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Flufenamic acid

Catalog #: 4522
3 Citations Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
4522/50
Flufenamic acid | CAS No. 530-78-9 | Calcium-activated Chloride Channel Blockers
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Description: Calcium-activated chloride channel blocker; NSAID. Also activates TRPC6

Chemical Name: 2-[[3-(Trifluoromethyl)phenyl]amino]benzoic acid

Purity: ≥99%

Product Details
Citations (3)
Reviews
Biological Activity Technical Data Background Product Datasheets Calculators

Biological Activity

Flufenamic acid is a nonsteroidal anti-inflammatory drug (NSAID). Inhibits calcium-activated chloride channels (CaCCs). Also increases currents through TRPC6 channels and inhibits currents through TRPC3 and TRPC7 channels.

Technical Data

M.Wt:
281.23
Formula:
C14H10F3NO2
Solubility:
Soluble to 100 mM in DMSO and to 100 mM in ethanol
Purity:
≥99%
Storage:
Store at RT
CAS No:
530-78-9

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

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Citations for Flufenamic acid

The citations listed below are publications that use Tocris products. Selected citations for Flufenamic acid include:

3 Citations: Showing 1 - 3

  1. Targeting the Hippo/YAP/TAZ signalling pathway: Novel opportunities for therapeutic interventions into skin cancers.
    Authors: Ute Et al.
    Exp Dermatol  2022;31:1477-1499
  2. TRPM4 Conductances in Thalamic Reticular Nucleus Neurons Generate Persistent Firing during Slow Oscillations
    Authors: O'Malley Et al.
    J Neurosci  2020;40:4813
  3. Label-free cell phenotypic profiling decodes the composition and signaling of an endogenous ATP-sensitive potassium channel.
    Authors: Sun Et al.
    Sci Rep  2014;4:4934

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