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ARN 11391

Catalog #: 7909 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
7909/10
7909/50
ARN 11391 | CAS No. 1214569-31-9 | IP3R1
1 Image
Description: Potentiator of the IP3-gated calcium channel ITPR1

Chemical Name: 2-Ethyl-4,5,6,7-tetrahydro-N-[2-[(tetrahydro-2H-pyran-2-yl)methoxy]phenyl]-2H-indazole-3-carboxamide

Purity: ≥98%

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Biological Activity

ARN 11391 is a potentiator of the IP3-gated calcium channel ITPR1 (Inositol 1,4,5-trisphosphate (IP3) receptor type 1). It amplifies intracellular calcium ion signaling by acting directly on ITPR1. ARN 11391 also potentiates calcium signaling in cells expressing mutant ITPR1 which is associated with SCA29, a form of spinocerebellar ataxia.

Technical Data

M.Wt:
383.49
Formula:
C22H29N3O3
Solubility:
Soluble to 100 mM in DMSO and to 100 mM in ethanol
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
1214569-31-9

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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