Bioymifi

Catalog #: 5372 Datasheet / COA / SDS

Discontinued Product

5372 has been discontinued.
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Bioymifi | CAS No. 1420071-30-2 | Cytokine Compounds
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Description: DR5 (TRAIL receptor) agonist; induces apoptosis

Chemical Name: 5-[5-[[(5Z)-3-(4-Bromophenyl)-2-imino-4-oxo-5-thiazolidinylidene]methyl]-2-furanyl]-1H-isoindole-1,3(2H)-dione

Purity: ≥97%

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Biological Activity

Bioymifi is a DR5 (TRAIL receptor) agonist. Directly binds extracellular domain of DR5 (Kd = 1.2 μM) and induces the formation of DR5 aggregates. Induces apoptosis of glioblastoma cells.

Technical Data

M.Wt:
494.32
Formula:
C22H12BrN3O4S
Solubility:
Soluble to 1 mM in DMSO with gentle warming
Purity:
≥97%
Storage:
Store at +4°C
CAS No:
1420071-30-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Small-molecule activation of the TRAIL receptor DR5 in human cancer cells.
    Wang et al.
    Nat.Chem.Biol., 2013;9:84

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