Human BMP-7 Biotinylated Antibody

Catalog #: BAM354
1 Citation Datasheet / COA / SDS

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BAM354

All BMP-7 Antibodies

Product Details

Citations (1)

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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human BMP-7 Biotinylated Antibody Summary

Species Reactivity

Human

Specificity

Detects human BMP-7 in ELISAs. In ELISAs, this antibody shows less than 0.125% cross-reactivity with recombinant human (rh) BMP‑2, rhBMP‑3, rhBMP‑4, rhBMP‑5, rhBMP‑6, rhBMP‑8, rhTGF‑ beta 1, rhTGF‑ beta 2, or rhTGF‑ beta 3.

Source

Monoclonal Mouse IgG₁ Clone # 164324

Purification

Protein A or G purified from hybridoma culture supernatant

Immunogen

Chinese hamster ovary cell line CHO-derived recombinant human BMP‑7
Arg292-His431
Accession # P18075

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.

Label

Biotin

Applications

Recommended Concentration

Sample

Human BMP-7 Sandwich Immunoassay

Recommended Concentration

Reagent

ELISA Detection (Matched Antibody Pair)

0.5-2.0 µg/mL

Use in combination with:

Capture Reagent: Human BMP‑7 Antibody (Catalog # MAB3542)

Standard: Recombinant Human BMP-7 Protein (Catalog # 354-BP)

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Reconstitution

Reconstitute at 0.5 mg/mL in sterile PBS.

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: BMP-7

BMP-7, also known as Osteogenic Protein 1 (OP-1), is one of at least 15 structurally and functionally related BMPs, which are members of the TGF-beta superfamily. BMPs regulate cartilage and bone formation, embryogenesis and morphogenesis of various tissues and organs, and growth, differentiation, chemotaxis, and apoptosis of various cell types. Biologically active BMP-7 is a disulfide-linked homodimer. Cellular responses to BMP-7 have been shown to be mediated by the formation of hetero-oligomeric complexes of type I and type II serine/threonine kinase receptors.

Long Name

Bone Morphogenetic Protein 7

Entrez Gene IDs

655 (Human); 12162 (Mouse); 85272 (Rat)

Alternate Names

BMP7; BMP-7; bone morphogenetic protein 7; Eptotermin alfa; OP-1; OP-1OP1; Osteogenic protein 1

Product Datasheets

Product Datasheet

COA

SDS

Related Research Areas

Citation for Human BMP-7 Biotinylated Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

1 Citation: Showing 1 - 1

Biomaterial-Mediated Protein Expression Induced by Peptide-mRNA Nanoparticles Embedded in Lyophilized Collagen Scaffolds
Authors: R Oude Egber, HM Zegelaar, N El Boujnou, EMM Versteeg, WF Daamen, R Brock
Pharmaceutics, 2022-08-02;14(8):.
Species: Mouse
Sample Types: Complex Sample Type
Applications: ELISA Detection