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FSEN 1

Catalog #: 7941 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
7941/10
7941/50
FSEN 1 | CAS No. 862808-01-3 | Ferroptosis Inhibitors
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Description: Induces ferroptosis; inhibits FSP1

Chemical Name: 3-(4-Bromophenyl)-6-((4-(4-methoxyphenyl)piperazin-1-yl)methyl)thiazolo[2,3-c][1,2,4]triazole

Purity: ≥98%

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Biological Activity

FSEN 1 is a ferroptosis suppressor protein 1 (FSP1) inhibitor (IC50 = 313 nM). FSEN 1 sensitizes lung cancer cells and organoids to ferroptosis (EC50 = 69 nM) through inhibition of FSP1. Inhibits FSP1 CoQ1 oxidoreductase activity (IC50 = 688 nM).

Technical Data

M.Wt:
484.42
Formula:
C22H22BrN5OS
Solubility:
Soluble to 20 mM in DMSO
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
862808-01-3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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