Home / Free Fatty Acid Receptor Antagonists / DC 260126

DC 260126

Catalog #: 5357 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
5357/50
5357/10
DC 260126 | CAS No. 346692-04-4 | Free Fatty Acid Receptor Antagonists
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Description: FFA1 (GPR40) antagonist

Chemical Name: N-(4-Butylphenyl)-4-fluorobenzenesulfonamide

Purity: ≥98%

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Biological Activity

DC 260126 is a free fatty acid receptor 1 (FFA1/GPR40) antagonist. Inhibits FFA-induced increases in intracellular Ca2+ levels and suppresses palmitic acid potentiated glucose-stimulated insulin secretion in Min6 pancreatic β cells in vitro. Decreases serum insulin levels, improves insulin sensitivity and reduces the number of apoptotic pancreatic β cells in obese diabetic (db/db) rats.

Technical Data

M.Wt:
307.38
Formula:
C16H18FNO2S
Solubility:
Soluble to 100 mM in DMSO and to 100 mM in ethanol
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
346692-04-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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