Caspase-3 Colorimetric Assay Kit

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K106-100 has been discontinued.
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Citations (97)
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Caspase-3 Colorimetric Assay Kit Summary

Specifications

Source
N/A
Shipping Conditions
The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Species
Multi-Species

Product Datasheets

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Background: Caspase-3

Caspases are a family of cytosolic aspartate-specific cysteine proteases involved in the initiation and execution of apoptosis. They are expressed as latent zymogens and are activated by an autoproteolytic mechanism or by processing by other proteases (frequently other caspases). Human caspases can be subdivided into three functional groups: cytokine activation (caspase-1, -4, -5, and -13), apoptosis initiation (caspase-2, -8, -9, -and -10), and apoptosis execution (caspase-3, -6, and -7).

Caspases are regulated by a variety of stimili, including APAF1, CFLAR/FLIP, NOL3/ARC, and members of the inhibitor of apoptosis (IAP) family such as BIRC1/NAIP, BIRC2/cIAP-1, BIRC3/cIAP-2, BIRC4/XIAP, BIRC5/Survivin, and BIRC7/Livin. IAP activity is modulated by DIABLO/SMAC or PRSS25/HTRA2/Omi. Cell-permeable and irreversible peptide inhibitors are also available for different caspases.

Entrez Gene IDs
836 (Human); 12367 (Mouse)
Alternate Names
Apopain; apoptosis-related cysteine protease; CASP3; CASP-3; caspase 3, apoptosis-related cysteine peptidase; Caspase3; Caspase-3; CPP32; CPP-32; CPP32B; CPP32SREBP cleavage activity 1; Cysteine protease CPP32; EC 3.4.22; EC 3.4.22.56; LICE-1; PARP cleavage protease; procaspase3; Protein Yama; SCA-1; YAMA

Citations for Caspase-3 Colorimetric Assay Kit

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

97 Citations: Showing 1 - 10
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  1. Azadirachtin Attenuates Lipopolysaccharide-Induced ROS Production, DNA Damage, and Apoptosis by Regulating JNK/Akt and AMPK/mTOR-Dependent Pathways in Rin-5F Pancreatic Beta Cells
    Authors: A John, H Raza
    Biomedicines, 2021-12-18;9(12):.  2021-12-18
  2. Apigenin Induces Autophagy and Cell Death by Targeting EZH2 under Hypoxia Conditions in Gastric Cancer Cells
    Authors: TW Kim, HG Lee
    International Journal of Molecular Sciences, 2021-12-15;22(24):.  2021-12-15
  3. Xeno-free workflow exhibits comparable efficiency and quality of keratinocytes isolated from human skin biopsies
    Authors: C Lagerwall, H Shahin, S Abdallah, I Steinvall, M Elmasry, F Sjöberg, AT El-Serafi
    Regenerative Therapy, 2021-09-29;18(0):401-407.  2021-09-29
  4. NPAS4 suppresses propofol-induced neurotoxicity by inhibiting autophagy in hippocampal neuronal cells
    Authors: T Zhang, D Ji, J Sun, J Song, L Nie, N Sun
    Archives of biochemistry and biophysics, 2021-08-18;711(0):109018.  2021-08-18
  5. Physiological responses (Hsps 60 and 32, caspase 3, H2O2 scavenging, and photosynthetic activity) of the coral Pocillopora damicornis under thermal and high nitrate stresses
    Authors: M Thummasan, BE Casareto, C Ramphul, T Suzuki, K Toyoda, Y Suzuki
    Marine pollution bulletin, 2021-07-20;171(0):112737.  2021-07-20
  6. Surfactin exerts an anti-cancer effect through inducing allergic reactions in melanoma skin cancer
