DOPE
Chemical Name: (9Z)-1,1'-[(1R)-1-[[[(2-Aminoethoxy)hydroxyphosphinyl]oxy]methyl]-1,2-ethanediyl] 9-octadecenoic acid ester
Purity: ≥95%
Biological Activity
DOPE is a liposome/lipoplex transfection reagent. Enhances liposome and lipoplex transfection efficiency in combination with DA, DOTAP or DC-cholesterol (Cat. No. 7176).Please note: exact ratio for use and transfection efficiency is dependent on cell line used.
Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
-
The role of the helper lipid dioleoylphosphatidylethanolamine (DOPE) for DNA transfection cooperating with a cationic lipid bearing ethylenediamine.
Mochizuki et al.
Biochim.Biophys.Acta., 2013;1828:412 -
DOTAP/DOPE ratio and cell type determine transfection efficiency with DOTAP-liposomes.
Kim et al.
Biochim.Biophys.Acta., 2015;1848:1996
Product Datasheets
Reconstitution Calculator
Molarity Calculator
FAQs
No product specific FAQs exist for this product, however you may
View all Small Molecule FAQsReviews for DOPE
There are currently no reviews for this product. Be the first to review DOPE and earn rewards!
Have you used DOPE?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image