Column Rack, holds 5 small or mini cell selection columns
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Citations for Column Rack, holds 5 small or mini cell selection columns
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
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Cross-species transcriptomic analysis identifies mitochondrial dysregulation as a functional consequence of the schizophrenia-associated 3q29 deletion
Authors: RH Purcell, E Sefik, E Werner, AT King, TJ Mosley, ME Merritt-Ga, P Chopra, ZT McEachin, S Karne, N Raj, K Tilahun, M Robinette, ST Warren, Z Wen, V Faundez, SA Sloan, GJ Bassell, JG Mulle
bioRxiv : the preprint server for biology, 2023-05-26;0(0):. 2023-05-26
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Expression, purification and refolding of pro-MMP-2 from inclusion bodies of E. coli
Authors: YN Zhang, JJ Liu, W Zhang, HY Qin, LT Wang, YY Chen, L Yuan, F Yang, RY Cao, XJ Wang
Protein Expression and Purification, 2023-04-23;208(0):106278. 2023-04-23
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TMEM59 ablation leads to loss of olfactory sensory neurons and impairs olfactory functions via interaction with inflammation
Authors: Z Ma, W Li, L Zhuang, T Wen, P Wang, H Yu, Y Liu, Y Yu
Brain, Behavior, and Immunity, 2023-04-13;111(0):151-168. 2023-04-13
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The NK�cell receptor NKp46 recognizes ecto-calreticulin on ER-stressed cells
Authors: S Sen Santar, DJ Lee, Â Crespo, JJ Hu, C Walker, X Ma, Y Zhang, S Chowdhury, KF Meza-Sosa, M Lewandrows, H Zhang, M Rowe, A McClelland, H Wu, C Junqueira, J Lieberman
Nature, 2023-04-05;616(7956):348-356. 2023-04-05
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Golgi organization is a determinant of stem cell function in the small intestine
Authors: S Scharaw, A Sola-Carva, I Belevich, AT Webb, S Das, S Andersson, N Pentinmikk, EJ Villablanc, JR Goldenring, E Jokitalo, RJ Coffey, P Katajisto
bioRxiv : the preprint server for biology, 2023-03-24;0(0):. 2023-03-24
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Tuft cell-derived acetylcholine regulates epithelial fluid secretion
Authors: TE Billipp, C Fung, LM Webeck, DB Sargent, MB Gologorsky, MM McDaniel, DN Kasal, JW McGinty, KA Barrow, LM Rich, A Barilli, M Sabat, JS Debley, R Myers, MR Howitt, J von Moltke
bioRxiv : the preprint server for biology, 2023-03-22;0(0):. 2023-03-22
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IGFBP5 is an ROR1 ligand promoting glioblastoma invasion via ROR1/HER2-CREB signaling axis
Authors: W Lin, R Niu, SM Park, Y Zou, SS Kim, X Xia, S Xing, Q Yang, X Sun, Z Yuan, S Zhou, D Zhang, HJ Kwon, S Park, C Il Kim, H Koo, Y Liu, H Wu, M Zheng, H Yoo, B Shi, JB Park, J Yin
Nature Communications, 2023-03-22;14(1):1578. 2023-03-22
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Corrected and Republished from: "Understanding Lactobacillus paracasei and Streptococcus oralis Biofilm Interactions through Agent-Based Modeling"
Authors: L Archambaul, S Koshy-Chen, A Thompson, A Dongari-Ba, R Laubenbach, P Mendes
mSphere, 2023-03-21;0(0):e0065622. 2023-03-21
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Interaction between PD-L1 and soluble VEGFR1 in glioblastoma-educated macrophages
Authors: X Liu, Z Li, J Sun, Z Zhang, W Li
BMC Cancer, 2023-03-20;23(1):259. 2023-03-20
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Basic Properties of Adipose-Derived Mesenchymal Stem Cells of Rheumatoid Arthritis and Osteoarthritis Patients
Authors: E Kuca-Warna, W Kurowska, M Pleba?czyk, A Wajda, A Kornatka, T Burakowski, I Janicka, P Syrówka, U Skalska
Pharmaceutics, 2023-03-20;15(3):. 2023-03-20
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Targeting Glioblastoma-Associated Macrophages for Photodynamic Therapy Using AGuIX�-Design Nanoparticles
Authors: L Lerouge, M Gries, A Chateau, J Daouk, F Lux, P Rocchi, J Cedervall, AK Olsson, O Tillement, C Frochot, S Acherar, N Thomas, M Barberi-He
Pharmaceutics, 2023-03-20;15(3):. 2023-03-20
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Mapping of clonal lineages across developmental stages in human neural differentiation
Authors: Z You, L Wang, H He, Z Wu, X Zhang, S Xue, P Xu, Y Hong, M Xiong, W Wei, Y Chen
Cell Stem Cell, 2023-03-17;0(0):. 2023-03-17
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Expanding the Chemical Space of Arsenicin A-C Related Polyarsenicals and Evaluation of Some Analogs as Inhibitors of Glioblastoma Stem Cell Growth
Authors: J Vigna, D Sighel, EF Rosatti, A Defant, M Pancher, V Sidarovich, A Quattrone, I Mancini
Marine Drugs, 2023-03-17;21(3):. 2023-03-17
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Generation of a human fibroblast-derived induced pluripotent stem cell line KRIBBi009-A from a patient with breast cancer
Authors: N Son, YS Son, CR Jung, MY Son
Stem Cell Research, 2023-03-14;68(0):103060. 2023-03-14
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Shiga Toxin (Stx) Type 1a and Stx2a Translocate through a Three-Layer Intestinal Model
Authors: RA Bova, AC Lamont, TJ Picou, VB Ho, KH Gilchrist, AR Melton-Cel
Toxins, 2023-03-09;15(3):. 2023-03-09
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Cardiac Hamp mRNA Is Predominantly Expressed in the Right Atrium and Does Not Respond to Iron
Authors: M Bigorra Mi, E Charlebois, S Tsyplenkov, C Fillebeen, K Pantopoulo
International Journal of Molecular Sciences, 2023-03-08;24(6):. 2023-03-08
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RNF130 protects against pulmonary fibrosis through suppressing aerobic glycolysis by mediating c-myc ubiquitination
Authors: J Zhang, W Chen, J Du, L Chu, Z Zhou, W Zhong, D Liu, H Huang, Y Huang, Y Qiao, X Meng, F Zou, S Cai, H Dong
International immunopharmacology, 2023-03-07;117(0):109985. 2023-03-07
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Generation of Schwann cell derived melanocytes from hPSCs identifies pro-metastatic factors in melanoma
Authors: RM Samuel, A Navickas, A Maynard, EA Gaylord, K Garcia, S Bhat, H Majd, MN Richter, N Elder, D Le, P Nguyen, B Shibata, ML Llabata, L Selleri, DJ Laird, S Darmanis, H Goodarzi, F Fattahi
bioRxiv : the preprint server for biology, 2023-03-07;0(0):. 2023-03-07
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hPSC-derived sacral neural crest enables rescue in a severe model of Hirschsprung's disease
Authors: Y Fan, J Hackland, A Baggiolini, LY Hung, H Zhao, P Zumbo, P Oberst, AP Minotti, E Hergenrede, S Najjar, Z Huang, NM Cruz, A Zhong, M Sidharta, T Zhou, E de Stanchi, D Betel, RM White, M Gershon, KG Margolis, L Studer
Cell Stem Cell, 2023-03-02;30(3):264-282.e9. 2023-03-02
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Automating iPSC generation to enable autologous photoreceptor cell replacement therapy
Authors: LR Bohrer, NE Stone, NK Mullin, AP Voigt, KR Anfinson, JL Fick, V Luangphakd, B Hittle, K Powell, GF Muschler, RF Mullins, EM Stone, BA Tucker
Journal of Translational Medicine, 2023-02-28;21(1):161. 2023-02-28
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A dhesion analysis via a tumor vasculature-like microfluidic device identifies CD8+ T�cells with enhanced tumor homing to improve cell therapy
Authors: CP Camargo, AK Muhuri, Y Alapan, LF Sestito, M Khosla, MP Manspeaker, AS Smith, CM Paulos, SN Thomas
Cell Reports, 2023-02-26;42(3):112175. 2023-02-26
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In vitro and in vivo applications of a universal and synthetic thermo-responsive drug delivery hydrogel platform
Authors: H Gholizadeh, E Landh, DM Silva, A Granata, D Traini, P Young, A Fathi, S Maleknia, T Abrams, F Dehghani, H Xin Ong
International journal of pharmaceutics, 2023-02-25;635(0):122777. 2023-02-25
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Dual mechanism: Epigenetic inhibitor apabetalone reduces SARS-CoV-2 Delta and Omicron variant spike binding and attenuates SARS-CoV-2 RNA induced inflammation
Authors: L Fu, D Gilham, SC Stotz, CD Sarsons, BD Rakai, LM Tsujikawa, S Wasiak, JO Johansson, M Sweeney, NCW Wong, E Kulikowski
International immunopharmacology, 2023-02-23;117(0):109929. 2023-02-23
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Fibroblast, Epithelial and Endothelial Cell-Derived Human Cytomegalovirus Strains Display Distinct Neutralizing Antibody Responses and Varying Levels of gH/gL Complexes
Authors: C Fornara, E Schultz, D Lilleri, F Baldanti, B Ryckman, G Gerna
International Journal of Molecular Sciences, 2023-02-23;24(5):. 2023-02-23
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A20 and the non-canonical NF-kappaB pathway are key regulators of neutrophil recruitment during fetal ontogeny
Authors: I Rohwedder, LM Wackerbart, K Heinig, A Ballweg, J Altstätter, M Ripphahn, C Nussbaum, M Salvermose, S Bierschenk, T Straub, M Gunzer, M Schmidt-Su, T Kolben, C Schulz, A Ma, B Walzog, M Heinig, M Sperandio
JCI Insight, 2023-02-22;0(0):. 2023-02-22
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PI3-kinase deletion promotes myelodysplasia by dysregulating autophagy in hematopoietic stem cells
Authors: K Ames, I Kaur, Y Shi, MM Tong, T Sinclair, S Hemmati, SG Glushakow-, E Tein, L Gurska, U Steidl, R Dubin, J Shan, C Montagna, K Pradhan, A Verma, K Gritsman
Science Advances, 2023-02-22;9(8):eade8222. 2023-02-22
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Sugar transporter Slc37a2 regulates bone metabolism in mice via a tubular lysosomal network in osteoclasts
Authors: PY Ng, ABP Ribet, Q Guo, BH Mullin, JWY Tan, E Landao-Bas, S Stephens, K Chen, J Yuan, L Abudulai, M Bollen, ETTT Nguyen, J Kular, JM Papadimitr, K Søe, RD Teasdale, J Xu, RG Parton, H Takayanagi, NJ Pavlos
Nature Communications, 2023-02-21;14(1):906. 2023-02-21
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Hydrogel-Based Pre-Clinical Evaluation of Repurposed FDA-Approved Drugs for AML
Authors: JR James, J Curd, JC Ashworth, M Abuhantash, M Grundy, CH Seedhouse, KP Arkill, AJ Wright, CLR Merry, A Thompson
International Journal of Molecular Sciences, 2023-02-20;24(4):. 2023-02-20
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TRIM21-dependent target protein ubiquitination mediates cell-free Trim-Away
Authors: TET Mevissen, AV Prasad, JC Walter
Cell Reports, 2023-02-18;42(2):112125. 2023-02-18
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Astrocytic TIMP-1 regulates production of Anastellin, a novel inhibitor of oligodendrocyte differentiation and FTY720 responses
Authors: PA Sutter, CM Willis, A Menoret, AM Nicaise, A Sacino, AH Sikkema, E Jellison, KK Win, DK Han, W Church, W Baron, AT Vella, SJ Crocker
bioRxiv : the preprint server for biology, 2023-02-18;0(0):. 2023-02-18
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Identification of cell-biologic mechanisms of coronary artery spasm and its ex vivo diagnosis using peripheral blood-derived iPSCs
Authors: HM Yang, JE Lee, JY Kim, J You, J Kim, HS Lee, HM Yoo, MG Kong, JK Han, HJ Cho, KW Park, HJ Kang, BK Koo, YB Park, HS Kim
Biomaterials research, 2023-02-18;27(1):16. 2023-02-18
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C3a-C3aR signaling is a novel modulator of skeletal homeostasis
Authors: MB Kuhn, HS VandenBerg, AJ Reynolds, MD Carson, AJ Warner, AC LaRue, CM Novince, JD Hathaway-S
Bone Reports, 2023-02-16;18(0):101662. 2023-02-16
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SVEP1 is an endogenous ligand for the orphan receptor PEAR1
Authors: JS Elenbaas, U Pudupakkam, KJ Ashworth, CJ Kang, V Patel, K Santana, IH Jung, PC Lee, KH Burks, JM Amrute, RP Mecham, CM Halabi, A Aliso, J Di Paola, NO Stitziel
Nature Communications, 2023-02-15;14(1):850. 2023-02-15
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ATG16L1 protects from interferon-gamma-induced cell death in the small intestinal crypt
Authors: EG Foerster, DKL Tsang, S Goyal, SJ Robertson, LM Robert, H Maughan, CJ Streutker, SE Girardin, DJ Philpott
Mucosal Immunology, 2023-02-14;0(0):. 2023-02-14
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A vector-encoded bispecific killer engager to harness virus-activated NK cells as anti-tumor effectors
Authors: A Floerching, JE Klein, MSC Finkbeiner, TE Schäfer, G Fuchs, J Doerner, H Zirngibl, M Ackermann, HM Kvasnicka, KA Chester, D Jäger, CR Ball, G Ungerechts, CE Engeland
Cell Death & Disease, 2023-02-10;14(2):104. 2023-02-10
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A Potent and Selective CDKL5/GSK3 Chemical Probe is Neuroprotective
Authors: HW Ong, Y Liang, W Richardson, ER Lowry, CI Wells, X Chen, M Silvestre, K Dempster, JA Silvaroli, JL Smith, H Wichterle, NS Pabla, SK Ultanir, AN Bullock, DH Drewry, AD Axtman
bioRxiv : the preprint server for biology, 2023-02-10;0(0):. 2023-02-10
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Matrine regulates Th1/Th2 inflammatory responses by inhibiting the Hsp90/NF-kappaB signaling axis to alleviate atopic dermatitis
Authors: P Huang, F Hu, ZB Yang, Y Pan, R Zhou, YN Yan, HZ Wang, C Wang
The Kaohsiung journal of medical sciences, 2023-02-09;0(0):. 2023-02-09
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Deletion of Annexin A1 in Mice Upregulates the Expression of Its Receptor, Fpr2/3, and Reactivity to the AnxA1 Mimetic Peptide in Platelets
Authors: O Zharkova, MF Salamah, MV Babak, E Rajan, LHK Lim, F Andrade, CD Gil, SM Oliani, LA Moraes, S Vaiyapuri
International Journal of Molecular Sciences, 2023-02-08;24(4):. 2023-02-08
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Selective Transcription Factor Blockade Reduces Human Retinal Endothelial Cell Expression of Intercellular Adhesion Molecule-1 and Leukocyte Binding
Authors: Y Ma, LM Ashander, B Appukuttan, FJ Ryan, ACR Tan, JM Matthews, MZ Michael, DJ Lynn, JR Smith
International Journal of Molecular Sciences, 2023-02-07;24(4):. 2023-02-07
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Probucol suppresses osteoclastogenesis via activating Nrf2 signaling and ameliorates ovariectomy-induced bone loss
Authors: J Guo, R Ren, Z Guo, K Sun, J He, J Shao, X Wang
International immunopharmacology, 2023-02-07;116(0):109820. 2023-02-07
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Micro Ribonucleic Acid-29a (miR-29a) Antagonist Normalizes Bone Metabolism in Osteogenesis Imperfecta (OI) Mice Model
Authors: JY Ko, FS Wang, SH Chen, SJ Kuo
Biomedicines, 2023-02-05;11(2):. 2023-02-05
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Development of a TGFbeta-IL-2/15 Switch Receptor for Use in Adoptive Cell Therapy
Authors: C Beck, NP Casey, I Persiconi, NN Moharrami, A Sike, Y Jin, JA Kyte
Biomedicines, 2023-02-04;11(2):. 2023-02-04
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Differential Modulation of Human M1 and M2 Macrophage Activity by ICOS-Mediated ICOSL Triggering
Authors: CL Gigliotti, C Dianzani, I Stoppa, C Monge, S Sutti, D Sblattero, C Puricelli, R Rolla, U Dianzani, E Boggio
International Journal of Molecular Sciences, 2023-02-02;24(3):. 2023-02-02
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Generation and expansion of transitional lung organoids from human pluripotent stem cells
Authors: IM Leko, N Schrode, J Torres, M Pezet, TA Thimraj, KG Beaumont, HW Snoeck
bioRxiv : the preprint server for biology, 2023-02-01;0(0):. 2023-02-01
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Nanoparticulate MgH2 ameliorates anxiety/depression-like behaviors in a mouse model of multiple sclerosis by regulating microglial polarization and oxidative stress
Authors: Z Li, K Chen, Q Shao, H Lu, X Zhang, Y Pu, X Sun, H He, L Cao
Journal of Neuroinflammation, 2023-01-30;20(1):16. 2023-01-30
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Characterization of large extracellular vesicles (L-EV) derived from human regulatory macrophages (Mreg): novel mediators in wound healing and angiogenesis?
