD40L/CD40 pathway involvement in experimental transfusion-related acute lung injury
Authors: S Tariket, H Hamzeh-Cog, S Laradi, CA Arthaud, MA Eyraud, T Bourlet, P Berthelot, O Garraud, F Cognasse
Sci Rep, 2019-08-29;9(1):12536.
Species: Mouse
Sample Types: Plasma
-
Pseudomonas aeruginosa Lipoxygenase LoxA Contributes to Lung Infection by Altering the Host Immune Lipid Signaling
Authors: E Morello, T Pérez-Bere, C Boisseau, T Baranek, A Guillon, D Bréa, P Lanotte, X Carpena, N Pietrancos, V Hervé, R Ramphal, N Cenac, M Si-Tahar
Front Microbiol, 2019-08-14;10(0):1826.
Species: Mouse
Sample Types: BALF
-
Nitric Oxide Modulates Metabolic Remodeling in Inflammatory Macrophages through TCA Cycle Regulation and Itaconate Accumulation
Authors: JD Bailey, M Diotallevi, T Nicol, E McNeill, A Shaw, S Chuaiphich, A Hale, A Starr, M Nandi, E Stylianou, H McShane, S Davis, R Fischer, BM Kessler, J McCullagh, KM Channon, MJ Crabtree
Cell Rep, 2019-07-02;28(1):218-230.e7.
Species: Mouse, Transgenic Mouse
Sample Types: Cell Culture Supernates
-
Ablation of RhoA impairs Th17 cell differentiation and alleviates house dust mite-triggered allergic airway inflammation
Authors: JQ Yang, KW Kalim, Y Li, Y Zheng, F Guo
J. Leukoc. Biol., 2019-07-01;0(0):.
Species: Mouse
Sample Types: BALF
-
Glucose Ingestion Inhibits Endurance Exercise-Induced IL-6 Producing Macrophage Infiltration in Mice Muscle
Authors: T Tominaga, S Ma, K Saitou, K Suzuki
Nutrients, 2019-06-30;11(7):.
Species: Mouse
Sample Types: Plasma
-
Oral administration of EPA-rich oil impairs collagen reorganization due to elevated production of IL-10 during skin wound healing in mice
Authors: B Burger, CMC Kühl, T Candreva, RDS Cardoso, JR Silva, BG Castelucci, SR Consonni, HL Fisk, PC Calder, MAR Vinolo, HG Rodrigues
Sci Rep, 2019-06-24;9(1):9119.
Species: Mouse
Sample Types: Tissue Homogenates
-
The YIN and YANG of lipoproteins in developing and preventing infectious arthritis by Staphylococcus aureus
Authors: M Mohammad, MT Nguyen, C Engdahl, M Na, A Jarneborn, Z Hu, A Karlsson, R Pullerits, A Ali, F Götz, T Jin
PLoS Pathog., 2019-06-21;15(6):e1007877.
Species: Mouse
Sample Types: Tissue Homogenates
-
Role of adipose tissue inflammation in fat pad loss induced by fasting in lean and mildly obese mice
Authors: DR Lacerda, KA Costa, ALM Silveira, DF Rodrigues, AN Silva, JL Sabino, V Pinho, GB Menezes, DD Soares, MM Teixeira, AVM Ferreira
J. Nutr. Biochem., 2019-06-21;72(0):108208.
Species: Mouse
Sample Types: Tissue Homogenates
-
IL-33 drives group 2 innate lymphoid cell-mediated protection during Clostridium difficile infection
Authors: AL Frisbee, MM Saleh, MK Young, JL Leslie, ME Simpson, MM Abhyankar, CA Cowardin, JZ Ma, P Pramoonjag, SD Turner, AP Liou, EL Buonomo, WA Petri
Nat Commun, 2019-06-20;10(1):2712.
Species: Mouse
Sample Types: Tissue Homogenates
-
In-depth characterization of congenital Zika syndrome in immunocompetent mice: Antibody-dependent enhancement and an antiviral peptide therapy
Authors: VN Camargos, G Foureaux, DC Medeiros, VT da Silveir, CM Queiroz-Ju, ALB Matosinhos, AFA Figueiredo, CDF Sousa, TP Moreira, VF Queiroz, ACF Dias, KTO Santana, I Passos, ALCV Real, LC Silva, FAG Mourão, NT Wnuk, MAP Oliveira, S Macari, T Silva, GP Garlet, JA Jackman, FM Soriani, MFD Moraes, EMAM Mendes, FM Ribeiro, GMJ Costa, AL Teixeira, NJ Cho, ACP Oliveira, MM Teixeira, VV Costa, DG Souza
EBioMedicine, 2019-05-23;0(0):.
Species: Mouse
Sample Types: Plasma
-
The immunoreceptor CD300a controls the intensity of inflammation and dysfunction in a model of Ag-induced arthritis in mice
Authors: BVS Valiate, RU Alvarez, L Karra, CM Queiroz-Jú, FA Amaral, F Levi-Schaf, MM Teixeira
J. Leukoc. Biol., 2019-05-20;0(0):.
Species: Mouse
Sample Types: Tissue Homogenates
-
Innate immune memory through TLR2 and NOD2 contributes to the control of Leptospira interrogans infection
Authors: I Santecchia, F Vernel-Pau, O Rasid, J Quintin, M Gomes-Sole, IG Boneca, C Werts
PLoS Pathog., 2019-05-20;15(5):e1007811.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Conjugated bile acids attenuate allergen-induced airway inflammation and hyperresposiveness by inhibiting UPR transducers
Authors: EM Nakada, NR Bhakta, BR Korwin-Mih, A Kumar, N Chamberlai, SR Bruno, DG Chapman, SM Hoffman, N Daphtary, M Aliyeva, CG Irvin, AE Dixon, PG Woodruff, S Amin, ME Poynter, DH Desai, V Anathy
JCI Insight, 2019-05-02;4(9):.
Species: Mouse
Sample Types: Tissue Homogenates
-
A Live Salmonella Vaccine Delivering PcrV through the Type III Secretion System Protects against Pseudomonas aeruginosa
Authors: J Aguilera-H, M García-Qui, R Romero-Flo, MJ McConnell, F Ramos-Mora
mSphere, 2019-04-17;4(2):.
Species: Mouse
Sample Types: Serum
-
Butyrate Protects Mice from Clostridium difficile-Induced Colitis through an HIF-1-Dependent Mechanism
Authors: JL Fachi, JS Felipe, LP Pral, BK da Silva, RO Corrêa, MCP de Andrade, DM da Fonseca, PJ Basso, NOS Câmara, ÉL de Sales E, F Dos Santos, SES Guima, AM Thomas, JC Setubal, YT Magalhães, FL Forti, T Candreva, HG Rodrigues, MB de Jesus, SR Consonni, ADS Farias, P Varga-Weis, MAR Vinolo
Cell Rep, 2019-04-16;27(3):750-761.e7.
Species: Mouse
Sample Types: Tissue Homogenates
-
Human metapneumovirus activates NOD-like receptor protein 3 inflammasome via its small hydrophobic protein which plays a detrimental role during infection in mice
Authors: VB Lê, J Dubois, C Couture, MH Cavanagh, O Uyar, A Pizzorno, M Rosa-Calat, MÈ Hamelin, G Boivin
PLoS Pathog., 2019-04-09;15(4):e1007689.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Effects of IGF-1 isoforms on muscle growth and sarcopenia
Authors: F Ascenzi, L Barberi, G Dobrowolny, A Villa Nova, C Nicoletti, E Rizzuto, N Rosenthal, BM Scicchitan, A Musarò
Aging Cell, 2019-04-05;0(0):e12954.
Species: Mouse
Sample Types: Serum
-
PtdIns3P phosphatases MTMR3 and MTMR4 negatively regulate innate immune responses to DNA through modulating STING trafficking
Authors: DDP Putri, T Kawasaki, M Murase, T Sueyoshi, T Deguchi, D Ori, S Suetsugu, T Kawai
J. Biol. Chem., 2019-04-03;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
The three cytokines IL-1?, IL-18, and IL-1? share related but distinct secretory routes
Authors: VS Tapia, MJD Daniels, P Palazón-Ri, M Dewhurst, NM Luheshi, J Rivers-Aut, J Green, E Redondo-Ca, P Kaldis, G Lopez-Cast, D Brough
J. Biol. Chem., 2019-04-02;294(21):8325-8335.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Immunomodulatory effects of cyanobacterial toxin cylindrospermopsin on innate immune cells
Authors: Z Moosova, M Pekarova, LS Sindlerova, O Vasicek, L Kubala, L Blaha, O Adamovsky
Chemosphere, 2019-03-29;226(0):439-446.
Species: Mouse
Sample Types: Cell Culture Supernates
-
NLRX1 does not play a role in diabetes nor the development of diabetic nephropathy induced by multiple low doses of streptozotocin
Authors: AML Scantleber, M Uil, LM Butter, R Poelman, N Claessen, SE Girardin, S Florquin, JJTH Roelofs, JC Leemans
PLoS ONE, 2019-03-25;14(3):e0214437.
Species: Mouse
Sample Types: Tissue Homogenates
-
Exosomes derived from umbilical cord mesenchymal stem cells reduce microglia-mediated neuroinflammation in perinatal brain injury
Authors: G Thomi, D Surbek, V Haesler, M Joerger-Me, A Schoeberle
Stem Cell Res Ther, 2019-03-21;10(1):105.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Exercise-induced AMPK activation and IL-6 muscle production are disturbed in adiponectin knockout mice
Authors: TA Diniz, JCJ Aquino Jún, FC Mosele, C Cabral-San, EA Lima Junio, AAS Teixeira, FS Lira, JC Rosa Neto
Cytokine, 2019-03-20;119(0):71-80.
Species: Mouse
Sample Types: Tissue Homogenates
-
Urolithin A attenuates memory impairment and neuroinflammation in APP/PS1 mice
Authors: Z Gong, J Huang, B Xu, Z Ou, L Zhang, X Lin, X Ye, X Kong, D Long, X Sun, X He, L Xu, Q Li, A Xuan
J Neuroinflammation, 2019-03-14;16(1):62.
Species: Mouse
Sample Types: Tissue Homogenates
-
Effect of antibiotic infused calcium sulfate/hydroxyapatite (CAS/HA) insets on implant-associated osteitis in a femur fracture model in mice
Authors: L Oezel, C Büren, AO Scholz, J Windolf, CD Windolf
PLoS ONE, 2019-03-14;14(3):e0213590.
Species: Mouse
Sample Types: Wound Lavage Fluid
-
The NLRP3 inflammasome modulates glycolysis by increasing PFKFB3 in an IL-1?-dependent manner in macrophages
Authors: OM Finucane, J Sugrue, A Rubio-Arai, MV Guillot-Se, MA Lynch
Sci Rep, 2019-03-11;9(1):4034.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Interleukin-37 monomer is the active form for reducing innate immunity
Authors: EZ Eisenmesse, A Gottschlic, JS Redzic, N Paukovich, JC Nix, T Azam, L Zhang, R Zhao, JS Kieft, E The, X Meng, CA Dinarello
Proc. Natl. Acad. Sci. U.S.A., 2019-02-28;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Anti-leishmanial activity of Brevinin 2R and its Lauric acid conjugate type against L. major: In vitro mechanism of actions and in vivo treatment potentials
Authors: F Zahedifard, H Lee, JH No, M Salimi, N Seyed, A Asoodeh, S Rafati
PLoS Negl Trop Dis, 2019-02-27;13(2):e0007217.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Long noncoding RNA Malat1 regulates differential activation of macrophage and response to lung injury
Authors: H Cui, S Banerjee, S Guo, N Xie, J Ge, D Jiang, M Zörnig, VJ Thannickal, G Liu
JCI Insight, 2019-02-21;0(0):.
Species: Mouse
Sample Types: Serum
-
Macrophage-dependent neutrophil recruitment is impaired under conditions of increased intestinal permeability in JAM-A-deficient mice
Authors: AC Luissint, HC Williams, W Kim, S Flemming, V Azcutia, RS Hilgarth, MNO Leary, TL Denning, A Nusrat, CA Parkos
Mucosal Immunol, 2019-02-11;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Innate Sensing through Mesenchymal TLR4/MyD88 Signals Promotes Spontaneous Intestinal Tumorigenesis
Authors: V Koliaraki, N Chalkidi, A Henriques, C Tzaferis, A Polykratis, A Waisman, W Muller, DJ Hackam, M Pasparakis, G Kollias
Cell Rep, 2019-01-15;26(3):536-545.e4.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Modifying internal organization and surface morphology of siRNA lipoplexes by sodium alginate addition for efficient siRNA delivery
Authors: DC Arruda, IJ Gonzalez, S Finet, L Cordova, V Trichet, GF Andrade, C Hoffmann, P Bigey, WA de Almeida, A Da Silva C, A Malachias, V Escriou
J Colloid Interface Sci, 2019-01-14;540(0):342-353.
Species: Mouse
Sample Types: Serum
-
The circadian regulator Bmal1 in joint mesenchymal cells regulates both joint development and inflammatory arthritis
Authors: LE Hand, SH Dickson, AJ Freemont, DW Ray, JE Gibbs
Arthritis Res. Ther., 2019-01-06;21(1):5.
Species: Mouse
Sample Types: Serum
-
Effect of Saururus chinensis leaves extract on type II collagen-induced arthritis mouse model
Authors: JH Nho, HJ Lee, HK Jung, JH Jang, KH Lee, AH Kim, TK Sung, HW Cho
BMC Complement Altern Med, 2019-01-03;19(1):2.
Species: Mouse
Sample Types: Serum
-
Water Extract of Acori Graminei Rhizoma Attenuates Features of Rheumatoid Arthritis in DBA/1 Mice
Authors: JH Nho, AH Kim, HK Jung, MJ Lee, JH Jang, BD Yang, HJ Lee, KH Lee, KW Woo, HW Cho
Evid Based Complement Alternat Med, 2019-01-01;2019(0):3637453.
