Home / Angiotensin AT1 Receptor Antagonists / EXP 3174

EXP 3174

Catalog #: 5728 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
5728/10
5728/50
EXP 3174 | CAS No. 124750-92-1 | Angiotensin AT1 Receptor Antagonists
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Description: Potent and selective AT1 antagonist

Chemical Name: 2-Butyl-4-chloro-1-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-imidazole-5-carboxylic acid

Purity: ≥98%

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Biological Activity

EXP 3174 is a potent and selective noncompetitive AT1 receptor antagonist (IC50 = 37 nM). Reduces blood pressure in a rat model. Active metabolite of Losartan potassium (Cat. No. 3798).

Technical Data

M.Wt:
436.89
Formula:
C22H21ClN6O2
Solubility:
Soluble to 100 mM in DMSO and to 100 mM in ethanol
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
124750-92-1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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