[Arg8]-Vasopressin
Purity: ≥95%
Biological Activity
[Arg8]-Vasopressin is an antidiuretic hormone found in most mammalian species. Also acts as a neurotransmitter at synapses in the brain; increases [Ca2+]i in cultured rat hippocampal neurons.Technical Data
(Modifications: Disulfide bridge: 1-6, Gly-9 = C-terminal amide)
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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Nutritional state-dependent ghrelin activation of vasopressin neurons via retrograde trans-neuronal-glial stimulation of excitatory GABA circuits.
Haam J, Halmos K, Di S, Tasker J
J Neurosci, 2014;34(18):6201-13. -
Bidirectional control of mRNA translation and synaptic plasticity by the cytoplasmic polyadenylation complex.
Udagawa T, Swanger S, Takeuchi K, Kim J, Nalavadi V, Shin J, Lorenz L, Zukin R, Bassell G, Richter J
Mol Cell, 2012;47(2):253-66. -
[Arg8]-vasopressin-induced increase in intracellular Ca2+ concentration in cultutred rat hippocampal neurons.
Migara et al.
Brain Res.Bull., 1999;49:343 -
Control of renal medulaary circulation by vasopressin V1 and V2 receptors in the rat.
Cowley et al.
Exp.Physiol., 2000;85S:223S -
Discovery and design of novel and selective vasopressin and oxyt. agonists and antagonists: the role of bioassays.
Chan et al.
Exp.Physiol., 2000;85S:7S
Product Datasheets
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Citations for [Arg8]-Vasopressin
The citations listed below are publications that use Tocris products. Selected citations for [Arg8]-Vasopressin include:
2 Citations: Showing 1 - 2
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A circuit from hippocampal CA2 to lateral septum disinhibits social aggression.
Authors: Leroy Et al.
Nature 2018;564:213
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The orphan G protein-coupled receptor GPR139 is activated by the peptides: Adrenocorticotropic hormone (ACTH), α-, and β-melanocyte stimulating hormone (α-MSH, and β-MSH), and the conserved core motif HFRW.
Authors: Nøhr Et al.
Neurochem Int 2017;102:105
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