Authors: M Albrecht, L Hummitzsch, R Rusch, K He beta, M Steinfath, J Cremer, F Lichte, F Fändrich, R Berndt, K Zitta
Journal of Translational Medicine, 2023-01-30;21(1):61. 2023-01-30
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Insulin Receptor Substrate 1 Signaling Inhibits Foxp3 Expression and Suppressive Functions in Treg Cells through the mTORC1 Pathway
Authors: WH Lee, GE Kim, KJ Hong, HS Kim, GR Lee
International Journal of Molecular Sciences, 2023-01-29;24(3):. 2023-01-29
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Polyamine metabolism impacts T cell dysfunction in the oral mucosa of people living with HIV
Authors: SS Mahalingam, S Jayaraman, N Bhaskaran, E Schneider, F Faddoul, A Paes da Si, MM Lederman, R Asaad, K Adkins-Tra, LP Shriver, P Pandiyan
Nature Communications, 2023-01-25;14(1):399. 2023-01-25
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Epigenetic and transcriptional regulations prime cell fate before division during human pluripotent stem cell differentiation
Authors: P Madrigal, S Deng, Y Feng, S Militi, KJ Goh, R Nibhani, R Grandy, A Osnato, D Ortmann, S Brown, S Pauklin
Nature Communications, 2023-01-25;14(1):405. 2023-01-25
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Tissue CD14+CD8+ T cells reprogrammed by myeloid cells and modulated by LPS
Authors: LJ Pallett, L Swadling, M Diniz, AA Maini, M Schwabenla, AD Gasull, J Davies, S Kucykowicz, JK Skelton, N Thomas, NM Schmidt, OE Amin, US Gill, KA Stegmann, AR Burton, E Stephenson, G Reynolds, M Whelan, J Sanchez, R de Maeyer, C Thakker, K Suveizdyte, I Uddin, AM Ortega-Pri, C Grant, F Froghi, G Fusai, S Lens, S Pérez-Del-, W Al-Akkad, G Mazza, M Noursadegh, A Akbar, PTF Kennedy, BR Davidson, M Prinz, BM Chain, M Haniffa, DW Gilroy, M Dorner, B Bengsch, A Schurich, MK Maini
Nature, 2023-01-25;614(7947):334-342. 2023-01-25
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Opposing Effects of Interleukin-36gamma and Interleukin-38 on Trained Immunity
Authors: LU Teufel, MG Netea, FL van de Vee, CA Dinarello, LAB Joosten, RJW Arts
International Journal of Molecular Sciences, 2023-01-24;24(3):. 2023-01-24
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The D405N Mutation in the Spike Protein of SARS-CoV-2 Omicron BA.5 Inhibits Spike/Integrins Interaction and Viral Infection of Human Lung Microvascular Endothelial Cells
Authors: A Bugatti, F Filippini, S Messali, M Giovanetti, C Ravelli, A Zani, M Ciccozzi, A Caruso, F Caccuri
Viruses, 2023-01-24;15(2):. 2023-01-24
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Autofluorescence lifetime imaging classifies human lymphocyte activation and subtype
Authors: RL Schmitz, KE Tweed, P Rehani, K Samimi, J Riendeau, I Jones, EM Maly, EC Guzman, MH Forsberg, A Shahi, CM Capitini, AJ Walsh, MC Skala
bioRxiv : the preprint server for biology, 2023-01-23;0(0):. 2023-01-23
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An atlas of lamina-associated chromatin across twelve human cell types reveals an intermediate chromatin subtype
Authors: PP Shah, KC Keough, K Gjoni, GT Santini, RJ Abdill, NM Wickramasi, CE Dundes, A Karnay, A Chen, REA Salomon, PJ Walsh, SC Nguyen, S Whalen, EF Joyce, KM Loh, N Dubois, KS Pollard, R Jain
Genome Biology, 2023-01-23;24(1):16. 2023-01-23
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Immunoproteasome inhibition prevents progression of castration-resistant prostate cancer
Authors: J Li, N Liu, H Zhou, P Xian, Y Song, X Tang, Y Li, M Basler
British Journal of Cancer, 2023-01-21;0(0):. 2023-01-21
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Studies with neutralizing antibodies suggest CXCL8-mediated neutrophil activation is independent of C-C motif chemokine receptor-like 2 (CCRL2) ligand binding function
Authors: Z Su, J Brooks, J Pelker, T Andreyeva, H Sobon, R Gifford, M Powers, J Wang, C Dower, M Hegen, D Messing, AD Sheehan, JJ Brennan
PLoS ONE, 2023-01-20;18(1):e0280590. 2023-01-20
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Hypoxia-tolerant apical-out intestinal organoids to model host-microbiome interactions
Authors: P Kakni, B Jutten, D Teixeira O, J Penders, R Truckenmül, P Habibovic, S Giselbrech
Journal of tissue engineering, 2023-01-18;14(0):2041731422114. 2023-01-18
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Stem cell-nanomedicine system as a theranostic bio-gadolinium agent for targeted neutron capture cancer therapy
Authors: YH Lai, CY Su, HW Cheng, CY Chu, LB Jeng, CS Chiang, WC Shyu, SY Chen
Nature Communications, 2023-01-18;14(1):285. 2023-01-18
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Equine Arteritis Virus in Monocytic Cells Suppresses Differentiation and Function of Dendritic Cells
Authors: NA Moyo, D Westcott, R Simmonds, F Steinbach
Viruses, 2023-01-16;15(1):. 2023-01-16
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The Generation of Human iPSC Lines from Three Individuals with Dravet Syndrome and Characterization of Neural Differentiation Markers in iPSC-Derived Ventral Forebrain Organoid Model
Authors: V Zayat, Z Kuczynska, M Liput, E Metin, S Rzonca-Nie, M Smyk, T Mazurczak, A Goszczansk, P Leszczynsk, D Hoffman-Za, L Buzanska
Cells, 2023-01-16;12(2):. 2023-01-16
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Early Permissiveness of Central Nervous System Cells to Measles Virus Infection Is Determined by Hyperfusogenicity and Interferon Pressure
Authors: M Ferren, A Lalande, M Iampietro, L Canus, D Decimo, D Gerlier, M Porotto, C Mathieu
Viruses, 2023-01-13;15(1):. 2023-01-13
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Conventional Type I Migratory CD103+ Dendritic Cells are Required for Corneal Allograft Survival
Authors: T Blanco, R Bir Singh, H Nakagawa, Y Taketani, TH Dohlman, Y Chen, SK Chauhan, J Yin, R Danan
Mucosal Immunology, 2023-01-13;0(0):. 2023-01-13
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A specific G9a inhibitor unveils BGLT3 lncRNA as a universal mediator of chemically induced fetal globin gene expression
Authors: S Takase, T Hiroyama, F Shirai, Y Maemoto, A Nakata, M Arata, S Matsuoka, T Sonoda, H Niwa, S Sato, T Umehara, M Shirouzu, Y Nishigaya, T Sumiya, N Hashimoto, R Namie, M Usui, T Ohishi, SI Ohba, M Kawada, Y Hayashi, H Harada, T Yamaguchi, Y Shinkai, Y Nakamura, M Yoshida, A Ito
Nature Communications, 2023-01-12;14(1):23. 2023-01-12
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Osthole Inhibits M1 Macrophage Polarization and Attenuates Osteolysis in a Mouse Skull Model
Authors: F Wang, P Yang, T Wan, C Liu, Y Zhu, X Chen, H Liu
Oxidative Medicine and Cellular Longevity, 2023-01-12;2023(0):2975193. 2023-01-12
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A TREM2-activating antibody with a blood-brain barrier transport vehicle enhances microglial metabolism in Alzheimer's disease models
Authors: B van Lenger, L Zhan, D Xia, D Chan, D Joy, JI Park, D Tatarakis, M Calvert, S Hummel, S Lianoglou, ME Pizzo, R Prorok, E Thomsen, LM Bartos, P Beumers, A Capell, SS Davis, L de Weerd, JC Dugas, J Duque, T Earr, K Gadkar, T Giese, A Gill, J Gnörich, C Ha, M Kannuswamy, DJ Kim, ST Kunte, LH Kunze, D Lac, K Lechtenber, AW Leung, CC Liang, I Lopez, P McQuade, A Modi, VO Torres, HN Nguyen, I Pesämaa, N Propson, M Reich, Y Robles-Col, K Schlepckow, L Slemann, H Solanoy, JH Suh, RG Thorne, C Vieira, K Wind-Mark, K Xiong, YJY Zuchero, D Diaz, MS Dennis, F Huang, K Scearce-Le, RJ Watts, C Haass, JW Lewcock, G Di Paolo, M Brendel, PE Sanchez, KM Monroe
Nature Neuroscience, 2023-01-12;0(0):. 2023-01-12
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Targeting TBK1 to overcome resistance to cancer immunotherapy
Authors: Y Sun, OY Revach, S Anderson, EA Kessler, CH Wolfe, A Jenney, CE Mills, EJ Robitschek, TGR Davis, S Kim, A Fu, X Ma, J Gwee, P Tiwari, PP Du, P Sindurakar, J Tian, A Mehta, AM Schneider, K Yizhak, M Sade-Feldm, T LaSalle, T Sharova, H Xie, S Liu, WA Michaud, R Saad-Beret, KB Yates, A Iracheta-V, JKE Spetz, X Qin, KA Sarosiek, G Zhang, JW Kim, MY Su, AM Cicerchia, MQ Rasmussen, SJ Klempner, D Juric, SI Pai, DM Miller, A Giobbie-Hu, JH Chen, K Pelka, DT Frederick, S Stinson, E Ivanova, AR Aref, CP Paweletz, DA Barbie, DR Sen, DE Fisher, RB Corcoran, N Hacohen, PK Sorger, KT Flaherty, GM Boland, RT Manguso, RW Jenkins
Nature, 2023-01-12;0(0):. 2023-01-12
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Targeting CD74 in B-cell non-Hodgkin lymphoma with the antibody-drug conjugate STRO-001
Authors: X Li, C Abrahams, A Yu, M Embry, R Henningsen, V DeAlmeida, S Matheny, T Kline, A Yam, R Stafford, T Hallam, M Lupher, A Molina
Oncotarget, 2023-01-12;14(0):1-13. 2023-01-12
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Upregulation of Robo4 expression by SMAD signaling suppresses vascular permeability and mortality in endotoxemia and COVID-19 models
Authors: M Morita, A Yoneda, N Tokunoh, T Masaki, K Shirakura, M Kinoshita, R Hashimoto, N Shigesada, J Takahashi, M Tachibana, S Tanaka, M Obana, N Hino, M Ikawa, K Tsujikawa, C Ono, Y Matsuura, H Kidoya, N Takakura, Y Kubota, T Doi, K Takayama, Y Yoshioka, Y Fujio, Y Okada
Proceedings of the National Academy of Sciences of the United States of America, 2023-01-12;120(3):e2213317120. 2023-01-12
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The Mechanism of Osteoprotegerin-Induced Osteoclast Pyroptosis In Vitro
Authors: J Zhu, Y Ma, J Wang, Y Wang, W Ali, H Zou, H Zhao, X Tong, R Song, Z Liu
International Journal of Molecular Sciences, 2023-01-12;24(2):. 2023-01-12
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METTL3 Regulates Osteoclast Biological Behaviors via iNOS/NO-Mediated Mitochondrial Dysfunction in Inflammatory Conditions
Authors: D Li, J He, C Fang, Y Zhang, M He, Z Zhang, J Hou, Q Xu
International Journal of Molecular Sciences, 2023-01-11;24(2):. 2023-01-11
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gammadelta T cells are effectors of immunotherapy in cancers with HLA class I defects
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Dietary oxidized frying oil activates hepatic stellate cells and accelerates the severity of carbon tetrachloride- and thioacetamide-induced liver fibrosis in mice
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HIF-1alpha accumulation in response to transient hypoglycemia may worsen diabetic eye disease
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Changes in type 2 innate lymphoid cells and serum cytokines in sublingual immunotherapy in pediatric patients with allergic rhinitis
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RBM43 links adipose inflammation and energy expenditure through translational regulation of PGC1alpha
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Host Cationic Antimicrobial Molecules Inhibit S. aureus Exotoxin Production
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CD27-Expressing Xenoantigen-Expanded Human Regulatory T Cells Are Efficient in Suppressing Xenogeneic Immune Response
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Studies with neutralizing antibodies suggest CXCL8-mediated neutrophil activation is independent of C-C motif chemokine receptor-like 2 (CCRL2) ligand binding function
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The D405N Mutation in the Spike Protein of SARS-CoV-2 Omicron BA.5 Inhibits Spike/Integrins Interaction and Viral Infection of Human Lung Microvascular Endothelial Cells
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Nanoparticulate MgH2 ameliorates anxiety/depression-like behaviors in a mouse model of multiple sclerosis by regulating microglial polarization and oxidative stress
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Identification of cell-biologic mechanisms of coronary artery spasm and its ex vivo diagnosis using peripheral blood-derived iPSCs
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Early Permissiveness of Central Nervous System Cells to Measles Virus Infection Is Determined by Hyperfusogenicity and Interferon Pressure
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A Potent and Selective CDKL5/GSK3 Chemical Probe is Neuroprotective
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In vitro and in vivo applications of a universal and synthetic thermo-responsive drug delivery hydrogel platform
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hPSC-derived sacral neural crest enables rescue in a severe model of Hirschsprung's disease
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CD27-Expressing Xenoantigen-Expanded Human Regulatory T Cells Are Efficient in Suppressing Xenogeneic Immune Response
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ATG16L1 protects from interferon-gamma-induced cell death in the small intestinal crypt
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Mucosal Immunology, 2023;0(0):. 2023
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C3a-C3aR signaling is a novel modulator of skeletal homeostasis
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Astrocytic TIMP-1 regulates production of Anastellin, a novel inhibitor of oligodendrocyte differentiation and FTY720 responses
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bioRxiv : the preprint server for biology, 2023;0(0):. 2023
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METTL3 Regulates Osteoclast Biological Behaviors via iNOS/NO-Mediated Mitochondrial Dysfunction in Inflammatory Conditions
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International Journal of Molecular Sciences, 2023;24(2):. 2023
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Immunoproteasome inhibition prevents progression of castration-resistant prostate cancer
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Host Cationic Antimicrobial Molecules Inhibit S. aureus Exotoxin Production
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The Mechanism of Osteoprotegerin-Induced Osteoclast Pyroptosis In Vitro
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Conventional Type I Migratory CD103+ Dendritic Cells are Required for Corneal Allograft Survival
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Mucosal Immunology, 2023;0(0):. 2023
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Single-Cell Transcriptomic Profiles of Lung Pre-Metastatic Niche Reveal Neutrophil and Lymphatic Endothelial Cell Roles in Breast Cancer
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Cancers, 2022-12-28;15(1):. 2022-12-28
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Bone Marrow-Derived Vasculogenic Mesenchymal Stem Cells Enhance In Vitro Angiogenic Sprouting of Human Umbilical Vein Endothelial Cells
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Inhibition of triple negative breast cancer-associated inflammation and progression by N- acylethanolamine acid amide hydrolase (NAAA)
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Scientific Reports, 2022-12-23;12(1):22255. 2022-12-23
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Engineering of immunoinstructive extracellular matrices for enhanced osteoinductivity
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The Soluble Fms-like Tyrosine Kinase-1 Contributes to Structural and Functional Changes in Endothelial Cells in Chronic Kidney Disease
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The BNT162b2 mRNA SARS-CoV-2 vaccine induces transient afucosylated IgG1 in naive but not in antigen-experienced vaccinees
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Therapeutic effect of ibrutinib, a selective Bruton's tyrosine kinase inhibitor, in orbital fibroblasts from patients with Graves' orbitopathy
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PLoS ONE, 2022-12-15;17(12):e0279060. 2022-12-15
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Nature Immunology, 2022-12-01;0(0):. 2022-12-01
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Interactions between Major Bioactive Polyphenols of Sugarcane Top: Effects on Human Neural Stem Cell Differentiation and Astrocytic Maturation
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Upregulation of PCED1B-AS1 in proliferative diabetic retinopathy and its involvement in retinal vascular endothelial cell proliferation
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BMC ophthalmology, 2022-11-23;22(1):450. 2022-11-23
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Simultaneous depletion of RB, RBL1 and RBL2 affects endoderm differentiation of human embryonic stem cells
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PLoS ONE, 2022-11-22;17(11):e0269122. 2022-11-22
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Tumor-associated macrophages promote resistance of hepatocellular carcinoma cells against sorafenib by activating CXCR2 signaling
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EC-18 prevents autoimmune arthritis by suppressing inflammatory cytokines and osteoclastogenesis
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Inflammatory Cytokines That Enhance Antigen Responsiveness of Na�ve CD8+ T Lymphocytes Modulate Chromatin Accessibility of Genes Impacted by Antigen Stimulation
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7beta-22 Dihydroxyhopane, Isolated from the Sub-Antarctic Lichen, Inhibits the Viability and Stemness in Glioma Stem Like Cells
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OncoTargets and Therapy, 2022-11-15;15(0):1375-1383. 2022-11-15
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Genuine selective caspase-2 inhibition with new irreversible small peptidomimetics
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CD206<sup>+</sup>CD68<sup>+</sup> mono-macrophages and serum soluble CD206 level are increased in antineutrophil cytoplasmic antibodies associated glomerulonephritis
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BMC immunology, 2022-11-15;23(1):55. 2022-11-15
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Inhibiting ACK1-mediated phosphorylation of C-terminal Src kinase counteracts prostate cancer immune checkpoint blockade resistance
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Nature Communications, 2022-11-14;13(1):6929. 2022-11-14
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Atypical E3 ligase ZFP91 promotes small-molecule-induced E2F2 transcription factor degradation for cancer therapy
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EBioMedicine, 2022-11-11;86(0):104353. 2022-11-11
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Cynapanoside A exerts protective effects against obesity-induced diabetic nephropathy through ameliorating TRIM31-mediated inflammation, lipid synthesis and fibrosis
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ST3GAL3 Promotes the Inflammatory Response of Fibroblast-Like Synoviocytes in Rheumatoid Arthritis by Activating the TLR9/MyD88 Pathway
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Mediators of Inflammation, 2022-11-10;2022(0):4258742. 2022-11-10
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Heightened apoptotic priming of vascular cells across tissues and life span predisposes them to cancer therapy-induced toxicities
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Science Advances, 2022-11-09;8(45):eabn6579. 2022-11-09
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Cell Reports, 2022-11-08;41(6):111593. 2022-11-08
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Lateral plate mesoderm cell-based organoid system for NK cell regeneration from human pluripotent stem cells
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Bovine lactoferrin suppresses inflammatory cytokine expression in endometrial stromal cells in chronic endometritis
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Journal of reproductive immunology, 2022-11-08;154(0):103761. 2022-11-08
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Spatial dynamic metabolomics identifies metabolic cell fate trajectories in human kidney differentiation
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Mechanical Compression by Simulating Orthodontic Tooth Movement in an In Vitro Model Modulates Phosphorylation of AKT and MAPKs via TLR4 in Human Periodontal Ligament Cells
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International Journal of Molecular Sciences, 2022-07-22;23(15):. 2022-07-22
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The role of CD101-expressing CD4 T cells in HIV/SIV pathogenesis and persistence
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PloS Pathogens, 2022-07-22;18(7):e1010723. 2022-07-22
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VEGF receptor heterodimers and homodimers are differentially expressed in neuronal and endothelial cell types
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PLoS ONE, 2022-07-21;17(7):e0269818. 2022-07-21
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Dipyridamole for tracking amyloidogenic proteins aggregation and enhancing polyubiquitination
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Archives of biochemistry and biophysics, 2022-07-19;728(0):109354. 2022-07-19
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SMAD3 mutation in LDS3 causes bone fragility by impairing the TGF-beta pathway and enhancing osteoclastogenesis
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Bone Reports, 2022-07-16;17(0):101603. 2022-07-16
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Mechanical force regulates root resorption in rats through RANKL and OPG