Species: Mouse
Sample Types: Serum
-
In�Vitro Macrophage Assay Predicts the In�Vivo Anti-inflammatory Potential of Exosomes from Human Mesenchymal Stromal Cells
Authors: N Pacienza, RH Lee, EH Bae, DK Kim, Q Liu, DJ Prockop, G Yannarelli
Mol Ther Methods Clin Dev, 2018-12-15;13(0):67-76.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Eugenol as a Promising Molecule for the Treatment of Dermatitis: Antioxidant and Anti-inflammatory Activities and Its Nanoformulation
Authors: A de Araújo, FN da Fonseca, TM Rocha, LB de Freitas, EVO Araújo, DVT Wong, RCP Lima Júnio, LKAM Leal
Oxid Med Cell Longev, 2018-12-11;2018(0):8194849.
Species: Mouse
Sample Types: Tissue Homogenates
-
Intermittent Hypoxia Activates Duration-Dependent Protective and Injurious Mechanisms in Mouse Lung Endothelial Cells
Authors: P Wohlrab, L Soto-Gonza, T Benesch, MP Winter, IM Lang, K Markstalle, V Tretter, KU Klein
Front Physiol, 2018-12-06;9(0):1754.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Inflammation in the hippocampus affects IGF1 receptor signaling and contributes to neurological sequelae in rheumatoid arthritis
Authors: KME Andersson, C Wasén, L Juzokaite, L Leifsdotti, MC Erlandsson, ST Silfverswä, A Stokowska, M Pekna, M Pekny, K Olmarker, RA Heckemann, M Kalm, MI Bokarewa
Proc. Natl. Acad. Sci. U.S.A., 2018-12-03;0(0):.
Species: Mouse
Sample Types: Serum
-
Genetically Engineered Resveratrol-Enriched Rice Inhibits Neuroinflammation in Lipopolysaccharide-Activated BV2 Microglia Via Downregulating Mitogen-Activated Protein Kinase-Nuclear Factor Kappa B Signaling Pathway
Authors: L Subedi, SH Baek, SY Kim
Oxid Med Cell Longev, 2018-12-03;2018(0):8092713.
Species: Mouse
Sample Types: Cell Culture Supernates
-
DNA-PK Is Targeted by Multiple Vaccinia Virus Proteins to Inhibit DNA Sensing
Authors: SR Scutts, SW Ember, H Ren, C Ye, CA Lovejoy, M Mazzon, DL Veyer, RP Sumner, GL Smith
Cell Rep, 2018-11-13;25(7):1953-1965.e4.
Species: Mouse
Sample Types: Cell Culture Supernates
-
A non-canonical autophagy-dependent role of the ATG16L1T300A variant in urothelial vesicular trafficking and uropathogenic Escherichia coli persistence
Authors: C Wang, KA Bauckman, ASB Ross, JW Symington, MM Ligon, G Scholtes, A Kumar, HW Chang, J Twentyman, BE Fashemi, RJ Xavier, IU Mysorekar
Autophagy, 2018-11-08;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
EGF receptor plays a role in the mechanism of glutamine-mediated prevention of alcohol-induced gut barrier dysfunction and liver injury
Authors: AS Meena, PK Shukla, P Sheth, R Rao
J. Nutr. Biochem., 2018-11-06;64(0):128-143.
Species: Mouse
Sample Types: Plasma
-
Bovine milk-derived extracellular vesicles enhance inflammation and promote M1 polarization following agricultural dust exposure in mice
Authors: TM Nordgren, AJ Heires, J Zempleni, BJ Swanson, C Wichman, DJ Romberger
J. Nutr. Biochem., 2018-11-03;64(0):110-120.
Species: Mouse
Sample Types: BALF
-
Human Defensin-5 Blocks Ethanol and Colitis-Induced Dysbiosis, Tight Junction Disruption and Inflammation in Mouse Intestine
Authors: PK Shukla, AS Meena, V Rao, RG Rao, L Balazs, R Rao
Sci Rep, 2018-11-02;8(1):16241.
Species: Mouse
Sample Types: Plasma
-
Preconditioning of bone marrow-derived mesenchymal stem cells highly strengthens their potential to promote IL-6-dependent M2b polarization
Authors: D Philipp, L Suhr, T Wahlers, YH Choi, A Paunel-Gör
Stem Cell Res Ther, 2018-10-25;9(1):286.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Myocardial Ischemia Reperfusion Injury: Apoptotic, Inflammatory and Oxidative Stress Role of Galectin-3
Authors: S Al-Salam, S Hashmi
Cell. Physiol. Biochem., 2018-10-24;50(3):1123-1139.
Species: Mouse
Sample Types: Tissue Homogenates
-
LncRNA HOTAIR regulates lipopolysaccharide-induced cytokine expression and inflammatory response in macrophages
Authors: M Obaid, SMN Udden, P Deb, N Shihabeddi, MH Zaki, SS Mandal
Sci Rep, 2018-10-23;8(1):15670.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Discovery of a Novel Microtubule Targeting Agent as an Adjuvant for Cancer Immunotherapy
Authors: F Sato-Kanek, X Wang, S Yao, T Hosoya, FS Lao, K Messer, M Pu, NM Shukla, HB Cottam, M Chan, DA Carson, M Corr, T Hayashi
Biomed Res Int, 2018-10-10;2018(0):8091283.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Harmful Roles of TLR3 and TLR9 in Cardiac Dysfunction Developing during Polymicrobial Sepsis
Authors: F Fattahi, MW Russell, EA Malan, M Parlett, E Abe, FS Zetoune, PA Ward
Biomed Res Int, 2018-09-30;2018(0):4302726.
Species: Mouse
Sample Types: Plasma
-
Insufficient IL-10 Production as a Mechanism Underlying the Pathogenesis of Systemic Juvenile Idiopathic Arthritis
Authors: M Imbrechts, A Avau, J Vandenhaut, B Malengier-, K Put, T Mitera, N Berghmans, O Burton, S Junius, A Liston, L de Somer, C Wouters, P Matthys
J. Immunol., 2018-09-28;0(0):.
Species: Mouse
Sample Types: Plasma
-
Fibrosis-associated hepatocarcinogenesis revisited: Establishing standard medium-term chemically-induced male and female models
Authors: GR Romualdo, GB Prata, TC da Silva, AAH Fernandes, FS Moreno, B Cogliati, LF Barbisan
PLoS ONE, 2018-09-13;13(9):e0203879.
Species: Mouse
Sample Types: Tissue Homogenates
-
GWAS for Interleukin-1? levels in gingival crevicular fluid identifies IL37 variants in periodontal inflammation
Authors: S Offenbache, Y Jiao, SJ Kim, J Marchesan, KL Moss, L Jing, K Divaris, S Bencharit, CS Agler, T Morelli, S Zhang, L Sun, WT Seaman, D Cowley, SP Barros, JD Beck, M Munz, AS Schaefer, KE North
Nat Commun, 2018-09-11;9(1):3686.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Interferon-gamma inhibits seminal plasma induction of colony stimulating factor 2 in mouse and human reproductive tract epithelial cells
Authors: DJ Sharkey, DJ Glynn, JE Schjenken, KP Tremellen, SA Robertson
Biol. Reprod., 2018-09-01;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
The histamine H3R antagonist DL77 attenuates autistic behaviors in a prenatal valproic acid-induced mouse model of autism
Authors: N Eissa, P Jayaprakas, S Azimullah, SK Ojha, M Al-Houqani, FY Jalal, D ?a?ewska, K Kie?-Konon, B Sadek
Sci Rep, 2018-08-30;8(1):13077.
Species: Mouse
Sample Types: Tissue Homogenates
-
Myeloperoxidase deficiency attenuates systemic and dietary iron-induced adverse effects
Authors: X Xiao, P Saha, BS Yeoh, JA Hipp, V Singh, M Vijay-Kuma
J. Nutr. Biochem., 2018-08-21;62(0):28-34.
Species: Mouse
Sample Types: Tissue Homogenates
-
Helminths-based bi-functional molecule, tuftsin-phosphorylcholine (TPC), ameliorates an established murine arthritis
Authors: M Blank, T Bashi, J Lachnish, D Ben-Ami-Sh, O Shovman, M Fridkin, M Eisenstein, A Volkov, I Barshack, Y Shoenfeld
PLoS ONE, 2018-08-08;13(8):e0200615.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Extracellular ATP is a danger signal activating P2X7 receptor in a LPS mediated inflammation (ARDS/ALI)
Authors: S Cicko, TC Köhler, CK Ayata, T Müller, N Ehrat, A Meyer, M Hossfeld, A Zech, F Di Virgili, M Idzko
Oncotarget, 2018-07-17;9(55):30635-30648.
Species: Mouse
Sample Types: BALF
-
Apigenin Retards Atherogenesis by Promoting ABCA1-Mediated Cholesterol Efflux and Suppressing Inflammation
Authors: K Ren, T Jiang, HF Zhou, Y Liang, GJ Zhao
Cell. Physiol. Biochem., 2018-07-05;47(5):2170-2184.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Integration of T Cell Receptor, Notch and Cytokine Signals Programs in Mouse ?? T Cell Effector Differentiation
Authors: P Zarin, TSH In, ELY Chen, J Singh, GW Wong, M Mohtashami, DL Wiest, MK Anderson, JC Zúñiga-Pfl
Immunol. Cell Biol., 2018-06-28;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Induction of endoplasmic reticulum stress under endotoxin tolerance increases inflammatory responses and decreases Pseudomonas aeruginosa pneumonia
Authors: S Kim, Y Joe, SU Park, SO Jeong, JK Kim, SH Park, HO Pae, YJ Surh, J Shin, HT Chung
J. Leukoc. Biol., 2018-06-20;0(0):.
Species: Mouse
Sample Types: BALF
-
Choline transport links macrophage phospholipid metabolism and inflammation
Authors: SA Snider, KD Margison, P Ghorbani, ND LeBlond, C O'Dwyer, JR Nunes, T Nguyen, H Xu, SA Bennett, MD Fullerton
J. Biol. Chem., 2018-06-07;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Anti-inflammatory properties of ursodeoxycholyl lysophosphatidylethanolamide in endotoxin-mediated inflammatory liver injury
Authors: JM Ludwig, Y Zhang, W Chamulitra, W Stremmel, A Pathil
PLoS ONE, 2018-05-24;13(5):e0197836.
Species: Mouse
Sample Types: Cell Culture Supernates
-
CD71+ Erythroid Suppressor Cells Promote Fetomaternal Tolerance through Arginase-2 and PDL-1
Authors: C Delyea, N Bozorgmehr, P Koleva, G Dunsmore, S Shahbaz, V Huang, S Elahi
J. Immunol., 2018-05-07;0(0):.
Species: Mouse
Sample Types: Tissue Homogenates
-
Lysosomal Protein Lamtor1 Controls Innate Immune Responses via Nuclear Translocation of Transcription Factor EB
Authors: Y Hayama, T Kimura, Y Takeda, S Nada, S Koyama, H Takamatsu, S Kang, D Ito, Y Maeda, M Nishide, S Nojima, H Sarashina-, T Hosokawa, Y Kinehara, Y Kato, T Nakatani, Y Nakanishi, T Tsuda, T Koba, M Okada, A Kumanogoh
J. Immunol., 2018-04-23;0(0):.
Species: Mouse
Sample Types: BALF
-
Electrophilic properties of itaconate and derivatives regulate the�I?B?-ATF3 inflammatory axis
Authors: M Bambouskov, L Gorvel, V Lampropoul, A Sergushich, E Loginichev, K Johnson, D Korenfeld, ME Mathyer, H Kim, LH Huang, D Duncan, H Bregman, A Keskin, A Santeford, RS Apte, R Sehgal, B Johnson, GK Amarasingh, MP Soares, T Satoh, S Akira, T Hai, C de Guzman, K Auclair, TP Roddy, SA Biller, M Jovanovic, E Klechevsky, KM Stewart, GJ Randolph, MN Artyomov
Nature, 2018-04-18;556(7702):501-504.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Parkin deficiency modulates NLRP3 inflammasome activation by attenuating an A20-dependent negative feedback loop
Authors: F Mouton-Lig, T Rosazza, J Sepulveda-, A Ieang, SM Hassoun, E Claire, G Mangone, A Brice, PP Michel, JC Corvol, O Corti
Glia, 2018-04-17;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Alternaria alternata challenge at the nasal mucosa results in eosinophilic inflammation and increased susceptibility to influenza virus infection
Authors: M Ma, JL Redes, CM Percopo, KM Druey, HF Rosenberg
Clin. Exp. Allergy, 2018-04-15;0(0):.
Species: Mouse
Sample Types: Nasal Lavage Fluid
-
Genetic ablation of histone deacetylase 2 leads to lung cellular senescence and lymphoid follicle formation in COPD/emphysema
Authors: IK Sundar, K Rashid, J Gerloff, J Rangel-Mor, D Li, I Rahman
FASEB J., 2018-04-09;0(0):fj201701518R.
Species: Mouse
Sample Types: Tissue Homogenates
-
p53 in Bronchial Club Cells Facilitates Chronic Lung Inflammation by Promoting Senescence
Authors: A Sagiv, A Bar-Shai, N Levi, M Hatzav, L Zada, Y Ovadya, L Roitman, G Manella, O Regev, J Majewska, E Vadai, R Eilam, SW Feigelson, M Tsoory, M Tauc, R Alon, V Krizhanovs
Cell Rep, 2018-03-27;22(13):3468-3479.
Species: Mouse
Sample Types: BALF
-
Intravesicular Acidification Regulates Lipopolysaccharide Inflammation and Tolerance through TLR4 Trafficking
Authors: M Murase, T Kawasaki, R Hakozaki, T Sueyoshi, DDP Putri, Y Kitai, S Sato, M Ikawa, T Kawai
J. Immunol., 2018-03-14;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
The Long Pentraxin 3 Plays a Role in Bone Turnover and Repair
Authors: D Gr?evi?, M Sironi, S Valentino, L Deban, H Cvija, A Inforzato, N Kova?i?, V Katavi?, T Kelava, I Kalajzi?, A Mantovani, B Bottazzi
Front Immunol, 2018-03-05;9(0):417.
Species: Mouse
Sample Types: Serum
-
Capturing the multifactorial nature of ARDS - "Two-hit" approach to model murine acute lung injury
Authors: S Hoegl, N Burns, M Angulo, D Francis, CM Osborne, TW Mills, MR Blackburn, HK Eltzschig, CU Vohwinkel
Physiol Rep, 2018-03-01;6(6):e13648.
