FTI 276
Chemical Name: N-[4-[2(R)-Amino-3-mercaptopropyl]amino-2-phenylbenzoyl]methionine trifluoroacetate salt
Purity: ≥95%
Biological Activity
Ras CAAX peptidomimetic, a selective inhibitor of farnesyltransferase (FTase) that displays > 100-fold selectivity over geranylgeranyltransferase I (GGTase I) (IC50 values are 0.5 and 50 nM respectively). Blocks growth of human lung carcinoma expressing oncogenic K-Ras in nude mice.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
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