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BMC Oral Health, 2022-07-16;22(1):290. 2022-07-16
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Non-coding de novo mutations in chromatin interactions are implicated in autism spectrum disorder
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Oncogene, 2022-07-15;0(0):. 2022-07-15
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CRISPR interference interrogation of COPD GWAS genes reveals the functional significance of desmoplakin in iPSC-derived alveolar epithelial cells
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Oncogene, 2022-07-13;8(28):eabo6566. 2022-07-13
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A Novel Inhibitor INF 39 Promotes Osteogenesis via Blocking the NLRP3/IL-1beta Axis
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BioMed Research International, 2022-07-13;2022(0):7250578. 2022-07-13
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Long-Term Treatment with Bortezomib Induces Specific Methylation Changes in Differentiated Neuronal Cells
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Cancers, 2022-07-13;14(14):. 2022-07-13
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Depression compromises antiviral innate immunity via the AVP-AHI1-Tyk2 axis
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Cell Research, 2022-07-12;0(0):. 2022-07-12
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Oncoprotein DJ-1 interacts with mTOR complexes to effect transcription factor Hif1alpha-dependent expression of collagen I (alpha2) during renal fibrosis
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The Journal of Biological Chemistry, 2022-07-11;0(0):102246. 2022-07-11
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Simple gene signature to assess murine fibroblast polarization
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Nestin-dependent mitochondria-ER contacts define stem Leydig cell differentiation to attenuate male reproductive ageing
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Nature Communications, 2022-07-11;13(1):4020. 2022-07-11
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A cannabidiol aminoquinone derivative activates the PP2A/B55alpha/HIF pathway and shows protective effects in a murine model of traumatic brain injury
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Role of Erythropoietin Receptor Signaling in Macrophages or Choroidal Endothelial Cells in Choroidal Neovascularization
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Biomedicines, 2022-07-09;10(7):. 2022-07-09
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Interleukin-19 Promotes Retinal Neovascularization in a Mouse Model of Oxygen-Induced Retinopathy
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Bimodal regulation of axonal transport by the GDNF-RET signalling axis in healthy and diseased motor neurons
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Synchronous intracellular delivery of EGFR-targeted antibody-drug conjugates by p38-mediated non-canonical endocytosis
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TGFbeta reprograms TNF stimulation of macrophages towards a non-canonical pathway driving inflammatory osteoclastogenesis
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G2019S LRRK2 Mutation Enhances MPP+-Induced Inflammation of Human Induced Pluripotent Stem Cells-Differentiated Dopaminergic Neurons
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Frontiers in Neuroscience, 2022-07-06;16(0):947927. 2022-07-06
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The transcription factor RUNX2 drives the generation of human NK cells and promotes tissue residency
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Super-Resolution Quantification of T2DM-Induced Mitochondrial Morphology Changes and Their Implications in Pharmacodynamics of Metformin and Sorafenib
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Frontiers in Pharmacology, 2022-07-06;13(0):932116. 2022-07-06
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Downregulation of STAT3 in Epstein-Barr Virus-Positive Hodgkin Lymphoma
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Biomedicines, 2022-07-06;10(7):. 2022-07-06
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Chronic Low Dose Morphine Does Not Alter Two In Vitro BBB Models
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Brain sciences, 2022-07-06;12(7):. 2022-07-06
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Long noncoding RNA Smyca coactivates TGF-beta/Smad and Myc pathways to drive tumor progression
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The splicing factor RBM17 drives leukemic stem cell maintenance by evading nonsense-mediated decay of pro-leukemic factors
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Neutralizing Antibodies to Human Cytomegalovirus Recombinant Proteins Reduce Infection in an Ex Vivo Model of Developing Human Placentas
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Vaccines, 2022-07-04;10(7):. 2022-07-04
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Targeted Mutations in the Fusion Peptide Region of La Crosse Virus Attenuate Neuroinvasion and Confer Protection against Encephalitis
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Klotho Modulates Pro-Fibrotic Activities in Human Atrial Fibroblasts through Inhibition of Phospholipase C Signaling and Suppression of Store-Operated Calcium Entry
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11beta-Hydroxysteroid Dehydrogenase Type 1 within Osteoclasts Mediates the Bone Protective Properties of Therapeutic Corticosteroids in Chronic Inflammation
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Dexamethasone Promotes a Stem-Like Phenotype in Human Melanoma Cells via Tryptophan 2,3 Dioxygenase
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Frontiers in Pharmacology, 2022-06-30;13(0):911019. 2022-06-30
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PIK3R3, a regulatory subunit of PI3K, modulates ovarian cancer stem cells and ovarian cancer development and progression by integrative analysis
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BMC Cancer, 2022-06-27;22(1):708. 2022-06-27
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Enhanced In Vitro Expression of Filaggrin and Antimicrobial Peptides Following Application of Glycosaminoglycans and a Sphingomyelin-Rich Lipid Extract
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Cytoplasmic LMO2-LDB1 Complex Activates STAT3 Signaling through Interaction with gp130-JAK in Glioma Stem Cells
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Cells, 2022-06-26;11(13):. 2022-06-26
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Berberine regulates PADI4-related macrophage function to prevent lung cancer
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HIV-1 Nef-mediated downregulation of CD155 results in viral restriction by KIR2DL5+ NK cells
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Oncogene, 2022-06-24;18(6):e1010572. 2022-06-24
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Lmx1a-Dependent Activation of miR-204/211 Controls the Timing of Nurr1-Mediated Dopaminergic Differentiation
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International Journal of Molecular Sciences, 2022-06-23;23(13):. 2022-06-23
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Bone Tissue Engineering in Rat Calvarial Defects Using Induced Bone-like Tissue by rhBMPs from Immature Muscular Tissues In Vitro
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International Journal of Molecular Sciences, 2022-06-22;23(13):. 2022-06-22
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Cbp1, a fungal virulence factor under positive selection, forms an effector complex that drives macrophage lysis
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Oncogene, 2022-06-22;18(6):e1010417. 2022-06-22
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JCI Insight, 2022-06-22;0(0):. 2022-06-22
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Melatonin inhibits osteoclastogenesis via RANKL/OPG suppression mediated by Rev-Erbalpha in osteoblasts
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Oncogene, 2022-06-21;0(0):. 2022-06-21
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CD96 Downregulation Promotes the Immune Response of CD4 T Cells and Associates with Ankylosing Spondylitis
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Oncogene, 2022-06-19;2022(0):3946754. 2022-06-19
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From EGFR kinase inhibitors to anti-inflammatory drugs: Optimization and biological evaluation of (4-(phenylamino)quinazolinyl)-phenylthiourea derivatives as novel NF-kappaB inhibitors
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Bioorganic chemistry, 2022-06-18;127(0):105977. 2022-06-18
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Hyaluronidase 1 deficiency decreases bone mineral density in mice
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Oncogene, 2022-06-16;12(1):10142. 2022-06-16
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Dasatinib and interferon alpha synergistically induce pyroptosis-like cell death in philadelphia chromosome positive acute lymphoblastic leukemia
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American journal of cancer research, 2022-06-15;12(6):2817-2832. 2022-06-15
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Patient-Derived Tumor Organoids for Guidance of Personalized Drug Therapies in Recurrent Glioblastoma
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International Journal of Molecular Sciences, 2022-06-12;23(12):. 2022-06-12
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Design of a US28 ORF Deletion Virus in a Temperature-Sensitive Cytomegalovirus Strain Fails to Promote Lytic Replication in Hematopoietic Cells
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Viruses, 2022-06-12;14(6):. 2022-06-12
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Species-Specific Enhancer Activity of OCT4 in Porcine Pluripotency: The Porcine OCT4 Reporter System Could Monitor Pluripotency in Porcine Embryo Development and Embryonic Stem Cells
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Stem Cells International, 2022-06-11;2022(0):6337532. 2022-06-11
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Pexmetinib suppresses osteoclast formation and breast cancer induced osteolysis via P38/STAT3 signal pathway
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Journal of Bone Oncology, 2022-06-11;35(0):100439. 2022-06-11
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IL-17-producing follicular Th cells enhance plasma cell differentiation in lupus-prone mice
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EBV/HHV-6A dUTPases contribute to myalgic encephalomyelitis/chronic fatigue syndrome pathophysiology by enhancing TFH cell differentiation and extrafollicular activities
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Nature Immunology, 2022-06-06;0(0):. 2022-06-06
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Targeting WEE1/AKT restores p53-dependent NK cell activation to induce immune checkpoint blockade responses in 'cold' melanoma
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Nature Neuroscience, 2022-05-30;25(6):805-817. 2022-05-30
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NLRP3 Inflammasome Negatively Regulates RANKL-Induced Osteoclastogenesis of Mouse Bone Marrow Macrophages but Positively Regulates It in the Presence of Lipopolysaccharides
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Nature Communications, 2022-05-27;13(1):2974. 2022-05-27
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Lipocalin 2 potentially contributes to tumorigenesis from colitis via IL-6/STAT3/NF-kB signaling pathway
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Science Advances, 2022-05-25;8(21):eabj8892. 2022-05-25
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Generation of hiPSC-Derived Skeletal Muscle Cells: Exploiting the Potential of Skeletal Muscle-Derived hiPSCs
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Parkinson's Disease-Specific Autoantibodies against the Neuroprotective Co-Chaperone STIP1
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Gut Metabolite Urolithin A Inhibits Osteoclastogenesis and Senile Osteoporosis by Enhancing the Autophagy Capacity of Bone Marrow Macrophages
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TOPK/PBK is phosphorylated by ERK2 at serine 32, promotes tumorigenesis and is involved in sorafenib resistance in RCC
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Evaluation in a Cytokine Storm Model In Vivo of the Safety and Efficacy of Intravenous Administration of PRS CK STORM (Standardized Conditioned Medium Obtained by Coculture of Monocytes and Mesenchymal Stromal Cells)
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SARS-CoV-2 Envelope (E) Protein Binds and Activates TLR2 Pathway: A Novel Molecular Target for COVID-19 Interventions
Authors: R Planès, JB Bert, S Tairi, L BenMohamed, E Bahraoui
Viruses, 2022-05-08;14(5):. 2022-05-08
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GM-CSF-miRNA-Jak2/Stat3 Signaling Mediates Chemotherapy-Induced Cancer Cell Stemness in Gastric Cancer
Authors: X Xiang, HZ Ma, YQ Chen, DZ Zhang, SX Ma, HJ Wang, DM Liu, Y Yuan, H Cai
Frontiers in Pharmacology, 2022-05-05;13(0):855351. 2022-05-05
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Lipocalin 2 Deficiency Alters Prostaglandin Biosynthesis and mTOR Signaling Regulation of Thermogenesis and Lipid Metabolism in Adipocytes
Authors: J Deis, TY Lin, T Bushman, X Chen
Cells, 2022-05-03;11(9):. 2022-05-03
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Alpha-Linolenic Acid Modulates T Cell Incorporation in a 3D Tissue-Engineered Psoriatic Skin Model
Authors: S Morin, M Simard, G Rioux, P Julien, R Pouliot
Cells, 2022-04-30;11(9):. 2022-04-30
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IFN-gamma and TNF Induce Senescence and a Distinct Senescence-Associated Secretory Phenotype in Melanoma
Authors: L Homann, M Rentschler, E Brenner, K Böhm, M Röcken, T Wieder
Cells, 2022-04-30;11(9):. 2022-04-30
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Identification of a retinoic acid-dependent haemogenic endothelial progenitor from human pluripotent stem cells
Authors: SA Luff, JP Creamer, S Valsoni, C Dege, R Scarfò, A Dacunto, S Cascione, LN Randolph, E Cavalca, I Merelli, SA Morris, A Ditadi, CM Sturgeon
Nature Cell Biology, 2022-04-28;0(0):. 2022-04-28
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At Embryo Implantation Site IL-35 Secreted by Trophoblast, Polarizing T Cells towards IL-35+ IL-10+ IL-4+ Th2-Type Cells, Could Favour Fetal Allograft Tolerance and Pregnancy Success
Authors: L Lombardell, F Logiodice, O Kullolli, H Haller, C Agostinis, R Bulla, D Rukavina, MP Piccinni
International Journal of Molecular Sciences, 2022-04-28;23(9):. 2022-04-28
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Endothelial inflammation and neutrophil transmigration are modulated by extracellular matrix composition in an inflammation-on-a-chip model
Authors: RB Riddle, K Jennbacken, KM Hansson, MT Harper
Scientific Reports, 2022-04-27;12(1):6855. 2022-04-27
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Localization and RNA Interference-Driven Inhibition of a Brugia malayi-Encoded Interleukin-5 Receptor Binding Protein
Authors: R Mejia, S Bennuru, Y Oksov, S Lustigman, G Munirathin, R Kalyanasun, TB Nutman
Infection and Immunity, 2022-04-25;0(0):e0031721. 2022-04-25
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Anti-Inflammatory and Anti-Fibrotic Effect of Immortalized Mesenchymal-Stem-Cell-Derived Conditioned Medium on Human Lung Myofibroblasts and Epithelial Cells
Authors: E Filidou, L Kandilogia, G Tarapatzi, M Spathakis, P Steiropoul, D Mikroulis, K Arvanitidi, V Paspaliari, G Kolios
International Journal of Molecular Sciences, 2022-04-20;23(9):. 2022-04-20
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Differential effects of macrophage subtypes on SARS-CoV-2 infection in a human pluripotent stem cell-derived model
Authors: Q Lian, K Zhang, Z Zhang, F Duan, L Guo, W Luo, BW Mok, A Thakur, X Ke, P Motallebne, V Nicolaescu, J Chen, CY Ma, X Zhou, S Han, T Han, W Zhang, AY Tan, T Zhang, X Wang, D Xu, J Xiang, A Xu, C Liao, FP Huang, YW Chen, J Na, G Randall, HF Tse, Z Chen, Y Chen, HJ Chen
Nature Communications, 2022-04-19;13(1):2028. 2022-04-19
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Aortic Fibrosis in Insulin-Sensitive Mice with Endothelial Cell-Specific Deletion of Ceacam1 Gene
Authors: R Abu Helal, HT Muturi, AD Lee, W Li, HE Ghadieh, SM Najjar
International Journal of Molecular Sciences, 2022-04-14;23(8):. 2022-04-14
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Mapping human haematopoietic stem cells from haemogenic endothelium to birth
Authors: V Calvanese, S Capellera-, F Ma, I Fares, S Liebscher, ES Ng, S Ekstrand, J Aguadé-Gor, A Vavilina, D Lefaudeux, B Nadel, JY Li, Y Wang, LK Lee, R Ardehali, ML Iruela-Ari, M Pellegrini, EG Stanley, AG Elefanty, K Schenke-La, HKA Mikkola
Nature, 2022-04-13;604(7906):534-540. 2022-04-13
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In Vitro Angiogenesis Inhibition and Endothelial Cell Growth and Morphology
Authors: A Ljoki, T Aslam, T Friis, RG Ohm, G Houen
International Journal of Molecular Sciences, 2022-04-12;23(8):. 2022-04-12
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The ZZ domain of HERC2 is a receptor of arginylated substrates
Authors: AH Tencer, J Liu, J Zhu, NT Burkholder, Y Zhang, W Wu, BD Strahl, T Ohta, TG Kutateladz
Scientific Reports, 2022-04-11;12(1):6063. 2022-04-11
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Adenosine inhibits TNFalpha-induced MMP-3 production in MH7A rheumatoid arthritis synoviocytes via A2A receptor signaling
Authors: H Konishi, SE Kanou, R Yukimatsu, M Inui, M Sato, N Yamamoto, M Nakano, M Koshiba
Scientific Reports, 2022-04-11;12(1):6033. 2022-04-11
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Mycobacterium avium-intracellulare complex promote release of pro-inflammatory enzymes matrix metalloproteinases by inducing neutrophil extracellular trap formation
Authors: K Nakamura, H Nakayama, S Sasaki, K Takahashi, K Iwabuchi
Scientific Reports, 2022-04-11;12(1):5181. 2022-04-11
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Mechanosensitive Piezo1 channels mediate renal fibrosis
Authors: X Zhao, Y Kong, B Liang, J Xu, Y Lin, N Zhou, J Li, B Jiang, J Cheng, C Li, W Wang
JCI Insight, 2022-04-08;0(0):. 2022-04-08
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Delivery of CAR-T cells in a transient injectable stimulatory hydrogel niche improves treatment of solid tumors
Authors: AK Grosskopf, L Labanieh, DD Klysz, GA Roth, P Xu, O Adebowale, EC Gale, CK Jons, JH Klich, J Yan, CL Maikawa, S Correa, BS Ou, AI d'Aquino, JR Cochran, O Chaudhuri, CL Mackall, EA Appel
Science Advances, 2022-04-08;8(14):eabn8264. 2022-04-08
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Dysregulated RNA polyadenylation contributes to metabolic impairment in non-alcoholic fatty liver disease
Authors: AM Jobbins, N Haberman, N Artigas, C Amourda, HAB Paterson, S Yu, SJI Blackford, A Montoya, M Dore, YF Wang, A Sardini, I Cebola, J Zuber, ST Rashid, B Lenhard, S Vernia
Nucleic Acids Research, 2022-04-08;0(0):. 2022-04-08
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Decellularized Organ-Derived Scaffold Is a Promising Carrier for Human Induced Pluripotent Stem Cells-Derived Hepatocytes
Authors: H Kojima, H Yagi, H Kushige, Y Toda, K Takayama, S Masuda, T Morisaku, T Tsuchida, K Kuroda, K Hirukawa, J Inui, K Nishi, Y Nakano, M Tanaka, S Hori, Y Hasegawa, Y Abe, M Kitago, S Adachi, M Tomi, K Matsuura, H Mizuguchi, Y Kitagawa
Cells, 2022-04-07;11(8):. 2022-04-07
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CXCL12/CXCR4-Rac1-mediated migration of osteogenic precursor cells contributes to pathological new bone formation in ankylosing spondylitis
Authors: H Cui, Z Li, S Chen, X Li, D Chen, J Wang, Z Li, W Hao, F Zhong, K Zhang, Z Zheng, Z Zhan, H Liu
Science Advances, 2022-04-06;8(14):eabl8054. 2022-04-06
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Citrullination of glucokinase is linked to autoimmune diabetes
Authors: ML Yang, S Horstman, R Gee, P Guyer, TT Lam, J Kanyo, AL Perdigoto, C Speake, CJ Greenbaum, A Callebaut, L Overbergh, RG Kibbey, KC Herold, EA James, MJ Mamula
Nature Communications, 2022-04-06;13(1):1870. 2022-04-06
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Regulation of p27 (Kip1) by Ubiquitin E3 Ligase RNF6
Authors: D Deshmukh, J Xu, X Yang, H Shimelis, S Fang, Y Qiu
Pharmaceutics, 2022-04-06;14(4):. 2022-04-06
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Combining adoptive NK cell infusion with a dopamine-releasing peptide reduces senescent cells in aged mice
Authors: Z Bai, P Yang, F Yu, Z Li, Z Yao, J Martinez, M Li, H Xu
Cell Death & Disease, 2022-04-05;13(4):305. 2022-04-05
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TET-mediated DNA hydroxymethylation is negatively influenced by the PARP-dependent PARylation
Authors: A Toli?, M Ravichandr, J Raji?, M ?or?evi?, M ?or?evi?, S Dini?, N Grdovi?, JA Jovanovi?, M Mihailovi?, N Nestorovi?, TP Jurkowski, AS Uskokovi?, MS Vidakovi?
