CCK Octapeptide, sulfated
Purity: ≥95%
Biological Activity
CCK Octapeptide, sulfated is an endogenous C-terminal octapeptide of CCK found in the central nervous system and gastrointestinal tract.Non-sulfated Peptide also available.
Technical Data
(Modifications: Tyr-2 = SO3H, Phe-8 = C-terminal amide)
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Additional Information
Background References
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Focal adhesion kinase promotes progression and predicts poor clinical outcomes in patients with osteosarcoma
HJ Gu, B Zhou
Oncol Lett, 2018;15(5):6225-6232. -
CCK biosynthesis and processing: recent progress and future challenges.
Beinfel
Life Sci., 1997;61:2359 -
Characterization of the receptors and mechanisms involved in the cardiovascular actions of sCCK-8 in the pithed rat.
Gaw et al.
Br.J.Pharmacol., 1995;115:660 -
Mediation by CCKB receptors of the CCK-evoked hyperaemia in rat gastric mucosa.
Heinemann et al.
Br.J.Pharmacol., 1995;116:2274 -
G-protein-coupled receptors in gastrointestinal physiology. I. CCK receptors: an exemplary family.
Wank
Am.J.Physiol., 1998;274:G607 -
Guaiacol suppresses osteoclastogenesis by blocking interactions of RANK with TRAF6 and C-Src and inhibiting NF-&kappaB, MAPK and AKT pathways
X Zhi, C Fang, Y Gu, H Chen, X Chen, J Cui, Y Hu, W Weng, Q Zhou, Y Wang, Y Wang, H Jiang, X Li, L Cao, X Chen, J Su
J. Cell. Mol. Med., 2020;0(0):.
Product Datasheets
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Citations for CCK Octapeptide, sulfated
The citations listed below are publications that use Tocris products. Selected citations for CCK Octapeptide, sulfated include:
8 Citations: Showing 1 - 8
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TMEM16B determines cholecystokinin sensitivity of intestinal vagal afferents of nodose neurons.
Authors: Wang Et al.
JCI Insight 2019;4
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A bed nucleus of stria terminalis microcircuit regulating inflammation-associated modulation of feeding.
Authors: Wang Et al.
Nat Commun 2019;10:2769
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Appetite controlled by a cholecystokinin nucleus of the solitary tract to hypothalamus neurocircuit.
Authors: D'Agostino Et al.
Regul Pept 2016;5
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Role of capsaicin-sensitive peripheral sensory neurons in anorexic responses to intravenous infusions of cholecystokinin, peptide YY-(3-36), and glucagon-like peptide-1 in rats.
Authors: Reidelberger Et al.
Am J Physiol Endocrinol Metab 2014;307:E619
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Role of cholecystokinin in anorexia induction following oral exposure to the 8-ketotrichothecenes deoxynivalenol, 15-acetyldeoxynivalenol, 3-acetyldeoxynivalenol, fusarenon X, and nivalenol.
Authors: Wu Et al.
Toxicol Sci 2014;138:278
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Plasminogen activator inhibitor (PAI)-1 suppresses inhibition of gastric emptying by cholecystokinin (CCK) in mice.
Authors: Gamble Et al.
J Neuroendocrinol 2013;185:41518
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CCK stimulation of GLP-1 neurons involves α1-adrenoceptor-mediated increase in glutamatergic synaptic inputs.
Authors: Hisadome Et al.
Diabetes 2011;60:2701
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Effects of cholecystokinin in the supraoptic nucleus and paraventricular nucleus are negatively modulated by leptin in 24-h fasted lean male rats.
Authors: Caquineau Et al.
Autophagy 2010;22:446
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