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CometAssay 96-well Kit

Catalog #: 4253-096-K
166 Citations Datasheet / COA / SDS

Discontinued Product

4253-096-K has been discontinued.
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Citations (166)
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CometAssay 96-well Kit Summary

Includes one specially treated CometSlide (96 Well) and sufficient reagents to test 96 samples.
 

Key Benefits

• Specially treated slides to promote agarose adherence
• Ready to use low melt agarose (LMAgarose) in convenient size
• Lysis Solution suitable for either alkaline or neutral comet assay
• Optimized electrophoresis conditions

Applications for CometAssay 96-well Kit?

  • Applicable for the analysis of either single- or double-strand DNA breaks
  • Study cellular responses to DNA damage
  • Screen for inhibitors of DNA repair
  • Test chemicals for toxicity
  • Screen for environmental mutagens

Kit Contents

• CometAssay Lysis Solution
• CometAssay LMAgarose
• 200 mM EDTA, pH 10
• CometSlide (96 Well)

Specifications

Shipping Conditions
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended on the label.
Storage
Store the unopened product at room temperature. Do not use past expiration date.
Species
N/A

Limitations

For research use only. Not for diagnostic use.

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Citations for CometAssay 96-well Kit

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

166 Citations: Showing 1 - 10
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  1. Engineered Mesoporous Silica-Based Core-Shell Nanoarchitectures for Synergistic Chemo-Photodynamic Therapies
    Authors: YM Gao, SH Chiu, P Busa, CL Liu, RK Kankala, CH Lee
    International Journal of Molecular Sciences, 2022-10-01;23(19):.  2022-10-01
  2. Toxicity response to benzo[alpha]pyrene exposure: Modulation of immune parameters of the bay scallop, Argopectenirradians
    Authors: JA Song, KH Kho, YS Park, CY Choi
    Fish & shellfish immunology, 2022-04-27;124(0):505-512.  2022-04-27
  3. Evaluation of waterpipe smoke toxicity in C57BL/6 mice model
    Authors: A Abi-Gerges, C Dagher-Ham, P Abou-Khali, JB Chahine, P Hachem, C Khalil
    Pulm Pharmacol Ther, 2020-09-02;63(0):101940.  2020-09-02
  4. The multiplex interactions and molecular mechanism on genotoxicity induced by formaldehyde and acrolein mixtures on human bronchial epithelial BEAS-2B cells
    Authors: S Zhang, H Chen, J Zhang, J Li, H Hou, Q Hu
    Environ Int, 2020-07-10;143(0):105943.  2020-07-10
  5. ATAD5 deficiency alters DNA damage metabolism and sensitizes cells to PARP inhibition
    Authors: S Giovannini, MC Weller, H Hanzlíková, T Shiota, S Takeda, J Jiricny
    Nucleic Acids Res., 2020-05-21;0(0):.  2020-05-21
  6. Norepinephrine-Induced DNA Damage in Ovarian Cancer Cells
    Authors: R Lamboy-Car, C Ortiz-Sanc, A Acevedo-Sa, J Matta, A N A Montei, G N Armaiz-P
    Int J Mol Sci, 2020-03-24;21(6):.  2020-03-24
  7. Self assembled dual responsive micelles stabilized with protein for co-delivery of drug and siRNA in cancer therapy.
    Authors: Aji Alex M, Nehate C, Veeranarayanan S, Kumar D, Kulshreshtha R, Koul V
    Biomaterials, 2017-04-17;133(0):94-106.  2017-04-17
  8. Development of a Test Method for the Evaluation of DNA Damage in Mouse Spermatogonial Stem Cells.