Epigenetics & Chromatin, 2022-04-05;15(1):11. 2022-04-05
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Altered IgG glycosylation at COVID-19 diagnosis predicts disease severity
Authors: MM Vicente, I Alves, J Gaifem, CS Rodrigues, Â Fernandes, AM Dias, J Štambuk, T Petrovi?, P Oliveira, F Ferreira-d, A Soares, N Seixas, T Teixeira, L Malheiro, MM Abreu, G Lauc, R Sarmento E, SS Pinho
European Journal of Immunology, 2022-04-04;0(0):. 2022-04-04
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Mitochondria-targeted supramolecular coordination container encapsulated with exogenous itaconate for synergistic therapy of joint inflammation
Authors: X Chen, C Li, X Cao, X Jia, X Chen, Z Wang, W Xu, F Dai, S Zhang
Theranostics, 2022-04-04;12(7):3251-3272. 2022-04-04
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Exercised accelerated the production of muscle-derived kynurenic acid in skeletal muscle and alleviated the postmenopausal osteoporosis through the Gpr35/NFkappaB p65 pathway
Authors: T Shi, Y Shi, H Gao, Y Ma, Q Wang, S Shen, X Shao, W Gong, X Chen, J Qin, J Wu, Q Jiang, B Xue
Journal of Orthopaedic Translation, 2022-04-04;35(0):1-12. 2022-04-04
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PI3Kgamma stimulates a high molecular weight form of myosin light chain kinase to promote myeloid cell adhesion and tumor inflammation
Authors: MC Schmid, SW Kang, H Chen, M Paradise, A Ghebremedh, MM Kaneda, SM Chin, A Do, DM Watterson, JA Varner
Nature Communications, 2022-04-01;13(1):1768. 2022-04-01
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RBMS1 promotes gastric cancer metastasis through autocrine IL-6/JAK2/STAT3 signaling
Authors: M Liu, H Li, H Zhang, H Zhou, T Jiao, M Feng, F Na, M Sun, M Zhao, L Xue, L Xu
Cell Death & Disease, 2022-03-31;13(3):287. 2022-03-31
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Variable susceptibility of intestinal organoid-derived monolayers to SARS-CoV-2 infection
Authors: KK Jang, ME Kaczmarek, S Dallari, YH Chen, T Tada, J Axelrad, NR Landau, KA Stapleford, K Cadwell
PloS Biology, 2022-03-31;20(3):e3001592. 2022-03-31
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Tissue extracellular matrix hydrogels as alternatives to Matrigel for culturing gastrointestinal organoids
Authors: S Kim, S Min, YS Choi, SH Jo, JH Jung, K Han, J Kim, S An, YW Ji, YG Kim, SW Cho
Nature Communications, 2022-03-30;13(1):1692. 2022-03-30
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A Comparison of Evans Blue and 4-(p-Iodophenyl)butyryl Albumin Binding Moieties on an Integrin alphavbeta6 Binding Peptide
Authors: RA Davis, SH Hausner, R Harris, JL Sutcliffe
Pharmaceutics, 2022-03-30;14(4):. 2022-03-30
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SARS-CoV-2 Infects Human ACE2-Negative Endothelial Cells through an alphavbeta3 Integrin-Mediated Endocytosis Even in the Presence of Vaccine-Elicited Neutralizing Antibodies
Authors: A Bugatti, F Filippini, M Bardelli, A Zani, P Chiodelli, S Messali, A Caruso, F Caccuri
Viruses, 2022-03-29;14(4):. 2022-03-29
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Paeoniflorin attenuates monocrotaline-induced pulmonary arterial hypertension in rats by suppressing TAK1-MAPK/NF-kappaB pathways
Authors: M Yu, X Wu, J Wang, M He, H Han, S Hu, J Xu, M Yang, Q Tan, Y Wang, H Wang, W Xie, H Kong
International Journal of Medical Sciences, 2022-03-28;19(4):681-694. 2022-03-28
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Generation of a human induced pluripotent stem cell line KUMi006 from a patient with multiple myeloma
Authors: JH Hong, JH Kim, KW Kang, BH Lee, Y Park, BS Kim
Stem Cell Research, 2022-03-28;61(0):102767. 2022-03-28
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In vitro culture at 39��C during hepatic maturation of human ES cells facilitates hepatocyte-like cell functions
Authors: S Imamura, K Yoshimoto, S Terada, K Takamuro, KI Kamei
Scientific Reports, 2022-03-25;12(1):5155. 2022-03-25
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Anti-angiogenic properties of rapamycin on human retinal pericytes in an in vitro model of neovascular AMD via inhibition of the mTOR pathway
Authors: B Asani, J Siedlecki, C Wertheimer, R Liegl, A Wolf, A Ohlmann, S Priglinger, C Priglinger
BMC ophthalmology, 2022-03-25;22(1):138. 2022-03-25
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Structural dynamics of receptor recognition and pH-induced dissociation of full-length Clostridioides difficile Toxin B
Authors: M Jiang, J Shin, R Simeon, JY Chang, R Meng, Y Wang, O Shinde, P Li, Z Chen, J Zhang
PloS Biology, 2022-03-24;20(3):e3001589. 2022-03-24
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SARS-CoV-2 infects and replicates in photoreceptor and retinal ganglion cells of human retinal organoids
Authors: Y Menuchin-L, A Schreiber, A Lecanda, A Mecate-Zam, L Brunotte, OE Psathaki, S Ludwig, T Rauen, HR Schöler
Stem Cell Reports, 2022-03-24;0(0):. 2022-03-24
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Nigratine as dual inhibitor of necroptosis and ferroptosis regulated cell death
Authors: C Delehouzé, A Comte, SA Leon-Icaza, C Cougoule, M Hauteville, P Goekjian, JC Bulinski, MT Dimanche-B, E Meunier, M Rousselot, S Bach
Scientific Reports, 2022-03-24;12(1):5118. 2022-03-24
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Elimination of Reprogramming Transgenes Facilitates the Differentiation of Induced Pluripotent Stem Cells into Hepatocyte-like Cells and Hepatic Organoids
Authors: J Jeong, TH Kim, M Kim, YK Jung, KS Kim, S Shim, H Jang, WI Jang, SB Lee, D Choi
Biology, 2022-03-23;11(4):. 2022-03-23
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Biomimetic hydrogel supports initiation and growth of patient-derived breast tumor organoids
Authors: E Prince, J Cruickshan, W Ba-Alawi, K Hodgson, J Haight, C Tobin, A Wakeman, A Avoulov, V Topolskaia, MJ Elliott, AP McGuigan, HK Berman, B Haibe-Kain, DW Cescon, E Kumacheva
Nature Communications, 2022-03-18;13(1):1466. 2022-03-18
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Oxidative Stress and Antioxidant Response in Populations of the Czech Republic Exposed to Various Levels of Environmental Pollutants
Authors: A Ambroz, P Rossner, A Rossnerova, K Honkova, A Milcova, A Pastorkova, J Klema, J Pulkrabova, O Parizek, V Vondraskov, J Zelenka, N Vrzá?ková, J Schmuczero, J Topinka, RJ Sram
International Journal of Environmental Research and Public Health, 2022-03-18;19(6):. 2022-03-18
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Characterization and reduction of non-endocrine cells accompanying islet-like endocrine cells differentiated from human iPSC
Authors: H Hiyoshi, K Sakuma, N Tsubooka-Y, S Asano, T Mochida, J Yamaura, S Konagaya, R Fujii, H Matsumoto, R Ito, T Toyoda
Scientific Reports, 2022-03-18;12(1):4740. 2022-03-18
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Erucin inhibits osteoclast formation via suppressing cell-cell fusion molecule DC-STAMP without influencing mineralization by osteoblasts
Authors: T Takagi, H Inoue, S Fujii, N Takahashi, M Uehara
Bmc Research Notes, 2022-03-16;15(1):105. 2022-03-16
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The Roles of Extracellular Vesicles and Organoid Models in Female Reproductive Physiology
Authors: RE Thompson, GJ Bouma, FK Hollinshea
International Journal of Molecular Sciences, 2022-03-16;23(6):. 2022-03-16
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A Novel 3D Culture System Using a Chitin-Based Polysaccharide Material Produces High-Quality Allogeneic Human UCMSCs with Dispersed Sphere Morphology
Authors: K Kida, T Kanaki, S Gao, D Hatanaka, M Iwakami, S Liu, M Horikawa, M Ono, D Chang
Cells, 2022-03-15;11(6):. 2022-03-15
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Malfunction of airway basal stem cells plays a crucial role in pathophysiology of tracheobronchopathia osteoplastica
Authors: Y Hong, S Shan, Y Gu, H Huang, Q Zhang, Y Han, Y Dong, Z Liu, M Huang, T Ren
Nature Communications, 2022-03-14;13(1):1309. 2022-03-14
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The arginine methyltransferase PRMT7 promotes extravasation of monocytes resulting in tissue injury in COPD
Authors: G Günes Güns, TM Conlon, A Jeridi, R Kim, Z Ertüz, NJ Lang, M Ansari, M Novikova, D Jiang, M Strunz, M Gaianova, C Hollauer, C Gabriel, I Angelidis, S Doll, JC Pestoni, SL Edelmann, MS Kohlhepp, A Guillot, K Bassler, HP Van Eeckho, Ö Kayalar, N Konyalilar, T Kanashova, S Rodius, C Ballester-, CM Genes Robl, N Smirnova, M Rehberg, C Agarwal, I Krikki, B Piavaux, SE Verleden, B Vanaudenae, M Königshoff, G Dittmar, KR Bracke, JL Schultze, H Watz, O Eickelberg, T Stoeger, G Burgstalle, F Tacke, V Heissmeyer, Y Rinkevich, H Bayram, HB Schiller, M Conrad, R Schneider, AÖ Yildirim
Nature Communications, 2022-03-14;13(1):1303. 2022-03-14
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MicroRNA-22 represses glioma development via activation of macrophage-mediated innate and adaptive immune responses
Authors: J Tu, Y Fang, D Han, X Tan, Z Xu, H Jiang, X Wang, W Hong, W Wei
Oncogene, 2022-03-12;0(0):. 2022-03-12
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Generation of an induced pluripotent stem cell (iPSC) line from a diabetic patient with glucagon receptor (GCGR) p.W83X mutation
Authors: Y Liu, Y Liu, Y Jia, J Lv, D Sun, Y Yin, N Liu, B Su, G Sun
Stem Cell Research, 2022-03-11;61(0):102745. 2022-03-11
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Human C1q Regulates Influenza A Virus Infection and Inflammatory Response via Its Globular Domain
Authors: PM Varghese, U Kishore, R Rajkumari
International Journal of Molecular Sciences, 2022-03-11;23(6):. 2022-03-11
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MESH1 knockdown triggers proliferation arrest through TAZ repression
Authors: T Sun, CC Ding, Y Zhang, Y Zhang, CC Lin, J Wu, Y Setayeshpo, S Coggins, C Shepard, E Macias, B Kim, P Zhou, R Gordân, JT Chi
Cell Death & Disease, 2022-03-10;13(3):221. 2022-03-10
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The non-ELR CXC chemokine encoded by human cytomegalovirus UL146 genotype 5 contains a C-terminal beta-hairpin and induces neutrophil migration as a selective CXCR2 agonist
Authors: C Berg, MJ Wedemeyer, M Melynis, RR Schlimgen, LH Hansen, J Våbenø, FC Peterson, BF Volkman, MM Rosenkilde, HR Lüttichau
PloS Pathogens, 2022-03-10;18(3):e1010355. 2022-03-10
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Targeting IL-36 improves age-related coronary microcirculatory dysfunction and attenuates myocardial ischaemia-reperfusion injury in mice
Authors: J El-Awaisi, DP Kavanagh, MR Rink, CJ Weston, NE Drury, N Kalia
JCI Insight, 2022-03-08;0(0):. 2022-03-08
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Inhibition of myeloid PD-L1 suppresses osteoclastogenesis and cancer bone metastasis
Authors: H Zuo, Y Wan
Cancer Gene Therapy, 2022-03-07;0(0):. 2022-03-07
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Reticulocyte Maturation and Variant Red Blood Cells
Authors: CJ Stevens-He, JF Flatt, S Kupzig, LJ Bruce
Frontiers in Physiology, 2022-03-07;13(0):834463. 2022-03-07
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Melatonin reverses tumor necrosis factor-alpha-induced metabolic disturbance of human nucleus pulposus cells via MTNR1B/Galphai2/YAP signaling
Authors: X Qiu, T Liang, Z Wu, Y Zhu, W Gao, B Gao, J Qiu, X Wang, T Chen, Z Deng, P Li, Y Chen, H Zhou, Y Peng, C Xu, P Su, A Liang, D Huang
International journal of biological sciences, 2022-03-06;18(5):2202-2219. 2022-03-06
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DRG2 Depletion Promotes Endothelial Cell Senescence and Vascular Endothelial Dysfunction
Authors: AN Le, SS Park, MX Le, UH Lee, BK Ko, HR Lim, R Yu, SH Choi, BJ Lee, SY Ham, CM Ha, JW Park
International Journal of Molecular Sciences, 2022-03-06;23(5):. 2022-03-06
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Specific mesoderm subset derived from human pluripotent stem cells ameliorates microvascular pathology in type 2 diabetic mice
Authors: CH Gil, D Chakrabort, CP Vieira, N Prasain, SL Calzi, SD Fortmann, P Hu, K Banno, M Jamal, C Huang, MS Sielski, Y Lin, X Huang, MD Dupont, JL Floyd, R Prasad, ALF Longhini, TJ McGill, HM Chung, MP Murphy, DN Kotton, ME Boulton, MC Yoder, MB Grant
Science Advances, 2022-03-04;8(9):eabm5559. 2022-03-04
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Mitochondrial pyruvate carrier blockade results in decreased osteoclastogenesis and bone resorption via regulating mitochondrial energy production
Authors: Q Guo, H Zhao, H Cheng, H Kang, Y Dong, R Peng, M Zhu, Z Fang, F Li
The Journal of Biological Chemistry, 2022-03-04;0(0):101775. 2022-03-04
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Immunoregulatory effects of Lactococcus lactis-derived extracellular vesicles in allergic asthma
Authors: DH Lee, HK Park, HR Lee, H Sohn, S Sim, HJ Park, YS Shin, YK Kim, Y Choi, HS Park
Clinical and translational allergy, 2022-03-01;12(3):e12138. 2022-03-01
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Tumor RNA transfected DCs derived from iPS cells elicit cytotoxicity against cancer cells induced from colorectal cancer patients in vitro
Authors: S Maruoka, T Ojima, H Iwamoto, J Kitadani, H Tabata, S Tominaga, M Katsuda, K Hayata, A Takeuchi, H Yamaue
Scientific Reports, 2022-02-28;12(1):3295. 2022-02-28
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Mineralizing Gelatin Microparticles as Cell Carrier and Drug Delivery System for siRNA for Bone Tissue Engineering
Authors: S Hinkelmann, AH Springwald, S Schulze, U Hempel, F Mitrach, C Wölk, MC Hacker, M Schulz-Sie
Pharmaceutics, 2022-02-28;14(3):. 2022-02-28
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Effects and Mechanisms of Rhus chinensis Mill. Fruits on Suppressing RANKL-Induced Osteoclastogenesis by Network Pharmacology and Validation in RAW264.7 Cells
Authors: Y Zheng, L Zhao, J Yi, S Cai
Nutrients, 2022-02-28;14(5):. 2022-02-28
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Potential of a Novel Chemical Compound Targeting Matrix Metalloprotease-13 for Early Osteoarthritis: An In Vitro Study
Authors: J Inagaki, A Nakano, OF Hatipoglu, Y Ooka, Y Tani, A Miki, K Ikemura, G Opoku, R Ando, S Kodama, T Ohtsuki, H Yamaji, S Yamamoto, E Katsuyama, S Watanabe, S Hirohata
International Journal of Molecular Sciences, 2022-02-28;23(5):. 2022-02-28
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Plumbagin is a NF-kappaB-Inducing Kinase Inhibitor with Dual Anabolic and Anti-Resorptive Effects that Prevents Menopausal-Related Osteoporosis in Mice
Authors: G Shen, X Liu, W Lei, R Duan, Z Yao
The Journal of Biological Chemistry, 2022-02-27;0(0):101767. 2022-02-27
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Histone Deacetylase Inhibitors Downregulate Calcium Pyrophosphate Crystal Formation in Human Articular Chondrocytes
Authors: CC Chang, KL Lee, TS Chan, CC Chung, YC Liang
International Journal of Molecular Sciences, 2022-02-26;23(5):. 2022-02-26
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Ultraefficient extracellular vesicle-guided direct reprogramming of fibroblasts into functional cardiomyocytes
Authors: H Kim, BW Song, SJ Park, SW Choi, H Moon, KC Hwang, SW Kang, SH Moon, Y Yang, IC Kwon, SH Kim
Science Advances, 2022-02-25;8(8):eabj6621. 2022-02-25
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Metastatic Tumor Cell-Specific FABP7 Promotes NSCLC Metastasis via Inhibiting beta-Catenin Degradation
Authors: Q Bai, X Yang, Q Li, W Chen, H Tian, R Lian, X Liu, S Wang, Y Yang
Cells, 2022-02-25;11(5):. 2022-02-25
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Biological Effects of Cyclin-Dependent Kinase Inhibitors Ribociclib, Palbociclib and Abemaciclib on Breast Cancer Bone Microenvironment
Authors: M Iuliani, S Simonetti, G Ribelli, A Napolitano, UG Longo, B Vincenzi, P Orsaria, V Denaro, G Tonini, D Santini, P Francesco
International Journal of Molecular Sciences, 2022-02-24;23(5):. 2022-02-24
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Interleukin-17 promotes osteoclastogenesis and periodontal damage via autophagy in vitro and in vivo
Authors: J Zhong, Z Wang, W Yuan, Y Shen, L Chen
International immunopharmacology, 2022-02-23;107(0):108631. 2022-02-23
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Fibrotic lung disease inhibits innate immune responses to Staphylococcal pneumonia via impaired neutrophil and macrophage function
Authors: HI Warheit-Ni, SJ Edwards, S SenGupta, CA Parent, X Zhou, DN O'Dwyer, BB Moore
JCI Insight, 2022-02-22;0(0):. 2022-02-22
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Superantigens promote Staphylococcus aureus bloodstream infection by eliciting pathogenic interferon-gamma production
Authors: SW Tuffs, MI Goncheva, SX Xu, HC Craig, KJ Kasper, J Choi, RS Flannagan, SM Kerfoot, DE Heinrichs, JK McCormick
Proceedings of the National Academy of Sciences of the United States of America, 2022-02-22;119(8):. 2022-02-22
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Pro- and Anti-Inflammatory Cytokines in the Context of NK Cell-Trophoblast Interactions
Authors: V Mikhailova, P Grebenkina, E Khokhlova, A Davydova, Z Salloum, E Tyshchuk, V Zagainova, K Markova, I Kogan, S Selkov, D Sokolov
International Journal of Molecular Sciences, 2022-02-21;23(4):. 2022-02-21
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Engineered Zinc Finger Protein Targeting 2LTR Inhibits HIV Integration in Hematopoietic Stem and Progenitor Cell-Derived Macrophages: In Vitro Study
Authors: K Chupradit, W Khamaikawi, S Sakkhachor, C Puaninta, BE Torbett, S Borwornpin, S Hongeng, M Wattanapan, C Tayapiwata
International Journal of Molecular Sciences, 2022-02-19;23(4):. 2022-02-19
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Interplay between nuclear factor-kappaB, p38 MAPK and glucocorticoid receptor signaling synergistically induces functional TLR2 in lung epithelial cells
Authors: A Bansal, MM Mostafa, C Kooi, SK Sasse, AN Michi, SV Shah, R Leigh, AN Gerber, R Newton
The Journal of Biological Chemistry, 2022-02-19;0(0):101747. 2022-02-19
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Antibody-Drug Conjugate Targeting c-Kit for the Treatment of Small Cell Lung Cancer
Authors: KH Kim, JO Kim, JY Park, MD Seo, SG Park
International Journal of Molecular Sciences, 2022-02-18;23(4):. 2022-02-18
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Vitamin D3 Stimulates Proliferation Capacity, Expression of Pluripotency Markers, and Osteogenesis of Human Bone Marrow Mesenchymal Stromal/Stem Cells, Partly through SIRT1 Signaling
Authors: A Borojevi?, A Jaukovi?, T Kukolj, S Mojsilovi?, H Obradovi?, D Trivanovi?, M Živanovi?, Ž Ze?evi?, M Simi?, B Gobelji?, D Vuji?, D Bugarski
Biomolecules, 2022-02-18;12(2):. 2022-02-18
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Biological Characterization of Yellow Fever Viruses Isolated From Non-human Primates in Brazil With Distinct Genomic Landscapes
Authors: ND Furtado, LM Raphael, IP Ribeiro, IS de Mello, DR Fernandes, MM Gómez, AAC Dos Santos, MDS Nogueira, MG de Castro, FVS de Abreu, LC Martins, PFDC Vasconcelo, R Lourenço-d, MC Bonaldo
Frontiers in Microbiology, 2022-02-14;13(0):757084. 2022-02-14
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Development of Surgically Transplantable Parathyroid Hormone-Releasing Microbeads
Authors: HY Kim, JM Seok, SY Jung, MJ Lee, AN Tran, SJ Yeo, SA Park, HS Kim
Biomedicines, 2022-02-14;10(2):. 2022-02-14
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Chemokine (C-C Motif) Ligand 8 and Tubulo-Interstitial Injury in Chronic Kidney Disease
Authors: J Lee, Y Lee, KH Kim, DK Kim, KW Joo, SJ Shin, YS Kim, SH Yang
Cells, 2022-02-14;11(4):. 2022-02-14
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Oxidative Stress Enhances the TGF-beta2-RhoA-MRTF-A/B Axis in Cells Entering Endothelial-Mesenchymal Transition
Authors: K Sobierajsk, ME Wawro, J Niewiarows
International Journal of Molecular Sciences, 2022-02-13;23(4):. 2022-02-13
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Miconazole Mitigates Acetic Acid-Induced Experimental Colitis in Rats: Insight into Inflammation, Oxidative Stress and Keap1/Nrf-2 Signaling Crosstalk
Authors: IA Alsharif, HM Fayed, RF Abdel-Rahm, RM Abd-Elsala, HA Ogaly
Biology, 2022-02-13;11(2):. 2022-02-13
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A new hemostatic agent composed of Zn2+-enriched Ca2+ alginate activates vascular endothelial cells in vitro and promotes tissue repair in vivo
Authors: AC Ponsen, R Proust, S Soave, F Mercier-No, I Garcin, L Combettes, JJ Lataillade, G Uzan
Bioactive materials, 2022-02-12;18(0):368-382. 2022-02-12
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Development of a skin- and neuro-attenuated live vaccine for varicella
Authors: W Wang, D Pan, W Fu, X Ye, J Han, L Yang, J Jia, J Liu, R Zhu, Y Zhang, C Liu, J Ye, A Selariu, Y Que, Q Zhao, T Wu, Y Li, J Zhang, T Cheng, H Zhu, N Xia
Nature Communications, 2022-02-11;13(1):824. 2022-02-11
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CERS6-AS1 contributes to the malignant phenotypes of colorectal cancer cells by interacting with miR-15b-5p to regulate SPTBN2
Authors: SY Zhao, Z Wang, XB Wu, S Zhang, Q Chen, DD Wang, QF Tan
The Kaohsiung journal of medical sciences, 2022-02-11;0(0):. 2022-02-11
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GM-CSF perturbs cell identity in mouse pre-implantation embryos
Authors: T Pock, K Schulte, S Schlatt, M Boiani, V Nordhoff
PLoS ONE, 2022-02-10;17(2):e0263793. 2022-02-10
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PD-1 agonism by anti-CD80 inhibits T cell activation and alleviates autoimmunity
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Nature Immunology, 2022-02-10;0(0):. 2022-02-10
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Two distinct classes of co-chaperones compete for the EEVD motif in heat shock protein 70 (Hsp70) to tune its chaperone activities
Authors: OT Johnson, CM Nadel, EC Carroll, T Arhar, JE Gestwicki
The Journal of Biological Chemistry, 2022-02-09;0(0):101697. 2022-02-09
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Modeling axonal regeneration by changing cytoskeletal dynamics in stem cell-derived motor nerve organoids
Authors: WM Seo, J Yoon, JH Lee, Y Lee, H Lee, D Geum, W Sun, MR Song
Scientific Reports, 2022-02-08;12(1):2082. 2022-02-08
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Effects of IFNgamma and IL4 rich microenvironment on porcine monocyte-derived dendritic cell activation in vitro
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Research in Veterinary Science, 2022-02-06;145(0):54-62. 2022-02-06
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Heparin-Functionalized Adsorbents Eliminate Central Effectors of Immunothrombosis, including Platelet Factor 4, High-Mobility Group Box 1 Protein and Histones
Authors: M Ebeyer-Mas, T Eichhorn, R Weiss, V Semak, L Lauková, MB Fischer, V Weber
International Journal of Molecular Sciences, 2022-02-05;23(3):. 2022-02-05
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Ionic mitigation of CD4+ T cell metabolic fitness, Th1 central nervous system autoimmunity and Th2 asthmatic airway inflammation by therapeutic zinc
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Scientific Reports, 2022-02-04;12(1):1943. 2022-02-04
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Induction of Pro-Fibrotic CLIC4 in Dermal Fibroblasts by TGF-beta/Wnt3a Is Mediated by GLI2 Upregulation
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Cells, 2022-02-03;11(3):. 2022-02-03
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Leveraging interacting signaling pathways to robustly improve the quality and yield of human pluripotent stem cell-derived hepatoblasts and hepatocytes
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Stem Cell Reports, 2022-02-03;0(0):. 2022-02-03
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3D Printed Graphene-PLA Scaffolds Promote Cell Alignment and Differentiation
Authors: M Gasparotto, P Bellet, G Scapin, R Busetto, C Rampazzo, L Vitiello, DI Shah, F Filippini
International Journal of Molecular Sciences, 2022-02-03;23(3):. 2022-02-03
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Verteporfin-mediated on/off photoswitching functions synergistically to treat choroidal vascular diseases
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Bioactive materials, 2022-02-01;14(0):402-415. 2022-02-01
