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Cyclapolin 9

Catalog #: 3116
1 Citation Datasheet / COA / SDS

Discontinued Product

3116 has been discontinued.
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Cyclapolin 9 | CAS No. 40533-25-3 | Polo-like Kinase Inhibitors
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Description: Selective, ATP-competitive PLK1 inhibitor

Chemical Name: 7-Nitro-5-(trifluoromethyl)-2-benzothiazolecarboxamide-3-oxide

Purity: ≥98%

Product Details
Citations (1)
Reviews
Biological Activity Technical Data Background Product Datasheets Calculators

Biological Activity

Cyclapolin 9 is a selective, ATP-competitive polo-like kinase 1 (PLK1) inhibitor (IC50 = 500 nM).

Technical Data

M.Wt:
307.21
Formula:
C9H4F3N3O4S
Solubility:
Soluble to 25 mM in DMSO and to 10 mM in ethanol
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
40533-25-3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Ligand discovery and virtual screening using the program LIDAEUS.
    Taylor et al.
    Br.J.Pharmacol., 2008;153:S55
  2. Inhibitors of polo-like kinase reveal roles in spindle pole maintenance.
    McInnes et al.
    Nature Chem.Biol., 2006;2:608

Product Datasheets

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Reconstitution Calculator

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Citation for Cyclapolin 9

The citations listed below are publications that use Tocris products. Selected citations for Cyclapolin 9 include:

1 Citation: Showing 1 - 1

  1. Nucleus accumbens mGluR5-associated signaling regulates binge alcohol drinking under drinking-in-the-dark procedures.
    Authors: Cozzoli Et al.
    Proc Natl Acad Sci U S A  2012;36:1623

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