Species: Mouse
Sample Types: BALF
-
Activation of macrophage mediated host defense againstSalmonella typhimuriumbyMorus albaL
Authors: B Chang, B Koo, H Lee, JS Oh, S Kim
Food Nutr Res, 2018-02-21;62(0):.
Species: Mouse
Sample Types: Serum
-
An unexpected link between fatty acid synthase and cholesterol synthesis in proinflammatory macrophage activation
Authors: RG Carroll, Z Zas?ona, S Galván-Peñ, EL Koppe, DC Sévin, S Angiari, M Triantafil, K Triantafil, LK Modis, LA O'Neill
J. Biol. Chem., 2018-02-20;293(15):5509-5521.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Immunomodulatory effects of polysaccharide fraction isolated from Fagopyrum esculentum on innate immune system
Authors: MJ Oh, HD Choi, SK Ha, I Choi, HY Park
Biochem. Biophys. Res. Commun., 2018-01-31;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
EBI2 regulates pro-inflammatory signalling and cytokine release in astrocytes
Authors: A Rutkowska, DR Shimshek, AW Sailer, KK Dev
Neuropharmacology, 2018-01-31;133(0):121-128.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Age-related cognitive impairment is associated with long-term neuroinflammation and oxidative stress in a mouse model of episodic systemic inflammation
Authors: JC d'Avila, LD Siqueira, A Mazeraud, EP Azevedo, D Foguel, HC Castro-Far, T Sharshar, F Chrétien, FA Bozza
J Neuroinflammation, 2018-01-30;15(1):28.
Species: Mouse
Sample Types: Tissue Homogenates
-
Stimulation of TNF receptor type 2 expands regulatory T cells and ameliorates established collagen-induced arthritis in mice
Authors: V Lamontain, T Schmid, D Weber-Stef, D Zeller, Z Jenei-Lanz, H Wajant, RH Straub, DN Männel
Cell. Mol. Immunol., 2018-01-29;0(0):.
Species: Mouse
Sample Types: Serum
-
Complement C5a Receptor 1 Exacerbates the Pathophysiology of N.�meningitidis Sepsis and Is a Potential Target for Disease Treatment
Authors: JB Herrmann, M Muensterma, L Strobel, A Schubert-U, TM Woodruff, SD Gray-Owen, A Klos, KO Johswich
MBio, 2018-01-23;9(1):.
Species: Mouse
Sample Types: Whole Blood
-
Unique metabolic activation of adipose tissue macrophages in obesity promotes inflammatory responses
Authors: L Boutens, GJ Hooiveld, S Dhingra, RA Cramer, MG Netea, R Stienstra
Diabetologia, 2018-01-14;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Necroptosis promotes autophagy-dependent upregulation of DAMP and results in immunosurveillance
Authors: SY Lin, SY Hsieh, YT Fan, WC Wei, PW Hsiao, DH Tsai, TS Wu, NS Yang
Autophagy, 2017-12-31;0(0):0.
Species: Mouse
Sample Types: Cell Culture Supernates
-
The Absence of NOD1 Enhances Killing of Aspergillus fumigatus Through Modulation of Dectin-1 Expression
Authors: MS Gresnigt, M Jaeger, RK Subbarao M, O Rasid, G Jouvion, C Fitting, WJG Melchers, TD Kanneganti, A Carvalho, O Ibrahim-Gr, FL van de Vee
Front Immunol, 2017-12-13;8(0):1777.
Species: Mouse
Sample Types: BALF
-
Treatment with a New Peroxisome Proliferator-Activated Receptor Gamma Agonist, Pyridinecarboxylic Acid Derivative, Increases Angiogenesis and Reduces Inflammatory Mediators in the Heart of Trypanosoma cruzi-Infected Mice
Authors: FN Penas, D Carta, G Dmytrenko, GA Mirkin, CP Modenutti, ÁC Cevey, MJ Rada, MG Ferlin, ME Sales, NB Goren
Front Immunol, 2017-12-11;8(0):1738.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Visfatin Triggers Anorexia and Body Weight Loss through Regulating the Inflammatory Response in the Hypothalamic Microglia
Authors: TH Tu, IS Nam-Goong, J Lee, S Yang, JG Kim
Mediators Inflamm., 2017-12-07;2017(0):1958947.
Species: Mouse
Sample Types: Cell Culture Supernates
-
CRISPR/Cas9 mediated mutation of mouse IL-1? nuclear localisation sequence abolishes expression
Authors: MJD Daniels, AD Adamson, N Humphreys, D Brough
Sci Rep, 2017-12-06;7(1):17077.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Kyungheechunggan-Tang-01, a New Herbal Medication, Suppresses LPS-Induced Inflammatory Responses through JAK/STAT Signaling Pathway in RAW 264.7 Macrophages
Authors: HS Han, E Jang, JS Shin, KS Inn, JH Lee, G Park, YP Jang, KT Lee
Evid Based Complement Alternat Med, 2017-11-29;2017(0):7383104.
Species: Mouse
Sample Types: Cell Culture Supernates
-
The influence of macrophage growth factors on Theiler's Murine Encephalomyelitis Virus (TMEV) infection and activation of macrophages
Authors: KM Schneider, NB Watson, SB Minchenber, PT Massa
Cytokine, 2017-08-09;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
The dataset describes: HIF-1 ? expression and LPS mediated cytokine production in MKP-1 deficient bone marrow derived murine macrophages
Authors: H Talwar, C Bauerfeld, Y Liu, L Samavati
Data Brief, 2017-07-20;14(0):56-61.
Species: Mouse
Sample Types: Cell Culture Supernates
-
MCPIP1 downregulation in clear cell renal cell carcinoma promotes vascularization and metastatic progression
Authors: P Marona, J Górka, Z Mazurek, W Wilk, J Rys, M Majka, J Jura, K Miekus
Cancer Res., 2017-07-17;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Paradoxical role of tumor necrosis factor on metabolic dysfunction and adipose tissue expansion in mice
Authors: LB Martins, MC Oliveira, Z Menezes-Ga, DF Rodrigues, JP Lana, LQ Vieira, MM Teixeira, AVM Ferreira
Nutrition, 2017-07-17;50(0):1-7.
Species: Mouse
Sample Types: Tissue Homogenates
-
Cathelicidins Inhibit Escherichia coli-Induced TLR2 and TLR4 Activation in a Viability-Dependent Manner
Authors: M Coorens, VAF Schneider, AM de Groot, A van Dijk, M Meijerink, JM Wells, MR Scheenstra, EJA Veldhuizen, HP Haagsman
J. Immunol., 2017-07-14;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Intramembrane attenuation of the TLR4-TLR6 dimer impairs receptor assembly and reduces microglia mediated neurodegeneration
Authors: L Shmuel-Gal, Y Klug, Z Porat, M Charni, B Zarmi, Y Shai
J. Biol. Chem., 2017-06-27;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Inducing maternal inflammation promotes leptin production in offspring but does not improve allergic symptoms in a mouse model of allergic rhinitis
Authors: A Imai, K Satoi, E Fujimoto, K Sato
Heliyon, 2017-06-22;3(6):e00327.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Combination of a high-fat diet with sweetened condensed milk exacerbates inflammation and insulin resistance induced by each separately in mice
Authors: LN Masi, AR Martins, AR Crisma, CL do Amaral, MR Davanso, TDA Serdan, RDC da Cunha d, MM Cruz, MIC Alonso-Val, RP Torres, J Mancini-Fi, JNB Pereira, MM da Silva R, EA Liberti, SM Hirabara, R Curi
Sci Rep, 2017-06-21;7(1):3937.
Species: Mouse
Sample Types: Tissue Homogenates
-
The GLP-1 analogue lixisenatide decreases atherosclerosis in insulin-resistant mice by modulating macrophage phenotype
Authors: Á Vinué, J Navarro, A Herrero-Ce, M García-Cub, I Andrés-Bla, S Martínez-H, JT Real, JF Ascaso, H González-N
Diabetologia, 2017-06-12;0(0):.
Species: Mouse
Sample Types: Plasma
-
The anti-inflammatory and immunomodulatory potential of braylin: Pharmacological properties and mechanisms by in silico, in vitro and in vivo approaches
Authors: RF Espírito-S, CS Meira, RDS Costa, OP Souza Filh, AF Evangelist, GHG Trossini, GM Ferreira, EDS Velozo, CF Villarreal, MB Pereira So
PLoS ONE, 2017-06-08;12(6):e0179174.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Elevated prostaglandin E2 post-bone marrow transplant mediates interleukin-1?-related lung injury
Authors: GJ Martínez-C, QM Taylor, CA Wilke, AB Podsiad, BB Moore
Mucosal Immunol, 2017-06-07;0(0):.
Species: Mouse
Sample Types: BALF
-
Influence of inflammation and nitric oxide upon platelet aggregation following deposition of diesel exhaust particles in the airways
Authors: E Smyth, A Solomon, MA Birrell, MJ Smallwood, PG Winyard, TD Tetley, M Emerson
Br. J. Pharmacol., 2017-05-27;0(0):.
Species: Mouse
Sample Types: BALF
-
Water-soluble chitosan inhibits nerve growth factor and attenuates allergic inflammation in mite allergen-induced allergic rhinitis
Authors: PC Chen, MH Hsieh, P Wen-ShuoKu, HF Kao, CL Hsu, JY Wang
J. Allergy Clin. Immunol., 2017-04-12;0(0):.
Species: Mouse
Sample Types: NLF
-
Chronic Toxoplasma gondii Infection Exacerbates Secondary Polymicrobial Sepsis
Authors: MC Souza, DM Fonseca, A Kanashiro, L Benevides, TS Medina, MS Dias, WA Andrade, G Bonfá, MAB Silva, A Gozzi, MC Borges, RT Gazzinelli, JC Alves-Filh, FQ Cunha, JS Silva
Front Cell Infect Microbiol, 2017-04-07;7(0):116.
Species: Mouse
Sample Types: Serum
-
Demyelination induced by oxidative stress is regulated by sphingosine 1-phosphate receptors
Authors: SA O'Sullivan, M Velasco-Es, KK Dev
Glia, 2017-04-04;0(0):.
-
NOX2 deficiency alters macrophage phenotype through an IL-10/STAT3 dependent mechanism: implications for traumatic brain injury
Authors: JP Barrett, RJ Henry, S Villapol, BA Stoica, A Kumar, MP Burns, AI Faden, DJ Loane
J Neuroinflammation, 2017-03-24;14(1):65.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Surface layer proteins from virulent Clostridium difficile ribotypes exhibit signatures of positive selection with consequences for innate immune response
Authors: M Lynch, TA Walsh, I Marszalows, AE Webb, M MacAogain, TR Rogers, H Windle, D Kelleher, MJ O'Connell, CE Loscher
BMC Evol. Biol, 2017-03-23;17(1):90.
Species: Mouse
Sample Types: Cell Culture Supernates
-
IL-24 Promotes Pseudomonas aeruginosa Keratitis in C57BL/6 Mouse Corneas
Authors: BX Ross, N Gao, X Cui, TJ Standiford, J Xu, FX Yu
J. Immunol, 2017-03-22;0(0):.
Species: Mouse
Sample Types: Tissue Homogenates
-
Combined toll-like receptor 3/7/9 deficiency on host cells results in T-cell-dependent control of tumour growth
Authors: JC Klein, K Moses, G Zelinskyy, S Sody, J Buer, S Lang, I Helfrich, U Dittmer, CJ Kirschning, S Brandau
Nat Commun, 2017-03-16;8(0):14600.
Species: Mouse
Sample Types: Tissue Homogenates
-
Cerium Oxide Nanoparticles in Lung Acutely Induce Oxidative Stress, Inflammation, and DNA Damage in Various Organs of Mice
Authors: A Nemmar, P Yuvaraju, S Beegam, MA Fahim, BH Ali
Oxid Med Cell Longev, 2017-03-14;2017(0):9639035.
Species: Mouse
Sample Types: Tissue Homogenates
-
The dynamic interacting landscape of MAPL reveals essential functions for SUMOylation in innate immunity
Authors: K Doiron, V Goyon, E Coyaud, S Rajapakse, B Raught, HM McBride
Sci Rep, 2017-03-07;7(1):107.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Intravitreal injection of anti-Interleukin (IL)-6 antibody attenuates experimental autoimmune uveitis in mice
Authors: J Tode, E Richert, S Koinzer, A Klettner, U Pickhinke, C Garbers, S Rose-John, B Nölle, J Roider
Cytokine, 2017-03-06;96(0):8-15.
Species: Mouse
Sample Types: Tissue Homogenates
-
Both anti-TNF and CTLA4 Ig treatments attenuate the disease severity of staphylococcal dermatitis in mice
Authors: M Na, W Wang, Y Fei, E Josefsson, A Ali, T Jin
PLoS ONE, 2017-03-06;12(3):e0173492.
Species: Mouse
Sample Types: Tissue Homogenates
-
Obesity-induced diet leads to weight gain, systemic metabolic alterations, adipose tissue inflammation, hepatic steatosis, and oxidative stress in gerbils (Meriones unguiculatus)
Authors: LL Ventura, NC Fortes, HC Santiago, MV Caliari, MA Gomes, DR Oliveira
PeerJ, 2017-03-02;5(0):e2967.
Species: Gerbil
Sample Types: Tissue Homogenates
-
Water-Pipe Smoke Exposure-Induced Circulatory Disturbances in Mice, and the Influence of Betaine Supplementation Thereon
Authors: A Nemmar, S Al-Salam, S Beegam, P Yuvaraju, A Oulhaj, BH Ali
Cell. Physiol. Biochem, 2017-02-27;41(3):1098-1112.