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Gene silencing by EZH2 suppresses TGF-beta activity within the decidua to avert pregnancy-adverse wound healing at the maternal-fetal interface
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Cell Reports, 2022-02-01;38(5):110329. 2022-02-01
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Fucoidan Isolated from Sargassum confusum Suppresses Inflammatory Responses and Oxidative Stress in TNF-alpha/IFN-gamma- Stimulated HaCaT Keratinocytes by Activating Nrf2/HO-1 Signaling Pathway
Authors: AMK Jayasinghe, KGIS Kirindage, IPS Fernando, EJ Han, GW Oh, WK Jung, G Ahn
Marine Drugs, 2022-02-01;20(2):. 2022-02-01
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Spexin Regulates Hypothalamic Leptin Action on Feeding Behavior
Authors: B Jeong, KK Kim, TH Lee, HR Kim, BS Park, JW Park, JK Jeong, JY Seong, BJ Lee
Biomolecules, 2022-01-31;12(2):. 2022-01-31
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Single-cell transcriptomic analysis reveals a novel cell state�and switching genes during hepatic stellate cell activation in vitro
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Journal of Translational Medicine, 2022-01-29;20(1):53. 2022-01-29
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Extracellular Vesicles Derived from Primed Mesenchymal Stromal Cells Loaded on Biphasic Calcium Phosphate Biomaterial Exhibit Enhanced Macrophage Polarization
Authors: N Rana, S Suliman, N Al-Sharabi, K Mustafa
Cells, 2022-01-29;11(3):. 2022-01-29
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Pleiotropic, Unique and Shared Responses Elicited by IL-6 Family Cytokines in Human Vascular Endothelial Cells
Authors: M Lindkvist, MM Zegeye, M Grenegård, LU Ljungberg
International Journal of Molecular Sciences, 2022-01-27;23(3):. 2022-01-27
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Nuclear IL-33 regulates cytokinesis and cell motility in normal human epidermal keratinocytes
Authors: H Tsuda, SI Tominaga, M Ohtsuki, M Komine
Journal of dermatological science, 2022-01-25;0(0):. 2022-01-25
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Neuropilin-1 mediates lung tissue-specific control of ILC2 function in type 2 immunity
Authors: J Zhang, J Qiu, W Zhou, J Cao, X Hu, W Mi, B Su, B He, J Qiu, L Shen
Nature Immunology, 2022-01-24;0(0):. 2022-01-24
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miR-29b inhibits TGF-beta1-induced cell proliferation in articular chondrocytes
Authors: M Horita, SN Hsu, A Raper, C Farquharso, LA Stephen
Biochemistry and Biophysics Reports, 2022-01-24;29(0):101216. 2022-01-24
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A kainic acid-induced seizure model in human pluripotent stem cell-derived cortical neurons for studying the role of IL-6 in the functional activity
Authors: R Mzezewa, J Lotila, H Kiiski, A Vinogradov, FE Kapucu, J Peltola, S Hagman, S Narkilahti
Stem Cell Research, 2022-01-17;60(0):102665. 2022-01-17
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Irgm1 regulates metabolism and function in T cell subsets
Authors: Y Alwarawrah, K Danzaki, AG Nichols, BE Fee, C Bock, G Kucera, LP Hale, GA Taylor, NJ MacIver
Scientific Reports, 2022-01-17;12(1):850. 2022-01-17
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A human pluripotent stem cell line KUMi004-A generated from a patient with chronic lymphocytic leukemia
Authors: JH Kim, KW Kang, BH Lee, Y Park, H Jung Sung, BS Kim
Stem Cell Research, 2022-01-15;60(0):102668. 2022-01-15
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Engagement of the CXCL12-CXCR4 Axis in the Interaction of Endothelial Progenitor Cell and Smooth Muscle Cell to Promote Phenotype Control and Guard Vascular Homeostasis
Authors: SF Mause, E Ritzel, A Deck, F Vogt, EA Liehn
International Journal of Molecular Sciences, 2022-01-14;23(2):. 2022-01-14
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RGMa regulates CCL5 expression via the BMP receptor in experimental autoimmune encephalomyelitis mice and endothelial cells
Authors: S Tang, B Su, T Tao, W Yan, R Zhang, X Qin, J Feng
Molecular Medicine Reports, 2022-01-14;25(3):. 2022-01-14
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Anti-GD2 synergizes with CD47 blockade to mediate tumor eradication
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Nature Medicine, 2022-01-13;0(0):. 2022-01-13
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53BP1-shieldin-dependent DSB processing in BRCA1-deficient cells requires CST-Polalpha-primase fill-in synthesis
Authors: Z Mirman, NK Sasi, A King, JR Chapman, T de Lange
Nature Cell Biology, 2022-01-13;24(1):51-61. 2022-01-13
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Impact and Possible Mechanism(s) of Adipose Tissue-Derived Mesenchymal Stem Cells on T-Cell Proliferation in Patients With Rheumatic Disease
Authors: E Kuca-Warna, M Olesi?ska, P Szcz?sny, E Kontny
Frontiers in Physiology, 2022-01-13;12(0):749481. 2022-01-13
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The Roles of IL-22 and Its Receptor in the Regulation of Inflammatory Responses in the Brain
Authors: D Lee, H Jo, C Go, Y Jang, N Chu, S Bae, D Kang, Y Kim, JS Kang
International Journal of Molecular Sciences, 2022-01-11;23(2):. 2022-01-11
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Single-cell analysis of human primary prostate cancer reveals the heterogeneity of tumor-associated epithelial cell states
Authors: H Song, HNW Weinstein, P Allegakoen, MH Wadsworth, J Xie, H Yang, EA Castro, KL Lu, BA Stohr, FY Feng, PR Carroll, B Wang, MR Cooperberg, AK Shalek, FW Huang
Nature Communications, 2022-01-10;13(1):141. 2022-01-10
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Density-Dependent Differentiation of Tonsil-Derived Mesenchymal Stem Cells into Parathyroid-Hormone-Releasing Cells
Authors: JY Kim, S Park, SY Oh, YH Nam, YM Choi, Y Choi, HY Kim, SY Jung, HS Kim, I Jo, SC Jung
International Journal of Molecular Sciences, 2022-01-10;23(2):. 2022-01-10
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Ionizing Radiation Activates Mitochondrial Function in Osteoclasts and Causes Bone Loss in Young Adult Male Mice
Authors: KK Richardson, W Ling, K Krager, Q Fu, SD Byrum, R Pathak, N Aykin-Burn, HN Kim
International Journal of Molecular Sciences, 2022-01-08;23(2):. 2022-01-08
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Deubiquitinase Inhibitors Impair Leukemic Cell Migration Through Cofilin Oxidation and Alteration of Actin Reorganization
Authors: F Larbret, P Biber, N Dubois, S Ivanov, L Lafanecher, S Tartare-De, M Deckert
Frontiers in Pharmacology, 2022-01-07;12(0):778216. 2022-01-07
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Increased Expression and Altered Cellular Localization of Fibroblast Growth Factor Receptor-Like 1 (FGFRL1) Are Associated with Prostate Cancer Progression
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Cancers, 2022-01-07;14(2):. 2022-01-07
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MiR-218 Promotes Adriamycin-Induced H9C2 Apoptosis by Inhibiting Stress-Associated Endoplasmic Reticulum Protein 1
Authors: Q Chen, G Chen, S Zhao
Disease Markers, 2022-01-04;2022(0):6881103. 2022-01-04
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The Salutary Effects of Catalpol on Diesel Exhaust Particles-Induced Thrombogenic Changes and Cardiac Oxidative Stress, Inflammation and Apoptosis
Authors: A Nemmar, S Beegam, NE Zaaba, S Alblooshi, S Alseiari, BH Ali
Biomedicines, 2022-01-04;10(1):. 2022-01-04
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A multivariate modeling framework to quantify immune checkpoint context-dependent stimulation on T cells
Authors: L Karpf, C Trichot, L Faucheux, I Legbre, M Grandclaud, C Lahoute, H Mattoo, B Pasquier, V Soumelis
Cell Discovery, 2022-01-04;8(1):1. 2022-01-04
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Elevated Serum Leptin Levels in Patients With Eosinophilic Chronic Rhinosinusitis
Authors: Y Imoto, S Ueki, Y Kato, K Yoshida, T Morikawa, Y Kimura, M Kidoguchi, T Tsutsumiuc, K Koyama, N Adachi, Y Ito, K Ogi, M Sakashita, T Yamada, RP Schleimer, T Takabayash, S Fujieda
Frontiers in Pharmacology, 2022-01-03;12(0):793607. 2022-01-03
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CTCF Expression and Dynamic Motif Accessibility Modulates Epithelial-Mesenchymal Gene Expression
Authors: KS Johnson, S Hussein, P Chakrabort, A Muruganant, S Mikhail, G Gonzalez, S Song, MK Jolly, MJ Toneff, ML Benton, YC Lin, JH Taube
Cancers, 2022-01-01;14(1):. 2022-01-01
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Intracameral Microimaging of Maturation of Human iPSC Derivatives into Islet Endocrine Cells
Authors: K Zhao, Y Shi, J Yu, L Yu, A Mael, Y Li, A Kolton, T Joyce, J Odorico, PO Berggren, SN Yang
Cell Transplantation, 2022-01-01;31(0):9636897211066. 2022-01-01
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MGE-Like Neural Progenitor Cell Survival and Expression of Parvalbumin and Proenkephalin in a Jaundiced Rat Model of Kernicterus
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Cell Transplantation, 2022-01-01;31(0):9636897221101. 2022-01-01
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GM-CSF perturbs cell identity in mouse pre-implantation embryos
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PLoS ONE, 2022;17(2):e0263793. 2022
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Retinal Pigment Epithelium-Secreted VEGF-A Induces Alpha-2-Macroglobulin Expression in Endothelial Cells
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Cells, 2022;11(19):. 2022
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53BP1-shieldin-dependent DSB processing in BRCA1-deficient cells requires CST-Polalpha-primase fill-in synthesis
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Nature Cell Biology, 2022;24(1):51-61. 2022
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The structure-selective endonucleases GEN1 and MUS81 mediate complementary functions in safeguarding the genome of proliferating B lymphocytes
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Elife, 2022;11(0):. 2022
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High Cholesterol-Induced Bone Loss Is Attenuated by Arctiin via an Action in Osteoclasts
Authors: G Li, JN Park, HJ Park, JH Suh, HS Choi
Nutrients, 2022;14(21):. 2022
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Heightened apoptotic priming of vascular cells across tissues and life span predisposes them to cancer therapy-induced toxicities
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Science Advances, 2022;8(45):eabn6579. 2022
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Localization and RNA Interference-Driven Inhibition of a Brugia malayi-Encoded Interleukin-5 Receptor Binding Protein
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Infection and Immunity, 2022;0(0):e0031721. 2022
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Anti-GD2 synergizes with CD47 blockade to mediate tumor eradication
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Nature Medicine, 2022;0(0):. 2022
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Single-cell analysis of human primary prostate cancer reveals the heterogeneity of tumor-associated epithelial cell states
Authors: H Song, HNW Weinstein, P Allegakoen, MH Wadsworth, J Xie, H Yang, EA Castro, KL Lu, BA Stohr, FY Feng, PR Carroll, B Wang, MR Cooperberg, AK Shalek, FW Huang
Nature Communications, 2022;13(1):141. 2022
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Interactions between Major Bioactive Polyphenols of Sugarcane Top: Effects on Human Neural Stem Cell Differentiation and Astrocytic Maturation
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International Journal of Molecular Sciences, 2022;23(23):. 2022
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Therapeutic effect of ibrutinib, a selective Bruton's tyrosine kinase inhibitor, in orbital fibroblasts from patients with Graves' orbitopathy
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PLoS ONE, 2022;17(12):e0279060. 2022
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Combining adoptive NK cell infusion with a dopamine-releasing peptide reduces senescent cells in aged mice
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Cell Death & Disease, 2022;13(4):305. 2022
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Neuropilin-1 mediates lung tissue-specific control of ILC2 function in type 2 immunity
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Nature Immunology, 2022;0(0):. 2022
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MaNAC029 modulates ethylene biosynthesis and fruit quality and undergoes MaXB3-mediated proteasomal degradation during banana ripening
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Journal of advanced research, 2022;0(0):. 2022
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Lipocalin 2 potentially contributes to tumorigenesis from colitis via IL-6/STAT3/NF-kB signaling pathway
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Inflammatory Cytokines That Enhance Antigen Responsiveness of Na�ve CD8+ T Lymphocytes Modulate Chromatin Accessibility of Genes Impacted by Antigen Stimulation
Authors: AJI Quenum, MA Santharam, S Ramanathan, S Ilangumara
International Journal of Molecular Sciences, 2022;23(22):. 2022
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Inhibiting ACK1-mediated phosphorylation of C-terminal Src kinase counteracts prostate cancer immune checkpoint blockade resistance
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Nature Communications, 2022;13(1):6929. 2022
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CD206<sup>+</sup>CD68<sup>+</sup> mono-macrophages and serum soluble CD206 level are increased in antineutrophil cytoplasmic antibodies associated glomerulonephritis
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BMC immunology, 2022;23(1):55. 2022
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S100A8-mediated metabolic adaptation controls HIV-1 persistence in macrophages in vivo
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Nature Communications, 2022;13(1):5956. 2022
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The Salutary Effects of Catalpol on Diesel Exhaust Particles-Induced Thrombogenic Changes and Cardiac Oxidative Stress, Inflammation and Apoptosis
Authors: A Nemmar, S Beegam, NE Zaaba, S Alblooshi, S Alseiari, BH Ali
Biomedicines, 2022;10(1):. 2022
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Generation of Functional Immortalized Human Corneal Stromal Stem Cells
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International Journal of Molecular Sciences, 2022;23(21):. 2022
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Cisplatin-induced cell death increases the degradation of the MRE11-RAD50-NBS1 complex through the autophagy/lysosomal pathway
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Protein tyrosine kinase 7 (PTK7) promotes metastasis in hepatocellular carcinoma via SOX9 regulation and TGF-beta signaling
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Immunoregulatory effects of Lactococcus lactis-derived extracellular vesicles in allergic asthma
Authors: DH Lee, HK Park, HR Lee, H Sohn, S Sim, HJ Park, YS Shin, YK Kim, Y Choi, HS Park
Clinical and translational allergy, 2022;12(3):e12138. 2022
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Tuft-cell-intrinsic and -extrinsic mediators of norovirus tropism regulate viral immunity
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Cell Reports, 2022;41(6):111593. 2022
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Bone Marrow-Derived Vasculogenic Mesenchymal Stem Cells Enhance In Vitro Angiogenic Sprouting of Human Umbilical Vein Endothelial Cells
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In Vitro Angiogenesis Inhibition and Endothelial Cell Growth and Morphology
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miR-29b inhibits TGF-beta1-induced cell proliferation in articular chondrocytes
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Biochemistry and Biophysics Reports, 2022;29(0):101216. 2022
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Visualizing inflammation with an M1 macrophage selective probe via GLUT1 as the gating target
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Nature Communications, 2022;13(1):5974. 2022
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Tumor-associated macrophages promote resistance of hepatocellular carcinoma cells against sorafenib by activating CXCR2 signaling
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Aortic Fibrosis in Insulin-Sensitive Mice with Endothelial Cell-Specific Deletion of Ceacam1 Gene
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International Journal of Molecular Sciences, 2022;23(8):. 2022
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Adenosine inhibits TNFalpha-induced MMP-3 production in MH7A rheumatoid arthritis synoviocytes via A2A receptor signaling
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Scientific Reports, 2022;12(1):6033. 2022
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Upregulation of PCED1B-AS1 in proliferative diabetic retinopathy and its involvement in retinal vascular endothelial cell proliferation
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BMC ophthalmology, 2022;22(1):450. 2022
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RBMS1 promotes gastric cancer metastasis through autocrine IL-6/JAK2/STAT3 signaling
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ST3GAL3 Promotes the Inflammatory Response of Fibroblast-Like Synoviocytes in Rheumatoid Arthritis by Activating the TLR9/MyD88 Pathway
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Mediators of Inflammation, 2022;2022(0):4258742. 2022
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American journal of cancer research, 2022;12(6):2817-2832. 2022
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Development of a Monoclonal Antibody Targeting HTLV-1 Envelope gp46 Glycoprotein and Its Application to Near-Infrared Photoimmuno-Antimicrobial Strategy
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A Novel Inhibitor INF 39 Promotes Osteogenesis via Blocking the NLRP3/IL-1beta Axis
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At Embryo Implantation Site IL-35 Secreted by Trophoblast, Polarizing T Cells towards IL-35+ IL-10+ IL-4+ Th2-Type Cells, Could Favour Fetal Allograft Tolerance and Pregnancy Success
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Exercised accelerated the production of muscle-derived kynurenic acid in skeletal muscle and alleviated the postmenopausal osteoporosis through the Gpr35/NFkappaB p65 pathway
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Scientific Reports, 2022;12(1):5155. 2022
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Ionizing Radiation Activates Mitochondrial Function in Osteoclasts and Causes Bone Loss in Young Adult Male Mice
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International Journal of Molecular Sciences, 2022;23(2):. 2022
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Altered IgG glycosylation at COVID-19 diagnosis predicts disease severity
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Effects and Mechanisms of Rhus chinensis Mill. Fruits on Suppressing RANKL-Induced Osteoclastogenesis by Network Pharmacology and Validation in RAW264.7 Cells
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Nutrients, 2022;14(5):. 2022
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Human C1q Regulates Influenza A Virus Infection and Inflammatory Response via Its Globular Domain
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International Journal of Molecular Sciences, 2022;23(6):. 2022
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Oxidative Stress and Antioxidant Response in Populations of the Czech Republic Exposed to Various Levels of Environmental Pollutants
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International Journal of Environmental Research and Public Health, 2022;19(6):. 2022
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The Roles of Extracellular Vesicles and Organoid Models in Female Reproductive Physiology
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Biomimetic hydrogel supports initiation and growth of patient-derived breast tumor organoids
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Single-cell transcriptomic analysis reveals a novel cell state�and switching genes during hepatic stellate cell activation in vitro
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Engagement of the CXCL12-CXCR4 Axis in the Interaction of Endothelial Progenitor Cell and Smooth Muscle Cell to Promote Phenotype Control and Guard Vascular Homeostasis
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The Roles of IL-22 and Its Receptor in the Regulation of Inflammatory Responses in the Brain
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International Journal of Molecular Sciences, 2022;23(2):. 2022
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Interplay between nuclear factor-kappaB, p38 MAPK and glucocorticoid receptor signaling synergistically induces functional TLR2 in lung epithelial cells
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The Journal of Biological Chemistry, 2022;0(0):101747. 2022
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Engineered Zinc Finger Protein Targeting 2LTR Inhibits HIV Integration in Hematopoietic Stem and Progenitor Cell-Derived Macrophages: In Vitro Study
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International Journal of Molecular Sciences, 2022;23(4):. 2022
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Spexin Regulates Hypothalamic Leptin Action on Feeding Behavior
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Biomolecules, 2022;12(2):. 2022
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Vitamin D3 Stimulates Proliferation Capacity, Expression of Pluripotency Markers, and Osteogenesis of Human Bone Marrow Mesenchymal Stromal/Stem Cells, Partly through SIRT1 Signaling
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Fucoidan Isolated from Sargassum confusum Suppresses Inflammatory Responses and Oxidative Stress in TNF-alpha/IFN-gamma- Stimulated HaCaT Keratinocytes by Activating Nrf2/HO-1 Signaling Pathway
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Marine Drugs, 2022;20(2):. 2022
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Nuclear IL-33 regulates cytokinesis and cell motility in normal human epidermal keratinocytes
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A human pluripotent stem cell line KUMi004-A generated from a patient with chronic lymphocytic leukemia
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Stem Cell Research, 2022;60(0):102668. 2022
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Antibody-Drug Conjugate Targeting c-Kit for the Treatment of Small Cell Lung Cancer
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International Journal of Molecular Sciences, 2022;23(4):. 2022
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RGMa regulates CCL5 expression via the BMP receptor in experimental autoimmune encephalomyelitis mice and endothelial cells
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Molecular Medicine Reports, 2022;25(3):. 2022
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Interleukin-17 promotes osteoclastogenesis and periodontal damage via autophagy in vitro and in vivo
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Heparin-Functionalized Adsorbents Eliminate Central Effectors of Immunothrombosis, including Platelet Factor 4, High-Mobility Group Box 1 Protein and Histones
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International Journal of Molecular Sciences, 2022;23(3):. 2022
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Characterization and reduction of non-endocrine cells accompanying islet-like endocrine cells differentiated from human iPSC
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Scientific Reports, 2022;12(1):4740. 2022
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3D Printed Graphene-PLA Scaffolds Promote Cell Alignment and Differentiation
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International Journal of Molecular Sciences, 2022;23(3):. 2022
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MiR-218 Promotes Adriamycin-Induced H9C2 Apoptosis by Inhibiting Stress-Associated Endoplasmic Reticulum Protein 1
