ABP 688

Catalog #: 5229 Datasheet / COA / SDS

Catalog #	Availability	Size / Price	Qty
5229/50
5229/10

ABP 688 | CAS No. 924298-51-1 | Group I mGluR Antagonists

1 Image

Description: High affinity human mGlu5 antagonist

Chemical Name: 3-[2-(6-Methyl-2-pyridinyl)ethynyl]-2-cyclohexene-1-one O-methyloxime

Purity: ≥98%

View All Products for Group I mGluR Antagonists

Product Details

Supplemental Products

Reviews

Biological Activity Technical Data Background Product Datasheets Calculators

Biological Activity

ABP 688 is a high affinity human mGlu₅ receptor antagonist (K_i = 1.7 nM). Inhibits glutamate-induced calcium release from L(tk-) cells expressing human mGlu₅ receptors (IC₅₀ = 2.3 nM).

Technical Data

M.Wt:

240.3

Formula:

C₁₅H₁₆N₂O

Solubility:

Soluble to 100 mM in DMSO and to 50 mM in 1eq. HCl

Purity:

≥98%

Storage:

Store at -20°C

CAS No:

924298-51-1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

ABP688, a novel selective and high affinity ligand for the labeling of mGlu₅ receptors: identification, in vitro pharmacology, pharmacokinetic and biodistribution studies.
Hintermann et al.
Bioorg.Med.Chem., 2007;15:903

Product Datasheets

COA view current batch

SDS

Reconstitution Calculator

Molarity Calculator

Reconstitution Calculator

Molarity Calculator

Mass

Concentration

Volume

M. Wt* g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Reviews for ABP 688

There are currently no reviews for this product. Be the first to review ABP 688 and earn rewards!

Have you used ABP 688?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review

Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.