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DOTAP

Catalog #: 7179 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
7179/50
DOTAP | CAS No. 132172-61-3 | Lipid Nanoparticles
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Description: Cationic agent for liposome and LNP formation
Alternative Names: 1,2-dioleoyl-3-trimethylammoniumpropane

Chemical Name: N,N,N-Trimethyl-2,3-bis(oleoyloxy)propan-1-aminium chloride

Purity: ≥95%

Product Details
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Biological Activity Technical Data Product Datasheets Calculators

Biological Activity

DOTAP is a cationic agent used in liposome formation. Facilitates the transfection of DNA, RNA, and other molecules with negative charges into eukaryotic cells. Can be used to generate selective organ-targeting (SORT) lipid nanoparticles.

For more information on how to prepare MC3 lipid nanoparticles for RNA delivery, please see our protocol.

Technical Data

M.Wt:
698.54
Formula:
C42H80ClNO4
Solubility:
Soluble to 100 mM in ethanol and to 100 mM in chloroform
Purity:
≥95%
Storage:
Store at -20°C
CAS No:
132172-61-3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Molarity Calculator

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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

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