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DSPE-PEG 2000 Maleimide

Catalog #: 7947 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
7947/10
DSPE-PEG 2000 Maleimide | Lipid Nanoparticles
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Description: PEGylated DSPE with a maleimide reactive group

Chemical Name: 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[maleimide(polyethylene glycol-2000)]

Purity: ≥90%

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Biological Activity

DSPE-PEG 2000 Maleimide is a functionalized phospholipid-polymer conjugate. It comprises a 1,2-distearoyl-sn-glycero-PE (DSPE) covalently coupled to a linear polyethylene glycol (Mr 2000) with a maleimide-terminated end for onward chemistry. It is commonly used to synthesize antibody-coupled liposomes and lipid nanoparticles. It has been used in antibody-targeted LNP-mRNA systems to generate transient antifibrotic chimeric antigen receptor (CAR) T cells in vivo.

Technical Data

Formula:
(C2H4O)nC51H91N3O13P.NH4 or Na
Solubility:
Soluble to 10 mg/ml in ethanol with gentle warming and to 10 mg/ml in chloroform
Purity:
≥90%
Storage:
Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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