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3,5-DHBA

Catalog #: 4599
1 Citation Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
4599/50
3,5-DHBA | CAS No. 99-10-5 | Orphan 7-TM Receptor Agonists
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Description: Selective HCA1 agonist

Chemical Name: 3,5-Dihydroxybenzoic acid

Purity: ≥99%

Product Details
Citations (1)
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Biological Activity

3,5-DHBA is a selective agonist of hydroxycarboxylic acid receptor 1 (HCA1, also known as GPR81) (EC50 ~150 μM). Inhibits lipolysis in wild-type mouse adipocytes. Displays minimal activity at HCA2 (at concentrations >10 mM) and no activity at HCA3, free fatty acid receptor (FFAR) 2 or FFAR3.

Technical Data

M.Wt:
154.12
Formula:
C7H6O4
Solubility:
Soluble to 100 mM in water and to 100 mM in DMSO
Purity:
≥99%
Storage:
Store at RT
CAS No:
99-10-5

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Citation for 3,5-DHBA

The citations listed below are publications that use Tocris products. Selected citations for 3,5-DHBA include:

1 Citation: Showing 1 - 1

  1. Hydrocarboxylic acid receptor 1 in BAT regulates glucose uptake in mice fed a high-fat diet.
    Authors: Taesik Et al.
    PLoS One  2020;15:e0228320

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