    Authors: HY Kim, H Jung, HM Kim, HJ Jeong
    International immunopharmacology, 2021-07-04;99(0):107934.  2021-07-04
  7. Nitrofurazone repurposing towards design and synthesis of novel apoptotic-dependent anticancer and antimicrobial agents: Biological evaluation, kinetic studies and molecular modeling
    Authors: MH El-Wakil, MA Meheissen, MM Abu-Serie
    Bioorganic chemistry, 2021-05-07;113(0):104971.  2021-05-07
  8. 8-Alkylmercaptocaffeine derivatives: antioxidant, molecular docking, and in-vitro cytotoxicity studies
    Authors: S Sargazi, S Shahraki, O Shahraki, F Zargari, R Sheervalil, S Maghsoudi, MN Soltani Ra, R Saravani
    Bioorganic chemistry, 2021-04-09;111(0):104900.  2021-04-09
  9. Effects of Bovine Colostrum with or without Egg on In Vitro Bacterial-Induced Intestinal Damage with Relevance for SIBO and Infectious Diarrhea
    Authors: RJ Playford, N Choudhry, P Kelly, T Marchbank
    Nutrients, 2021-03-22;13(3):.  2021-03-22
  10. Apoptotic Effects of Anthocyanins from Vitis coignetiae Pulliat Are Enhanced by Augmented Enhancer of the Rudimentary Homolog (ERH) in Human Gastric Carcinoma MKN28 Cells
    Authors: C Park, WS Lee, SI Go, SH Jeong, J Yoo, HJ Cha, YJ Lee, HS Kim, SH Leem, HJ Kim, GS Kim, SC Hong, YH Choi
    International Journal of Molecular Sciences, 2021-03-16;22(6):.  2021-03-16
  11. Precisely Fabricated Sulpiride-Loaded Nanolipospheres with Ameliorated Oral Bioavailability and Antidepressant Activity
    Authors: SM Mohyeldin, WM Samy, D Ragab, DA Abdelmonsi, RG Aly, NA Elgindy
    International Journal of Nanomedicine, 2021-03-09;16(0):2013-2044.  2021-03-09
  12. Critical implication of the PTEN/PI3K/AKT pathway during BMP2-induced heterotopic ossification
    Authors: J Dong, X Xu, Q Zhang, Z Yuan, B Tan
    Molecular Medicine Reports, 2021-02-04;23(4):.  2021-02-04
  13. Activated ROCK/Akt/eNOS and ET-1/ERK pathways in 5-fluorouracil-induced cardiotoxicity: modulation by simvastatin
    Authors: RN Muhammad, N Sallam, HS El-Abhar
    Sci Rep, 2020-09-07;10(1):14693.  2020-09-07
  14. Hemistepsin A protects human keratinocytes against hydrogen peroxide-induced oxidative stress through activation of the Nrf2/HO-1 signaling pathway
    Authors: C Park, H Lee, JS Noh, CY Jin, GY Kim, JW Hyun, SH Leem, YH Choi
    Arch. Biochem. Biophys., 2020-07-24;691(0):108512.  2020-07-24
  15. Sensitivity of allyl isothiocyanate to induce apoptosis via ER stress and the mitochondrial pathway upon ROS production in colorectal adenocarcinoma cells
    Authors: JH Chiang, FJ Tsai, YM Hsu, MC Yin, HY Chiu, JS Yang
    Oncol. Rep., 2020-07-21;0(0):.  2020-07-21
  16. Potential effects of allyl isothiocyanate on inhibiting cellular proliferation and inducing apoptotic pathway in human cisplatin-resistant oral cancer cells
    Authors: PY Chang, FJ Tsai, DT Bau, YM Hsu, JS Yang, MG Tu, SL Chiang
    J. Formos. Med. Assoc., 2020-07-03;0(0):.  2020-07-03
  17. Nicotine encourages oxidative stress and impairment of rats' brain mitigated by Spirulina platensis lipopolysaccharides and low-dose ionizing radiation
    Authors: SM Elsonbaty, AFM Ismail
    Arch. Biochem. Biophys., 2020-04-25;0(0):108382.  2020-04-25
  18. Hydrophobicity-Tuned Periodic Mesoporous Organo-Silica Nanoparticles for Photodynamic Therapy
    Authors: CH Lin, R Kumar Kank, P Busa, CH Lee
    Int J Mol Sci, 2020-04-08;21(7):.  2020-04-08
