Human C-Reactive Protein/CRP Quantikine ELISA Kit

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Human C-Reactive Protein/CRP ELISA Standard Curve
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Human C-Reactive Protein/CRP Quantikine ELISA Kit Summary

Assay Type
Solid Phase Sandwich ELISA
Format
96-well strip plate
Assay Length
4.5 hours
Sample Type & Volume Required Per Well
Cell Culture Supernates (50 uL), Serum (50 uL), EDTA Plasma (50 uL), Heparin Plasma (50 uL)
Sensitivity
0.022 ng/mL
Assay Range
0.8 - 50 ng/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma)
Specificity
Natural and recombinant human CRP
Cross-reactivity
< 0.5% cross-reactivity observed with available related molecules.< 50% cross-species reactivity observed with species tested.
Interference
No significant interference observed with available related molecules.

Sample Values

Serum/Plasma - Samples from apparently healthy volunteers were evaluated for the presence of human CRP in this assay. No medical histories were available for the donors used in this study.

Sample TypeMean (ng/mL)Range (ng/mL)Standard Deviation (ng/mL)
Serum (n=35)17691091214
EDTA plasma (n=35)1547104-41851082
Heparin plasma (n=35)1624108-45231138
Note: Four additional serum, EDTA plasma, and heparin plasma patient sample sets were tested and resulted in substantially higher values. The values for each donor averaged 7364 ng/mL, 12,363 ng/mL, 16,064 ng/mL, and 43,036 ng/mL.

Cell Culture Supernates - Human peripheral blood cells (1 x 106 cells/mL) were cultured in DMEM supplemented with 5% fetal bovine serum, 50 μM beta -mercaptoethanol, 2 mM L-glutamine, 100 U/mL penicillin, and 100 μg/mL streptomycin sulfate. Cells were cultured unstimulated or stimulated with 10 μg/mL PHA. Aliquots of the cell culture supernate were removed and assayed for levels of human CRP. No detectable levels were observed. 

Product Summary

The Quantikine Human CRP Immunoassay is a 4.5 hour solid-phase ELISA designed to measure human CRP in cell culture supernates, serum, and plasma. It contains NS0-expressed recombinant human CRP and has been shown to accurately quantitate the recombinant factor. Results obtained using natural human CRP showed linear curves that were parallel to the standard curves obtained using the Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for naturally occurring human CRP.

Precision

Intra-Assay Precision (Precision within an assay) Three samples of known concentration were tested on one plate to assess intra-assay precision
Inter-Assay Precision (Precision between assays) Three samples of known concentration were tested in separate assays to assess inter-assay precision

Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma

Intra-Assay Precision Inter-Assay Precision
Sample 1 2 3 1 2 3
n 20 20 20 40 40 40
Mean (pg/mL) 4.79 8.66 18.9 4.84 8.66 17.5
Standard Deviation 0.21 0.33 1.57 0.29 0.61 1.15
CV% 4.4 3.8 8.3 6 7 6.6

Recovery

The recovery of CRP spiked to levels throughout the range of the assay in cell culture media was evaluated.

Sample Type Average % Recovery Range %
Cell Culture Media (n=4) 100 92-110

Linearity

To assess the linearity of the assay, samples containing and/or spiked with high concentrations of CRP were serially diluted with the Calibrator Diluent to produce samples with values within the dynamic range of the assay.
Human C-Reactive Protein/CRP ELISA Linearity

Scientific Data

Human C-Reactive Protein/CRP ELISA Standard Curve

Product Datasheets

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Preparation and Storage

Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Background: C-Reactive Protein/CRP

C-Reactive Protein (CRP), also known as Pentraxin 1, is a non-glycosylated protein in the Pentraxin family that also includes Pentraxin 2/SAP and Pentraxin 3/TSG-14. CRP functions as a sensor and activator of the innate immune response (1). In humans, it is a major acute-phase protein; its circulating concentration is dramatically elevated at the onset of inflammation (2). In mice, however, serum CRP levels increase only slightly during inflammation, and the analogous acute phase role is filled by Pentraxin 2 (3). CRP assembles non-covalently into a 110-120 kDa cyclical pentamer (4). Mature human CRP shares 71% and 64% amino acid (aa) sequence identity with mouse and rat CRP, respectively (5). 

