D-myo-Inositol 1,4,5-trisphosphate, hexapotassium salt
Biological Activity
D-myo-Inositol 1,4,5-trisphosphate, hexapotassium salt is an important second messenger involved in Ca2+ mobilization from intracellular stores (EC50 = 0.1 μM). Formed from the enzymatic hydrolysis of phosphatidyl inositol-4,5-bisphosphate.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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myo-Inositol 1,4,5-trisphosphate.
Joseph et al.
J.Biol.Chem., 1984;259:3077 -
Enantiomers of myo-inositol-1,3,4-trisphosphate and myo-inositol-1,4,6-trisphosphate: stereospecific recognition by cerebellar and platelet myo-inositol-1,4,5-trisphosphate receptors.
Murphy et al.
Mol.Pharmacol., 1996;50:1223 -
New developments in the molecular pharmacology of the myo-inositol 1,4,5-trisphosphate receptor.
Wilcox et al.
TiPS, 1998;19:467
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Citation for D-myo-Inositol 1,4,5-trisphosphate, hexapotassium salt
The citations listed below are publications that use Tocris products. Selected citations for D-myo-Inositol 1,4,5-trisphosphate, hexapotassium salt include:
1 Citation: Showing 1 - 1
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Junctophilin 3 expresses in pancreatic beta cells and is required for glucose-stimulated Ins secretion.
Authors: Li Et al.
Cell Death Dis 2016;7:e2275
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