    Authors: Jeon H, Yi J, Kim T, Oh Y, Lee H, Lee M, Bang J, Ko K, Ahn I, Ko K, Kim J, Park H, Lee J, Sohn S
    Toxicol Res, 2017-04-15;33(2):107-118.  2017-04-15
  9. Aspirin inhibits the SHH/GLI1 signaling pathway and sensitizes malignant glioma cells to temozolomide therapy.
    Authors: Ming J, Sun B, Li Z, Lin L, Meng X, Han B, Wang R, Wu P, Li J, Cai J, Jiang C
    Aging (Albany NY), 2017-04-01;9(4):1233-1247.  2017-04-01
  10. miR-101 Enhances Cisplatin-Induced DNA Damage Through Decreasing Nicotinamide Adenine Dinucleotide Phosphate Levels by Directly Repressing Tp53-Induced Glycolysis and Apoptosis Regulator Expression in Prostate Cancer Cells.
    Authors: Huang S, Yang Z, Ma Y, Yang Y, Wang S
    DNA Cell Biol, 2017-04-01;36(4):303-310.  2017-04-01
  11. Glucocorticoids induce production of reactive oxygen species/reactive nitrogen species and DNA damage through an iNOS mediated pathway in breast cancer.
    Authors: Flaherty R, Owen M, Fagan-Murphy A, Intabli H, Healy D, Patel A, Allen M, Patel B, Flint M
    Breast Cancer Res, 2017-03-24;19(1):35.  2017-03-24
  12. Sirt6 Promotes DNA End Joining in iPSCs Derived from Old Mice.
    Authors: Chen W, Liu N, Zhang H, Zhang H, Qiao J, Jia W, Zhu S, Mao Z, Kang J
    Cell Rep, 2017-03-21;18(12):2880-2892.  2017-03-21
  13. RUG3 and ATM synergistically regulate the alternative splicing of mitochondrial nad2 and the DNA damage response in Arabidopsis thaliana.
    Authors: Su C, Zhao H, Zhao Y, Ji H, Wang Y, Zhi L, Li X
    Sci Rep, 2017-03-06;7(0):43897.  2017-03-06
  14. Doxorubicin and vincristine affect undifferentiated rat spermatogonia.
    Authors: Beaud H, van Pelt A, Delbes G
    Reproduction, 2017-03-03;153(6):725-735.  2017-03-03
  15. Stimulation of lactate receptor (HCAR1) affects cellular DNA repair capacity.
    Authors: Wagner W, Kania K, Ciszewski W
    DNA Repair (Amst), 2017-02-20;52(0):49-58.  2017-02-20
  16. Cytidine deaminase Apobec3a induction in fallopian epithelium after exposure to follicular fluid.
    Authors: Brachova P, Alvarez N, Van Voorhis B, Christenson L
    Gynecol Oncol, 2017-02-16;145(3):577-583.  2017-02-16
  17. Ubiquitylation of Ku80 by RNF126 Promotes Completion of Nonhomologous End Joining-Mediated DNA Repair.
    Authors: Ishida N, Nakagawa T, Iemura S, Yasui A, Shima H, Katoh Y, Nagasawa Y, Natsume T, Igarashi K, Nakayama K
    Mol Cell Biol, 2017-02-01;37(4):.  2017-02-01
  18. FOXO3 Transcription Factor Is Essential for Protecting Hematopoietic Stem and Progenitor Cells from Oxidative DNA Damage.
    Authors: Bigarella C, Li J, Rimmele P, Liang R, Sobol R, Ghaffari S
    J Biol Chem, 2016-12-19;292(7):3005-3015.  2016-12-19
  19. A nuclease that mediates cell death induced by DNA damage and poly(ADP-ribose) polymerase-1.
    Authors: Wang Y, An R, Umanah G, Park H, Nambiar K, Eacker S, Kim B, Bao L, Harraz M, Chang C, Chen R, Wang J, Kam T, Jeong J, Xie Z, Neifert S, Qian J, Andrabi S, Blackshaw S, Zhu H, Song H, Ming G, Dawson V, Dawson T
    Science, 2016-10-07;354(6308):.  2016-10-07
  20. Distribution, quantification and toxicity of cinnamaldehyde in electronic cigarette refill fluids and aerosols.
    Authors: Behar R, Luo W, Lin S, Wang Y, Valle J, Pankow J, Talbot P
    Tob Control, 2016-09-15;25(0):ii94-ii102.  2016-09-15
  21. Lurbinectedin Specifically Triggers the Degradation of Phosphorylated RNA Polymerase II and the Formation of DNA Breaks in Cancer Cells.
