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HaXS8

Catalog #: 4991 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
4991/2
HaXS8 | CAS No. 2080306-25-6 | Protein Dimerizers
1 Image
Description: Chemical dimerizer

Chemical Name: N-[[4-[[(2-Amino-9-H-purin-6-yl)oxy]methyl]phenyl]methyl]-2-[4-[(18-chloro-3,6,9,12-tetraoxaoctadec-1yl)oxy]-2,3,5,6-tetrafluorophenoxy]acetamide

Purity: ≥90%

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Biological Activity

HaXS8 is a chemical dimerizer that promotes covalent and irreversible HaloTag® and SNAP-tag® substrate dimerization. Cell permeable.

HaloTag is a trademark of Promega Corporation, and SNAP-tag is a trademark of New England BioLabs, Inc.

Technical Data

M.Wt:
787.2
Formula:
C35H43ClF4N6O8
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥90%
Storage:
Store at -20°C
CAS No:
2080306-25-6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Cell-permeant and photocleavable chemical inducer of dimerization.
    Zimmermann et al.
    Angew Chem.Int.Ed.Engl., 2014;53:4717
  2. Chemical development of intracellular protein heterodimerizers.
    Erhart et al.
    Chem.Biol., 2013;20:549

Product Datasheets

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