Autocamtide-2-related inhibitory peptide
Purity: ≥95%
Biological Activity
Autocamtide-2-related inhibitory peptide is a selective and potent calmodulin-dependent protein kinase II (CaM kinase II) inhibitor (IC50 = 40 nM). Selective over PKC, PKA and CaM kinase IV (IC50 > 10 μM).Cell permeable derivative also available.
Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Additional Information
Background References
-
The serine/threonine kinase Ndr2 controls integrin trafficking and integrin-dependent neurite growth.
Rehberg K, Kliche S, Madencioglu D, Thiere M, Muller B, Meineke B, Freund C, Budinger E, Stork O
J Neurosci, 2014;34(15):5342-54. -
A novel highly specific and potent inhibitor of calmodulin-dependent protein kinase II.
Ishida et al.
Biochem.Biophys.Res.Commun., 1995;212:806 -
Stabilization of calmodulin-dependent protein kinase II through the autoinhibitory domain.
Ishida and Fujisawa
J.Biol.Chem., 1995;270:2163 -
Requirement of calmodulin-dependent protein kinase II in cyclic ADP-ribose-mediated intracellular Ca2+ mobilization.
Takasawa et al.
J.Biol.Chem., 1995;270:30257
Product Datasheets
Reconstitution Calculator
Molarity Calculator
Citations for Autocamtide-2-related inhibitory peptide
The citations listed below are publications that use Tocris products. Selected citations for Autocamtide-2-related inhibitory peptide include:
2 Citations: Showing 1 - 2
-
Pituitary adenylate cyclase-activating polypeptide induces postsynaptically expressed potentiation in the intra-amygdala circuit.
Authors: Cho Et al.
J Neurosci 2012;32:14165
-
Co-induction of LTP and LTD and its regulation by protein kinases and phosphatases.
Authors: Grey and Burrell
J Neurophysiol 2010;103:2737
FAQs
No product specific FAQs exist for this product, however you may
View all Peptide FAQsReviews for Autocamtide-2-related inhibitory peptide
There are currently no reviews for this product. Be the first to review Autocamtide-2-related inhibitory peptide and earn rewards!
Have you used Autocamtide-2-related inhibitory peptide?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image