    Authors: Santamaria Nunez G, Robles C, Giraudon C, Martinez-Leal J, Compe E, Coin F, Aviles P, Galmarini C, Egly J
    Mol Cancer Ther, 2016-09-14;15(10):2399-2412.  2016-09-14
  22. Special AT-rich Sequence-binding Protein 1 (SATB1) Functions as an Accessory Factor in Base Excision Repair.
    Authors: Kaur S, Coulombe Y, Ramdzan Z, Leduy L, Masson J, Nepveu A
    J Biol Chem, 2016-09-02;291(43):22769-22780.  2016-09-02
  23. A role for the p53 tumour suppressor in regulating the balance between homologous recombination and non-homologous end joining.
    Authors: Moureau S, Luessing J, Harte E, Voisin M, Lowndes N
    Open Biol, 2016-09-01;6(9):.  2016-09-01
  24. Amplification of TLK2 Induces Genomic Instability via Impairing the G2-M Checkpoint.
    Authors: Kim J, Anurag M, Veeraraghavan J, Schiff R, Li K, Wang X
    Mol Cancer Res, 2016-08-03;14(10):920-927.  2016-08-03
  25. DNA Damage Response and DNA Repair in Skeletal Myocytes From a Mouse Model of Spinal Muscular Atrophy.
    Authors: Fayzullina S, Martin L
    J Neuropathol Exp Neurol, 2016-07-24;75(9):889-902.  2016-07-24
  26. Human CDK18 promotes replication stress signaling and genome stability.
    Authors: Barone G, Staples C, Ganesh A, Patterson K, Bryne D, Myers K, Patil A, Eyers C, Maslen S, Skehel J, Eyers P, Collis S
    Nucleic Acids Res, 2016-07-05;44(18):8772-8785.  2016-07-05
  27. Overexpression of HPV16 E6* Alters beta-Integrin and Mitochondrial Dysfunction Pathways in Cervical Cancer Cells.
    Authors: Evans W, Filippova M, Filippov V, Bashkirova S, Zhang G, Reeves M, Duerksen-Hughes P
    Cancer Genomics Proteomics, 2016-07-01;13(4):259-73.  2016-07-01
  28. HOXC10 Expression Supports the Development of Chemotherapy Resistance by Fine Tuning DNA Repair in Breast Cancer Cells.
    Authors: Sadik H, Korangath P, Nguyen N, Gyorffy B, Kumar R, Hedayati M, Teo W, Park S, Panday H, Munoz T, Menyhart O, Shah N, Pandita R, Chang J, Deweese T, Chang H, Pandita T, Sukumar S
    Cancer Res, 2016-06-14;76(15):4443-56.  2016-06-14
  29. Triplex structures induce DNA double strand breaks via replication fork collapse in NER deficient cells.
    Authors: Kaushik Tiwari M, Adaku N, Peart N, Rogers F
    Nucleic Acids Res, 2016-06-13;44(16):7742-54.  2016-06-13
  30. PKCalpha and HMGB1 antagonistically control hydrogen peroxide-induced poly-ADP-ribose formation.
    Authors: Andersson A, Bluwstein A, Kumar N, Teloni F, Traenkle J, Baudis M, Altmeyer M, Hottiger M
    Nucleic Acids Res, 2016-05-19;44(16):7630-45.  2016-05-19
  31. Methylation of histone H4 lysine 20 by PR-Set7 ensures the integrity of late replicating sequence domains in Drosophila.
    Authors: Li Y, Armstrong R, Duronio R, MacAlpine D
    Nucleic Acids Res, 2016-04-29;44(15):7204-18.  2016-04-29
  32. NQO1-Mediated Tumor-Selective Lethality and Radiosensitization for Head and Neck Cancer.
    Authors: Li L, Reddy S, Lin Z, Liu S, Park H, Chun S, Bornmann W, Thibodeaux J, Yan J, Chakrabarti G, Xie X, Sumer B, Boothman D, Yordy J
    Mol Cancer Ther, 2016-04-12;15(7):1757-67.  2016-04-12
  33. A ubiquitylation site in Cockayne syndrome B required for repair of oxidative DNA damage, but not for transcription-coupled nucleotide excision repair.