Species: Mouse
Sample Types: Plasma
-
CD74 Deficiency Mitigates Systemic Lupus Erythematosus-like Autoimmunity and Pathological Findings in Mice
Authors: Y Zhou, H Chen, L Liu, X Yu, GK Sukhova, M Yang, L Zhang, VC Kyttaris, GC Tsokos, IE Stillman, T Ichimura, JV Bonventre, P Libby, GP Shi
J. Immunol, 2017-02-20;0(0):.
Species: Mouse
Sample Types: Serum
-
2-Phenylnaphthalene Derivatives Inhibit Lipopolysaccharide-Induced Pro-Inflammatory Mediators by Downregulating of MAPK/NF-?B Pathways in RAW 264.7 Macrophage Cells
Authors: CF Chang, KC Liao, CH Chen
PLoS ONE, 2017-01-06;12(1):e0168945.
Species: Mouse
Sample Types: Cell Culture Supernates
-
p-Coumaroyl Anthocyanin Mixture Isolated from Tuber Epidermis of Solanum tuberosum Attenuates Reactive Oxygen Species and Pro-inflammatory Mediators by Suppressing NF-?B and STAT1/3 Signaling in LPS-Induced RAW264.7 Macrophages
Authors: HH Lee, SG Lee, JS Shin, HY Lee, K Yoon, YW Ji, DS Jang, KT Lee
Biol. Pharm. Bull., 2017-01-01;40(11):1894-1902.
Species: Mouse
Sample Types: Cell Culture Supernates
-
PROTECTIVE EFFECTS OF HUMAN AND MOUSE SOLUBLE SCAVENGER-LIKE CD6 LYMPHOCYTE RECEPTOR IN A LETHAL MODEL OF POLYMICROBIAL SEPSIS
Authors: Mario Martínez-F
Antimicrob. Agents Chemother, 2016-12-27;0(0):.
Species: Mouse
Sample Types: Plasma
-
Targeting dendritic cells to accelerate T-cell activation overcomes a bottleneck in tuberculosis vaccine efficacy
Nat Commun, 2016-12-22;7(0):13894.
Species: Mouse
Sample Types: Cell Culture Supernates
-
NADPH oxidase 4 regulates vascular inflammation in aging and atherosclerosis
Authors: Andrey Lozhkin
J. Mol. Cell. Cardiol, 2016-12-14;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Brazilian red propolis improves cutaneous wound healing suppressing inflammation-associated transcription factor NF?B
Authors: Flavia Regina Sobreira Corrêa
Biomed. Pharmacother, 2016-12-12;86(0):162-171.
Species: Mouse
Sample Types: Plasma
-
Sublethal doses of Dinophysistoxin-1 and Okadaic acid stimulate secretion of inflammatory factors on innate immune cells: Negative health consequences
Authors: Miguel Del Campo
Toxicon, 2016-12-09;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Critical role of TSLP-responsive mucosal dendritic cells in the induction of nasal antigen-specific IgA response
Mucosal Immunol, 2016-12-07;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Traditional medicine, Sobokchukeo?Tang, modulates the inflammatory response in adipocytes and macrophages
Mol Med Rep, 2016-12-07;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
NLRP12 negatively regulates proinflammatory cytokine production and host defense against Brucella abortus
Eur. J. Immunol., 2016-12-05;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Differential humoral and cellular immunity induced by vaccination using plasmid DNA and protein recombinant expressing the NS3 protein of dengue virus type 3
J. Biomed. Sci, 2016-12-01;23(1):85.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Toll-Like Receptor 2 recognizes Orientia tsutsugamushi and increases susceptibility to murine experimental scrub typhus
Infect Immun, 2016-11-18;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Expression of Par3 polarity protein correlates with poor prognosis in ovarian cancer
BMC Cancer, 2016-11-17;16(1):897.
Species: Human
Sample Types: Cell Culture Supernates
-
Immunogenic Dendritic Cell Generation from Pluripotent Stem Cells by Ectopic Expression of Runx3
Authors: Istvan Szatmari
J. Immunol., 2016-11-16;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Palmitate promotes inflammatory responses and cellular senescence in cardiac fibroblasts
Authors: Arne Yndestad
Biochim. Biophys. Acta, 2016-11-12;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Indoor secondary organic aerosols formation from ozonolysis of monoterpene: An example of d-limonene with ammonia and potential impacts on pulmonary inflammations
Authors: Rujin Huang
Sci. Total Environ., 2016-11-11;0(0):.
Species: Mouse
Sample Types: BALF
-
Chrysin promotes attenuation of depressive-like behavior and hippocampal dysfunction resulting from olfactory bulbectomy in mice
Authors: Silvana Peterini Boeira
Chem. Biol. Interact., 2016-11-03;0(0):.
Species: Mouse
Sample Types: Tissue Homogenates
-
Evaluating the effects of refined carbohydrate and fat diets with acute ethanol consumption using a mouse model of alcoholic liver injury
Authors: Ana Lúcia Brunialti-
J. Nutr. Biochem., 2016-09-22;39(0):93-100.
Species: Mouse
Sample Types: Tissue Homogenates
-
Poly-N-acetyl glucosamine production by Staphylococcus epidermidis cells increases their in vivo pro-inflammatory effect
Infect Immun, 2016-09-19;0(0):.
Species: Mouse
Sample Types: Serum
-
Klebsiella pneumoniae Siderophores Induce Inflammation, Bacterial Dissemination, and HIF-1? Stabilization during Pneumonia
MBio, 2016-09-13;7(5):.
Species: Mouse
Sample Types: Tissue Homogenates
-
Allergen-Induced IL-6 Regulates IL-9/IL-17A Balance in CD4+ T Cells in Allergic Airway Inflammation
J Immunol, 2016-08-29;197(7):2653-64.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Macrophagic control of the response to uropathogenic E. coli infection by regulation of iron retention in an IL-6-dependent manner
Authors: Nana Owusu-Boai
Immun Inflamm Dis, 2016-08-28;4(4):413-426.
Species: Mouse
Sample Types: Cell Culture Supernates
-
The circadian clock regulates inflammatory arthritis
FASEB J, 2016-08-03;0(0):.
Species: Mouse
Sample Types: Serum
-
Systemic Ablation of MMP9 Triggers Invasive Growth and Metastasis of Pancreatic Cancer via Deregulation of IL-6 Expression in the Bone Marrow
Mol Cancer Res, 2016-08-03;0(0):.
Species: Mouse
Sample Types: Plasma
-
Cannabinoid receptor 2 modulates susceptibility to experimental cerebral malaria through a CCL17-dependent mechanism
J Biol Chem, 2016-07-29;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Transcriptional and functional characterization of CD137L-dendritic cells identifies a novel dendritic cell phenotype
Sci Rep, 2016-07-19;6(0):29712.
Species: Human
Sample Types: Cell Culture Supernates
-
Contribution of the Ade Resistance-Nodulation-Cell Division-Type Efflux Pumps to Fitness and Pathogenesis of Acinetobacter baumannii
Authors: Eun-Jeong Yoon
MBio, 2016-05-31;7(3):.
Species: Mouse
Sample Types: BALF
-
Medial plantar nerve ligation as a novel model of neuropathic pain in mice: pharmacological and molecular characterization
Sci Rep, 2016-05-27;6(0):26955.
Species: Mouse
Sample Types: Tissue Homogenates
-
Neutrophil Attack Triggers Extracellular Trap-Dependent Candida Cell Wall Remodeling and Altered Immune Recognition
PLoS Pathog, 2016-05-25;12(5):e1005644.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Reducing hypoxia and inflammation during invasive pulmonary aspergillosis by targeting the Interleukin-1 receptor
Sci Rep, 2016-05-24;6(0):26490.
Species: Mouse
Sample Types: Tissue Homogenates
-
Loss of IL-22 inhibits autoantibody formation in collagen-induced arthritis in mice
Authors: OB Corneth, RM Reijmers, AM Mus, PS Asmawidjaj, JP van Hambur, N Papazian, JY Siegers, F Mourcin, R Amin, K Tarte, RW Hendriks, T Cupedo, E Lubberts
Eur J Immunol, 2016-05-12;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Gene Therapy Induces Antigen-Specific Tolerance in Experimental Collagen-Induced Arthritis
PLoS ONE, 2016-05-09;11(5):e0154630.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Immune Cell-Conditioned Media Suppress Prostate Cancer PC-3 Cell Growth Correlating With Decreased Proinflammatory/Anti-inflammatory Cytokine Ratios in the Media Using 5 Selected Crude Polysaccharides
Integr Cancer Ther, 2016-04-29;15(4):NP13-NP25.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Hemocyanins Stimulate Innate Immunity by Inducing Different Temporal Patterns of Proinflammatory Cytokine Expression in Macrophages
J Immunol, 2016-04-22;196(11):4650-62.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Infection-Mediated Priming of Phagocytes Protects against Lethal Secondary Aspergillus fumigatus Challenge
Authors: A Savers, O Rasid, M Parlato, M Brock, G Jouvion, B Ryffel, JM Cavaillon, G Eberl, O Ibrahim-Gr
PLoS ONE, 2016-04-14;11(4):e0153829.
Species: Mouse
Sample Types: Tissue Homogenates
-
The dual S1PR1/S1PR5 drug BAF312 (Siponimod) attenuates demyelination in organotypic slice cultures.
Authors: O'Sullivan C, Schubart A, Mir A, Dev K
J Neuroinflammation, 2016-02-08;13(1):31.
Species: Mouse
Sample Types: Cell Culture Supernates
-
C1P Attenuates Lipopolysaccharide-Induced Acute Lung Injury by Preventing NF-?B Activation in Neutrophils
J Immunol, 2016-01-22;196(5):2319-26.
Species: Mouse
Sample Types: BALF
-
Jucara pulp supplementation improves glucose tolerance in mice.
Authors: Oyama L, Silva F, Carnier J, de Miranda D, Santamarina A, Ribeiro E, Oller do Nascimento C, de Rosso V
Diabetol Metab Syndr, 2016-01-22;8(0):8.
Species: Mouse
Sample Types: Tissue Homogenates
-
Human beta-D-3 Exacerbates MDA5 but Suppresses TLR3 Responses to the Viral Molecular Pattern Mimic Polyinosinic:Polycytidylic Acid.
Authors: Semple F, MacPherson H, Webb S, Kilanowski F, Lettice L, McGlasson S, Wheeler A, Chen V, Millhauser G, Melrose L, Davidson D, Dorin J
PLoS Genet, 2015-12-08;11(12):e1005673.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Activation of AMP-Activated Protein Kinase by Adenine Alleviates TNF-Alpha-Induced Inflammation in Human Umbilical Vein Endothelial Cells.
Authors: Cheng Y, Young G, Lin J, Jang H, Chen C, Nong J, Chen P, Kuo C, Kao S, Liang Y, Chen H
PLoS ONE, 2015-11-06;10(11):e0142283.
Species: Human
Sample Types: Cell Culture Supernates
-
C1q Deficiency Promotes Pulmonary Vascular Inflammation and Enhances the Susceptibility of the Lung Endothelium to Injury.
Authors: Shah D, Romero F, Zhu Y, Duong M, Sun J, Walsh K, Summer R
J Biol Chem, 2015-10-20;290(49):29642-51.
Species: Mouse
Sample Types: BALF
-
Glutathione peroxidase 4 prevents necroptosis in mouse erythroid precursors.
Authors: Canli O, Alankus Y, Grootjans S, Vegi N, Hultner L, Hoppe P, Schroeder T, Vandenabeele P, Bornkamm G, Greten F
Blood, 2015-10-13;127(1):139-48.
Species: Mouse
Sample Types: Serum
-
Des-Aspartate-Angiotensin I Attenuates Mortality of Mice Exposed to Gamma Radiation via a Novel Mechanism of Action.
Authors: Wang H, Sethi G, Loke W, Sim M
PLoS ONE, 2015-09-17;10(9):e0138009.
Species: Mouse
Sample Types: Plasma
-
Effects of High-Intensity Swimming on Lung Inflammation and Oxidative Stress in a Murine Model of DEP-Induced Injury.
Authors: Avila L, Bruggemann T, Bobinski F, da Silva M, Oliveira R, Martins D, Mazzardo-Martins L, Duarte M, de Souza L, Dafre A, Vieira R, Santos A, Bonorino K, Hizume Kunzler D
PLoS ONE, 2015-09-02;10(9):e0137273.
Species: Mouse
Sample Types: Tissue Homogenates
-
Cellular FLIP Inhibits Myeloid Cell Activation by Suppressing Selective Innate Signaling.
Authors: Wu Y, Wu Y, Mo S, Hsiao H, He Y, Lai M
J Immunol, 2015-08-03;195(6):2612-23.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Differential Immunometabolic Phenotype in Th1 and Th2 Dominant Mouse Strains in Response to High-Fat Feeding.
Authors: Jovicic N, Jeftic I, Jovanovic I, Radosavljevic G, Arsenijevic N, Lukic M, Pejnovic N
PLoS ONE, 2015-07-28;10(7):e0134089.
Species: Mouse
Sample Types: Tissue Homogenates
-
Alveolar Epithelial A2B Adenosine Receptors in Pulmonary Protection during Acute Lung Injury.
Authors: Hoegl S, Brodsky K, Blackburn M, Karmouty-Quintana H, Zwissler B, Eltzschig H
J Immunol, 2015-07-17;195(4):1815-24.
Species: Mouse
Sample Types: BALF
-
Low dietary iron intake restrains the intestinal inflammatory response and pathology of enteric infection by food-borne bacterial pathogens.
Authors: Kortman G, Mulder M, Richters T, Shanmugam N, Trebicka E, Boekhorst J, Timmerman H, Roelofs R, Wiegerinck E, Laarakkers C, Swinkels D, Bolhuis A, Cherayil B, Tjalsma H
Eur J Immunol, 2015-06-23;45(9):2553-67.
Species: Mouse
Sample Types: Cell Culture Supernates
-
The generation of macrophages with anti-inflammatory activity in the absence of STAT6 signaling.
Authors: Fleming B, Chandrasekaran P, Dillon L, Dalby E, Suresh R, Sarkar A, El-Sayed N, Mosser D
J Leukoc Biol, 2015-06-05;98(3):395-407.
Species: Mouse
Sample Types: Cell Culture Supernates
-
The Effect of OSM on MC3T3-E1 Osteoblastic Cells in Simulated Microgravity with Radiation.
Authors: Goyden J, Tawara K, Hedeen D, Willey J, Oxford J, Jorcyk C
PLoS ONE, 2015-06-01;10(6):e0127230.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Pyruvate dehydrogenase kinase 1 participates in macrophage polarization via regulating glucose metabolism.