  19. New insights in acetaminophen toxicity: HMGB1 contributes by itself to amplify hepatocyte necrosis in vitro through the TLR4-TRIF-RIPK3 axis
    Authors: C Minsart, C Liefferinc, A Lemmers, C Dressen, E Quertinmon, I Leclercq, J Devière, R Moreau, T Gustot
    Sci Rep, 2020-03-27;10(1):5557.  2020-03-27
  20. The Effects of Inhibition of MicroRNA-375 in a Mouse Model of Doxorubicin-Induced Cardiac Toxicity
    Authors: H Zhang, Y Tian, D Liang, Q Fu, L Jia, D Wu, X Zhu
    Med. Sci. Monit., 2020-03-18;26(0):e920557.  2020-03-18
  21. MicroRNA-143 Increases Oxidative Stress and Myocardial Cell Apoptosis in a Mouse Model of Doxorubicin-Induced Cardiac Toxicity
    Authors: XQ Li, YK Liu, J Yi, JS Dong, PP Zhang, L Wan, K Li
    Med. Sci. Monit., 2020-03-14;26(0):e920394.  2020-03-14
  22. l-Theanine improves functional recovery after traumatic spinal cord injury in rats
    Authors: CC Yang, KC Chang, MH Wang, HC Tseng, HS Soung, CH Fang, YW Lin, KY Li, CC Tsai
    J. Formos. Med. Assoc., 2019-12-05;0(0):.  2019-12-05
  23. Pan-caspase inhibitor F573 mitigates liver ischemia reperfusion injury in a murine model
    Authors: M Bral, R Pawlick, B Marfil-Gar, N Dadheech, J Hefler, A Thiesen, AMJ Shapiro
    PLoS ONE, 2019-11-26;14(11):e0224567.  2019-11-26
  24. Iron Overload Damages the Endothelial Mitochondria via the ROS/ADMA/DDAHII/eNOS/NO Pathway
    Authors: H He, Y Qiao, Q Zhou, Z Wang, X Chen, D Liu, D Yin, M He
    Oxid Med Cell Longev, 2019-11-12;2019(0):2340392.  2019-11-12
  25. Isorhamnetin Induces Cell Cycle Arrest and Apoptosis Via Reactive Oxygen Species-Mediated AMP-Activated Protein Kinase Signaling Pathway Activation in Human Bladder Cancer Cells
    Authors: C Park, HJ Cha, EO Choi, H Lee, H Hwang-Bo, SY Ji, MY Kim, SY Kim, SH Hong, J Cheong, GY Kim, SJ Yun, HJ Hwang, WJ Kim, YH Choi
    Cancers (Basel), 2019-10-04;11(10):.  2019-10-04
  26. A comparative study: the prospective influence of nanovectors in leveraging the chemopreventive potential of COX-2 inhibitors against skin cancer
    Authors: NK Abo Aasy, D Ragab, MA Sallam, DA Abdelmonsi, RG Aly, KA Elkhodairy
    Int J Nanomedicine, 2019-09-17;14(0):7561-7581.  2019-09-17
  27. High Concentration of C5a-Induced Mitochondria-Dependent Apoptosis in Murine Kidney Endothelial Cells
    Authors: IJ Tsai, WC Lin, YH Yang, YL Tseng, YH Lin, CH Chou, YK Tsau
    Int J Mol Sci, 2019-09-10;20(18):.  2019-09-10
  28. CRM197 reverses paclitaxel resistance by inhibiting the NAC-1/Gadd45 pathway in paclitaxel-resistant ovarian cancer cells
    Authors: XH Tang, H Li, XS Zheng, MS Lu, Y An, XL Zhang
    Cancer Med, 2019-09-06;0(0):.  2019-09-06
  29. Derrone induces autophagic cell death through induction of ROS and ERK in A549 cells
    Authors: MJ Kang, SY Kim, EB Kwon, YH Jo, MK Lee, HS Lee, DO Moon, MO Kim
    PLoS ONE, 2019-06-19;14(6):e0218659.  2019-06-19
  30. Influence of salinity on spermatogenesis in adult Nile tilapia (Oreochromis niloticus) testis
    Authors: AB Cruz Vieir, AA Weber, YM Ribeiro, RK Luz, N Bazzoli, E Rizzo
    Theriogenology, 2019-03-21;131(0):1-8.  2019-03-21
  31. Dexmedetomidine Attenuates Lung Injury by Promoting Mitochondrial Fission and Oxygen Consumption
    Authors: JR Zhang, Q Lin, FQ Liang, T Xie
    Med. Sci. Monit., 2019-03-11;25(0):1848-1856.  2019-03-11
  32. Structural characterization and in vitro antitumor activity of A polysaccharide from Artemisia annua L. (Huang Huahao)