    Authors: Ranes M, Boeing S, Wang Y, Wienholz F, Menoni H, Walker J, Encheva V, Chakravarty P, Mari P, Stewart A, Giglia-Mari G, Snijders A, Vermeulen W, Svejstrup J
    Nucleic Acids Res, 2016-04-07;44(11):5246-55.  2016-04-07
  34. A panel of in vitro tests to evaluate genotoxic and morphological neoplastic transformation potential on Balb/3T3 cells by pristine and remediated titania and zirconia nanoparticles.
    Authors: Stoccoro A, Di Bucchianico S, Uboldi C, Coppede F, Ponti J, Placidi C, Blosi M, Ortelli S, Costa A, Migliore L
    Mutagenesis, 2016-04-07;31(5):511-29.  2016-04-07
  35. Long noncoding RNA POU6F2-AS2 is associated with oesophageal squamous cell carcinoma.
    Authors: Liu J, Sun X, Zhu H, Qin Q, Yang X, Sun X
    J Biochem, 2016-03-31;160(4):195-204.  2016-03-31
  36. HT-COMET: a novel automated approach for high throughput assessment of human sperm chromatin quality.
    Authors: Albert O, Reintsch W, Chan P, Robaire B
    Hum Reprod, 2016-03-13;31(5):938-46.  2016-03-13
  37. Differences in quantification of DNA double-strand breaks assessed by 53BP1/gammaH2AX focus formation assays and the comet assay in mammalian cells treated with irradiation and N-acetyl-L-cysteine.
    Authors: Kurashige T, Shimamura M, Nagayama Y
    J Radiat Res, 2016-03-06;57(3):312-7.  2016-03-06
  38. Unique epigenetic influence of H2AX phosphorylation and H3K56 acetylation on normal stem cell radioresponses.
    Authors: Jacobs K, Misri S, Meyer B, Raj S, Zobel C, Sleckman B, Hallahan D, Sharma G
    Mol Biol Cell, 2016-03-03;27(8):1332-45.  2016-03-03
  39. Disruption of DNA Damage-Response by Propyl Gallate and 9-Aminoacridine.
    Authors: Matsuda S, Matsuda Y, Yanagisawa S, Ikura M, Ikura T, Matsuda T
    Toxicol Sci, 2016-02-28;151(2):224-35.  2016-02-28
  40. Characterizing Requirements for Small Ubiquitin-like Modifier (SUMO) Modification and Binding on Base Excision Repair Activity of Thymine-DNA Glycosylase in Vivo.
    Authors: McLaughlin D, Coey C, Yang W, Drohat A, Matunis M
    J Biol Chem, 2016-02-25;291(17):9014-24.  2016-02-25
  41. Effects of corexit oil dispersants and the WAF of dispersed oil on DNA damage and repair in cultured human bronchial airway cells, BEAS-2B.
    Authors: Major D, Derbes R, Wang H, Roy-Engel A
    Gene Rep, 2016-02-11;3(0):22-30.  2016-02-11
  42. miR-155 Overexpression Promotes Genomic Instability by Reducing High-fidelity Polymerase Delta Expression and Activating Error-Prone DSB Repair.
    Authors: Czochor J, Sulkowski P, Glazer P
    Mol Cancer Res, 2016-02-05;14(4):363-73.  2016-02-05
  43. Androgen Deprivation Followed by Acute Androgen Stimulation Selectively Sensitizes AR-Positive Prostate Cancer Cells to Ionizing Radiation.
    Authors: Hedayati M, Haffner M, Coulter J, Raval R, Zhang Y, Zhou H, Mian O, Knight E, Razavi N, Dalrymple S, Isaacs J, Santos A, Hales R, Nelson W, Yegnasubramanian S, Deweese T
    Clin Cancer Res, 2016-02-01;22(13):3310-3319.  2016-02-01
  44. Sequential Combination Therapy of CDK Inhibition and Doxorubicin Is Synthetically Lethal in p53-Mutant Triple-Negative Breast Cancer.
    Authors: Jabbour-Leung N, Chen X, Bui T, Jiang Y, Yang D, Vijayaraghavan S, McArthur M, Hunt K, Keyomarsi K
    Mol Cancer Ther, 2016-01-29;15(4):593-607.  2016-01-29
  45. DNA double-strand break repair: a theoretical framework and its application.
    Authors: Murray P, Cornelissen B, Vallis K, Chapman S