Authors: Tan Z, Xie N, Cui H, Moellering D, Abraham E, Thannickal V, Liu G
J Immunol, 2015-05-11;194(12):6082-9.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Influenza A virus-dependent remodeling of pulmonary clock function in a mouse model of COPD.
Authors: Sundar, Isaac K, Ahmad, Tanveer, Yao, Hongwei, Hwang, Jae-woon, Gerloff, Janice, Lawrence, B Paige, Sellix, Michael, Rahman, Irfan
Sci Rep, 2015-04-29;4(0):9927.
Species: Mouse
Sample Types: BALF
-
Endoplasmic reticulum stress-induced IRE1alpha activation mediates cross-talk of GSK-3beta and XBP-1 to regulate inflammatory cytokine production.
Authors: Kim S, Joe Y, Kim H, Kim Y, Jeong S, Pae H, Ryter S, Surh Y, Chung H
J Immunol, 2015-03-27;194(9):4498-506.
Species: Mouse
Sample Types: Serum
-
Innate immune response to Streptococcus pyogenes depends on the combined activation of TLR13 and TLR2.
Authors: Fieber C, Janos M, Koestler T, Gratz N, Li X, Castiglia V, Aberle M, Sauert M, Wegner M, Alexopoulou L, Kirschning C, Chen Z, von Haeseler A, Kovarik P
PLoS ONE, 2015-03-10;10(3):e0119727.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Simultaneous and dose dependent melanoma cytotoxic and immune stimulatory activity of betulin.
Authors: Pfarr K, Danciu C, Arlt O, Neske C, Dehelean C, Pfeilschifter J, Radeke H
PLoS ONE, 2015-03-10;10(3):e0118802.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Apolipoprotein E promotes subretinal mononuclear phagocyte survival and chronic inflammation in age-related macular degeneration.
Authors: Levy O, Calippe B, Lavalette S, Hu S, Raoul W, Dominguez E, Housset M, Paques M, Sahel J, Bemelmans A, Combadiere C, Guillonneau X, Sennlaub F
EMBO Mol Med, 2015-02-01;7(2):211-26.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Recombinant thrombomodulin inhibits lipopolysaccharide-induced inflammatory response by blocking the functions of CD14.
Authors: Ma C, Chang W, Shi G, Chang B, Cheng S, Shih Y, Wu H
J Immunol, 2015-01-21;194(4):1905-15.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Lysostaphin-coated titan-implants preventing localized osteitis by Staphylococcus aureus in a mouse model.
Authors: Windolf C, Logters T, Scholz M, Windolf J, Flohe S
PLoS ONE, 2014-12-23;9(12):e115940.
Species: Mouse
Sample Types: BALF
-
Interleukin-15 modulates adipose tissue by altering mitochondrial mass and activity.
Authors: Barra, Nicole G, Palanivel, Rengasam, Denou, Emmanuel, Chew, Marianne, Gillgrass, Amy, Walker, Tina D, Kong, Josh, Richards, Carl D, Jordana, Manel, Collins, Stephen, Trigatti, Bernardo, Holloway, Alison C, Raha, Sandeep, Steinberg, Gregory, Ashkar, Ali A
PLoS ONE, 2014-12-17;9(12):e114799.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Role of IL-1β in experimental cystic fibrosis upon P. aeruginosa infection.
PLoS ONE, 2014-12-12;9(12):e114884.
Species: Mouse
Sample Types: Tissue Homogenates
-
Severe neutrophil-dominated inflammation and enhanced myelopoiesis in IL-33-overexpressing CMV/IL33 mice.
Authors: Talabot-Ayer D, Martin P, Vesin C, Seemayer C, Vigne S, Gabay C, Palmer G
J Immunol, 2014-12-10;194(2):750-60.
Species: Mouse
Sample Types: Tissue Homogenates
-
Thrombospondin-1 restrains neutrophil granule serine protease function and regulates the innate immune response during Klebsiella pneumoniae infection.
Authors: Zhao Y, Olonisakin T, Xiong Z, Hulver M, Sayeed S, Yu M, Gregory A, Kochman E, Chen B, Mallampalli R, Sun M, Silverstein R, Stolz D, Shapiro S, Ray A, Ray P, Lee J
Mucosal Immunol, 2014-12-10;8(4):896-905.
Species: Mouse
Sample Types: Tissue Homogenates
-
The inability of wild-type rabies virus to activate dendritic cells is dependent on the glycoprotein and correlates with its low level of the de novo-synthesized leader RNA.
Authors: Yang Y, Huang Y, Gnanadurai C, Cao S, Liu X, Cui M, Fu Z
J Virol, 2014-12-03;89(4):2157-69.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Negative regulation of melanoma differentiation-associated gene 5 (MDA5)-dependent antiviral innate immune responses by Arf-like protein 5B.
Authors: Kitai Y, Takeuchi O, Kawasaki T, Ori D, Sueyoshi T, Murase M, Akira S, Kawai T
J Biol Chem, 2014-12-01;290(2):1269-80.
Species: Mouse
Sample Types: Cell Culture Supernates
-
The methyltransferase Setdb2 mediates virus-induced susceptibility to bacterial superinfection.
Authors: Schliehe C, Flynn E, Vilagos B, Richson U, Swaminathan S, Bosnjak B, Bauer L, Kandasamy R, Griesshammer I, Kosack L, Schmitz F, Litvak V, Sissons J, Lercher A, Bhattacharya A, Khamina K, Trivett A, Tessarollo L, Mesteri I, Hladik A, Merkler D, Kubicek S, Knapp S, Epstein M, Symer D, Aderem A, Bergthaler A
Nat Immunol, 2014-11-24;16(1):67-74.
Species: Mouse
Sample Types: BALF
-
Cessation of CCL2 inhibition accelerates breast cancer metastasis by promoting angiogenesis.
Authors: Bonapace L, Coissieux M, Wyckoff J, Mertz K, Varga Z, Junt T, Bentires-Alj M
Nature, 2014-10-22;515(7525):130-3.
Species: Mouse
Sample Types: Cell Culture Supernates
-
No Impairment in host defense against Streptococcus pneumoniae in obese CPEfat/fat mice.
Authors: Mancuso P, O Brien E, Prano J, Goel D, Aronoff D
PLoS ONE, 2014-09-09;9(9):e106420.
Species: Mouse
Sample Types: BALF
-
Murine lung injury caused by Leptospira interrogans glycolipoprotein, a specific Na/K-ATPase inhibitor.
Authors: Goncalves-de-Albuquerque C, Burth P, Silva A, de Moraes I, Oliveira F, Santelli R, Freire A, de Lima G, da Silva E, da Silva C, Morandi V, Bozza P, Younes-Ibrahim M, de Castro Faria Neto H, de Castro Faria M
Respir Res, 2014-08-14;15(0):93.
Species: Mouse
Sample Types: BALF
-
TIR-domain-containing adapter-inducing interferon-beta (TRIF) regulates Th17-mediated intestinal immunopathology in colitis.
Authors: Kanagavelu S, Flores C, Termini J, Riveron R, Romero L, Chung K, Ruiz J, Hyun J, Yuan X, Dagvadorj J, Fukata M
Mucosal Immunol, 2014-07-30;8(2):296-306.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Micheliolide, a new sesquiterpene lactone that inhibits intestinal inflammation and colitis-associated cancer.
Authors: Viennois E, Xiao B, Ayyadurai S, Wang L, Wang P, Zhang Q, Chen Y, Merlin D
Lab Invest, 2014-07-28;94(9):950-65.
Species: Mouse
Sample Types: Cell Culture Supernates
-
The innate immune response elicited by Group A Streptococcus is highly variable among clinical isolates and correlates with the emm type.
Authors: Dinis M, Plainvert C, Kovarik P, Longo M, Fouet A, Poyart C
PLoS ONE, 2014-07-03;9(7):e101464.
Species: Mouse
Sample Types: Cell Culture Supernates
-
25-Hydroxycholesterol acts as an amplifier of inflammatory signaling.
Authors: Gold E, Diercks A, Podolsky I, Podyminogin R, Askovich P, Treuting P, Aderem A
Proc Natl Acad Sci U S A, 2014-07-03;111(29):10666-71.
Species: Mouse
Sample Types: BALF
-
LPS induces the degradation of programmed cell death protein 4 (PDCD4) to release Twist2, activating c-Maf transcription to promote interleukin-10 production.
Authors: van den Bosch M, Palsson-Mcdermott E, Johnson D, O'Neill L
J Biol Chem, 2014-06-30;289(33):22980-90.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Role of lysosomes in silica-induced inflammasome activation and inflammation in absence of MARCO.
Authors: Biswas R, Hamilton R, Holian A
J Immunol Res, 2014-06-26;2014(0):304180.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Palmitoylethanolamide stimulates phagocytosis of Escherichia coli K1 by macrophages and increases the resistance of mice against infections.
Authors: Redlich S, Ribes S, Schutze S, Nau R
J Neuroinflammation, 2014-06-14;11(0):108.
Species: Mouse
Sample Types: Tissue Homogenates
-
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) prevents lipopolysaccharide (LPS)-induced, sepsis-related severe acute lung injury in mice.
Authors: Takaoka, Yuki, Goto, Shigeru, Nakano, Toshiaki, Tseng, Hui-Peng, Yang, Shih-Min, Kawamoto, Seiji, Ono, Kazuhisa, Chen, Chao-Lon
Sci Rep, 2014-06-06;4(0):5204.
Species: Mouse
Sample Types: Serum
-
Anti-inflammatory effects of Perilla frutescens leaf extract on lipopolysaccharide-stimulated RAW264.7 cells.
Authors: Huang B, Lin C, Chen Y, Kao S
Mol Med Rep, 2014-06-05;10(2):1077-83.
Species: Mouse
Sample Types: Cell Culture Supernates
-
The inflammasome pyrin contributes to pertussis toxin-induced IL-1beta synthesis, neutrophil intravascular crawling and autoimmune encephalomyelitis.
Authors: Dumas A, Amiable N, de Rivero Vaccari J, Chae J, Keane R, Lacroix S, Vallieres L
PLoS Pathog, 2014-05-29;10(5):e1004150.
Species: Mouse
Sample Types: Peritoneal Fluid
-
Development and characterization of a long-term murine model of Streptococcus pneumoniae infection of the lower airways.
Authors: Haste L, Hulland K, Bolton S, Yesilkaya H, McKechnie K, Andrew P
Infect Immun, 2014-05-27;82(8):3289-98.
Species: Mouse
Sample Types: BALF
-
miR-27a regulates inflammatory response of macrophages by targeting IL-10.
Authors: Xie N, Cui H, Banerjee S, Tan Z, Salomao R, Fu M, Abraham E, Thannickal V, Liu G
J Immunol, 2014-05-16;193(1):327-34.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Role of the aryl hydrocarbon receptor in the immune response profile and development of pathology during Plasmodium berghei Anka infection.
Authors: Brant F, Miranda A, Esper L, Rodrigues D, Kangussu L, Bonaventura D, Soriani F, Pinho V, Souza D, Rachid M, Weiss L, Tanowitz H, Teixeira M, Teixeira A, Machado F
Infect Immun, 2014-05-12;82(8):3127-40.
Species: Mouse
Sample Types: Tissue Homogenates
-
Heat shock protein 60: an endogenous inducer of dopaminergic cell death in Parkinson disease.
Authors: Noelker C, Morel L, Osterloh A, Alvarez-Fischer D, Lescot T, Breloer M, Gold M, Oertel W, Henze C, Michel P, Dodel R, Lu L, Hirsch E, Hunot S, Hartmann A
J Neuroinflammation, 2014-05-08;11(0):86.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Assessing the role of STAT3 in DC differentiation and autologous DC immunotherapy in mouse models of GBM.
Authors: Assi H, Espinosa J, Suprise S, Sofroniew M, Doherty R, Zamler D, Lowenstein P, Castro M
PLoS ONE, 2014-05-07;9(5):e96318.
Species: Mouse
Sample Types: Cell Culture Supernates
-
A new protective role for S100A9 in regulation of neutrophil recruitment during invasive pneumococcal pneumonia.
Authors: De Filippo K, Neill D, Mathies M, Bangert M, McNeill E, Kadioglu A, Hogg N
FASEB J, 2014-04-28;28(8):3600-8.
Species: Mouse
Sample Types: Tissue Homogenates
-
Pulmonary immune responses to 2009 pandemic influenza A (H1N1) virus in mice.
Authors: Lv J, Wang D, Hua Y, Pei S, Wang J, Hu W, Wang X, Jia N, Jiang Q
BMC Infect Dis, 2014-04-12;14(0):197.
Species: Mouse
Sample Types: Tissue Homogenates
-
Peripheral inflammation is associated with remote global gene expression changes in the brain.
Authors: Thomson, Carolyn, McColl, Alison, Cavanagh, Jonathan, Graham, Gerard J
J Neuroinflammation, 2014-04-08;11(0):73.
Species: Mouse
Sample Types: Plasma
-
Vitamin d deficiency reduces the immune response, phagocytosis rate, and intracellular killing rate of microglial cells.
Authors: Djukic M, Onken M, Schutze S, Redlich S, Gotz A, Hanisch U, Bertsch T, Ribes S, Hanenberg A, Schneider S, Bollheimer C, Sieber C, Nau R
Infect Immun, 2014-03-31;82(6):2585-94.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Animal model of respiratory syncytial virus: CD8+ T cells cause a cytokine storm that is chemically tractable by sphingosine-1-phosphate 1 receptor agonist therapy.
Authors: Walsh K, Teijaro J, Brock L, Fremgen D, Collins P, Rosen H, Oldstone M
J Virol, 2014-03-26;88(11):6281-93.
Species: Mouse
Sample Types: BALF
-
Gene and protein expression in response to different growth temperatures and oxygen availability in Burkholderia thailandensis.
Authors: Peano C, Chiaramonte F, Motta S, Pietrelli A, Jaillon S, Rossi E, Consolandi C, Champion O, Michell S, Freddi L, Falciola L, Basilico F, Garlanda C, Mauri P, De Bellis G, Landini P
PLoS ONE, 2014-03-26;9(3):e93009.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Toll-like receptor 9 deficiency protects mice against Pseudomonas aeruginosa lung infection.
