ARCC 4 negative control

Catalog #: 7255 Datasheet / COA / SDS

Catalog #	Availability	Size / Price	Qty
7255/5

ARCC 4 negative control | CAS No. 2156588-26-8 | Active Degrader Negative Controls

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Description: Negative control for ARCC 4 (Cat. No. 7254)

Chemical Name: (2S,4S)-1-((S)-2-(2-(4-((4'-(3-(4-Cyano-3-(trifluoromethyl)phenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl)-[1,1'-biphenyl]-4-yl)oxy)butoxy)acetamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide

Purity: ≥98%

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Biological Activity

ARCC 4 negative control is a negative control for ARCC 4 (Cat. No. 7254). Binds androgen receptors (AR) without inducing degradation.

Technical Data

M.Wt:

1024.18

Formula:

C₅₃H₅₆F₃N₇O₇S₂

Solubility:

Soluble to 100 mM in DMSO

Purity:

≥98%

Storage:

Store at -20°C

CAS No:

2156588-26-8

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

Androgen receptor degradation by the proteolysis-targeting chimera ARCC-4 outperforms enzalutamide in cellular models of prostate cancer drug resistance.
Salami et al.
Commun.Biol., 2018;1:100

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