    J R Soc Interface, 2016-01-27;13(114):20150679.  2016-01-27
  46. The Opposing Actions of Arabidopsis CHROMOSOME TRANSMISSION FIDELITY7 and WINGS APART-LIKE1 and 2 Differ in Mitotic and Meiotic Cells.
    Authors: De K, Bolanos-Villegas P, Mitra S, Yang X, Homan G, Jauh G, Makaroff C
    Plant Cell, 2016-01-26;28(2):521-36.  2016-01-26
  47. The Role of HMGB1 in Radioresistance of Bladder Cancer.
    Authors: Shrivastava S, Mansure J, Almajed W, Cury F, Ferbeyre G, Popovic M, Seuntjens J, Kassouf W
    Mol Cancer Ther, 2015-12-30;15(3):471-9.  2015-12-30
  48. DNA-PK triggers histone ubiquitination and signaling in response to DNA double-strand breaks produced during the repair of transcription-blocking topoisomerase I lesions.
    Authors: Cristini A, Park J, Capranico G, Legube G, Favre G, Sordet O
    Nucleic Acids Res, 2015-11-17;0(0):.  2015-11-17
  49. UV Damage-Induced Phosphorylation of HBO1 Triggers CRL4DDB2-Mediated Degradation To Regulate Cell Proliferation.
    Authors: Matsunuma R, Niida H, Ohhata T, Kitagawa K, Sakai S, Uchida C, Shiotani B, Matsumoto M, Nakayama K, Ogura H, Shiiya N, Kitagawa M
    Mol Cell Biol, 2015-11-16;36(3):394-406.  2015-11-16
  50. Linking Cancer Metabolism to DNA Repair and Accelerated Senescence.
    Authors: Efimova E, Takahashi S, Shamsi N, Wu D, Labay E, Ulanovskaya O, Weichselbaum R, Kozmin S, Kron S
    Mol Cancer Res, 2015-11-04;14(2):173-84.  2015-11-04
  51. Requirement for human Mps1/TTK in oxidative DNA damage repair and cell survival through MDM2 phosphorylation.
    Authors: Yu Z, Huang Y, Shieh S
    Nucleic Acids Res, 2015-11-03;44(3):1133-50.  2015-11-03
  52. Targeting HGF/c-MET induces cell cycle arrest, DNA damage, and apoptosis for primary effusion lymphoma.
    Authors: Dai L, Trillo-Tinoco J, Cao Y, Bonstaff K, Doyle L, Del Valle L, Whitby D, Parsons C, Reiss K, Zabaleta J, Qin Z
    Blood, 2015-11-03;126(26):2821-31.  2015-11-03
  53. Long-term exposure to diesel engine exhaust induces primary DNA damage: a population-based study.
    Authors: Duan H, Jia X, Zhai Q, Ma L, Wang S, Huang C, Wang H, Niu Y, Li X, Dai Y, Yu S, Gao W, Chen W, Zheng Y
    Occup Environ Med, 2015-10-21;73(2):83-90.  2015-10-21
  54. c-Myc-miR-29c-REV3L signalling pathway drives the acquisition of temozolomide resistance in glioblastoma.
    Authors: Luo H, Chen Z, Wang S, Zhang R, Qiu W, Zhao L, Peng C, Xu R, Chen W, Wang H, Chen Y, Yang J, Zhang X, Zhang S, Chen D, Wu W, Zhao C, Cheng G, Jiang T, Lu D, You Y, Liu N, Wang H
    Brain, 2015-10-08;138(0):3654-72.  2015-10-08
  55. Environmentally Relevant Concentrations of Arsenite Induce Dose-Dependent Differential Genotoxicity Through Poly(ADP-Ribose) Polymerase Inhibition and Oxidative Stress in Mouse Thymus Cells.
    Authors: Xu H, Zhou X, Wen X, Lauer F, Liu K, Hudson L, Aleksunes L, Burchiel S
    Toxicol Sci, 2015-10-05;149(1):31-41.  2015-10-05
  56. Cytokine overproduction and crosslinker hypersensitivity are unlinked in Fanconi anemia macrophages.
    Authors: Garbati M, Hays L, Rathbun R, Jillette N, Chin K, Al-Dhalimy M, Agarwal A, Newell A, Olson S, Bagby G
    J Leukoc Biol, 2015-10-02;99(3):455-65.  2015-10-02
  57. ATDC (Ataxia Telangiectasia Group D Complementing) Promotes Radioresistance through an Interaction with the RNF8 Ubiquitin Ligase.
    Authors: Yang H, Palmbos P, Wang L, Kim E, Ney G, Liu C, Prasad J, Misek D, Yu X, Ljungman M, Simeone D