CRP binds and opsonizes apoptotic cells (6-8) as well as bacteria such as S. pneumoniae (9, 10). It subsequently enhances the phagocytosis of these opsonized cells (6, 8-10). CRP additionally binds several proteins in the complement cascade including C1q, C4BP, and Factor H (8, 11-13). It enhances activation of the classical complement pathway and the deposition of C3b (9). In later stages of the response, CRP inhibits complement-mediated cell lysis through its binding to C4BP and Factor H (8, 12). These interactions induce the upregulation of complement inhibitory proteins CD46, CD59, and CD55/DAF and inhibit assembly of the membrane attack complex (MAC) (8, 14). 
CRP binds to Fc gamma RI, Fc gamma RIIA, and Fc gamma RIIB on macrophages and dendritic cells (15-17), and Fc receptors are required for the phagocytosis of CRP-opsonized target cells (6, 10, 18). CRP binding to Fc gamma RI induces Src activation which subsequently triggers the inhibitory Fc gamma RIIb and dampens the inflammatory response (15, 19). CRP additionally promotes dendritic cell maturation and humoral immunity (10). In cardiovascular disease, CRP binds to oxidized LDL, exacerbates tissue damage in coronary artery infarction, and inhibits the repair of injured vascular endothelium (7, 19, 20). 

Entrez Gene IDs:
1401 (Human); 12944 (Mouse); 25419 (Rat)
Alternate Names:
C-Reactive Protein; C-reactive protein, pentraxin-related; CRP; MGC88244; pentraxin 1; PTX1MGC149895
&#9888; WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.

Assay Procedure

Refer to the product for complete assay procedure.

Bring all reagents and samples to room temperature before use. It is recommended that all samples, standards, and controls be assayed in duplicate.
  1.   Prepare all reagents, standard dilutions, and samples as directed in the product insert.
  2.   Remove excess microplate strips from the plate frame, return them to the foil pouch containing the desiccant pack, and reseal.

  3. 100 µL Assay Diluent
  4.   Add 100 µL of Assay Diluent to each well.

  5. 50 µL Standard, Control, or Sample
  6.   Add 50 µL of Standard, control, or sample to each well. Cover with a plate sealer, and incubate at room temperature for 2 hours.
  7.   Aspirate each well and wash, repeating the process 3 times for a total of 4 washes.

  8. 200 µL Conjugate
  9.   Add 200 µL of Conjugate to each well. Cover with a new plate sealer, and incubate at room temperature for 2 hours.
  10.   Aspirate and wash 4 times.

  11. 200 µL Substrate Solution
  12.   Add 200 µL Substrate Solution to each well. Incubate at room temperature for 30 minutes. PROTECT FROM LIGHT.

  13. 50 µL Stop Solution
  14.   Add 50 µL of Stop Solution to each well. Read at 450 nm within 30 minutes. Set wavelength correction to 540 nm or 570 nm.

