1-Deoxymannojirimycin hydrochloride

Name: 1-Deoxymannojirimycin hydrochloride
Brand: Tocris Bioscience
SKU: 1259
Price: 183 USD

Catalog #: 1259
1 Citation Datasheet / COA / SDS

Discontinued Product

1259 has been discontinued.

View all Glycosylase Inhibitors products.

1-Deoxymannojirimycin hydrochloride | CAS No. 73465-43-7 | Glycosylase Inhibitors

1 Image

Description: α-Mannosidase I inhibitor

Chemical Name: (2R,3R,4R,5R)-2-(Hydroxymethyl)-3,4,5-piperidinetriol hydrochloride

View All Products for Glycosylase Inhibitors

Product Details

Citations (1)

Reviews

Biological Activity Technical Data Background Product Datasheets Calculators

Biological Activity

1-Deoxymannojirimycin hydrochloride is a selective inhibitor of α-mannosidase I.

Technical Data

M.Wt:

199.63

Formula:

C₆H₁₃NO₄.HCl

Solubility:

Soluble to 50 mM in water

Storage:

Desiccate at RT

CAS No:

73465-43-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death.
Fox JT, Sakamuru S, Huang R
Proc. Natl. Acad. Sci. U.S.A., 2012;109(14):5423-8.
Identification and functional characterization of a highly divergent N-acetylglucosaminyltransferase I (TbGnTI) in Trypanosoma brucei.
Damerow M, Rodrigues J, Wu D, Guther M, Mehlert A, Ferguson M
J Biol Chem, 2014;289(13):9328-39.
The use of 1-deoxymannojirimycin to evaluate the role of various α-mannosidases in oligosaccharide processing in intact cells.
Bischoff et al.
J.Biol.Chem., 1986;261:4766
The effect of 1-deoxymannojirimycin on rat liver α-mannosidases.
Bischoff and Kornfeld
Biochem.Biophys.Res.Commun., 1984;125:324
Novel mannosidase inhibitor blocking conversion of high mannose to complex oligosaccharides.
Fuhrmann et al.
Nature, 1984;307:755

Product Datasheets

COA view current batch

Or select another batch:

View Batch

SDS

Reconstitution Calculator

Molarity Calculator

Citation for 1-Deoxymannojirimycin hydrochloride

The citations listed below are publications that use Tocris products. Selected citations for 1-Deoxymannojirimycin hydrochloride include:

1 Citation: Showing 1 - 1

Design of a novel integration-deficient lentivector technology that incorporates genetic and posttranslational elements to target human dendritic cells.
Authors: Tareen Et al.
Mol Ther 2014;22:575

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Reviews for 1-Deoxymannojirimycin hydrochloride

There are currently no reviews for this product. Be the first to review 1-Deoxymannojirimycin hydrochloride and earn rewards!

Have you used 1-Deoxymannojirimycin hydrochloride?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review

Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.