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Disease Markers, 2022;2022(0):6881103. 2022
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Dynamic changes in beta-cell [Ca2+] regulates NFAT activation, gene transcription and islet gap junction communication
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Oncogene, 2021-12-31;0(0):101430. 2021-12-31
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Modulation by 17,20S(OH)2pD of Fibrosis-Related Mediators in Dermal Fibroblast Lines from Healthy Donors and from Patients with Systemic Sclerosis
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International Journal of Molecular Sciences, 2021-12-29;23(1):. 2021-12-29
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SARS-CoV-2 infects the human kidney and drives fibrosis in kidney organoids
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Cell Stem Cell, 2021-12-25;29(2):217-231.e8. 2021-12-25
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Bi-phasic effect of gelatin in myogenesis and skeletal muscle regeneration
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Disease Models & Mechanisms, 2021-12-24;14(12):. 2021-12-24
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TNFalpha Mediates Inflammation-Induced Effects on PPARG Splicing in Adipose Tissue and Mesenchymal Precursor Cells
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Cells, 2021-12-24;11(1):. 2021-12-24
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Pluripotent Stem Cell-Derived Hepatocytes Inhibit T Cell Proliferation In Vitro through Tryptophan Starvation
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Cells, 2021-12-22;11(1):. 2021-12-22
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The Non-Erythropoietic EPO Analogue Cibinetide Inhibits Osteoclastogenesis In Vitro and Increases Bone Mineral Density in Mice
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International Journal of Molecular Sciences, 2021-12-21;23(1):. 2021-12-21
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Lucanthone, Autophagy Inhibitor, Enhances the Apoptotic Effects of TRAIL through miR-216a-5p-Mediated DR5 Upregulation and DUB3-Mediated Mcl-1 Downregulation
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International Journal of Molecular Sciences, 2021-12-21;23(1):. 2021-12-21
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Immunogenicity profile in African green monkeys of a vaccine candidate based on a mutated form of human Interleukin-15
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BMC immunology, 2021-12-18;22(1):79. 2021-12-18
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Reduced Interleukin-17-Expressing Cells in Cutaneous Melanoma
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Biomedicines, 2021-12-16;9(12):. 2021-12-16
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Generation of an iPSC line (ZZUNEUi021-A) from a hypertrophic cardiomyopathy patient with TNNT2 mutation
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Stem Cell Research, 2021-12-11;58(0):102622. 2021-12-11
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Targeting AURKA in treatment of peritoneal tumor dissemination in gastrointestinal cancer
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Translational Oncology, 2021-12-10;16(0):101307. 2021-12-10
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CRIg on liver macrophages clears pathobionts and protects against alcoholic liver disease
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Nature Communications, 2021-12-09;12(1):7172. 2021-12-09
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Mesenchymal-Stromal Cell-like Melanoma-Associated Fibroblasts Increase IL-10 Production by Macrophages in a Cyclooxygenase/Indoleamine 2,3-Dioxygenase-Dependent Manner
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Silencing of p53 and CDKN1A establishes sustainable immortalized megakaryocyte progenitor cells from human iPSCs
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High-dose drug heat map analysis for drug safety and efficacy in multi-spheroid brain normal cells and GBM patient-derived cells
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PLoS ONE, 2021-12-02;16(12):e0251998. 2021-12-02
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Nucleic Acids Research, 2021-12-02;49(21):12211-12233. 2021-12-02
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Journal of Translational Medicine, 2021-11-27;19(1):482. 2021-11-27
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Nature Communications, 2021-11-25;12(1):6839. 2021-11-25
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Role of RIPK1 in SMAC mimetics-induced apoptosis in primary human HIV-infected macrophages
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Scientific Reports, 2021-11-25;11(1):22901. 2021-11-25
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G-protein-coupled receptor P2Y10 facilitates chemokine-induced CD4 T cell migration through autocrine/paracrine mediators
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Nature Communications, 2021-11-23;12(1):6798. 2021-11-23
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Tetrandrine Modulates Rheb-mTOR Signaling-Mediated Selective Autophagy and Protects Pulmonary Fibrosis
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Frontiers in Pharmacology, 2021-11-22;12(0):739220. 2021-11-22
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Loss of mutual protection between human osteoclasts and chondrocytes in damaged joints initiates osteoclast-mediated cartilage degradation by MMPs
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Scientific Reports, 2021-11-22;11(1):22708. 2021-11-22
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Isolation, Culture and Comprehensive Characterization of Biological Properties of Human Urine-Derived Stem Cells
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International Journal of Molecular Sciences, 2021-11-19;22(22):. 2021-11-19
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MTAP-related increased erythroblast proliferation as a mechanism of polycythaemia vera
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Scientific Reports, 2021-11-18;11(1):22483. 2021-11-18
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The Role of Cytokines Produced via the NLRP3 Inflammasome in Mouse Macrophages Stimulated with Dental Calculus in Osteoclastogenesis
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International Journal of Molecular Sciences, 2021-11-18;22(22):. 2021-11-18
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Low-Dose Pesticides Alter Primary Human Bone Marrow Mesenchymal Stem/Stromal Cells through ALDH2 Inhibition
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Cancers, 2021-11-14;13(22):. 2021-11-14
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Discovery of a novel Igbeta and FcgammaRIIB cross-linking antibody, ASP2713, and its potential application in the treatment of systemic lupus erythematosus
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International immunopharmacology, 2021-11-12;101(0):108343. 2021-11-12
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An integrative proteomics method identifies a regulator of translation during stem cell maintenance and differentiation
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Nature Communications, 2021-11-12;12(1):6558. 2021-11-12
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Jintiange Capsules Ameliorate Osteoarthritis by Modulating Subchondral Bone Remodeling and Protecting Cartilage Against Degradation
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Frontiers in Pharmacology, 2021-11-11;12(0):762543. 2021-11-11
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Patient-Specific iPSC-Derived Neural Differentiated and Hepatocyte-like Cells, Carrying the Compound Heterozygous Mutation p.V1023Sfs*15/p.G992R, Present the "Variant" Biochemical Phenotype of Niemann-Pick Type C1 Disease
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International Journal of Molecular Sciences, 2021-11-10;22(22):. 2021-11-10
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N-glycosylation status of Trop2 impacts its surface density, interaction with claudin-7 and exosomal release
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Archives of biochemistry and biophysics, 2021-11-10;714(0):109084. 2021-11-10
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USP39 promotes non-homologous end-joining repair by poly(ADP-ribose)-induced liquid demixing
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Nucleic Acids Research, 2021-11-08;49(19):11083-11102. 2021-11-08
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The small intestine epithelium exempts Foxp3+ Tregs from their IL-2 requirement for homeostasis and effector function
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JCI Insight, 2021-11-08;6(21):. 2021-11-08
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Chemically Defined Conditions Mediate an Efficient Induction of Dental Pulp Pluripotent-Like Stem Cells into Hepatocyte-Like Cells
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Stem Cells International, 2021-11-08;2021(0):5212852. 2021-11-08
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Improvement of an Effective Protocol for Directed Differentiation of Human Adipose Tissue-Derived Adult Mesenchymal Stem Cells to Corneal Endothelial Cells
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International Journal of Molecular Sciences, 2021-11-05;22(21):. 2021-11-05
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BRAF and MEK Inhibitors Affect Dendritic-Cell Maturation and T-Cell Stimulation
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Oncogene, 2021-11-04;22(21):. 2021-11-04
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A library of induced pluripotent stem cells from clinically well-characterized, diverse healthy human individuals
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Temporal dynamics of base excision/single-strand break repair protein complex assembly/disassembly are modulated by the PARP/NAD+/SIRT6 axis
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Cell Reports, 2021-11-02;37(5):109917. 2021-11-02
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Targeting Endoglin Expressing Cells in the Tumor Microenvironment Does Not Inhibit Tumor Growth in a Pancreatic Cancer Mouse Model
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OncoTargets and Therapy, 2021-10-29;14(0):5205-5220. 2021-10-29
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Comparative analysis of the effects of opioids in angiogenesis
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BMC anesthesiology, 2021-10-26;21(1):257. 2021-10-26
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IL-33 induces orofacial neuropathic pain through Fyn-dependent phosphorylation of GluN2B in the trigeminal spinal nucleus caudalis
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Brain, Behavior, and Immunity, 2021-10-26;0(0):. 2021-10-26
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REDD1 is a determinant of low-dose metronomic doxorubicin-elicited endothelial cell dysfunction through downregulation of VEGFR-2/3 expression
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Experimental & Molecular Medicine, 2021-10-25;0(0):. 2021-10-25
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Diverse inflammatory threats modulate astrocytes Ca2+ signaling via connexin43 hemichannels in organotypic spinal slices
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Molecular Brain, 2021-10-25;14(1):159. 2021-10-25
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Recapitulating cholangiopathy-associated necroptotic cell death in vitro using human cholangiocyte organoids
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Cellular and Molecular Gastroenterology and Hepatology, 2021-10-23;0(0):. 2021-10-23
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Species-Specific Inhibition of Necroptosis by HCMV UL36
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Viruses, 2021-10-22;13(11):. 2021-10-22
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Macrophage Polarization Related to Crystal Phases of Calcium Phosphate Biomaterials
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International Journal of Molecular Sciences, 2021-10-19;22(20):. 2021-10-19
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ELTD1 Activation Induces an Endothelial-EMT Transition to a Myofibroblast Phenotype
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International Journal of Molecular Sciences, 2021-10-19;22(20):. 2021-10-19
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A highly efficient method for the production and purification of recombinant human CXCL8
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PLoS ONE, 2021-10-15;16(10):e0258270. 2021-10-15
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Fluorescent glycan fingerprinting of SARS2 spike proteins
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Scientific Reports, 2021-10-14;11(1):20428. 2021-10-14
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OSMI-1 Enhances TRAIL-Induced Apoptosis through ER Stress and NF-kappaB Signaling in Colon Cancer Cells
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International Journal of Molecular Sciences, 2021-10-14;22(20):. 2021-10-14
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PI3Kdelta Sustains Keratinocyte Hyperproliferation and Epithelial Inflammation: Implications for a Topically Druggable Target in Psoriasis
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Protocol for the Stimulating beta3-Adrenergic Receptors for Peripheral Artery Disease (STAR-PAD) trial: a double-blinded, randomised, placebo-controlled study evaluating the effects of mirabegron on functional performance in patients with peripheral arterial disease
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Tumor Necrosis Factor-alpha utilizes MAPK/NFkappaB pathways to induce cholesterol-25 hydroxylase for amplifying pro-inflammatory response via 25-hydroxycholesterol-integrin-FAK pathway
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Profiling of Human Neural Crest Chemoattractant Activity as a Replacement of Fetal Bovine Serum for In Vitro Chemotaxis Assays
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Radiotherapy Combined with PD-1 Inhibition Increases NK Cell Cytotoxicity towards Nasopharyngeal Carcinoma Cells
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IL-18 binding protein suppresses IL-17-induced osteoclastogenesis and rectifies type 17 helper T cell / regulatory T cell imbalance in rheumatoid arthritis
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RAS specific protease induces irreversible growth arrest via p27 in several KRAS mutant colorectal cancer cell lines
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Scientific Reports, 2021-09-09;11(1):17925. 2021-09-09
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PLoS ONE, 2021-08-26;16(8):e0256237. 2021-08-26
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International journal of biological sciences, 2021-08-19;17(13):3583-3594. 2021-08-19
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The Journal of nutritional biochemistry, 2021-08-15;0(0):108842. 2021-08-15
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Deciphering the biology of KIR2DL3+ T lymphocytes that are associated to relapse in haploidentical HSCT
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Histone deacetylase inhibitor panobinostat induces antitumor activity in epithelioid sarcoma and rhabdoid tumor by growth factor receptor modulation
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JCI Insight, 2021-06-22;0(0):. 2021-06-22
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Repositioning Trimebutine Maleate as a Cancer Treatment Targeting Ovarian Cancer Stem Cells
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Cells, 2021-01-30;10(2):. 2021-01-30
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High Level Stable Expression of Recombinant HIV gp120 in Glutamine Synthetase Gene Deficient HEK293T Cells
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Engagement of TREM2 by a novel monoclonal antibody induces activation of microglia and improves cognitive function in Alzheimer's disease models
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Astrocyte-Derived TGF&beta1 Facilitates Blood-Brain Barrier Function via Non-Canonical Hedgehog Signaling in Brain Microvascular Endothelial Cells
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The Journal of Biological Chemistry, 2021-01-08;296(0):100246. 2021-01-08
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Liver fibrosis-induced muscle atrophy is mediated by elevated levels of circulating TNF&alpha
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Molecular dynamics simulations and functional studies reveal that hBD-2 binds SARS-CoV-2 spike RBD and blocks viral entry into ACE2 expressing cells
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TARM1 contributes to development of arthritis by activating dendritic cells through recognition of collagens
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Benefit of Belatacept in Cord Blood-Derived Regulatory T Cell-Mediated Suppression of Alloimmune Response
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Identification of novel CD44v6-binding peptides that block CD44v6 and deliver a pro-apoptotic peptide to tumors to inhibit tumor growth and metastasis in mice
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Species-Specific Inhibition of Necroptosis by HCMV UL36
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CRIg on liver macrophages clears pathobionts and protects against alcoholic liver disease
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Benefit of Belatacept in Cord Blood-Derived Regulatory T Cell-Mediated Suppression of Alloimmune Response
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CAR-T cell-mediated depletion of immunosuppressive tumor-associated macrophages promotes endogenous antitumor immunity and augments adoptive immunotherapy
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Improvement of an Effective Protocol for Directed Differentiation of Human Adipose Tissue-Derived Adult Mesenchymal Stem Cells to Corneal Endothelial Cells
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BRAF and MEK Inhibitors Affect Dendritic-Cell Maturation and T-Cell Stimulation
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Isolation, Culture and Comprehensive Characterization of Biological Properties of Human Urine-Derived Stem Cells
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Macrophage Polarization Related to Crystal Phases of Calcium Phosphate Biomaterials
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IDH1 mutations induce organelle defects via dysregulated phospholipids
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Astrocyte-Derived TGF&beta1 Facilitates Blood-Brain Barrier Function via Non-Canonical Hedgehog Signaling in Brain Microvascular Endothelial Cells
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Patient-Specific iPSC-Derived Neural Differentiated and Hepatocyte-like Cells, Carrying the Compound Heterozygous Mutation p.V1023Sfs*15/p.G992R, Present the "Variant" Biochemical Phenotype of Niemann-Pick Type C1 Disease
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S1P Increases VEGF Production in Osteoblasts and Facilitates Endothelial Progenitor Cell Angiogenesis by Inhibiting miR-16-5p Expression via the c-Src/FAK Signaling Pathway in Rheumatoid Arthritis
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DutaFabs are engineered therapeutic Fab fragments that can bind two targets simultaneously
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Chemically Defined Conditions Mediate an Efficient Induction of Dental Pulp Pluripotent-Like Stem Cells into Hepatocyte-Like Cells
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CRIPTO antagonist ALK4L75A-Fc inhibits breast cancer cell plasticity and adaptation to stress
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Chemerin-156 is the Active Isoform in Human Hepatic Stellate Cells
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PLoS ONE, 2020-10-13;15(10):e0240469. 2020-10-13
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Discovery of novel artemisinin-sulfonamidehybrids as potential carbonicanhydraseIX inhibitors with improved antiproliferative activities
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Bioorg Chem, 2020-10-08;104(0):104347. 2020-10-08
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Generation of an immortalised erythroid cell line from haematopoietic stem cells of a haemoglobin E/&beta-thalassemia patient
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Aptamer targeted therapy potentiates immune checkpoint blockade in triple-negative breast cancer
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SMOC2, an intestinal stem cell marker, is an independent prognostic marker associated with better survival in colorectal cancers
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Clostridial C3 Toxins Enter and Intoxicate Human Dendritic Cells
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Biology (Basel), 2020-08-17;9(8):. 2020-08-17
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A novel rabbit derived anti-HER2 antibody with pronounced therapeutic effectiveness on HER2-positive breast cancer cells in vitro and in humanized tumor mice (HTM)
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Lactobacillus sakei suppresses collagen-induced arthritis and modulates the differentiation of T helper 17 cells and regulatory B cells
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Thrombomodulin facilitates peripheral nerve regeneration through regulating M1/M2 switching
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PLoS ONE, 2020-08-14;15(8):e0236212. 2020-08-14
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Cytisine attenuates bone loss of ovariectomy mouse by preventing RANKL-induced osteoclastogenesis
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Collagen VIalpha2 chain deficiency causes trabecular bone loss by potentially promoting osteoclast differentiation through enhanced TNFalpha signaling
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Exp. Gerontol., 2020-08-13;140(0):111057. 2020-08-13
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Cross-Species Transmission and Evolution of SIV Chimpanzee Progenitor Viruses Toward HIV-1 in Humanized Mice
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Front Microbiol, 2020-08-11;11(0):1889. 2020-08-11
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Activator protein-1 transactivation of the major immediate early locus is a determinant of cytomegalovirus reactivation from latency
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Proc. Natl. Acad. Sci. U.S.A., 2020-08-11;117(34):20860-20867. 2020-08-11
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Dopamine transporter neuroimaging accurately assesses the maturation of dopamine neurons in a preclinical model of Parkinson's disease
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Reversal of pre-existing NGFR-driven tumor and immune therapy resistance
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Nat Commun, 2020-08-07;11(1):3946. 2020-08-07
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NF-kappaB-dependent miR-31/155 biogenesis is essential for TNF-alpha-induced impairment of endothelial progenitor cell function
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Exp. Mol. Med., 2020-08-07;0(0):. 2020-08-07
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Isolation of Two Novel Human Anti-CTLA-4 mAbs with Intriguing Biological Properties on Tumor and NK Cells
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Cancers (Basel), 2020-08-06;12(8):. 2020-08-06
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Supporting data on enhanced reprogramming of human CD34+ hematopoietic stem cells to induced pluripotent stem cells using human placenta-derived cell conditioned medium
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Data Brief, 2020-08-06;32(0):106140. 2020-08-06
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'Psoriasis 1' reduces T‑lymphocyte‑mediated inflammation in patients with psoriasis by inhibiting vitamin D receptor‑mediated STAT4 inactivation.