Authors: Benmohamed F, Medina M, Wu Y, Maschalidi S, Jouvion G, Guillemot L, Chignard M, Manoury B, Touqui L
PLoS ONE, 2014-03-04;9(3):e90466.
Species: Mouse
Sample Types: BALF
-
Mapping the innate signaling cascade essential for cytokine storm during influenza virus infection.
Authors: Teijaro J, Walsh K, Rice S, Rosen H, Oldstone M
Proc Natl Acad Sci U S A, 2014-02-26;111(10):3799-804.
Species: Mouse
Sample Types: BALF
-
S100A9 knockout decreases the memory impairment and neuropathology in crossbreed mice of Tg2576 and S100A9 knockout mice model.
Authors: Kim H, Chang K, Ha T, Kim J, Ha S, Shin K, Moon C, Nacken W, Kim H, Suh Y
PLoS ONE, 2014-02-25;9(2):e88924.
Species: Mouse
Sample Types: Tissue Homogenates
-
Unique macrophages different from M1/M2 macrophages inhibit T cell mitogenesis while upregulating Th17 polarization.
Authors: Tatano Y, Shimizu T, Tomioka H
Sci Rep, 2014-02-20;4(0):4146.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Signaling via tumor necrosis factor receptor 1 but not Toll-like receptor 2 contributes significantly to hydrosalpinx development following Chlamydia muridarum infection.
Authors: Dong X, Liu Y, Chang X, Lei L, Zhong G
Infect Immun, 2014-02-18;82(5):1833-9.
Species: Mouse
Sample Types: Cell Culture Supernates
-
RNA:DNA hybrids are a novel molecular pattern sensed by TLR9.
Authors: Rigby R, Webb L, Mackenzie K, Li Y, Leitch A, Reijns M, Lundie R, Revuelta A, Davidson D, Diebold S, Modis Y, MacDonald A, Jackson A
EMBO J, 2014-02-10;33(6):542-58.
Species: Mouse
Sample Types: Cell Culture Supernates
-
miR-21 attenuates lipopolysaccharide-induced lipid accumulation and inflammatory response: potential role in cerebrovascular disease.
Authors: Feng J, Li A, Deng J, Yang Y, Dang L, Ye Y, Li Y, Zhang W
Lipids Health Dis, 2014-02-07;13(0):27.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Protective or deleterious role of scavenger receptors SR-A and CD36 on host resistance to Staphylococcus aureus depends on the site of infection.
Authors: Blanchet C, Jouvion G, Fitting C, Cavaillon J, Adib-Conquy M
PLoS ONE, 2014-01-31;9(1):e87927.
Species: Mouse
Sample Types: BALF
-
PPAR-gamma/IL-10 axis inhibits MyD88 expression and ameliorates murine polymicrobial sepsis.
Authors: Ferreira A, Sisti F, Sonego F, Wang S, Filgueiras L, Brandt S, Serezani A, Du H, Cunha F, Alves-Filho J, Serezani C
J Immunol, 2014-01-31;192(5):2357-65.
Species: Mouse
Sample Types: Serum
-
Artesunate reduces serum lipopolysaccharide in cecal ligation/puncture mice via enhanced LPS internalization by macrophages through increased mRNA expression of scavenger receptors.
Authors: Li, Bin, Yu, Mengchen, Pan, Xichun, Ren, Chuanlia, Peng, Wei, Li, Xiaoli, Jiang, Weiwei, Zheng, Jiang, Zhou, Hong
Int J Mol Sci, 2014-01-16;15(1):1143-61.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Promyelocytic leukemia protein interacts with the apoptosis-associated speck-like protein to limit inflammasome activation.
Authors: Dowling J, Becker C, Bourke N, Corr S, Connolly D, Quinn S, Pandolfi P, Mansell A, O'Neill L
J Biol Chem, 2014-01-09;289(10):6429-37.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Sustained Na+/H+ exchanger activation promotes gliotransmitter release from reactive hippocampal astrocytes following oxygen-glucose deprivation.
Authors: Cengiz P, Kintner D, Chanana V, Yuan H, Akture E, Kendigelen P, Begum G, Fidan E, Uluc K, Ferrazzano P, Sun D
PLoS ONE, 2014-01-02;9(1):e84294.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Myeloid cell sirtuin-1 expression does not alter host immune responses to Gram-negative endotoxemia or Gram-positive bacterial infection.
Authors: Crotty Alexander, Laura E, Marsh, Brenda J, Timmer, Anjuli M, Lin, Ann E, Zainabadi, Kayvan, Czopik, Agnieszk, Guarente, Leonard, Nizet, Victor
PLoS ONE, 2013-12-26;8(12):e84481.
Species: Mouse
Sample Types: Plasma
-
A pseudopterane diterpene isolated from the octocoral Pseudopterogorgia acerosa inhibits the inflammatory response mediated by TLR-ligands and TNF-alpha in macrophages.
Authors: Gonzalez Y, Doens D, Santamaria R, Ramos M, Restrepo C, Barros de Arruda L, Lleonart R, Gutierrez M, Fernandez P
PLoS ONE, 2013-12-16;8(12):e84107.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Smooth muscle cells relay acute pulmonary inflammation via distinct ADAM17/ErbB axes.
Authors: Dreymueller D, Martin C, Schumacher J, Groth E, Boehm J, Reiss L, Uhlig S, Ludwig A
J Immunol, 2013-12-16;192(2):722-31.
Species: Mouse
Sample Types: BALF
-
Lack of platelet-activating factor receptor protects mice against diet-induced adipose inflammation and insulin-resistance despite fat pad expansion.
Authors: Menezes-Garcia Z, Oliveira M, Lima R, Soriani F, Cisalpino D, Botion L, Teixeira M, Souza D, Ferreira A
Obesity (Silver Spring), 2013-12-14;22(3):663-72.
Species: Mouse
Sample Types: Tissue Homogenates
-
Defining the range of pathogens susceptible to Ifitm3 restriction using a knockout mouse model.
Authors: Everitt, Aaron R, Clare, Simon, McDonald, Jacqueli, Kane, Leanne, Harcourt, Katherin, Ahras, Malika, Lall, Amar, Hale, Christin, Rodgers, Angela, Young, Douglas, Haque, Ashraful, Billker, Oliver, Tregoning, John S, Dougan, Gordon, Kellam, Paul
PLoS ONE, 2013-11-21;8(11):e80723.
Species: Mouse
Sample Types: BALF
-
Calcineurin-Rcan1 interaction contributes to stem cell factor-mediated mast cell activation.
Authors: Wu Z, Li Y, MacNeil A, Junkins R, Berman J, Lin T
J Immunol, 2013-11-11;191(12):5885-94.
Species: Mouse
Sample Types: Cell Culture Supernates
-
A2B adenosine receptors prevent insulin resistance by inhibiting adipose tissue inflammation via maintaining alternative macrophage activation.
Authors: Csoka B, Koscso B, Toro G, Kokai E, Virag L, Nemeth Z, Pacher P, Bai P, Hasko G
Diabetes, 2013-11-05;63(3):850-66.
Species: Mouse
Sample Types: Plasma
-
Mannose receptor 1 mediates cellular uptake and endosomal delivery of CpG-motif containing oligodeoxynucleotides.
Authors: Moseman, Annie Pa, Moseman, E Ashley, Schworer, Stephen, Smirnova, Irina, Volkova, Tatyana, von Andrian, Ulrich, Poltorak, Alexande
J Immunol, 2013-11-01;191(11):5615-24.
Species: Mouse
Sample Types: Cell Culture Supernates
-
ER stress-mediated regulation of immune function under glucose-deprived condition in glial cells: up- and down-regulation of PGE2 + IFNgamma-induced IL-6 and iNOS expressions.
Authors: Hosoi T, Oba T, Ozawa K
Biochem Biophys Res Commun, 2013-10-29;441(2):525-8.
Species: Mouse
Sample Types: Cell Culture Supernates
-
TXNIP deficiency exacerbates endotoxic shock via the induction of excessive nitric oxide synthesis.
Authors: Park Y, Yoon S, Suh H, Kim D, Park J, Jung H, Kim T, Yoon S, Min J, Na H, Lee S, Lee H, Lee Y, Lee H, Choi I
PLoS Pathog, 2013-10-03;9(10):e1003646.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Activated factor X signaling via protease-activated receptor 2 suppresses pro-inflammatory cytokine production from lipopolysaccharide-stimulated myeloid cells.
Authors: Gleeson E, O'Donnell J, Hams E, Ni Ainle F, Kenny B, Fallon P, Preston R
Haematologica, 2013-07-19;99(1):185-93.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Toll-like receptor 6 senses Mycobacterium avium and is required for efficient control of mycobacterial infection.
Authors: Marinho F, de Paula R, Mendes A, de Almeida L, Gomes M, Carvalho N, Oliveira F, Caliari M, Oliveira S
Eur J Immunol, 2013-06-21;43(9):2373-85.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Bee venom and its component apamin as neuroprotective agents in a Parkinson disease mouse model.
Authors: Alvarez-Fischer D, Noelker C, Vulinovic F, Grunewald A, Chevarin C, Klein C, Oertel W, Hirsch E, Michel P, Hartmann A
PLoS ONE, 2013-04-18;8(4):e61700.
Species: Mouse
Sample Types: Tissue Homogenates
-
Intestinal CCL11 and eosinophilic inflammation is regulated by myeloid cell-specific RelA/p65 in mice.
Authors: Waddell A, Ahrens R, Tsai Y, Sherrill J, Denson L, Steinbrecher K, Hogan S
J Immunol, 2013-04-05;190(9):4773-85.
Species: Mouse
Sample Types: Cell Culture Supernates
-
A novel murine model of rhinoscleroma identifies Mikulicz cells, the disease signature, as IL-10 dependent derivatives of inflammatory monocytes.
Authors: Fevre C, Almeida A, Taront S, Pedron T, Huerre M, Prevost M, Kieusseian A, Cumano A, Brisse S, Sansonetti P, Tournebize R
EMBO Mol Med, 2013-04-01;5(4):516-30.
Species: Mouse
Sample Types: Tissue Homogenates
-
Ghrelin inhibits LPS-induced release of IL-6 from mouse dopaminergic neurones.
Authors: Beynon A, Brown M, Wright R, Rees M, Sheldon I, Davies J
J Neuroinflammation, 2013-03-19;10(0):40.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Syntaxin binding protein 1 is not required for allergic inflammation via IgE-mediated mast cell activation.
Authors: Wu Z, MacNeil A, Berman J, Lin T
PLoS ONE, 2013-03-06;8(3):e58560.
Species: Mouse
Sample Types: Cell Culture Supernates
-
The novel cytokine interleukin-33 activates acinar cell proinflammatory pathways and induces acute pancreatic inflammation in mice.
Authors: Kempuraj D, Twait E, Williard D, Yuan Z, Meyerholz D, Samuel I
PLoS ONE, 2013-02-13;8(2):e56866.
Species: Mouse
Sample Types: Tissue Homogenates
-
IRAK-M mediates Toll-like receptor/IL-1R-induced NFkappaB activation and cytokine production.
Authors: Zhou H, Yu M, Fukuda K, Im J, Yao P, Cui W, Bulek K, Zepp J, Wan Y, Kim T, Yin W, Ma V, Thomas J, Gu J, Wang J, DiCorleto P, Fox P, Qin J, Li X
EMBO J, 2013-02-01;32(4):583-96.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Genetic deletion of the HIF-1alpha isoform I.1 in T cells enhances antibacterial immunity and improves survival in a murine peritonitis model.
Authors: Georgiev P, Belikoff B, Hatfield S, Ohta A, Sitkovsky M, Lukashev D
Eur J Immunol, 2013-01-31;43(3):655-66.
Species: Mouse
Sample Types: Serum
-
Sulfatide attenuates experimental Staphylococcus aureus sepsis through a CD1d-dependent pathway.
Authors: Kwiecinski J, Rhost S, Lofbom L, Blomqvist M, Mansson J, Cardell S, Jin T
Infect Immun, 2013-01-22;81(4):1114-20.
Species: Mouse
Sample Types: Plasma
-
Role of OGR1 in myeloid-derived cells in prostate cancer.
Authors: Yan, L, Singh, L S, Zhang, L, Xu, Y
Oncogene, 2012-12-10;33(2):157-64.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Proteolytic processing regulates Toll-like receptor 3 stability and endosomal localization.
Authors: Qi, Rongsu, Singh, Divyendu, Kao, C Cheng
J Biol Chem, 2012-08-03;287(39):32617-29.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Rosiglitazone improves survival and hastens recovery from pancreatic inflammation in obese mice.
Authors: Pini M, Rhodes DH, Castellanos KJ
PLoS ONE, 2012-07-16;7(7):e40944.
Species: Mouse
Sample Types: Plasma
-
Lipocalin 2 deficiency dysregulates iron homeostasis and exacerbates endotoxin-induced sepsis.
J. Immunol., 2012-07-11;189(4):1911-9.
Species: Mouse
Sample Types: Serum
-
Influence of hypoxia-inducible factor 1-alpha on dendritic cell differentiation and migration.
Authors: Kohler T, Reizis B, Johnson RS, Weighardt H, Forster I
Eur. J. Immunol., 2012-05-01;42(5):1226-36.
Species: Mouse
Sample Types: Cell Culture Supernates
-
The role of alveolar epithelial cells in initiating and shaping pulmonary immune responses: communication between innate and adaptive immune systems.
Authors: Chuquimia OD, Petursdottir DH, Rahman MJ, Hartl K, Singh M, Fernandez C
PLoS ONE, 2012-02-29;7(2):e32125.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Role of Toll interleukin-1 receptor (IL-1R) 8, a negative regulator of IL-1R/Toll-like receptor signaling, in resistance to acute Pseudomonas aeruginosa lung infection.
Authors: Veliz Rodriguez T, Moalli F, Polentarutti N, Paroni M, Bonavita E, Anselmo A, Nebuloni M, Mantero S, Jaillon S, Bragonzi A, Mantovani A, Riva F, Garlanda C
Infect. Immun., 2011-10-24;80(1):100-9.
