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Ac4ManNDAz

Catalog #: 7553 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
7553/10
Ac4ManNDAz | CAS No. 1015698-39-1 | Photoactivatable Cross-linking Probes
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Description: Photo-crosslinking probe for studying glycoproteins and glycolipids

Chemical Name: 2-Deoxy-2-[[3-(3-methyl-3H-diazirin-3-yl)-1-oxopropyl]amino]-D-mannopyranose-1,3,4,6-tetraacetate

Purity: ≥98%

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Biological Activity

Ac4ManNDAz is a cell-permeable photo-crosslinking probe for studying glycoprotein or glycolipid interactions. The compound is an unnatural diazirine-containing monosaccharide building block, which acts as a photo-crosslinker. Once inside the cell, Ac4ManNDAz is metabolized and incorporated into cell surface glycoproteins as a photo-crosslinking sialic acid analog. Upon UV irradiation, the diazirine group is activated to a reactive carbene that covalently crosslinks to nearby molecules.

Technical Data

M.Wt:
457.44
Formula:
C19H27N3O10
Solubility:
Soluble to 100 mM in ethanol and to 100 mM in DMSO
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
1015698-39-1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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