[bAla8]-Neurokinin A(4-10)
![[bAla8]-Neurokinin A(4-10)](https://resources.rndsystems.com/images/datasheets/structures/bala8-neurokinin-a4-10_1640.png "[bAla8]-Neurokinin A(4-10)")
Biological Activity
[bAla8]-Neurokinin A(4-10) is a NK2 receptor agonist (pD2 = 6.91). Produces bladder contraction and bronchospasm in guinea pigs in vivo.Technical Data
(Modifications: Ala-5 = β-Ala, Met-7 = C-terminal amide)
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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Tachykinin NK2 receptors and enhancement of cholinergic transmission in the inflamed rat colon: an in vivo motility study.
Carini et al.
Br.J.Pharmacol., 2001;133:1107 -
In vivo pharmacology of [βAla8]neurokinin A-(4-10), a selective NK-2 tachykinin receptor agonist.
Maggi et al.
Eur.J.Pharmacol., 1990;177:81 -
A potent and selective agonist for NK-2 tachykinin receptor.
Rovero et al.
Peptides, 1989;10:593
Product Datasheets
Citation for [bAla8]-Neurokinin A(4-10)
The citations listed below are publications that use Tocris products. Selected citations for [bAla8]-Neurokinin A(4-10) include:
1 Citation: Showing 1 - 1
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Regulation of substrate utilization and adiposity by Agrp neurons.
Authors: Cavalcanti-de-Albuquerque Et al.
Nat Commun 2019;10:311
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