Compstatin control peptide

Biological Activity

Active Analog also available.

Technical Data

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Background References

1. Complement component C3 mediates Th1/Th17 polarization in human T-cell activation and cutaneous GVHD.
   Ma Q, Li D, Carreno R, Patenia R, Tsai K, Xydes-Smith M, Alousi A, Champlin R, Sale G, Afshar-Kharghan V
   Bone Marrow Transplant, 2014;49(7):972-6.
2. Inhibition of human complement by a C3-binding peptide isolated from a phage-displayed random peptide library.
   Sahu et al.
   J.Immunol., 1996;157:884
3. Compstatin, a peptide inhibitor of C3, prolongs survival of ex vivo perfused pig xenografts.
   Fiane et al.
   Xenotransplantation, 1999;6:52
4. Essential role of the C5a receptor in E coli-induced oxidative burst and phagocytosis revealed by a novel lepirudin-based human whole blood model of inflammation.
   Mollnes et al.
   Blood, 2002;100:1869

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