Galanin (1-29) (rat, mouse)
Purity: ≥95%
Biological Activity
Galanin (1-29) (rat, mouse) is a non-selective galanin receptor agonist (Ki values are 0.98, 1.48 and 1.47 nM for GAL1, GAL2 and GAL3 respectively). Anticonvulsant; prevents the occurrence of full kindled seizures in rats.Technical Data
(Modification: Thr-29 = C-terminal amide)
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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Atf3 mutant mice show reduced axon regeneration and impaired regeneration-associated gene induction after peripheral nerve injury
Open Biol, 2016;6(8):. -
Regulation of kindling epileptogenesis by hippocampal galanin type 1 and type 2 receptors: the effects of subtype-selective agonists and the role of G-protein-mediated signaling.
Mazarati et al.
J.Pharmacol.Exp.Ther., 2006;318:700 -
Cloning and expression characterization of a novel galanin receptor.
Wang et al.
J.Biol.Chem., 1997;272:51 -
Galanin receptor subtypes.
Branchek et al.
TiPS., 2000;21:109
Product Datasheets
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Citations for Galanin (1-29) (rat, mouse)
The citations listed below are publications that use Tocris products. Selected citations for Galanin (1-29) (rat, mouse) include:
5 Citations: Showing 1 - 5
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Dorsal hippocampal galanin modulates anxiety-like behaviours in rats.
Authors: Funck
Brain Res 2018;1687:74
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Involvement of galanin and galanin receptor 2 in nociceptive modulation in anterior cingulatecortex of normal rats and rats with mononeuropathy.
Authors: Zhang
Sci Rep 2017;7:45930
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Involvement of galanin and galanin receptor 1 in nociceptive modulation in the central nucleus of amygdala in normal and neuropathic rats.
Authors: Li
Sci Rep 2017;7:15317
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Atf3 mutant mice show reduced axon regeneration and impaired regeneration-associated gene induction after peripheral nerve injury.
Authors: Gey Et al.
Open Biol 2016;6
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Galanin-induced decreases in nucleus accumbens/striatum excitatory postsynaptic potentials and mor. conditioned place preference require both galanin receptor 1 and galanin receptor 2.
Authors: Einstein Et al.
Eur J Neurosci 2013;37:1541
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