GP 1a

Catalog # Availability Size / Price Qty
2764/10
2764/50

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GP 1a | CAS No. 511532-96-0 | Cannabinoid R2 / CB2 Inverse Agonists
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Description: CB2 receptor inverse agonist

Chemical Name: N-(Piperidin-1-yl)-1-(2,4-dichlorophenyl)-1,4-dihydro-6-methylindeno[1,2-c]pyrazole-3-carboxamide

Purity: ≥99%

Product Details
Citations (6)
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Reviews

Biological Activity

GP 1a is a CB2 receptor inverse agonist (pEC50 = 7.1), shown in cAMP, GTPγS and β-arrestin recruitment assays. Demonstrates approximately 30-fold selectivity for CB2 receptors over CB1 receptors. Increases P-ERK1/2 expression in HL-60 cells in vitro.

Technical Data

M.Wt:
441.35
Formula:
C23H22Cl2N4O
Solubility:
Soluble to 100 mM in DMSO and to 100 mM in ethanol
Purity:
≥99%
Storage:
Store at RT
CAS No:
511532-96-0

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Citations for GP 1a

The citations listed below are publications that use Tocris products. Selected citations for GP 1a include:

6 Citations: Showing 1 - 6

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