CGRP 8-37 (human)
Purity: ≥95%
Biological Activity
CGRP 8-37 (human) is a peptide antagonist for CGRP1 receptors.Technical Data
(Modifications: Phe-30 = C-terminal amide)
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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Calcitonin gene-related peptide as a GH secretagogue in human and rat pituitary somatotrophs.
Nakamura et al.
Brain Res., 1998;807:203 -
Pharmacology of receptors for calcitonin gene-related peptide and amylin.
Poyner
TiPS, 1995;16:424 -
Structural determinants for binding to CGRP receptors expressed by human SK-N-MC and Col 29 cells: studies with chimeric and other peptides.
Poyner et al.
Br.J.Pharmacol., 1998;124:1659 -
Pharmacological characterization of CGRP receptors mediating relaxation of the rat pulmonary artery and inhibition of twitch responses of the rat vas deferens.
Wisskirchen et al.
Br.J.Pharmacol., 1998;123:1673
Product Datasheets
Citation for CGRP 8-37 (human)
The citations listed below are publications that use Tocris products. Selected citations for CGRP 8-37 (human) include:
1 Citation: Showing 1 - 1
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Environmental cold exposure increases blood flow and affects pain sensitivity in the knee joints of CFA-induced arthritic mice in a TRPA1-dependent manner.
Authors: Fernandes Et al.
World J Gastroenterol 2016;18:7
FAQs
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