Species: Mouse
Sample Types: Serum
-
Local delivery of GM-CSF protects mice from lethal pneumococcal pneumonia.
Authors: Steinwede K, Tempelhof O, Bolte K, Maus R, Bohling J, Ueberberg B, Langer F, Christman JW, Paton JC, Ask K, Maharaj S, Kolb M, Gauldie J, Welte T, Maus UA
J. Immunol., 2011-10-14;187(10):5346-56.
Species: Mouse
Sample Types: BALF
-
Endothelial cells are central orchestrators of cytokine amplification during influenza virus infection.
Authors: Teijaro JR, Walsh KB, Cahalan S, Fremgen DM, Roberts E, Scott F, Martinborough E, Peach R, Oldstone MB, Rosen H
Cell, 2011-09-16;146(6):980-91.
Species: Mouse
Sample Types: BALF
-
Transcriptomic analysis of host immune and cell death responses associated with the influenza A virus PB1-F2 protein.
Authors: Le Goffic R, Leymarie O, Chevalier C, Rebours E, Da Costa B, Vidic J, Descamps D, Sallenave JM, Rauch M, Samson M, Delmas B
PLoS Pathog., 2011-08-25;7(8):e1002202.
Species: Mouse
Sample Types: BALF
-
Pseudomonas aeruginosa toxin ExoU induces a PAF-dependent impairment of alveolar fibrin turnover secondary to enhanced activation of coagulation and increased expression of plasminogen activator inhibitor-1 in the course of mice pneumosepsis.
Authors: Machado GB, de Oliveira AV, Saliba AM, de Lima CD, Suassuna JH, Plotkowski MC
Respir. Res., 2011-08-05;12(0):104.
Species: Mouse
Sample Types: BALF
-
Suppression of cytokine storm with a sphingosine analog provides protection against pathogenic influenza virus.
Authors: Walsh KB, Teijaro JR, Wilker PR
Proc. Natl. Acad. Sci. U.S.A., 2011-06-29;108(29):12018-23.
Species: Mouse
Sample Types: BALF
-
Lung-targeted overexpression of the NF-kappaB member RelB inhibits cigarette smoke-induced inflammation.
Authors: McMillan DH, Baglole CJ, Thatcher TH, Maggirwar S, Sime PJ, Phipps RP
Am. J. Pathol., 2011-05-05;179(1):125-33.
Species: Mouse
Sample Types: BALF
-
The encephalitogenicity of T(H)17 cells is dependent on IL-1- and IL-23-induced production of the cytokine GM-CSF.
Authors: El-Behi M, Ciric B, Dai H
Nat. Immunol., 2011-04-24;12(6):568-75.
Species: Mouse
Sample Types: Cell Culture Supernates
-
The Therapeutic Potential of the Humoral Pattern Recognition Molecule PTX3 in Chronic Lung Infection Caused by Pseudomonas aeruginosa.
Authors: Moalli F, Paroni M, Veliz Rodriguez T, Riva F, Polentarutti N, Bottazzi B, Valentino S, Mantero S, Nebuloni M, Mantovani A, Bragonzi A, Garlanda C
J. Immunol., 2011-03-25;186(9):5425-34.
Species: Mouse
Sample Types: Tissue Homogenates
-
CCL17 controls mast cells for the defense against filarial larval entry.
Authors: Specht S, Frank JK, Alferink J, Dubben B, Layland LE, Denece G, Bain O, Forster I, Kirschning CJ, Martin C, Hoerauf A
J. Immunol., 2011-03-11;186(8):4845-52.
Species: Mouse
Sample Types: Thoracic Cavity Fluid
-
CD4 T cells promote rather than control tuberculosis in the absence of PD-1-mediated inhibition.
Authors: Barber DL, Mayer-Barber KD, Feng CG
J. Immunol., 2010-12-20;186(3):1598-607.
Species: Mouse
Sample Types: BALF
-
A hypoxia- and alpha-fetoprotein-dependent oncolytic adenovirus exhibits specific killing of hepatocellular carcinomas.
Authors: Kwon OJ, Kim PH, Huyn S, Wu L, Kim M, Yun CO
Clin. Cancer Res., 2010-12-15;16(24):6071-82.
Species: Mouse
Sample Types: Serum
-
A novel mechanism of cytokine release in phagocytes induced by aggretin, a snake venom C-type lectin protein, through CLEC-2 ligation.
Authors: Chang CH, Chung CH, Hsu CC, Huang TY, Huang TF
J. Thromb. Haemost., 2010-11-01;8(11):2563-70.
Species: Mouse
Sample Types: Cell Culture Supernates
-
A critical role for C5L2 in the pathogenesis of experimental allergic asthma.
Authors: Zhang X, Schmudde I, Laumonnier Y, Pandey MK, Clark JR, Konig P, Gerard NP, Gerard C, Wills-Karp M, Kohl J
J. Immunol., 2010-10-25;185(11):6741-52.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Toll-like receptor 4 mediates the response of epithelial and stromal cells to lipopolysaccharide in the endometrium.
Authors: Sheldon IM, Roberts MH
PLoS ONE, 2010-09-22;5(9):e12906.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Importance of TLR2 in the direct response of T lymphocytes to Schistosoma mansoni antigens.
Authors: Burton OT, Gibbs S, Miller N, Jones FM, Wen L, Dunne DW, Cooke A, Zaccone P
Eur. J. Immunol., 2010-08-01;40(8):2221-9.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Distinct roles of hepatocyte- and myeloid cell-derived IL-1 receptor antagonist during endotoxemia and sterile inflammation in mice.
Authors: Lamacchia C, Palmer G, Bischoff L, Rodriguez E, Talabot-Ayer D, Gabay C
J. Immunol., 2010-07-16;185(0):2516-24.
Species: Mouse
Sample Types: Serum
-
Th17 cells are the dominant T cell subtype primed by Shigella flexneri mediating protective immunity.
Authors: Sellge G, Magalhaes JG, Konradt C, Fritz JH, Salgado-Pabon W, Eberl G, Bandeira A, Di Santo JP, Sansonetti PJ, Phalipon A
J. Immunol., 2010-01-20;184(4):2076-85.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Interleukin-15 contributes to the regulation of murine adipose tissue and human adipocytes.
Authors: Barra NG, Reid S, MacKenzie R
Obesity (Silver Spring), 2009-12-17;18(8):1601-7.
Species: Mouse
Sample Types: Serum
-
IL-1R1/MyD88 signaling is critical for elastase-induced lung inflammation and emphysema.
Authors: Couillin I, Vasseur V, Charron S, Gasse P, Tavernier M, Guillet J, Lagente V, Fick L, Jacobs M, Coelho FR, Moser R, Ryffel B
J. Immunol., 2009-12-15;183(12):8195-202.
Species: Mouse
Sample Types: BALF
-
Impact of adiponectin deficiency on pulmonary responses to acute ozone exposure in mice.
Authors: Zhu M, Hug C, Kasahara DI
Am. J. Respir. Cell Mol. Biol., 2009-11-13;43(4):487-97.
Species: Mouse
Sample Types: BALF
-
Nuclear factor-kappaB decoy oligodeoxynucleotides ameliorate impaired glucose tolerance and insulin resistance in mice with cecal ligation and puncture-induced sepsis.
Authors: Matsuda N, Yamamoto S, Yokoo H, Tobe K, Hattori Y
Crit. Care Med., 2009-10-01;37(10):2791-9.
Species: Mouse
Sample Types: Serum
-
E-prostanoid 3 receptor deletion improves pulmonary host defense and protects mice from death in severe Streptococcus pneumoniae infection.
Authors: Aronoff DM, Lewis C, Serezani CH, Eaton KA, Goel D, Phipps JC, Peters-Golden M, Mancuso P
J. Immunol., 2009-07-27;183(4):2642-9.
Species: Mouse
Sample Types: Tissue Homogenates
-
TREM-1 activation alters the dynamics of pulmonary IRAK-M expression in vivo and improves host defense during pneumococcal pneumonia.
Authors: Lagler H, Sharif O, Haslinger I, Matt U, Stich K, Furtner T, Doninger B, Schmid K, Gattringer R, de Vos AF, Knapp S
J. Immunol., 2009-07-13;183(3):2027-36.
Species: Mouse
Sample Types: Tissue Homogenates
-
Increased cytokine production in IL-18 receptor alpha-deficient cells is associated with dysregulation of suppressors of cytokine signaling (SOCS).
Authors: Nold-Petry CA, Nold MF, Nielsen JW, Bustamante A, Zepp JA, Storm KA, Hong JW, Kim SH, Dinarello CA
J. Biol. Chem., 2009-07-10;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
IL-6 is required for airway mucus production induced by inhaled fungal allergens.
Authors: Neveu WA, Allard JB, Dienz O, Wargo MJ, Ciliberto G, Whittaker LA, Rincon M
J. Immunol., 2009-07-10;183(3):1732-8.
Species: Mouse
Sample Types: BALF
-
Age-associated aggravation of clinical disease after primary metapneumovirus infection of BALB/c mice.
Authors: Darniot M, Pitoiset C, Petrella T, Aho S, Pothier P, Manoha C
J. Virol., 2009-01-14;83(7):3323-32.
Species: Mouse
Sample Types: BALF
-
Serotonin and angiotensin receptors in cardiac fibroblasts coregulate adrenergic-dependent cardiac hypertrophy.
Authors: Jaffre F, Bonnin P, Callebert J, Debbabi H, Setola V, Doly S, Monassier L, Mettauer B, Blaxall BC, Launay JM, Maroteaux L
Circ. Res., 2008-11-20;104(1):113-23.
Species: Mouse
Sample Types: Plasma
-
Modulation of macrophage infiltration and inflammatory activity by the phosphatase SHP-1 in virus-induced demyelinating disease.
Authors: Christophi GP, Hudson CA, Panos M, Gruber RC, Massa PT
J. Virol., 2008-11-05;83(2):522-39.
Species: Mouse
Sample Types: Tissue Homogenates
-
Identification of cardiac troponin I sequence motifs leading to heart failure by induction of myocardial inflammation and fibrosis.
Authors: Kaya Z, Goser S, Buss SJ, Leuschner F, Ottl R, Li J, Volkers M, Zittrich S, Pfitzer G, Rose NR, Katus HA
Circulation, 2008-10-27;118(20):2063-72.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Reduction in dietary omega-6 polyunsaturated fatty acids: eicosapentaenoic acid plus docosahexaenoic acid ratio minimizes atherosclerotic lesion formation and inflammatory response in the LDL receptor null mouse.
Authors: Wang S, Wu D, Matthan NR, Lamon-Fava S, Lecker JL, Lichtenstein AH
Atherosclerosis, 2008-09-02;204(1):147-55.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Methylprednisolone improves lung mechanics and reduces the inflammatory response in pulmonary but not in extrapulmonary mild acute lung injury in mice.
Authors: Leite-Junior JH, Garcia CS, Souza-Fernandes AB, Silva PL, Ornellas DS, Larangeira AP, Castro-Faria-Neto HC, Morales MM, Negri EM, Capelozzi VL, Zin WA, Pelosi P, Bozza PT, Rocco PR
Crit. Care Med., 2008-09-01;36(9):2621-8.
Species: Mouse
Sample Types: BALF
-
Adenosine receptors in regulation of dendritic cell differentiation and function.
Authors: Novitskiy SV, Ryzhov S, Zaynagetdinov R, Goldstein AE, Huang Y, Tikhomirov OY, Blackburn MR, Biaggioni I, Carbone DP, Feoktistov I, Dikov MM
Blood, 2008-06-17;112(5):1822-31.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Streptococcus equi antigens adsorbed onto surface modified poly-epsilon-caprolactone microspheres induce humoral and cellular specific immune responses.
Authors: Florindo HF, Pandit S, Goncalves LM, Alpar HO, Almeida AJ
Vaccine, 2008-06-17;26(33):4168-77.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Induction of IL-33 expression and activity in central nervous system glia.
Authors: Hudson CA, Christophi GP, Gruber RC, Wilmore JR, Lawrence DA, Massa PT
J. Leukoc. Biol., 2008-06-13;84(3):631-43.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Direct B cell stimulation by dendritic cells in a mouse model of lupus.
Authors: Wan S, Zhou Z, Duan B, Morel L
Arthritis Rheum., 2008-06-01;8(0):1741-50.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Administration of a synthetic TLR4 agonist protects mice from pneumonic tularemia.
Authors: Lembo A, Pelletier M, Iyer R, Timko M, Dudda JC, West TE, Wilson CB, Hajjar AM, Skerrett SJ
J. Immunol., 2008-06-01;180(11):7574-81.
Species: Mouse
Sample Types: Tissue Homogenates
-
Modulation of ozone-induced airway hyperresponsiveness and inflammation by interleukin-13.
Authors: Williams AS, Nath P, Leung SY, Khorasani N, McKenzie AN, Adcock IM, Chung KF
Eur. Respir. J., 2008-04-16;32(3):571-8.
Species: Mouse
Sample Types: BALF
-
Lack of Toll IL-1R8 exacerbates Th17 cell responses in fungal infection.
Authors: Bozza S, Zelante T, Moretti S, Bonifazi P, DeLuca A, D'Angelo C, Giovannini G, Garlanda C, Boon L, Bistoni F, Puccetti P, Mantovani A, Romani L
J. Immunol., 2008-03-15;180(6):4022-31.
Species: Mouse
Sample Types: Tissue Homogenates
-
VAMP-8 segregates mast cell-preformed mediator exocytosis from cytokine trafficking pathways.
Authors: Tiwari N, Wang CC, Brochetta C, Ke G, Vita F, Qi Z, Rivera J, Soranzo MR, Zabucchi G, Hong W, Blank U
Blood, 2008-01-18;111(7):3665-74.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Cigarette smoke-induced pulmonary inflammation is TLR4/MyD88 and IL-1R1/MyD88 signaling dependent.
Authors: Doz E, Noulin N, Boichot E, Guenon I, Fick L, Le Bert M, Lagente V, Ryffel B, Schnyder B, Quesniaux VF, Couillin I
J. Immunol., 2008-01-15;180(2):1169-78.
Species: Mouse
Sample Types: BALF
-
Gas6 promotes inflammation by enhancing interactions between endothelial cells, platelets, and leukocytes.
