Guanabenz acetate
Chemical Name: [(2,6-Dichlorobenzylidene)amino]guanidine acetate
Purity: ≥98%
Biological Activity
Guanabenz acetate is a α2-adrenergic agonist and IGRS (imidazoline I2 binding site) selective ligand.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death.
Fox JT, Sakamuru S, Huang R
Proc. Natl. Acad. Sci. U.S.A., 2012;109(14):5423-8. -
Pharmaceutically controlled designer circuit for the treatment of the metabolic syndrome.
Proc Natl Acad Sci U S A, 2013;110(1):141-6. -
Modeling the Mutational and Phenotypic Landscapes of Pelizaeus-Merzbacher Disease with Human iPSC-Derived Oligodendrocytes.
Nevin Z, Factor D, Karl R, Douvaras P, Laukka J, Windrem M, Goldman S, Fossati V, Hobson G, Tesar P
Am J Hum Genet, 0;100(4):617-634. -
Guanabenz. A review of its pharmacodynamic properties and therapeutic efficacy in hypertension.
Holmes et al.
Drugs, 1983;26:212 -
Are there multiple imidazoline binding sites?
Michel and Insel
Trends Pharmacol.Sci., 1989;10:342 -
Renal effects of infusion of rilmenidine and guan. in conscious dogs: contribution of peripheral and central nervous system α2-adrenoceptors.
Evans and Anderson
Br.J.Pharmacol., 1995;116:1557
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Citations for Guanabenz acetate
The citations listed below are publications that use Tocris products. Selected citations for Guanabenz acetate include:
5 Citations: Showing 1 - 5
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Modeling the Mutational and Phenotypic Landscapes of Pelizaeus-Merzbacher Disease with Human iPSC-Derived Oligodendrocytes.
Authors: Nevin Et al.
Am J Hum Genet 2017;100:617
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Chondroprotective effects of Salubrinal in a mouse model of osteoarthritis.
Authors: Hamamura Et al.
Proc Natl Acad Sci U S A 2015;4:84
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Distinctive subcellular inhibition of cytokine-induced SRC by salubrinal and fluid flow.
Authors: Wan Et al.
PLoS One 2014;9:e105699
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Pharmaceutically controlled designer circuit for the treatment of the metabolic syndrome.
Authors: Ye Et al.
J Korean Med Sci 2013;110:141
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Noradrenergic inputs mediate state dependence of auditory responses in the avian song system.
Authors: Cardin and Schmidt
Bone Joint Res 2004;24:7745
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