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(D)-(+)-Neopterin

Catalog #: 4656
1 Citation Datasheet / COA / SDS

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(D)-(+)-Neopterin | CAS No. 2009-64-5 | Cytokine Compounds
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Description: Stimulated by IFN-γ; marker of immune activation

Chemical Name: 2-Amino-6-[(1S,2R)-1,2,3-trihydroxypropyl]-4(3H)-pteridinone

Purity: ≥98%

Product Details
Citations (1)
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Biological Activity

(D)-(+)-Neopterin is a precursor of biopterin synthesis. Synthesized in response to interferon-γ stimulation; used as a marker of T helper cell-induced immune activation. Also an indicator of oxidative stress; modulates the effects of reactive oxygen species (ROS).

Technical Data

M.Wt:
253.21
Formula:
C9H11N5O4
Solubility:
Soluble to 20 mM in DMSO with gentle warming
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
2009-64-5

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Neopterin as a marker for immune system activation.
    Murr et al.
    Curr.Drug Metab., 2002;3:175
  2. Immune response-associated production of neopterin.
    Huber et al.
    J.Exp.Med., 1984;160:310

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Citation for (D)-(+)-Neopterin

The citations listed below are publications that use Tocris products. Selected citations for (D)-(+)-Neopterin include:

1 Citation: Showing 1 - 1

  1. Highly efficient SERS-based detection of cerebrospinal fluid neopterin as a diagnostic marker of bacterial infection.
    Authors: Kaminska Et al.
    J Neurochem  2016;408:4319

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