Gene engineering is a key step in generating immune cell and regenerative medicine therapies. This process alters the genome of a cell either by making precise edits or introducing new genetic material. Cell engineering can augment cell therapy effectiveness by increasing cell potency and persistence in vivo. It has recently been used to generate CAR-T and CAR-NK cells, suppress immune responses in autoimmune diseases and chronic inflammation, mask cell therapies to avoid host immunity, enable cells to infiltrate target tissues, and deliver genes or correct genetic defects for gene therapy.
Download this guide to learn about:
- Non-viral gene engineering with the TcBuster™ transposon system
- How TcBuster compares with virus-based systems for cell therapy manufacturing
- Optimization of the TcBuster platform for different research areas and manufacturing scales
- Additional products and services for cell therapy manufacturing
- Automated analytical solutions for cell and gene therapy research