    J Biol Chem, 2015-09-17;290(45):27146-57.  2015-09-17
  58. Intracellular accumulation of indium ions released from nanoparticles induces oxidative stress, proinflammatory response and DNA damage.
    Authors: Tabei Y, Sonoda A, Nakajima Y, Biju V, Makita Y, Yoshida Y, Horie M
    J Biochem, 2015-09-15;159(2):225-37.  2015-09-15
  59. MERIT40 cooperates with BRCA2 to resolve DNA interstrand cross-links.
    Authors: Jiang Q, Paramasivam M, Aressy B, Wu J, Bellani M, Tong W, Seidman M, Greenberg R
    Genes Dev, 2015-09-03;29(18):1955-68.  2015-09-03
  60. The NEK1 interactor, C21ORF2, is required for efficient DNA damage repair.
    Authors: Fang X, Lin H, Wang X, Zuo Q, Qin J, Zhang P
    Acta Biochim Biophys Sin (Shanghai), 2015-08-18;47(10):834-41.  2015-08-18
  61. Stem Cell-Soluble Signals Enhance Multilumen Formation in SMG Cell Clusters.
    Authors: Maruyama C, Leigh N, Nelson J, McCall A, Mellas R, Lei P, Andreadis S, Baker O
    J Dent Res, 2015-08-18;94(11):1610-7.  2015-08-18
  62. Role of the Exocyst Complex Component Sec6/8 in Genomic Stability.
    Authors: Torres M, Pandita R, Kulak O, Kumar R, Formstecher E, Horikoshi N, Mujoo K, Hunt C, Zhao Y, Lum L, Zaman A, Yeaman C, White M, Pandita T
    Mol Cell Biol, 2015-08-17;35(21):3633-45.  2015-08-17
  63. Cdc14A and Cdc14B Redundantly Regulate DNA Double-Strand Break Repair.
    Authors: Lin H, Ha K, Lu G, Fang X, Cheng R, Zuo Q, Zhang P
    Mol Cell Biol, 2015-08-17;35(21):3657-68.  2015-08-17
  64. Depletion of the chromatin remodeler CHD4 sensitizes AML blasts to genotoxic agents and reduces tumor formation.
    Authors: Sperlazza J, Rahmani M, Beckta J, Aust M, Hawkins E, Wang S, Zu Zhu S, Podder S, Dumur C, Archer K, Grant S, Ginder G
    Blood, 2015-08-11;126(12):1462-72.  2015-08-11
  65. hSSB1 (NABP2/ OBFC2B) is required for the repair of 8-oxo-guanine by the hOGG1-mediated base excision repair pathway.
    Authors: Paquet N, Adams M, Leong V, Ashton N, Touma C, Gamsjaeger R, Cubeddu L, Beard S, Burgess J, Bolderson E, O'Byrne K, Richard D
    Nucleic Acids Res, 2015-08-10;43(18):8817-29.  2015-08-10
  66. Ablation of XP-V gene causes adipose tissue senescence and metabolic abnormalities.
    Authors: Chen Y, Harris R, Hatahet Z, Chou K
    Proc Natl Acad Sci U S A, 2015-08-03;112(33):E4556-64.  2015-08-03
  67. CUX2 protein functions as an accessory factor in the repair of oxidative DNA damage.
    Authors: Pal R, Ramdzan Z, Kaur S, Duquette P, Marcotte R, Leduy L, Davoudi S, Lamarche-Vane N, Iulianella A, Nepveu A
    J Biol Chem, 2015-07-28;290(37):22520-31.  2015-07-28
  68. PKR inhibits the DNA damage response, and is associated with poor survival in AML and accelerated leukemia in NHD13 mice.
    Authors: Cheng X, Byrne M, Brown K, Konopleva M, Kornblau S, Bennett R, May W
    Blood, 2015-07-22;126(13):1585-94.  2015-07-22
  69. Gold nanostars mediated combined photothermal and photodynamic therapy and X-ray imaging for cancer theranostic applications.
    Authors: Wang L, Meng D, Hao Y, Zhao Y, Li D, Zhang B, Zhang Y, Zhang Z
    J Biomater Appl, 2015-07-21;30(5):547-57.  2015-07-21
  70. YU238259 Is a Novel Inhibitor of Homology-Dependent DNA Repair That Exhibits Synthetic Lethality and Radiosensitization in Repair-Deficient Tumors.
