5-Iodo-A-85380, 5-trimethylstannyl N-BOC derivative
Discontinued Product
Chemical Name: (2S)-2-[[[5-(Trimethylstannyl)-3-pyridinyl]oxy]methyl]-1-azetidinecarboxylic acid, t-butyl ester
Purity: ≥98%
Biological Activity
5-Iodo-A-85380, 5-trimethylstannyl N-BOC derivative is a precursor to the highly potent and selective ligand for the α4β2 nicotinic receptor, 5-Iodo-A-85380 (Cat. No.1518). Suitable for radioiodination.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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2-, 5-, and 6-Halo-3-(2(S)-azetidinylmethoxy)pyridines: synthesis, affinity for nicotinic acetylcholine receptors, and molecular modeling.
Koren et al.
J.Med.Chem., 1998;41:3690 -
5-Iodo-A-85380, an α4β2 subtype-selective ligand for nicotinic acetylcholine receptors.
Mukhin et al.
Mol.Pharmacol., 2000;57:642
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