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Int J Mol Med, 2020-08-06;46(4):1538-1550. 2020-08-06
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Erythromycin inhibits neutrophilic inflammation and mucosal disease by upregulating DEL-1
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JCI Insight, 2020-08-06;0(0):. 2020-08-06
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Protein tyrosine phosphatase 1B as a therapeutic target for Graves' orbitopathy in an in vitro model
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PLoS ONE, 2020-08-06;15(8):e0237015. 2020-08-06
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Phthalate inhibits Leydig cell differentiation and promotes adipocyte differentiation
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Chemosphere, 2020-08-06;262(0):127855. 2020-08-06
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Frequency Shift of a SH-SAW Biosensor with Glutaraldehyde and 3-Aminopropyltriethoxysilane Functionalized Films for Detection of Epidermal Growth Factor
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Novel ex vivo disease model for extramammary Paget�s disease using the cancer tissue-originated spheroid method
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IL-17F induces inflammation, dysfunction and cell death in mouse islets
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A Switch in p53 Dynamics Marks Cells That Escape from DSB-Induced Cell Cycle Arrest
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Metabolic competition between host and pathogen dictates inflammasome responses to fungal infection
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PLoS Pathog., 2020-08-04;16(8):e1008695. 2020-08-04
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CD154 inhibits death of T cells via a Cis interaction with the alpha5beta1 integrin
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Protective Immune Responses Elicited by Deglycosylated Live-Attenuated Simian Immunodeficiency Virus Vaccine Are Associated with IL-15 Effector Functions
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Robotic High-Throughput Biomanufacturing and Functional Differentiation of Human Pluripotent Stem Cells
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bioRxiv, 2020-08-03;0(0):. 2020-08-03
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Oxidized Low-Density Lipoprotein Induces Macrophage Production of Prothrombotic Microparticles
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Relation of Neutrophil Gelatinase-Associated Lipocalin Overexpression to the Resistance to Apoptosis of Tumor B Cells in Chronic Lymphocytic Leukemia
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Cancers (Basel), 2020-07-31;12(8):. 2020-07-31
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Cleavage of proteoglycans, plasma proteins and the platelet-derived growth factor receptor in the hemorrhagic process induced by snake venom metalloproteinases
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Sci Rep, 2020-07-31;10(1):12912. 2020-07-31
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IFN-gamma promoted exosomes from mesenchymal stem cells to attenuate colitis via miR-125a and miR-125b
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Cell Death Dis, 2020-07-30;11(7):603. 2020-07-30
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New chimeric TLR7/NOD2 agonist is a potent adjuvant to induce mucosal immune responses
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EBioMedicine, 2020-07-30;58(0):102922. 2020-07-30
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Thrombin alters the synthesis and processing of CYR61/CCN1 in human corneal stromal fibroblasts and myofibroblasts through multiple distinct mechanisms
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Mol. Vis., 2020-07-29;26(0):540-562. 2020-07-29
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Developmental GABA polarity switch and neuronal plasticity in Bioengineered Neuronal Organoids
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Nat Commun, 2020-07-29;11(1):3791. 2020-07-29
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Epigenetic regulator function through mouse gastrulation
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Nature, 2020-07-29;584(7819):102-108. 2020-07-29
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NLRP3 Inflammasome Activation in Lung Vascular Endothelial Cells Contributes to Intestinal Ischemia/Reperfusion-Induced Acute Lung Injury
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Inhibition of HAS2 and hyaluronic acid production by 1,25-Dihydroxyvitamin D3 in breast cancer
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Oncotarget, 2020-07-28;11(30):2889-2905. 2020-07-28
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Lysosome-targeted beta-galactosidase negatively regulates neuraminidase 1 (NEU1) and promotes NEU1 deficiency in GM1 gangliosidosis
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TNF-&alpha controls Lipocalin-2 expression in PC-3 prostate cancer cells
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Cytokine, 2020-07-24;135(0):155214. 2020-07-24
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Epigenetic transcriptional reprogramming by WT1 mediates a repair response during podocyte injury
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Sci Adv, 2020-07-24;6(30):eabb5460. 2020-07-24
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Brd4-p300 inhibition down-regulates Nox4 and accelerates lung fibrosis resolution in aged mice
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JCI Insight, 2020-07-23;0(0):. 2020-07-23
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Placental Mesenchymal Stromal Cells (PMSCs) and PMSC-Derived Extracellular Vesicles (PMSC-EVs) Attenuated Renal Fibrosis in Rats with Unilateral Ureteral Obstruction (UUO) by Regulating CD4+ T Cell Polarization
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Stem Cells Int, 2020-07-22;2020(0):2685820. 2020-07-22
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Gintonin influences the morphology and motility of adult brain neurons via LPA receptors
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Journal of Ginseng Research, 2020-07-21;45(3):401-407. 2020-07-21
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Cell Death Differ., 2020-07-21;0(0):. 2020-07-21
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Maturational Changes in Mouse Cutaneous Touch and Piezo2-Mediated Mechanotransduction
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Cell Rep, 2020-07-21;32(3):107912. 2020-07-21
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STEEP mediates STING ER exit and activation of signaling
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Nat. Immunol., 2020-07-20;21(8):868-879. 2020-07-20
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Ozone-derived oxysterols impair lung macrophage phagocytosis via adduction of some phagocytosis receptors
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Isolation and characterization of neural crest-like progenitor cells in human umbilical cord blood
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Regenerative Therapy, 2020-07-18;15(0):53-63. 2020-07-18
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Human multipotent adult progenitor cell-conditioned medium improves wound healing through modulating inflammation and angiogenesis in mice
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Stem Cell Res Ther, 2020-07-17;11(1):299. 2020-07-17
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Isoliquiritigenin ameliorates caerulein-induced chronic pancreatitis by inhibiting the activation of PSCs and pancreatic infiltration of macrophages
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Effect of IFN-gamma on the kynurenine/tryptophan ratio in monolayer-cultured keratinocytes and a 3D reconstructed human epidermis model
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J. Dermatol. Sci., 2020-07-17;0(0):. 2020-07-17
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Disruption of the tumour-associated EMP3 enhances erythroid proliferation and causes the MAM-negative phenotype
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Nat Commun, 2020-07-16;11(1):3569. 2020-07-16
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Anti-Cancer Activity of Acriflavine as Metabolic Inhibitor of OXPHOS in Pancreas Cancer Xenografts
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Onco Targets Ther, 2020-07-15;13(0):6907-6916. 2020-07-15
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Generation of an induced pluripotent stem cell line KUMCi001-A from CD34+ bone marrow cells of a patient with acute lymphoblastic leukemia using human placenta-derived cell conditioned medium
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Stem Cell Res, 2020-07-13;47(0):101913. 2020-07-13
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HMGB1 amplifies ILC2-induced type-2 inflammation and airway smooth muscle�remodelling
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PLoS Pathog., 2020-07-13;16(7):e1008651. 2020-07-13
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Chemical synthesis of a sulfated d-glucosamine library and evaluation of cell proliferation capabilities
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Carbohydr. Res., 2020-07-12;495(0):108085. 2020-07-12
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Regulation of Intestinal Epithelial Barrier and Immune Function by activated T cells
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Cell Mol Gastroenterol Hepatol, 2020-07-11;0(0):. 2020-07-11
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METTL14 aggravates endothelial inflammation and atherosclerosis by increasing FOXO1 N6-methyladeosine modifications
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Theranostics, 2020-07-11;10(20):8939-8956. 2020-07-11
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Dynamic CCN3 expression in the murine CNS does not confer essential roles in myelination or remyelination
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Proc. Natl. Acad. Sci. U.S.A., 2020-07-10;0(0):. 2020-07-10
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Annexin A5 regulates hepatic macrophage polarization via directly targeting PKM2 and ameliorates NASH
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Redox Biol, 2020-07-08;36(0):101634. 2020-07-08
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IL-6 Trans-Signaling in the Brain Influences the Metabolic Phenotype of the 3xTg-AD Mouse Model of Alzheimer's Disease
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Cells, 2020-07-02;9(7):. 2020-07-02
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BMC Cancer, 2020-07-02;20(1):619. 2020-07-02
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Stiffness-matched biomaterial implants for cell delivery: clinical, intraoperative ultrasound elastography provides a 'target' stiffness for hydrogel synthesis in spinal cord injury
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LncRNA SNHG6 regulating Hedgehog signaling pathway and affecting the biological function of gallbladder carcinoma cells through targeting miR-26b-5p
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Eur Rev Med Pharmacol Sci, 2020-07-01;24(14):7598-7611. 2020-07-01
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Cell Death Dis, 2020-07-01;11(7):497. 2020-07-01
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iPSC-derived endothelial cell response to hypoxia via SDF1a/CXCR4 axis facilitates incorporation to revascularize ischemic retina
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Molecular Engineering Strategies Tailoring the Apoptotic Response to a MET Therapeutic Antibody
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The effects of BAFF on T lymphocytes in chronic obstructive pulmonary disease
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Enhanced STAT3 phosphorylation and PD-L1 expression in myeloid dendritic cells indicate impaired IL-27Ralpha signaling in type 1 diabetes
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Modulation of lymphocyte-mediated tissue repair by rational design of heterocyclic aryl hydrocarbon receptor agonists
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Cells, 2020-01-10;9(1):. 2020-01-10
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Modulating Tumor-Associated Macrophage Polarization by Synthetic and Natural PPAR&gamma Ligands as a Potential Target in Breast Cancer
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The Influence of Cell Culture Density on the Cytotoxicity of Adipose-Derived Stem Cells Induced by L-Ascorbic Acid-2-Phosphate
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Modulation of Cytokine-Induced Astrocytic Endothelin-1 Production as a Possible New Approach to the Treatment of Multiple Sclerosis
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Front Pharmacol, 2020-01-08;10(0):1491. 2020-01-08
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Quantitative Efficacy and Fate of Mesenchymal Stromal Cells Targeted to Cardiac Sites by Radiofrequency Catheter Ablation
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Cell Rep, 2020;30(8):2758-2775.e6. 2020
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Suppressed humoral immunity is associated with dengue nonstructural protein NS1-elicited anti-death receptor antibody fractions in mice
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Differential regulation of breast cancer bone metastasis by PARP1 and PARP2
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Periostin Activation of Integrin Receptors on Sensory Neurons Induces Allergic Itch
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Rosuvastatin Prevents the Exacerbation of Atherosclerosis in Ligature-Induced Periodontal Disease Mouse Model
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Viruses, 2019-09-23;11(10):. 2019-09-23
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Inhibition of Tyrosine-Phosphorylated STAT3 in Human Breast and Lung Cancer Cells by Manuka Honey is Mediated by Selective Antagonism of the IL-6 Receptor
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Solid state fermentation process with Aspergillus kawachii enhances the cancer-suppressive potential of silkworm larva in hepatocellular carcinoma cells
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Cytokine, 2019-09-03;125(0):154834. 2019-09-03
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The MicroRNA-92a/Sp1/MyoD Axis Regulates Hypoxic Stimulation of Myogenic Lineage Differentiation in Mouse Embryonic Stem Cells
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Cancers (Basel), 2019-08-15;11(8):. 2019-08-15
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Phase I study of cellular therapy using ex vivo expanded natural killer cells from autologous peripheral blood mononuclear cells combined with rituximab-containing chemotherapy for relapsed CD20-positive malignant lymphoma patients
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Cytokine, 2019-07-29;123(0):154782. 2019-07-29
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BMC Musculoskelet Disord, 2019-05-29;20(1):257. 2019-05-29
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Arthritis Res. Ther., 2019-04-25;21(1):105. 2019-04-25
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PLoS Pathog., 2019-04-22;15(4):e1007625. 2019-04-22
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FEBS Open Bio, 2019-04-11;9(5):859-869. 2019-04-11
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Sulforaphane-Enriched Broccoli Sprouts Pretreated by Pulsed Electric Fields Reduces Neuroinflammation and Ameliorates Scopolamine-Induced Amnesia in Mouse Brain through Its Antioxidant Ability via Nrf2-HO-1 Activation
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Oxid Med Cell Longev, 2019-03-27;2019(0):3549274. 2019-03-27
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Biochem Biophys Rep, 2019-03-20;18(0):100624. 2019-03-20
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Sci Rep, 2019-03-07;9(1):3825. 2019-03-07
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EBioMedicine, 2019-03-05;41(0):670-682. 2019-03-05
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Sci Rep, 2019-03-01;9(1):3230. 2019-03-01
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Cytokine, 2019-03-01;117(0):84-90. 2019-03-01
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Aging (Albany NY), 2019-02-14;11(3):1030-1044. 2019-02-14
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Microporous polysaccharide multilayer coated BCP composite scaffolds with immobilised calcitriol promote osteoporotic bone regeneration both in vitro and in vivo
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Theranostics, 2019-01-30;9(4):1125-1143. 2019-01-30
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Disrupting the IL-36 and IL-23/IL-17 loop underlies the efficacy of calcipotriol and corticosteroid therapy for psoriasis
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JCI Insight, 2019-01-24;4(2):. 2019-01-24
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Interferon lambda protects the female reproductive tract against Zika virus infection
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Mucosal Immunol, 2019-01-07;12(2):445-456. 2019-01-07
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Comparison between Polybutylcyanoacrylate Nanoparticles with Either Surface-Adsorbed or Encapsulated Brain-Derived Neurotrophic Factor on the Neural Differentiation of iPSCs
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Inflammatory Serine Proteases Play a Critical Role in the Early Pathogenesis of Diabetic Cardiomyopathy
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Nat. Immunol., 2018-11-19;0(0):. 2018-11-19
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Human neural stem cell-derived neuron/astrocyte co-cultures respond to La Crosse virus infection with proinflammatory cytokines and chemokines
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J Neuroinflammation, 2018-11-15;15(1):315. 2018-11-15
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High-throughput three-dimensional chemotactic assays reveal steepness-dependent complexity in neuronal sensation to molecular gradients
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Nat Commun, 2018-11-12;9(1):4745. 2018-11-12
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The deubiquitinase CYLD is a specific checkpoint of the STING antiviral signaling pathway
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PLoS Pathog., 2018-11-02;14(11):e1007435. 2018-11-02
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IL-1 and TGF-? Modulation of Epithelial Basement Membrane Components Perlecan and Nidogen Production by Corneal Stromal Cells
Authors: P Saikia, S Thangavadi, CS Medeiros, L Lassance, RC de Oliveir, SE Wilson
Invest. Ophthalmol. Vis. Sci., 2018-11-01;59(13):5589-5598. 2018-11-01
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ASXL1 and SETBP1 mutations promote leukaemogenesis by repressing TGF? pathway genes through histone deacetylation
Authors: M Saika, D Inoue, R Nagase, N Sato, A Tsuchiya, T Yabushita, T Kitamura, S Goyama
Sci Rep, 2018-10-26;8(1):15873. 2018-10-26
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CXCR4 Accelerates Osteoclastogenesis Induced by Non-Small Cell Lung Carcinoma Cells Through Self-Potentiation and VCAM1 Secretion
Authors: T Liao, W Chen, J Sun, Y Zhang, X Hu, S Yang, H Qiu, S Li, T Chu
Cell. Physiol. Biochem., 2018-10-24;50(3):1084-1099. 2018-10-24
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The E3 ubiquitin ligase TRIM25 regulates adipocyte differentiation via proteasome-mediated degradation of PPAR?