    Authors: L Yan, C Xiong, P Xu, J Zhu, Z Yang, H Ren, Q Luo
    Carbohydr Polym, 2019-02-25;213(0):361-369.  2019-02-25
  33. Synergistic study of a Danshen (Salvia Miltiorrhizae Radix et Rhizoma) and Sanqi (Notoginseng Radix et Rhizoma) combination on cell survival in EA.hy926 cells
    Authors: X Zhou, V Razmovski-, A Kam, D Chang, CG Li, K Chan, A Bensoussan
    BMC Complement Altern Med, 2019-02-21;19(1):50.  2019-02-21
  34. Efficient biofunctionalization of MoS2 nanosheets with peptides as intracellular fluorescent biosensor for sensitive detection of caspase-3 activity
    Authors: X Li, Y Li, Q Qiu, Q Wen, Q Zhang, W Yang, L Yuwen, L Weng, L Wang
    J Colloid Interface Sci, 2019-02-04;543(0):96-105.  2019-02-04
  35. Cilostazol protects hepatocytes against alcohol-induced apoptosis via activation of AMPK pathway
    Authors: YJ Lee, MS Shu, JY Kim, YH Kim, KH Sim, WJ Sung, JR Eun
    PLoS ONE, 2019-01-29;14(1):e0211415.  2019-01-29
  36. The effects and mechanism of peiminine-induced apoptosis in human hepatocellular carcinoma HepG2 cells
    Authors: X Chao, G Wang, Y Tang, C Dong, H Li, B Wang, J Wu, J Zhao
    PLoS ONE, 2019-01-07;14(1):e0201864.  2019-01-07
  37. Camalexin Induces Apoptosis via the ROS-ER Stress-Mitochondrial Apoptosis Pathway in AML Cells
    Authors: Y Yang, G Wang, W Wu, S Yao, X Han, D He, J He, G Zheng, Y Zhao, Z Cai, R Yu
    Oxid Med Cell Longev, 2018-11-14;2018(0):7426950.  2018-11-14
  38. Manilkara zapota (L.) P. Royen Leaf Water Extract Induces Apoptosis in Human Hepatocellular Carcinoma (HepG2) Cells via ERK1/2/Akt1/JNK1 Signaling Pathways
    Authors: BL Tan, ME Norhaizan, LC Chan
    Evid Based Complement Alternat Med, 2018-11-05;2018(0):7826576.  2018-11-05
  39. Design, synthesis, biological evaluation and dynamics simulation of indazole derivatives with antiangiogenic and antiproliferative anticancer activity
    Authors: NMY Elsayed, RAT Serya, MF Tolba, M Ahmed, K Barakat, DA Abou El El, KAM Abouzid
    Bioorg. Chem., 2018-11-02;82(0):340-359.  2018-11-02
  40. Collagen regulates the ability of endothelial progenitor cells to protect hypoxic myocardium through a mechanism involving miR-377/VE-PTP axis
    Authors: AM Rosca, DN Mitroi, V Cismasiu, R Badea, G Necula-Pet, MB Preda, C Niculite, R Tutuianu, S Szedlacsek, A Burlacu
    J. Cell. Mol. Med., 2018-07-25;0(0):.  2018-07-25
  41. Camel Milk Ameliorates 5-Fluorouracil-Induced Renal Injury in Rats: Targeting MAPKs, NF-?B and PI3K/Akt/eNOS Pathways
    Authors: HH Arab, SA Salama, IA Maghrabi
    Cell. Physiol. Biochem., 2018-04-20;46(4):1628-1642.  2018-04-20
  42. LncRNA TP73-AS1 predicts the prognosis of bladder cancer patients and functions as a suppressor for bladder cancer by EMT pathway
    Authors: Z Tuo, J Zhang, W Xue
    Biochem. Biophys. Res. Commun., 2018-04-11;0(0):.  2018-04-11
  43. Reactive oxygen species-dependent apoptosis induction by water extract ofCitrus unshiupeel in MDA-MB-231 human breast carcinoma cells
    Authors: MY Kim, EO Choi, H HwangBo, DH Kwon, KI Ahn, HJ Kim, SY Ji, SH Hong, JW Jeong, GY Kim, C Park, YH Choi
    Nutr Res Pract, 2018-03-21;12(2):129-134.  2018-03-21
  44. Effects of glabridin combined with 5-fluorouracil on the proliferation and apoptosis of gastric cancer cells
    Authors: L Zhang, H Chen, M Wang, X Song, F Ding, J Zhu, X Li
    Oncol Lett, 2018-03-14;15(5):7037-7045.  2018-03-14
