Home / Orphan 7-TM Receptor Antagonists / CID 2745687

CID 2745687

Catalog #: 4293
1 Citation Datasheet / COA / SDS
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4293/10
4293/50
CID 2745687 | CAS No. 264233-05-8 | Orphan 7-TM Receptor Antagonists
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Description: GPR35 antagonist

Chemical Name: 1-(2,4-Difluorophenyl)-5-[[2-[[(1,1-dimethylehyl)amino]thioxomethyl]hydrazinylidene]methyl]-1H-pyrazole-4-carboxylic acid methyl ester

Purity: ≥98%

Product Details
Citations (1)
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Biological Activity

CID 2745687 is a competitive, reversible antagonist of the orphan receptor GPR35 (Ki = 12.8 nM). Blocks the GPR35-mediated increase in ERK1/2 phosphorylation and β-arrestin recruitment induced by pamoic acid.

Technical Data

M.Wt:
395.43
Formula:
C17H19F2N5O2S
Solubility:
Soluble to 100 mM in DMSO and to 10 mM in ethanol
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
264233-05-8

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Citation for CID 2745687

The citations listed below are publications that use Tocris products. Selected citations for CID 2745687 include:

1 Citation: Showing 1 - 1

  1. Label-free cell phenotypic profiling decodes the composition and signaling of an endogenous ATP-sensitive potassium channel.
    Authors: Sun Et al.
    Sci Rep  2014;4:4934

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