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C-type natriuretic peptide (1-22) (human, rat, swine)

Catalog #: 3520
4 Citations Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
3520/500U
C-type natriuretic peptide (1-22) (human, rat, swine)
1 Image
Description: Endogenous peptide agonist at NPR2

Purity: ≥95%

Product Details
Citations (4)
Reviews
Biological Activity Technical Data Background Product Datasheets Calculators

Biological Activity

C-type natriuretic peptide (1-22) (human, rat, swine) is an endogenous peptide found in plasma and cerebrospinal fluid. Behaves as an agonist at natriuretic peptide receptor NPR2 (NPRB) and exhibits affinity for NPR3 (NPRC). Inhibits L-type calcium currents in myocytes and exhibits antiproliferative effects in cardiac fibroblasts in vitro. Regulates cartilage homeostasis, body fluid volume and exhibits vasodilatory activity in vivo.

Technical Data

M.Wt:
2197.61
Formula:
C93H157N27O28S3
Sequence:
GLSKGCFGLKLDRIGSMSGLGC

(Modifications: Disulfide bridge: 6-22)

Solubility:
Soluble to 1 mg/ml in water
Purity:
≥95%
Storage:
Store at -20°C
CAS No:
127869-51-6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Citations for C-type natriuretic peptide (1-22) (human, rat, swine)

The citations listed below are publications that use Tocris products. Selected citations for C-type natriuretic peptide (1-22) (human, rat, swine) include:

4 Citations: Showing 1 - 4

  1. 3D doppler ultrasound imaging of cerebral blood flow for assessment of neonatal hypoxic-ischemic brain injury in mice.
    Authors: Lubo Et al.
    PLoS One  2023;18:e0285434
  2. Coordinated Formation of IMPDH2 Cytoophidium in Mouse Oocytes and Granulosa Cells.
    Authors: Hui Et al.
    Front Cell Dev Biol  2021;9:690536
  3. C-Type Natriuretic Peptide Ameliorates Vascular Injury and Improves Neurological Outcomes in Neonatal Hypoxic-Ischemic Brain Injury in Mice.
    Authors: Zhen Et al.
    Int J Mol Sci  2021;22
  4. Contribution of Kv7 channels to natriuretic peptide mediated vasodilation in normal and hypertensive rats.
    Authors: Stott Et al.
    Hypertension  2015;65:676

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