    Authors: Stachelek G, Peterson-Roth E, Liu Y, Fernandez R, Pike L, Qian J, Abriola L, Hoyer D, Hungerford W, Merkel J, Glazer P
    Mol Cancer Res, 2015-06-26;13(10):1389-97.  2015-06-26
  71. Engineered cellular gene-replacement platform for selective and inducible proteolytic profiling.
    Authors: Morgan C, Diaz J, Zeitlin S, Gray D, Wells J
    Proc Natl Acad Sci U S A, 2015-06-23;112(27):8344-9.  2015-06-23
  72. USP1 targeting impedes GBM growth by inhibiting stem cell maintenance and radioresistance.
    Authors: Lee J, Chang N, Yoon Y, Yang H, Cho H, Kim E, Shin Y, Kang W, Oh Y, Mun G, Joo K, Nam D, Lee J
    Neuro Oncol, 2015-06-01;18(1):37-47.  2015-06-01
  73. The TMPRSS2-ERG Gene Fusion Blocks XRCC4-Mediated Nonhomologous End-Joining Repair and Radiosensitizes Prostate Cancer Cells to PARP Inhibition.
    Authors: Chatterjee P, Choudhary G, Alswillah T, Xiong X, Heston W, Magi-Galluzzi C, Zhang J, Klein E, Almasan A
    Mol Cancer Ther, 2015-05-29;14(8):1896-906.  2015-05-29
  74. Repair of DNA Damage Induced by the Cytidine Analog Zebularine Requires ATR and ATM in Arabidopsis.
    Authors: Liu C, Finke A, Diaz M, Rozhon W, Poppenberger B, Baubec T, Pecinka A
    Plant Cell, 2015-05-28;27(6):1788-800.  2015-05-28
  75. Ghrelin Prevents Cisplatin-Induced Testicular Damage by Facilitating Repair of DNA Double Strand Breaks Through Activation of p53 in Mice.
    Authors: Garcia J, Chen J, Guillory B, Donehower L, Smith R, Lamb D
    Biol Reprod, 2015-05-27;93(1):24.  2015-05-27
  76. Augmentation of response to chemotherapy by microRNA-506 through regulation of RAD51 in serous ovarian cancers.
    Authors: Liu G, Yang D, Rupaimoole R, Pecot C, Sun Y, Mangala L, Li X, Ji P, Cogdell D, Hu L, Wang Y, Rodriguez-Aguayo C, Lopez-Berestein G, Shmulevich I, De Cecco L, Chen K, Mezzanzanica D, Xue F, Sood A, Zhang W
    J Natl Cancer Inst, 2015-05-20;107(7):.  2015-05-20
  77. Macrophages Regulate the Systemic Response to DNA Damage by a Cell Nonautonomous Mechanism.
    Authors: Geiger-Maor A, Guedj A, Even-Ram S, Smith Y, Galun E, Rachmilewitz J
    Cancer Res, 2015-05-14;75(13):2663-73.  2015-05-14
  78. Silver nanoparticles: correlating nanoparticle size and cellular uptake with genotoxicity.
    Authors: Butler K, Peeler D, Casey B, Dair B, Elespuru R
    Mutagenesis, 2015-05-11;30(4):577-91.  2015-05-11
  79. Repair versus Checkpoint Functions of BRCA1 Are Differentially Regulated by Site of Chromatin Binding.
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  90. Replication fork integrity and intra-S phase checkpoint suppress gene amplification.
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  92. Nuclear GIT2 is an ATM substrate and promotes DNA repair.
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  101. Damaging legacy: maternal cigarette smoking has long-term consequences for male offspring fertility.
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  102. Innate inflammation induced by the 8-oxoguanine DNA glycosylase-1-KRAS-NF-kappaB pathway.
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  105. HTLV-1 bZIP factor HBZ promotes cell proliferation and genetic instability by activating OncomiRs.
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  106. Homologous recombination repair signaling in chemical carcinogenesis: prolonged particulate hexavalent chromium exposure suppresses the Rad51 response in human lung cells.