  45. LncRNA SNHG16 Functions as an Oncogene by Sponging MiR-4518 and Up-Regulating PRMT5 Expression in Glioma
    Authors: YF Lu, XL Cai, ZZ Li, J Lv, YA Xiang, JJ Chen, WJ Chen, WY Sun, XM Liu, JB Chen
    Cell. Physiol. Biochem., 2018-03-06;45(5):1975-1985.  2018-03-06
  46. Staphylococcus aureus triggers a shift from influenza virus-induced apoptosis to necrotic cell death
    Authors: A van Krücht, JJ Wilden, S Niemann, G Peters, B Löffler, S Ludwig, C Ehrhardt
    FASEB J., 2018-01-11;0(0):fj201701006R.  2018-01-11
  47. Piceatannol-Induced Apoptosis Is Reversed by N-Acetyl-L-cysteine through Restoration of XIAP Expression
    Authors: CY Jin, IMN Molagoda, C Park, TK Kwon, SJ Yun, WJ Kim, GY Kim, YH Choi
    Biol. Pharm. Bull., 2018-01-01;41(9):1372-1378.  2018-01-01
  48. Epigallocatechin-3-gallate counters cisplatin toxicity of rat testes
    Authors: AA Fouad, HO Qutub, AEA Fouad, AM Audeh, WN Al-Melhim
    Pharm Biol, 2017-12-01;55(1):1710-1714.  2017-12-01
  49. Efficiency of newly formulated camptothecin with ?-cyclodextrin-EDTA-Fe3O4 nanoparticle-conjugated nanocarriers as an anti-colon cancer (HT29) drug
    Authors: P Krishnan, M Rajan, S Kumari, S Sakinah, SP Priya, F Amira, L Danjuma, M Pooi Ling, S Fakurazi, P Arulselvan, A Higuchi, R Arumugam, AA Alarfaj, MA Munusamy, RA Hamat, G Benelli, K Murugan, SS Kumar
    Sci Rep, 2017-09-08;7(1):10962.  2017-09-08
  50. Pterostilbene exerts anticancer activity on non-small-cell lung cancer via activating endoplasmic reticulum stress
    Authors: Z Ma, Y Yang, S Di, X Feng, D Liu, S Jiang, W Hu, Z Qin, Y Li, J Lv, C Fan, X Yan, X Li
    Sci Rep, 2017-08-14;7(1):8091.  2017-08-14
  51. Elucidation of Molecular Mechanisms of Streptozotocin-Induced Oxidative Stress, Apoptosis, and Mitochondrial Dysfunction in Rin-5F Pancreatic ?-Cells
    Authors: AMTA Nahdi, A John, H Raza
    Oxid Med Cell Longev, 2017-08-06;2017(0):7054272.  2017-08-06
  52. Cudraflavone C Induces Apoptosis of A375.S2 Melanoma Cells through Mitochondrial ROS Production and MAPK Activation
    Authors: CW Lee, FL Yen, HH Ko, SY Li, YC Chiang, MH Lee, MH Tsai, LF Hsu
    Int J Mol Sci, 2017-07-13;18(7):.  2017-07-13
  53. Bufalin sensitizes human bladder carcinoma cells to TRAIL-mediated apoptosis
    Authors: KH Kang, MH Han, JW Jeong, C Park, SH Lee, HW Lee, SH Hong, YH Choi, SH Hong
    Oncol Lett, 2017-05-22;14(1):853-859.  2017-05-22
  54. Inhibition of Autophagy Promotes Salinomycin-Induced Apoptosis via Reactive Oxygen Species-Mediated PI3K/AKT/mTOR and ERK/p38 MAPK-Dependent Signaling in Human Prostate Cancer Cells
    Authors: KY Kim, KI Park, SH Kim, SN Yu, SG Park, YW Kim, YK Seo, JY Ma, SC Ahn
    Int J Mol Sci, 2017-05-18;18(5):.  2017-05-18
  55. Long non-coding RNA MALAT1 contributes to cell apoptosis by sponging miR-124 in Parkinson disease
    Authors: W Liu, Q Zhang, J Zhang, W Pan, J Zhao, Y Xu
    Cell Biosci, 2017-04-21;7(0):19.  2017-04-21
  56. Endogenous Two-Photon Excited Fluorescence Imaging Characterizes Neuron and Astrocyte Metabolic Responses to Manganese Toxicity
    Authors: E Stuntz, Y Gong, D Sood, V Liaudanska, D Pouli, KP Quinn, C Alonzo, Z Liu, DL Kaplan, I Georgakoud
    Sci Rep, 2017-04-21;7(1):1041.  2017-04-21
  57. Suberoylanilide hydroxamic acid increases anti-cancer effect of tumor necrosis factor-? through up-regulation of TNF receptor 1 in lung cancer cells.
