(±)-5'-Chloro-5'-deoxy-ENBA

Catalog #: 3576
2 Citations Datasheet / COA / SDS

Catalog #	Availability	Size / Price	Qty
3576/10
3576/50

(±)-5'-Chloro-5'-deoxy-ENBA | CAS No. 103626-26-2 | Adenosine A1 Receptor Agonists

1 Image

Description: Highly selective A1 agonist

Chemical Name: N-Bicyclo[2.2.1]hept-2-yl-5'-chloro-5'-deoxyadenosine

Purity: ≥98%

View All Products for Adenosine A1 Receptor Agonists

Product Details

Citations (2)

Supplemental Products

Reviews

Biological Activity Technical Data Background Product Datasheets Calculators

Biological Activity

(±)-5'-Chloro-5'-deoxy-ENBA is a highly selective adenosine A₁ receptor agonist (K_i values are 0.51, 1290, 1340 and 2740 nM at A₁, A₃, A_2A and A_2B receptors respectively). Reverses formalin-induced nocifensive behavior in mice; antinociceptive.

Technical Data

M.Wt:

379.84

Formula:

C₁₇H₂₂ClN₅O₃

Solubility:

Soluble to 100 mM in DMSO and to 100 mM in ethanol

Purity:

≥98%

Storage:

Store at -20°C

CAS No:

103626-26-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

N⁶-bicycloalkyladenosines with unusually high potency and selectivity for the adenosine A1 receptor.
Trivedi et al.
J.Med.Chem., 1989;32:8
N⁶-cycloalkyl- and N⁶-bicycloalkyl-C5'(C2')-modified adenosine derivatives as high-affinity and selective agonists at the human A₁ adenosine receptor with antinociceptive effects in mice.
Franchetti et al.
J.Med.Chem., 2009;52:2393

Product Datasheets

COA view current batch

Or select another batch:

View Batch

SDS

Reconstitution Calculator

Molarity Calculator

Reconstitution Calculator

Molarity Calculator

Mass

Concentration

Volume

M. Wt* g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Citations for (±)-5'-Chloro-5'-deoxy-ENBA

The citations listed below are publications that use Tocris products. Selected citations for (±)-5'-Chloro-5'-deoxy-ENBA include:

2 Citations: Showing 1 - 2

Adenosine A2A Receptor Activation Enhances Blood-Tumor Barrier Permeability in a Rodent Glioma Model.
Authors: Wei Et al.
Mol Cancer Res 2021;19:2081-2095
Activation of neuronal adenosine A1 receptors causes hypothermia through central and peripheral mechanisms.
Authors: Cuiying Et al.
PLoS One 2020;15:e0243986

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Reviews for (±)-5'-Chloro-5'-deoxy-ENBA

There are currently no reviews for this product. Be the first to review (±)-5'-Chloro-5'-deoxy-ENBA and earn rewards!

Have you used (±)-5'-Chloro-5'-deoxy-ENBA?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review

Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.