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Exp. Mol. Med., 2018-10-15;50(10):135. 2018-10-15
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Schwann cell-like differentiated adipose stem cells promote neurite outgrowth via secreted exosomes and RNA transfer
Authors: RC Ching, M Wiberg, PJ Kingham
Stem Cell Res Ther, 2018-10-11;9(1):266. 2018-10-11
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Generation and characterization of two human induced pluripotent stem cell (hiPSC) lines homozygous for the Apolipoprotein e4 (APOE4) risk variant-Alzheimer's disease (ASUi005-A) and healthy non-demented control (ASUi006-A)
Authors: N Brookhouse, P Zhang, R Caselli, JJ Kim, DA Brafman
Stem Cell Res, 2018-09-21;32(0):145-149. 2018-09-21
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Mouse Mast Cell Protease 4 Deletion Protects Heart Function and Survival After Permanent Myocardial Infarction
Authors: M Houde, A Schwertani, H Touil, L Desbiens, O Sarrhini, R Lecomte, M Lepage, H Gagnon, S Takai, G Pejler, D Jacques, F Gobeil, R Day, P D'Orléans-
Front Pharmacol, 2018-08-31;9(0):868. 2018-08-31
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The BTK Inhibitor ARQ 531 Targets Ibrutinib Resistant CLL and Richter's Transformation
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Cancer Discov, 2018-08-09;0(0):. 2018-08-09
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Affinity maturation of an TpoR targeting antibody in full-length IgG form for enhanced agonist activity
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Protein Eng. Des. Sel., 2018-07-01;0(0):. 2018-07-01
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Neuronal subtype determines HSV-1 Latency-Associated-Transcript (LAT) promoter activity during latency
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J. Virol., 2018-06-13;0(0):. 2018-06-13
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Development of Versatile Human In Vitro Vascularized Adipose Tissue Model with Serum-Free Angiogenesis and Natural Adipogenesis Induction
Authors: O Huttala, M Palmroth, P Hemminki, T Toimela, T Heinonen, T Ylikomi, JR Sarkanen
Basic Clin. Pharmacol. Toxicol., 2018-04-27;0(0):. 2018-04-27
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Contribution of three-dimensional architecture and tumor-associated fibroblasts to hepcidin regulation in breast cancer
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Oncogene, 2018-04-26;37(29):4013-4032. 2018-04-26
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The group VIA calcium-independent phospholipase A2 and NFATc4 pathway mediates IL-1β-induced expression of chemokines CCL2 and CXCL10 in rat fibroblasts
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FEBS J., 2018-04-18;0(0):. 2018-04-18
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A Nonpyroptotic IFN-?-Triggered Cell Death Mechanism in Nonphagocytic Cells Promotes Salmonella Clearance In Vivo
Authors: JP Ingram, S Tursi, T Zhang, W Guo, C Yin, M A Wynosky-, J van der He, KQ Cai, M Yamamoto, BB Finlay, IE Brodsky, SI Grivenniko, Ç Tükel, S Balachandr
J. Immunol., 2018-04-13;0(0):. 2018-04-13
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Expression of mutant Asxl1 perturbs hematopoiesis and promotes susceptibility to leukemic transformation
Authors: R Nagase, D Inoue, A Pastore, T Fujino, HA Hou, N Yamasaki, S Goyama, M Saika, A Kanai, Y Sera, S Horikawa, Y Ota, S Asada, Y Hayashi, KC Kawabata, R Takeda, HF Tien, H Honda, O Abdel-Waha, T Kitamura
J. Exp. Med., 2018-04-11;0(0):. 2018-04-11
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EphrinB2/EphB4 signaling regulates non-sprouting angiogenesis by VEGF
Authors: E Groppa, S Brkic, A Uccelli, G Wirth, P Korpisalo-, M Filippova, B Dasen, V Sacchi, MG Muraro, M Trani, S Reginato, R Gianni-Bar, S Ylä-Herttu, A Banfi
EMBO Rep., 2018-04-11;0(0):. 2018-04-11
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Injectable hydrogels of optimized acellular nerve for injection in the injured spinal cord
Authors: RC Cornelison, E Gonzalez-R, SL Porvasnik, SM Wellman, JH Park, DD Fuller, CE Schmidt
Biomed Mater, 2018-03-21;0(0):. 2018-03-21
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TNFSF14 (LIGHT) Exhibits Inflammatory Activities in Lung Fibroblasts Complementary to IL-13 and TGF-β
Authors: R da Silva A, AK Mehta, L Madge, J Tocker, M Croft
Front Immunol, 2018-03-19;9(0):576. 2018-03-19
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Telatinib is an effective targeted therapy for pseudomyogenic hemangioendothelioma
Authors: DGP van IJzend, S Sleijfer, H Gelderblom, FALM Eskens, GJ van Leende, K Szuhai, JVMG Bovee
Clin. Cancer Res., 2018-03-06;0(0):. 2018-03-06
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IL-23-induced macrophage polarization and its pathological roles in mice with imiquimod-induced psoriasis
Authors: Y Hou, L Zhu, H Tian, HX Sun, R Wang, L Zhang, Y Zhao
Protein Cell, 2018-03-05;0(0):. 2018-03-05
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PINK1 autophosphorylation is required for ubiquitin recognition
Authors: S Rasool, N Soya, L Truong, N Croteau, GL Lukacs, JF Trempe
EMBO Rep., 2018-02-23;0(0):. 2018-02-23
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Downregulation of microRNA-448 inhibits IL-1?-induced cartilage degradation in human chondrocytes via upregulation of matrilin-3
Authors: H Yang, D Wu, H Li, N Chen, Y Shang
Cell. Mol. Biol. Lett., 2018-02-22;23(0):7. 2018-02-22
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Inhibition of IL-10 and TGF-? receptors on dendritic cells enhances activation of effector T-cells to kill cholangiocarcinoma cells
Authors: C Thepmalee, A Panya, M Junking, T Chieochans, PT Yenchitsom
Hum Vaccin Immunother, 2018-02-21;0(0):0. 2018-02-21
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Mesenchymal Wnt/?-catenin signaling limits tooth number
Authors: E Järvinen, J Shimomura-, A Balic, M Jussila, I Thesleff
Development, 2018-02-21;0(0):. 2018-02-21
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Monocyte chemoattractant protein 1 and fractalkine play opposite roles in angiogenesisviarecruitment of different macrophage subtypes
Authors: L Chen, GQ Liu, HY Wu, J Jin, X Yin, D Li, PR Lu
Int J Ophthalmol, 2018-02-18;11(2):216-222. 2018-02-18
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Distinct CD40L receptors mediate inflammasome activation and secretion of IL-1? and MCP-1 in cultured human retinal pigment epithelial cells
Authors: ZM Bian, MG Field, SG Elner, JM Kahlenberg, VM Elner
Exp. Eye Res., 2018-02-16;170(0):29-39. 2018-02-16
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Beta cell extracellular vesicle miR-21-5p cargo is increased in response to inflammatory cytokines and serves as a biomarker of type 1 diabetes
Authors: AJ Lakhter, RE Pratt, RE Moore, KK Doucette, BF Maier, LA DiMeglio, EK Sims
Diabetologia, 2018-02-14;0(0):. 2018-02-14
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The MtDMI2-MtPUB2 negative feedback loop plays a role in nodulation homeostasis
Authors: J Liu, J Deng, F Zhu, Y Li, Z Lu, P Qin, T Wang, J Dong
Plant Physiol., 2018-02-13;0(0):. 2018-02-13
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Antitumor Efficacy of Human Monocyte-Derived Dendritic Cells: Comparing Effects of two Monocyte Isolation Methods
Authors: GS Marques, Z Silva, PA Videira
Biol Proced Online, 2018-02-02;20(0):4. 2018-02-02
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Dynamic Ligand Discrimination in the Notch Signaling Pathway
Authors: N Nandagopal, LA Santat, L LeBon, D Sprinzak, ME Bronner, MB Elowitz
Cell, 2018-02-01;172(4):869-880.e19. 2018-02-01
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Circuit Design Features of a Stable Two-Cell System
Authors: X Zhou, RA Franklin, M Adler, JB Jacox, W Bailis, JA Shyer, RA Flavell, A Mayo, U Alon, R Medzhitov
Cell, 2018-02-01;172(4):744-757.e17. 2018-02-01
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Nanoscale Dynamism of Actin Enables Secretory Function in Cytolytic Cells
Authors: AF Carisey, EM Mace, MB Saeed, DM Davis, JS Orange
Curr. Biol., 2018-02-01;0(0):. 2018-02-01
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Iron released from reactive microglia by noggin improves myelin repair in the ischemic brain
Authors: JA Shin, YA Kim, HW Kim, HS Kim, KE Lee, JL Kang, EM Park
Neuropharmacology, 2018-01-31;0(0):. 2018-01-31
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MicroRNA-31 is required for astrocyte specification
Authors: GP Meares, R Rajbhandar, M Gerigk, CL Tien, C Chang, SC Fehling, A Rowse, KC Mulhern, S Nair, GK Gray, NF Berbari, M Bredel, EN Benveniste, SE Nozell
Glia, 2018-01-30;0(0):. 2018-01-30
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TGF-?-Induced CD8CD103Regulatory T Cells Show Potent Therapeutic Effect on Chronic Graft-versus-Host Disease Lupus by Suppressing B Cells
Authors: H Zhong, Y Liu, Z Xu, P Liang, H Yang, X Zhang, J Zhao, J Chen, S Fu, Y Tang, J Lv, J Wang, N Olsen, A Xu, SG Zheng
Front Immunol, 2018-01-30;9(0):35. 2018-01-30
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Guidance of super-enhancers in regulation of IL-9 induction and airway inflammation
Authors: X Xiao, Y Fan, J Li, X Zhang, X Lou, Y Dou, X Shi, P Lan, Y Xiao, L Minze, XC Li
J. Exp. Med., 2018-01-16;0(0):. 2018-01-16
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Metabolic Induction of Trained Immunity through the Mevalonate Pathway
Authors: S Bekkering, RJW Arts, B Novakovic, I Kourtzelis, CDCC van der He, Y Li, CD Popa, R Ter Horst, J van Tuijl, RT Netea-Maie, FL van de Vee, T Chavakis, LAB Joosten, JWM van der Me, H Stunnenber, NP Riksen, MG Netea
Cell, 2018-01-11;172(1):135-146.e9. 2018-01-11
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IL-10 correlates with the expression of carboxypeptidase B2 and lymphovascular invasion in inflammatory breast cancer: The potential role of tumor infiltrated macrophages
Authors: HT Mohamed, N El-Hussein, EA El-Ghonaim, SA Ibrahim, ZA Bazzi, D Cavallo-Me, MB Boffa, M El-Shinawi, MM Mohamed
Curr Probl Cancer, 2018-01-10;0(0):. 2018-01-10
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Targeting anticoagulant protein S to improve hemostasis in hemophilia
Authors: R Prince, L Bologna, M Manetti, D Melchiorre, I Rosa, N Dewarrat, S Suardi, P Amini, JA Fernández, L Burnier, C Quarroz, MD Reina Caro, Y Matsumura, JA Kremer Hov, JH Griffin, HU Simon, L Ibba-Manne, F Saller, S Calzavarin, A Angelillo-
Blood, 2018-01-09;0(0):. 2018-01-09
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The deubiquitinase CYLD is a specific checkpoint of the STING antiviral signaling pathway
Authors: L Zhang, N Wei, Y Cui, Z Hong, X Liu, Q Wang, S Li, H Liu, H Yu, Y Cai, Q Wang, J Zhu, W Meng, Z Chen, C Wang
PLoS Pathog., 2018;14(11):e1007435. 2018
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High-throughput three-dimensional chemotactic assays reveal steepness-dependent complexity in neuronal sensation to molecular gradients
Authors: Z Xu, P Fang, B Xu, Y Lu, J Xiong, F Gao, X Wang, J Fan, P Shi
Nat Commun, 2018;9(1):4745. 2018
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Human neural stem cell-derived neuron/astrocyte co-cultures respond to La Crosse virus infection with proinflammatory cytokines and chemokines
Authors: BE Dawes, J Gao, C Atkins, JT Nelson, K Johnson, P Wu, AN Freiberg
J Neuroinflammation, 2018;15(1):315. 2018
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DEL-1 promotes macrophage efferocytosis and clearance of inflammation
Authors: I Kourtzelis, X Li, I Mitroulis, D Grosser, T Kajikawa, B Wang, M Grzybek, J von Reness, A Czogalla, M Troullinak, A Ferreira, C Doreth, K Ruppova, LS Chen, K Hosur, JH Lim, KJ Chung, S Grossklaus, AK Tausche, LAB Joosten, NM Moutsopoul, B Wielockx, A Castrillo, JM Korostoff, Ü Coskun, G Hajishenga, T Chavakis
Nat. Immunol., 2018;0(0):. 2018
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A comparative pharmacokinetic study of PARP inhibitors demonstrates favorable properties for niraparib efficacy in preclinical tumor models
Authors: K Sun, K Mikule, Z Wang, G Poon, A Vaidyanath, G Smith, ZY Zhang, J Hanke, S Ramaswamy, J Wang
Oncotarget, 2018;9(98):37080-37096. 2018
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ASXL1 and SETBP1 mutations promote leukaemogenesis by repressing TGF? pathway genes through histone deacetylation
Authors: M Saika, D Inoue, R Nagase, N Sato, A Tsuchiya, T Yabushita, T Kitamura, S Goyama
Sci Rep, 2018;8(1):15873. 2018
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Total HLA Class I Antigen Loss with the Downregulation of Antigen-Processing Machinery Components in Two Newly Established Sarcomatoid Hepatocellular Carcinoma Cell Lines
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J Immunol Res, 2018;2018(0):8363265. 2018
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Effects of the Extracts from Fruit and Stem of Camellia japonica on Induced Pluripotency and Wound Healing
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J Clin Med, 2018;7(11):. 2018
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Trisomy silencing by XIST normalizes Down syndrome cell pathogenesis demonstrated for hematopoietic defects in vitro
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Nat Commun, 2018;9(1):5180. 2018
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Botulinum toxin blocks mast cells and prevents rosacea like inflammation
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J. Dermatol. Sci., 2018;0(0):. 2018
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The BTK Inhibitor ARQ 531 Targets Ibrutinib Resistant CLL and Richter's Transformation
Authors: SD Reiff, R Mantel, LL Smith, JT Greene, EM Muhowski, CA Fabian, VM Goettl, M Tran, B Harrington, KA Rogers, FT Awan, K Maddocks, L Andritsos, AM Lehman, D Sampath, R Lapalombel, S Eathiraj, G Abbadessa, B Schwartz, A Johnson, JC Byrd, JA Woyach
Cancer Discov, 2018;0(0):. 2018
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Proteasomal degradation of NOD2 by NLRP12 in monocytes promotes bacterial tolerance and colonization by enteropathogens
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Nat Commun, 2018;9(1):5338. 2018
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Schwann cell-like differentiated adipose stem cells promote neurite outgrowth via secreted exosomes and RNA transfer
Authors: RC Ching, M Wiberg, PJ Kingham
Stem Cell Res Ther, 2018;9(1):266. 2018
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Cancer-associated fibroblasts suppress SOX2-induced dysplasia in a lung squamous cancer coculture
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Proc. Natl. Acad. Sci. U.S.A., 2018;115(50):E11671-E11680. 2018
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Contribution of three-dimensional architecture and tumor-associated fibroblasts to hepcidin regulation in breast cancer
Authors: N Blanchette, D Kita, A Konstorum, L Tesfay, D Lemler, P Hegde, KP Claffey, FM Torti, SV Torti
Oncogene, 2018;37(29):4013-4032. 2018
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The E3 ubiquitin ligase TRIM25 regulates adipocyte differentiation via proteasome-mediated degradation of PPAR?
Authors: JM Lee, SS Choi, YH Lee, KW Khim, S Yoon, BG Kim, D Nam, PG Suh, K Myung, JH Choi
Exp. Mol. Med., 2018;50(10):135. 2018
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High-resolution acoustophoretic 3D cell patterning to construct functional collateral cylindroids for ischemia therapy
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Nat Commun, 2018;9(1):5402. 2018
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Microenvironment-derived ADAM28 prevents cancer dissemination
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Oncotarget, 2018;9(98):37185-37199. 2018
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IL-1 and TGF-? Modulation of Epithelial Basement Membrane Components Perlecan and Nidogen Production by Corneal Stromal Cells
Authors: P Saikia, S Thangavadi, CS Medeiros, L Lassance, RC de Oliveir, SE Wilson
Invest. Ophthalmol. Vis. Sci., 2018;59(13):5589-5598. 2018
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Mouse Mast Cell Protease 4 Deletion Protects Heart Function and Survival After Permanent Myocardial Infarction
Authors: M Houde, A Schwertani, H Touil, L Desbiens, O Sarrhini, R Lecomte, M Lepage, H Gagnon, S Takai, G Pejler, D Jacques, F Gobeil, R Day, P D'Orléans-
Front Pharmacol, 2018;9(0):868. 2018
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IL-10 correlates with the expression of carboxypeptidase B2 and lymphovascular invasion in inflammatory breast cancer: The potential role of tumor infiltrated macrophages
Authors: HT Mohamed, N El-Hussein, EA El-Ghonaim, SA Ibrahim, ZA Bazzi, D Cavallo-Me, MB Boffa, M El-Shinawi, MM Mohamed
Curr Probl Cancer, 2018;0(0):. 2018
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CXCR4 Accelerates Osteoclastogenesis Induced by Non-Small Cell Lung Carcinoma Cells Through Self-Potentiation and VCAM1 Secretion
Authors: T Liao, W Chen, J Sun, Y Zhang, X Hu, S Yang, H Qiu, S Li, T Chu
Cell. Physiol. Biochem., 2018;50(3):1084-1099. 2018
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IL-25 promotes Th2 bias by upregulating IL-4 and IL-10 expression of decidual ??T cells in early pregnancy.
Authors: Yuan Zhang, Ying Wang, Ming-Qing Li, Jie Duan, Deng-Xuan Fan, Li-Ping Jin
Experimental and Therapeutic Medicine, 2018;0(0):1792-0981. 2018
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Injectable hydrogels of optimized acellular nerve for injection in the injured spinal cord
Authors: RC Cornelison, E Gonzalez-R, SL Porvasnik, SM Wellman, JH Park, DD Fuller, CE Schmidt
Biomed Mater, 2018;0(0):. 2018
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TGF-?-Induced CD8CD103Regulatory T Cells Show Potent Therapeutic Effect on Chronic Graft-versus-Host Disease Lupus by Suppressing B Cells
Authors: H Zhong, Y Liu, Z Xu, P Liang, H Yang, X Zhang, J Zhao, J Chen, S Fu, Y Tang, J Lv, J Wang, N Olsen, A Xu, SG Zheng
Front Immunol, 2018;9(0):35. 2018
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Telatinib is an effective targeted therapy for pseudomyogenic hemangioendothelioma
Authors: DGP van IJzend, S Sleijfer, H Gelderblom, FALM Eskens, GJ van Leende, K Szuhai, JVMG Bovee
Clin. Cancer Res., 2018;0(0):. 2018
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Circuit Design Features of a Stable Two-Cell System
Authors: X Zhou, RA Franklin, M Adler, JB Jacox, W Bailis, JA Shyer, RA Flavell, A Mayo, U Alon, R Medzhitov
Cell, 2018;172(4):744-757.e17. 2018
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The MtDMI2-MtPUB2 negative feedback loop plays a role in nodulation homeostasis
Authors: J Liu, J Deng, F Zhu, Y Li, Z Lu, P Qin, T Wang, J Dong
Plant Physiol., 2018;0(0):. 2018
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Metabolic Induction of Trained Immunity through the Mevalonate Pathway
Authors: S Bekkering, RJW Arts, B Novakovic, I Kourtzelis, CDCC van der He, Y Li, CD Popa, R Ter Horst, J van Tuijl, RT Netea-Maie, FL van de Vee, T Chavakis, LAB Joosten, JWM van der Me, H Stunnenber, NP Riksen, MG Netea
Cell, 2018;172(1):135-146.e9. 2018
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Targeting anticoagulant protein S to improve hemostasis in hemophilia
Authors: R Prince, L Bologna, M Manetti, D Melchiorre, I Rosa, N Dewarrat, S Suardi, P Amini, JA Fernández, L Burnier, C Quarroz, MD Reina Caro, Y Matsumura, JA Kremer Hov, JH Griffin, HU Simon, L Ibba-Manne, F Saller, S Calzavarin, A Angelillo-
Blood, 2018;0(0):. 2018
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Guidance of super-enhancers in regulation of IL-9 induction and airway inflammation
Authors: X Xiao, Y Fan, J Li, X Zhang, X Lou, Y Dou, X Shi, P Lan, Y Xiao, L Minze, XC Li
J. Exp. Med., 2018;0(0):. 2018
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Monocyte chemoattractant protein 1 and fractalkine play opposite roles in angiogenesisviarecruitment of different macrophage subtypes
Authors: L Chen, GQ Liu, HY Wu, J Jin, X Yin, D Li, PR Lu
Int J Ophthalmol, 2018;11(2):216-222. 2018
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PINK1 autophosphorylation is required for ubiquitin recognition
Authors: S Rasool, N Soya, L Truong, N Croteau, GL Lukacs, JF Trempe
EMBO Rep., 2018;0(0):. 2018
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Development of Versatile Human In Vitro Vascularized Adipose Tissue Model with Serum-Free Angiogenesis and Natural Adipogenesis Induction
Authors: O Huttala, M Palmroth, P Hemminki, T Toimela, T Heinonen, T Ylikomi, JR Sarkanen
Basic Clin. Pharmacol. Toxicol., 2018;0(0):. 2018
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Dynamic Ligand Discrimination in the Notch Signaling Pathway
Authors: N Nandagopal, LA Santat, L LeBon, D Sprinzak, ME Bronner, MB Elowitz
Cell, 2018;172(4):869-880.e19. 2018
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EphrinB2/EphB4 signaling regulates non-sprouting angiogenesis by VEGF
Authors: E Groppa, S Brkic, A Uccelli, G Wirth, P Korpisalo-, M Filippova, B Dasen, V Sacchi, MG Muraro, M Trani, S Reginato, R Gianni-Bar, S Ylä-Herttu, A Banfi
EMBO Rep., 2018;0(0):. 2018
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IL-23-induced macrophage polarization and its pathological roles in mice with imiquimod-induced psoriasis
Authors: Y Hou, L Zhu, H Tian, HX Sun, R Wang, L Zhang, Y Zhao
Protein Cell, 2018;0(0):. 2018
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Expression of mutant Asxl1 perturbs hematopoiesis and promotes susceptibility to leukemic transformation
Authors: R Nagase, D Inoue, A Pastore, T Fujino, HA Hou, N Yamasaki, S Goyama, M Saika, A Kanai, Y Sera, S Horikawa, Y Ota, S Asada, Y Hayashi, KC Kawabata, R Takeda, HF Tien, H Honda, O Abdel-Waha, T Kitamura
J. Exp. Med., 2018;0(0):. 2018
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TNFSF14 (LIGHT) Exhibits Inflammatory Activities in Lung Fibroblasts Complementary to IL-13 and TGF-β
Authors: R da Silva A, AK Mehta, L Madge, J Tocker, M Croft
Front Immunol, 2018;9(0):576. 2018
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Nanoscale Dynamism of Actin Enables Secretory Function in Cytolytic Cells
Authors: AF Carisey, EM Mace, MB Saeed, DM Davis, JS Orange
Curr. Biol., 2018;0(0):. 2018
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Downregulation of microRNA-448 inhibits IL-1?-induced cartilage degradation in human chondrocytes via upregulation of matrilin-3
Authors: H Yang, D Wu, H Li, N Chen, Y Shang
Cell. Mol. Biol. Lett., 2018;23(0):7. 2018
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Mesenchymal Wnt/?-catenin signaling limits tooth number
Authors: E Järvinen, J Shimomura-, A Balic, M Jussila, I Thesleff
Development, 2018;0(0):. 2018
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MicroRNA-31 is required for astrocyte specification
Authors: GP Meares, R Rajbhandar, M Gerigk, CL Tien, C Chang, SC Fehling, A Rowse, KC Mulhern, S Nair, GK Gray, NF Berbari, M Bredel, EN Benveniste, SE Nozell
Glia, 2018;0(0):. 2018
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Inducing Apoptosis and Decreasing Cell Proliferation in Human Acute Promyelocytic Leukemia Through Regulation Expression ofCASP3by Let-7a-5p Blockage
Authors: M Fasihi-Ram, A Moridnia, A Najafi, M Sharifi
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