DJ-V 159
Chemical Name: N1,N3-Bis(4-cyano-3-(trifluoromethyl)phenyl)isophthalamide
Purity: ≥98%
Biological Activity
DJ-V 159 is a GPRC6A agonist. Activates ERK and stimulates cAMP production in GPRC6A expressing HEK-293 cells. Stimulates insulin secretion from mouse β-cells in vitro. Reduces blood glucose levels in mice in vivo.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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Computationally identified novel agonists for GPRC6A.
Pi et al.
PLoS One, 2018;13:e0195980
Product Datasheets
Citation for DJ-V 159
The citations listed below are publications that use Tocris products. Selected citations for DJ-V 159 include:
1 Citation: Showing 1 - 1
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Substance P aggravates ligature-induced periodontitis in mice.
Authors: Sheng Et al.
Front Immunol 2023;14:1099017
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