Authors: Tjwa M, Bellido-Martin L, Lin Y, Lutgens E, Plaisance S, Bono F, Delesque-Touchard N, Herve C, Moura R, Billiau AD, Aparicio C, Levi M, Daemen M, Dewerchin M, Lupu F, Arnout J, Herbert JM, Waer M, Garcia de Frutos P, Dahlback B, Carmeliet P, Hoylaerts MF, Moons L
Blood, 2007-12-21;111(8):4096-105.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Mycobacterium tuberculosis antigens specifically modulate CCR2 and MCP-1/CCL2 on lymphoid cells from human pulmonary hilar lymph nodes.
Authors: Arias MA, Jaramillo G, Lopez YP, Mejia N, Mejia C, Pantoja AE, Shattock RJ, Garcia LF, Griffin GE
J. Immunol., 2007-12-15;179(12):8381-91.
Species: Human
Sample Types: Cell Culture Supernates
-
Interleukin-1-induced interleukin-6 synthesis is mediated by the neutral sphingomyelinase/Src kinase pathway in neurones.
Authors: Tsakiri N, Kimber I, Rothwell NJ, Pinteaux E
Br. J. Pharmacol., 2007-12-03;153(4):775-83.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Deletion of TLR5 results in spontaneous colitis in mice.
Authors: Vijay-Kumar M, Sanders CJ, Taylor RT, Kumar A, Aitken JD, Sitaraman SV, Neish AS, Uematsu S, Akira S, Williams IR, Gewirtz AT
J. Clin. Invest., 2007-12-01;117(12):3909-21.
Species: Mouse
Sample Types: Serum
-
IL-1R1/MyD88 signaling and the inflammasome are essential in pulmonary inflammation and fibrosis in mice.
Authors: Gasse P, Mary C, Guenon I, Noulin N, Charron S, Schnyder-Candrian S, Schnyder B, Akira S, Quesniaux VF, Lagente V, Ryffel B, Couillin I
J. Clin. Invest., 2007-12-01;117(12):3786-99.
Species: Mouse
Sample Types: BALF
-
Caspase-1 contributes to Chlamydia trachomatis-induced upper urogenital tract inflammatory pathologies without affecting the course of infection.
Authors: Cheng W, Shivshankar P, Li Z, Chen L, Yeh IT, Zhong G
Infect. Immun., 2007-11-19;76(2):515-22.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Involvement of vitronectin in lipopolysaccaride-induced acute lung injury.
Authors: Tsuruta Y, Park YJ, Siegal GP, Liu G, Abraham E
J. Immunol., 2007-11-15;179(10):7079-86.
Species: Mouse
Sample Types: Tissue Homogenates
-
Transgenic blockade of interleukin 6 transsignaling abrogates inflammation.
Authors: Rabe B, Chalaris A, May U, Waetzig GH, Seegert D, Williams AS, Jones SA, Rose-John S, Scheller J
Blood, 2007-11-07;111(3):1021-8.
Species: Mouse
Sample Types: Air Pouch Exudate
-
The EGF receptor is required for efficient liver regeneration.
Authors: Natarajan A, Wagner B, Sibilia M
Proc. Natl. Acad. Sci. U.S.A., 2007-10-16;104(43):17081-6.
Species: Mouse
Sample Types: Serum, Tissue Homogenates
-
Mechanisms of interleukin-6 synthesis and release induced by interleukin-1 and cell depolarisation in neurones.
Authors: Tsakiri N, Kimber I, Rothwell NJ, Pinteaux E
Mol. Cell. Neurosci., 2007-09-11;37(1):110-8.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Differential ex vivo nitric oxide production by acutely isolated neonatal and adult microglia.
Authors: Schell JB, Crane CA, Smith MF, Roberts MR
J. Neuroimmunol., 2007-08-15;189(1):75-87.
Species: Mouse
Sample Types: Cell Culture Supernates
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Lactoferrin enhanced efficacy of the BCG vaccine to generate host protective responses against challenge with virulent Mycobacterium tuberculosis.
Authors: Hwang SA, Wilk KM, Budnicka M, Olsen M, Bangale YA, Hunter RL, Kruzel ML, Actor JK
Vaccine, 2007-07-27;25(37):6730-43.
Species: Mouse
Sample Types: Cell Culture Supernates
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Neurokinin-1 receptor antagonist treatment protects mice against lung injury in polymicrobial sepsis.
Authors: Hegde A, Zhang H, Moochhala SM, Bhatia M
J. Leukoc. Biol., 2007-06-12;82(3):678-85.
Species: Mouse
Sample Types: Plasma
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Nod1-mediated innate immune recognition of peptidoglycan contributes to the onset of adaptive immunity.
Authors: Fritz JH, Le Bourhis L, Sellge G, Magalhaes JG, Fsihi H, Kufer TA, Collins C, Viala J, Ferrero RL, Girardin SE, Philpott DJ
Immunity, 2007-04-12;26(4):445-59.
Species: Mouse
Sample Types: Cell Culture Supernates
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A synthetic analog of alpha-galactosylceramide induces macrophage activation via the TLR4-signaling pathways.
Authors: Hung LC, Lin CC, Hung SK, Wu BC, Jan MD, Liou SH, Fu SL
Biochem. Pharmacol., 2007-03-12;73(12):1957-70.
Species: Mouse
Sample Types: Cell Culture Supernates
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Role of Toll-like receptor 2 in recognition of Legionella pneumophila in a murine pneumonia model.
Authors: Fuse ET, Tateda K, Kikuchi Y, Matsumoto T, Gondaira F, Azuma A, Kudoh S, Standiford TJ, Yamaguchi K
J. Med. Microbiol., 2007-03-01;56(0):305-12.
Species: Mouse
Sample Types: Tissue Homogenates
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Differing effects of clarithromycin and azithromycin on cytokine production by murine dendritic cells.
Authors: Sugiyama K, Shirai R, Mukae H, Ishimoto H, Nagata T, Sakamoto N, Ishii H, Nakayama S, Yanagihara K, Mizuta Y, Kohno S
Clin. Exp. Immunol., 2007-03-01;147(3):540-6.
Species: Mouse
Sample Types: Cell Culture Supernates
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Glucose-6-phosphate dehydrogenase deficiency and the inflammatory response to endotoxin and polymicrobial sepsis.
Authors: Wilmanski J, Villanueva E, Deitch EA, Spolarics Z
Crit. Care Med., 2007-02-01;35(2):510-8.
Species: Mouse
Sample Types: Plasma
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Interleukin 10 regulates inflammatory cytokine synthesis to protect against lipopolysaccharide-induced abortion and fetal growth restriction in mice.
Authors: Robertson SA, Care AS, Skinner RJ
Biol. Reprod., 2007-01-10;76(5):738-48.
Species: Mouse
Sample Types: Serum
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A functional comparison of canine and murine bone marrow derived cultured mast cells.
Authors: Lin TY, London CA
Vet. Immunol. Immunopathol., 2006-10-06;114(3):320-34.
Species: Mouse
Sample Types: Cell Culture Supernates
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Essential role for IL-10 in resistance to lipopolysaccharide-induced preterm labor in mice.
Authors: Robertson SA, Skinner RJ, Care AS
J. Immunol., 2006-10-01;177(7):4888-96.
Species: Mouse
Sample Types: Serum
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Effects of dexamethasone on macrophage migration inhibitory factor production in sepsis.
Authors: Bruhn A, Verdant C, Vercruysse V, Su F, Vray B, Vincent JL
Shock, 2006-08-01;26(2):169-73.
Species: Mouse
Sample Types: Plasma
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Exogenous platelet-activating factor acetylhydrolase reduces mortality in mice with systemic inflammatory response syndrome and sepsis.
Authors: Gomes RN, Bozza FA, Amancio RT, Japiassu AM, Vianna RC, Larangeira AP, Gouvea JM, Bastos MS, Zimmerman GA, Stafforini DM, Prescott SM, Bozza PT, Castro-Faria-Neto HC
Shock, 2006-07-01;26(1):41-9.
Species: Mouse
Sample Types: Peritoneal Fluid
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Effects of dexamethazone on LPS-induced activationand migration of mouse dendritic cells revealed by a genome-wide transcriptional analysis.
Authors: Vizzardelli C, Pavelka N, Luchini A, Zanoni I, Bendickson L, Pelizzola M, Beretta O, Foti M, Granucci F, Nilsen-Hamilton M, Ricciardi-Castagnoli P
Eur. J. Immunol., 2006-06-01;36(6):1504-15.
Species: Mouse
Sample Types: Cell Culture Supernates
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Choosing the frequency of deep inflation in mice: balancing recruitment against ventilator-induced lung injury.
Authors: Allen GB, Suratt BT, Rinaldi L, Petty JM, Bates JH
Am. J. Physiol. Lung Cell Mol. Physiol., 2006-05-12;291(4):L710-7.
Species: Mouse
Sample Types: BALF
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The effects of dehydroepiandrosterone (DHEA) on in vitro spleen cell proliferation and cytokine production.
Authors: Powell JM, Sonnenfeld G
J. Interferon Cytokine Res., 2006-01-01;26(1):34-9.
Species: Mouse
Sample Types: Cell Culture Supernates
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Increased pulmonary responses to acute ozone exposure in obese db/db mice.
Authors: Lu FL, Johnston RA, Flynt L, Theman TA, Terry RD, Schwartzman IN, Lee A, Shore SA
Am. J. Physiol. Lung Cell Mol. Physiol., 2005-12-22;290(5):L856-65.
Species: Mouse
Sample Types: Serum
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MyD88-dependent and -independent murine cytomegalovirus sensing for IFN-alpha release and initiation of immune responses in vivo.
Authors: Delale T, Paquin A, Asselin-Paturel C, Dalod M, Brizard G, Bates EE, Kastner P, Chan S, Akira S, Vicari A, Biron CA, Trinchieri G, Briere F
J. Immunol., 2005-11-15;175(10):6723-32.
Species: Mouse
Sample Types: Serum
-
Anti-inflammatory activity in the aqueous crude extract of the leaves of Nidularium procerum: A bromeliaceae from the Brazilian coastal rain forest.
Authors: Amendoeira FC, Frutuoso VS, Zanon C, Chedier LM, Figueiredo MR, Kaplan MA, Bandeira-Melo C, Bozza PT, Castro-Faria-Neto HC
Biol. Pharm. Bull., 2005-06-01;28(6):1010-5.
Species: Mouse
Sample Types: Pleural Fluid
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Pyocyanin production by Pseudomonas aeruginosa induces neutrophil apoptosis and impairs neutrophil-mediated host defenses in vivo.
Authors: Allen L, Dockrell DH, Pattery T, Lee DG, Cornelis P, Hellewell PG, Whyte MK
J. Immunol., 2005-03-15;174(6):3643-9.
Species: Mouse
Sample Types: BALF
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Comparative immunomodulatory properties of a chitosan-MDP adjuvant combination following intranasal or intramuscular immunisation.
Authors: Moschos SA, Bramwell VW, Somavarapu S, Alpar HO
Vaccine, 2005-03-14;23(16):1923-30.
Species: Mouse
Sample Types: Cell Culture Supernates
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Fatal Mycobacterium tuberculosis infection despite adaptive immune response in the absence of MyD88.
Authors: Fremond CM, Yeremeev V, Nicolle DM, Jacobs M, Quesniaux VF, Ryffel B
J. Clin. Invest., 2004-12-01;114(12):1790-9.
Species: Mouse
Sample Types: Cell Culture Supernates
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Active hexose correlated compound enhances the immune function of mice in the hindlimb-unloading model of spaceflight conditions.
Authors: Aviles H, Belay T, Vance M, Sun B, Sonnenfeld G
J. Appl. Physiol., 2004-06-11;97(4):1437-44.
Species: Mouse
Sample Types: Cell Culture Supernates
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Cytokine production in association with phagocytosis of apoptotic cells by immature dendritic cells.
Authors: Takahashi M, Kobayashi Y
Cell. Immunol., 2003-12-01;226(2):105-15.
Species: Mouse
Sample Types: Cell Culture Supernates
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Adenoviral infection decreases mortality from lipopolysaccharide-induced liver failure via induction of TNF-alpha tolerance.
Authors: Yarovinsky TO, Powers LS, Butler NS, Bradford MA, Monick MM, Hunninghake GW
J. Immunol., 2003-09-01;171(5):2453-60.
Species: Mouse
Sample Types: Serum
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Average Rating: 4.8 (Based on 43 Reviews)
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IL6 calibration curve. Excellent performance, easy to use.
Used this kit for quantifying mouse IL-6 in serum samples, could see the detection but not strong in our samples. Standard curve looks good.
RAW Cells cultured with 10ng/mL LPS for 24hrs
Mouse IL-6 was evaluated in intestinal tissues from C57BL/6J mice treated with Dextran sodium sulfate (DSS) as chemical pro-inflammatory drug aiming to simulate chronic colitis (DSS: 2.5%, 7 days treatment). Results were consistent to what was expected from this assay, and were in agreement with previous reports for this mouse strain. Treatments correspond to Moringa oleifera powder administered to mice (20 and 50% of total caloric content).
Excellent kit. Easy to use, clear instructions, performs perfectly and consistently.
We used this DuoSet for looking at IL-6 within the supernatant of C2C12 myotubes stimulated with various ligands. We were able to run the samples neat and received great results.
Excellent performance
Reliable results and easy to follow protocol
consistent results, easy to use
50ul of murine IL-6 Capture antibody (2ug/mL) was coated per well of a 96 well plate at 4 degrees overnight. Purified mIL-6 standard was diluted (7 fold) and assayed to ensure the quality of the ELISA. Mouse IL-6 Detector antibody was added (2h @ RT) followed by a 20 min incubation with Streptavidin-HRP. Substrate solution was added to measure mIL-6 concentration according to the manufactures protocol. The standard curve looked great as can be seen by calculation of the R- squared value. Highly recommend doing ELISA's using kits from R&D.
Buffer: 7-Fold dilution cruve was tried (only values that genrated a linear curve are shown)