Benzbromarone
Discontinued Product
Chemical Name: (3,5-Dibromo-4-hydroxyphenyl)(2-ethyl-3-benzofuranyl)methanone
Purity: ≥99%
Biological Activity
TMEM16A/B calcium-activated chloride channel (CaCC) blocker. Inhibits ATP-induced mucin secretion and metacholine-induced airway smooth muscle contraction in vitro.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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Calcium-activated chloride channel TMEM16A modulates mucin secretion and airway smooth muscle contraction.
Huang et al.
Proc.Natl.Acad.Sci.U.S.A., 2012;109:16354 -
Functional expression of the TMEM16 family of calcium-activated chloride channels in airway smooth muscle.
Gallos et al.
Am.J.Physiol.Lung Cell Mol.Physiol., 2013;305:625
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