    Authors: Bo Ra You, Bo Ram Han, Woo Hyun Park
    Oncotarget, 2017-03-14;0(0):1949-2553.  2017-03-14
  58. Disrupting the blood-brain barrier by focused ultrasound induces sterile inflammation
    Proc. Natl. Acad. Sci. U.S.A, 2016-12-19;0(0):.  2016-12-19
  59. Induction of apoptosis by ethanol extract of Evodia rutaecarpa in HeLa human cervical cancer cells via activation of AMP-activated protein kinase
    Authors: Seon Young Park
    Biosci Trends, 2016-11-27;0(0):.  2016-11-27
  60. Hydrogen Peroxide-Responsive Nanoparticle Reduces Myocardial Ischemia/Reperfusion Injury
    J Am Heart Assoc, 2016-11-14;5(11):.  2016-11-14
  61. Upregulation of retinoic acid receptor-? reverses drug resistance in cholangiocarcinoma cells by enhancing susceptibility to apoptosis
    Mol Med Rep, 2016-09-02;14(4):3602-8.  2016-09-02
  62. Bacteroides fragilis Enterotoxin Upregulates Heme Oxygenase-1 in Intestinal Epithelial Cells via a Mitogen-Activated Protein Kinases- and NF-?B-Dependent Pathway, Leading to Modulation of Apoptosis
    Authors: Su Hyuk Ko
    Infect Immun, 2016-08-19;0(0):.  2016-08-19
  63. Euphorbia factor L2 induces apoptosis in A549 cells through the mitochondrial pathway
    Authors: M Lin, S Tang, C Zhang, H Chen, W Huang, Y Liu, J Zhang
    Acta Pharm Sin B, 2016-07-30;7(1):59-64.  2016-07-30
  64. The mitochondrial ubiquitin ligase plays an anti-apoptotic role in cardiomyocytes by regulating mitochondrial fission
    J Cell Mol Med, 2016-07-22;0(0):.  2016-07-22
  65. Anti-Cancer Effect of Lambertianic Acid by Inhibiting the AR in LNCaP Cells
    Int J Mol Sci, 2016-07-07;17(7):.  2016-07-07
  66. Time-resolved studies define the nature of toxic IAPP intermediates, providing insight for anti-amyloidosis therapeutics
    Elife, 2016-05-23;5(0):.  2016-05-23
  67. Pulchrin A, a New Natural Coumarin Derivative of Enicosanthellum pulchrum, Induces Apoptosis in Ovarian Cancer Cells via Intrinsic Pathway
    PLoS ONE, 2016-05-02;11(5):e0154023.  2016-05-02
  68. Diosmin protects against ethanol-induced gastric injury in rats: novel anti-ulcer actions.
    Authors: Arab H, Salama S, Omar H, Arafa E, Maghrabi I
    PLoS ONE, 2015-03-30;10(3):e0122417.  2015-03-30
  69. Erythropoietin protects cardiomyocytes from cell death during hypoxia/reperfusion injury through activation of survival signaling pathways.
    Authors: Parvin A, Pranap R, Shalini U, Devendran A, Baker J, Dhanasekaran A
    PLoS ONE, 2014-09-19;9(9):e107453.  2014-09-19
  70. Augmented efficacy with the combination of blockade of the Notch-1 pathway, bortezomib and romidepsin in a murine MT-1 adult T-cell leukemia model.
    Authors: Yu P, Petrus M, Ju W, Zhang M, Conlon K, Nakagawa M, Maeda M, Bamford R, Waldmann T
    Leukemia, 2014-08-14;29(3):556-66.  2014-08-14
  71. Protective effect of Aframomum melegueta phenolics against CCl(4)-induced rat hepatocytes damage; role of apoptosis and pro-inflammatory cytokines inhibition.