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  109. Connexin 30 expression inhibits growth of human malignant gliomas but protects them against radiation therapy.
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  110. Potential for genomic instability associated with retrotranspositionally-incompetent L1 loci.
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  113. Sequential combination therapy of ovarian cancer with degradable N-(2-hydroxypropyl)methacrylamide copolymer paclitaxel and gemcitabine conjugates.
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  116. Tobacco exposure results in increased E6 and E7 oncogene expression, DNA damage and mutation rates in cells maintaining episomal human papillomavirus 16 genomes.
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  117. NEO212, temozolomide conjugated to perillyl alcohol, is a novel drug for effective treatment of a broad range of temozolomide-resistant gliomas.
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  118. CRL4Cdt2 E3 ubiquitin ligase and proliferating cell nuclear antigen (PCNA) cooperate to degrade thymine DNA glycosylase in S phase.
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  119. ATM regulates NF-kappaB-dependent immediate-early genes via RelA Ser 276 phosphorylation coupled to CDK9 promoter recruitment.
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  120. RhoB promotes gammaH2AX dephosphorylation and DNA double-strand break repair.
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  121. Developmental expression of Musashi-1 and Musashi-2 RNA-binding proteins during spermatogenesis: analysis of the deleterious effects of dysregulated expression.
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  122. Human single-stranded DNA binding protein 1 (hSSB1/NABP2) is required for the stability and repair of stalled replication forks.
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  123. Role of intracellular calcium and NADPH oxidase NOX5-S in acid-induced DNA damage in Barrett's cells and Barrett's esophageal adenocarcinoma cells.
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  124. Human papillomavirus type 16 E6* induces oxidative stress and DNA damage.
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  126. Hypoxic stress facilitates acute activation and chronic downregulation of fanconi anemia proteins.
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  127. Nedd8-activating enzyme inhibitor MLN4924 provides synergy with mitomycin C through interactions with ATR, BRCA1/BRCA2, and chromatin dynamics pathways.
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  129. Kub5-Hera, the human Rtt103 homolog, plays dual functional roles in transcription termination and DNA repair.
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  133. Unbiased compound screening identifies unexpected drug sensitivities and novel treatment options for gastrointestinal stromal tumors.
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  139. Lobarstin enhances chemosensitivity in human glioblastoma T98G cells.
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  141. Potential new mechanisms of placental damage in celiac disease: anti-transglutaminase antibodies impair human endometrial angiogenesis.
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