DBHDA
Chemical Name: 2,5-Dibromohexanediamide
Biological Activity
DBHDA is a reagent for synthetic biology; converts cysteine to dehydroalanine (Dha).Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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Methods for converting cysteine to dehydroalanine on peptides and proteins.
Chalker et al.
Chem. Sci., 2011;2:1666 -
Posttranslational mutagenesis: a chemical strategy for exploring protein side-chain diversity.
Wright et al.
Science, 2016;354:1465 -
A cascading activity-based probe sequentially targets E1-E2-E3 ubiquitin enzymes.
Mulder et al.
Nat.Chem.Biol., 2016;12:523 -
Generation of a synthetic GlcNAcylated nucleosome reveals regulation of stability by H2A-Thr101 GlcNAcylation.
Lercher et al.
Nat.Commun., 2015;25:7978
Product Datasheets
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Citation for DBHDA
The citations listed below are publications that use Tocris products. Selected citations for DBHDA include:
1 Citation: Showing 1 - 1
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Posttranslational, site-directed photochemical fluorine editing of protein sidechains to probe residue oxidation state via 19F-nuclear magnetic resonance.
Authors: Andrew J Et al.
Nat Protoc 2023;18:1543-1562
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