GSK 2033

Key Product Details

Product Description

GSK 2033 is a potent LXR antagonist (pIC₅₀ = 7.5). Enhances T-cell proliferation and blocks T 0901317-antiproliferative activity on T-cells. Cell permeable.

Product Specifications for GSK 2033

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for GSK 2033

The following data is based on the product molecular weight 591.66.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.2 mM	8.45 mL	42.25 mL	84.51 mL
1 mM	1.69 mL	8.45 mL	16.90 mL
2 mM	0.85 mL	4.23 mL	8.45 mL
10 mM	0.17 mL	0.85 mL	1.69 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 33 publications citing the usage of this product.

• Solt LXR-mediated inhibition of CD4+ T helper cells. PLoS ONE 2012 PMID: 23029557
• Zuercher Discovery of tertiary sulfonamides as potent liver X receptor antagonists. J.Med.Chem. 2010 PMID: 20345102

Product Documents for GSK 2033