Dipyridamole

Biological Activity

Technical Data

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

1. CD26 expression and adenosine deaminase activity in regulatory T cells (Treg) and CD4(+) T effector cells in patients with head and neck squamous cell carcinoma.
   Mandapathil M, Szczepanski M, Harasymczuk M, Ren J, Cheng D, Jackson E, Gorelik E, Johnson J, Lang S, Whiteside T
   Oncoimmunology, 2012;1(5):659-669.
2. High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death.
   Fox JT, Sakamuru S, Huang R
   Proc. Natl. Acad. Sci. U.S.A., 2012;109(14):5423-8.
3. Cloning and characterization of a novel human phosphodiesterase that hydrolyzes both cAMP and cGMP (PDE10A).
   Fujishige et al.
   J.Biol.Chem., 1999;274:18438
4. Pharmacological analysis of the activity of the adenosine uptake inhibitor, dipyridamole, on the sinoatrial and atrioventricular nodes of the guinea-pig.
   Meester et al.
   Br.J.Pharmacol., 1998;124:729
5. Cloning and characterization of a cAMP-specific cyclic nucleotide phosphodiesterase.
   Soderling et al.
   Proc.Natl.Acad.Sci.U.S.A., 1998;95:8991
6. Synthesis, flow cytometric evaluation, and identification of highly potent dipyrid. analogues as equilibrative nucleoside transporter 1 inhibitors.
   Lin et al.
   J.Med.Chem., 2007;50:3906

Product Datasheets