Human Aminopeptidase LRAP/ERAP2 Biotinylated Antibody

Catalog #: BAF3830 Datasheet / COA / SDS

Catalog #	Availability	Size / Price	Qty
BAF3830

Product Details

Supplemental Products

Reviews

Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human Aminopeptidase LRAP/ERAP2 Biotinylated Antibody Summary

Species Reactivity

Human

Specificity

Detects human Aminopeptidase LRAP/ERAP2 in Western blots.

Source

Polyclonal Goat IgG

Purification

Antigen Affinity-purified

Immunogen

Mouse myeloma cell line NS0-derived recombinant human Aminopeptidase LRAP/ERAP2
Ala56-Thr960
Accession # Q6P179

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.

Label

Biotin

Applications

Recommended Concentration

Sample

Western Blot

0.1 µg/mL

Recombinant Human Aminopeptidase LRAP/ERAP2 (Catalog # 3830-ZN)

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Reconstitution

Reconstitute at 0.2 mg/mL in sterile PBS.

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: Aminopeptidase LRAP/ERAP2

Leukocyte-derived arginine aminopeptidase (LRAP) and endoplasmic reticulum-aminopeptidase 2 (ERAP2) are the two names given to the protein encoded by the LRAP gene (1, 2). Induced by interferon-gamma, LRAP is able to trim various MHC class I antigenic peptide precursors. It belongs to the oxytocinase subfamily of M1 aminopeptidases, which also includes aminopeptidases PILS/ARTS1/ERAP1 and LNPEP/PLAP (1, 3). In addition to antigen presentation, the members of this subfamily are also important in maintenance of pregnancy, memory retention, and blood pressure regulation (3).

Long Name

Leukocyte-derived Arginine Aminopeptidase

Entrez Gene IDs

64167 (Human)

Alternate Names

Aminopeptidase LRAP; EC 3.4.11; EC 3.4.11.3; endoplasmic reticulum aminopeptidase 2; ERAP2; FLJ23633; FLJ23701; FLJ23807; Leukocyte-derived arginine aminopeptidase; LRAPL-RAPEC 3.4.11.-