    Authors: El-Halawany A, El Dine R, El Sayed N, Hattori M
    Sci Rep, 2014-07-30;4(0):5880.  2014-07-30
  72. Telmisartan attenuates colon inflammation, oxidative perturbations and apoptosis in a rat model of experimental inflammatory bowel disease.
    Authors: Arab H, Al-Shorbagy M, Abdallah D, Nassar N
    PLoS ONE, 2014-05-15;9(5):e97193.  2014-05-15
  73. Adverse signaling of scavenger receptor class B1 and PGC1s in alcoholic hepatosteatosis and steatohepatitis and protection by betaine in rat.
    Authors: Varatharajalu R, Garige M, Leckey L, Arellanes-Robledo J, Reyes-Gordillo K, Shah R, Lakshman M
    Am J Pathol, 2014-05-06;184(7):2035-44.  2014-05-06
  74. Suberoylanilide hydroxamic acid-induced HeLa cell death is closely correlated with oxidative stress and thioredoxin 1 levels.
    Authors: You B, Park W
    Int J Oncol, 2014-03-12;44(5):1745-55.  2014-03-12
  75. Enhancement of TWIK-related acid-sensitive potassium channel 3 (TASK3) two-pore domain potassium channel activity by tumor necrosis factor alpha.
    Authors: El Hachmane M, Rees K, Veale E, Sumbayev V, Mathie A
    J Biol Chem, 2013-12-04;289(3):1388-401.  2013-12-04
  76. Curcumin-loaded nanoparticles enhance apoptotic cell death of U2OS human osteosarcoma cells through the Akt-Bad signaling pathway.
    Authors: Peng S, Lee C, Hour M, Tsai S, Kuo D, Chen F, Shieh P, Yang J
    Int J Oncol, 2013-11-14;44(1):238-46.  2013-11-14
  77. Upregulation of miR-18a-5p contributes to epidermal necrolysis in severe drug eruptions.
    Authors: Ichihara A, Wang Z, Jinnin M, Izuno Y, Shimozono N, Yamane K, Fujisawa A, Moriya C, Fukushima S, Inoue Y, Ihn H
    J Allergy Clin Immunol, 2013-11-01;133(4):1065-74.  2013-11-01
  78. Soy soluble polysaccharide induces apoptosis in HCT116 human colon cancer cells via reactive oxygen species generation.
    Authors: Ko Y, Jeong J, Choi Y, Ryu C
    Mol Med Rep, 2013-10-14;8(6):1767-72.  2013-10-14
  79. Valproic acid inhibits the growth of HeLa cervical cancer cells via caspase-dependent apoptosis.
    Authors: Han B, You B, Park W
    Oncol Rep, 2013-09-20;30(6):2999-3005.  2013-09-20
  80. Macrophages mediate gemcitabine resistance of pancreatic adenocarcinoma by upregulating cytidine deaminase.
    Authors: Weizman, N, Krelin, Y, Shabtay-Orbach, A, Amit, M, Binenbaum, Y, Wong, R J, Gil, Z
    Oncogene, 2013-09-02;33(29):3812-9.  2013-09-02
  81. Malignant melanoma cells acquire resistance to DNA interstrand cross-linking chemotherapeutics by p53-triggered upregulation of DDB2/XPC-mediated DNA repair.
    Authors: Barckhausen C, Roos W, Naumann S, Kaina B
    Oncogene, 2013-04-22;33(15):1964-74.  2013-04-22
  82. Suppression of neuroinflammatory and apoptotic signaling cascade by curcumin alone and in combination with piperine in rat model of olfactory bulbectomy induced depression.
    Authors: Rinwa P, Kumar A, Garg S
    PLoS ONE, 2013-04-17;8(4):e61052.  2013-04-17
  83. The ameliorative effects of L-2-oxothiazolidine-4-carboxylate on acetaminophen-induced hepatotoxicity in mice.
    Authors: Choi, Jiwon, Park, Kwang-Hy, Kim, Sung Zoo, Shin, Jun Ho, Jang, Seon-Il
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Caspase-3 Colorimetric Assay Kit
By Anonymous on 11/28/2021

Calu-3 human lung cancer cells and A-431 human epidermoid carcinoma cancer cells were treated with Staurosporine (5 μM) for 4 hours or DMSO to induce apoptosis. The cells were then collected, lysed and 150 μg of protein was used to measure Caspase-3 activity at 400 nm, following the instructions of the Caspase-3 Colorimetric Assay Kit (K106-100).