Citations for Human C-Reactive Protein/CRP Quantikine ELISA Kit

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

143 Citations: Showing 1 - 10
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  1. A (poly)phenol-rich diet reduces serum and faecal calprotectin in older adults with increased intestinal permeability: the MaPLE randomised controlled trial
    Authors: Marino, M;Del Bo', C;Martini, D;Perna, S;Porrini, M;Cherubini, A;Gargari, G;Meroño, T;Hidalgo-Liberona, N;Andres-Lacueva, C;Kroon, PA;Guglielmetti, S;Riso, P;
    BMC geriatrics
    Species: Human
    Sample Types: Serum
  2. Fasting-mimicking diet causes hepatic and blood markers changes indicating reduced biological age and disease risk
    Authors: Brandhorst, S;Levine, ME;Wei, M;Shelehchi, M;Morgan, TE;Nayak, KS;Dorff, T;Hong, K;Crimmins, EM;Cohen, P;Longo, VD;
    Nature communications
    Species: Human
    Sample Types: Plasma
  3. Social isolation, loneliness, and inflammation: A multi-cohort investigation in early and mid-adulthood
    Authors: Matthews, T;Rasmussen, LJH;Ambler, A;Danese, A;Eugen-Olsen, J;Fancourt, D;Fisher, HL;Iversen, KK;Schultz, M;Sugden, K;Williams, B;Caspi, A;Moffitt, TE;
    Brain, behavior, and immunity
    Species: Human
    Sample Types: Plasma
  4. Endoplasmic Reticulum Stress Promotes the Expression of TNF-? in THP-1 Cells by Mechanisms Involving ROS/CHOP/HIF-1? and MAPK/NF-?B Pathways
    Authors: Akhter, N;Wilson, A;Arefanian, H;Thomas, R;Kochumon, S;Al-Rashed, F;Abu-Farha, M;Al-Madhoun, A;Al-Mulla, F;Ahmad, R;Sindhu, S;
    International journal of molecular sciences
    Species: Human
    Sample Types: Plasma
  5. Antiretroviral treatment is less effective at reducing gut microbiome-associated inflammation and T cell activation in people living with HIV in rural versus urban Zimbabwe
    Authors: Lazzaro, A;Colorado, ASB;Neff, CP;Nusbacher, N;Boyd, K;Fiorillo, S;Martin, C;Siebert, J;Campbell, T;Borok, M;Palmer, B;Lozupone, C;
    Research square
    Species: Human
    Sample Types: Plasma
  6. Effect of Modernized Collaborative Care for Depression on Depressive Symptoms and Cardiovascular Disease Risk Biomarkers: eIMPACT Randomized Controlled Trial
    Authors: Stewart, JC;Patel, JS;Polanka, BM;Gao, S;Nurnberger, JI;MacDonald, KL;Gupta, SK;Considine, RV;Kovacs, RJ;Vrany, EA;Berntson, J;Hsueh, L;Shell, AL;Rollman, BL;Callahan, CM;
    Brain, behavior, and immunity
    Species: Human
    Sample Types: Plasma
  7. Adipose tissue specific CCL18 associates with cardiometabolic diseases in non-obese individuals implicating CD4+ T cells
    Authors: N Subramania, K Hofwimmer, B Tavira, L Massier, DP Andersson, P Arner, J Laurenciki
    Cardiovascular Diabetology, 2023-04-12;22(1):84.
    Species: Human
    Sample Types: Cell Culture Supernates
  8. Affective neural circuits and inflammatory markers linked to depression and anxiety symptoms in patients with comorbid obesity
    Authors: H Hallihan, P Tsai, N Lv, L Xiao, B Peñalver B, Y Wu, GN Pandey, LM Williams, OA Ajilore, J Ma
    Journal of psychiatric research, 2023-02-03;160(0):9-18.
    Species: Human
    Sample Types: Plasma
  9. Relationships among Inflammatory Biomarkers and Self-Reported Treatment-Related Symptoms in Patients Treated with Chemotherapy for Gynecologic Cancer: A Controlled Comparison
    Authors: Hoogland, A;Small, B;Oswald, L;Bryant, C;Rodriguez, Y;Gonzalez, B;Li, X;Janelsins, M;Bulls, H;James, B;Arboleda, B;Colon-Echevarria, C;Townsend, M;Tworoger, S;Rodriguez, P;Bower, J;Apte, S;Wenham, R;Jim, H;
    Cancers
    Species: Human
    Sample Types: Serum, Plasma
  10. Plasma complement C3 and C3a are increased in major depressive disorder independent of childhood trauma
    Authors: X Luo, Z Fang, L Lin, H Xu, Q Huang, H Zhang
    BMC Psychiatry, 2022-11-29;22(1):741.
    Species: Human
    Sample Types: Plasma
  11. Novel hit of DPP-4Is as promising antihyperglycemic agents with dual antioxidant/anti-inflammatory effects for type 2 diabetes with/without COVID-19
    Authors: S Mahgoub, SS Fatahala, AI Sayed, HB Atya, MF El-Shehry, H Afifi, SM Awad, RHA El-Hameed, H Taha
    Bioorganic chemistry, 2022-08-10;128(0):106092.
    Species: Human
    Sample Types: Cell Culture Supernates
  12. Bromocriptine-QR Therapy Reduces Sympathetic Tone and Ameliorates a Pro-Oxidative/Pro-Inflammatory Phenotype in Peripheral Blood Mononuclear Cells and Plasma of Type 2 Diabetes Subjects
    Authors: AH Cincotta, E Cersosimo, M Alatrach, M Ezrokhi, C Agyin, J Adams, R Chilton, C Triplitt, B Chamarthi, N Cominos, RA DeFronzo
    International Journal of Molecular Sciences, 2022-08-09;23(16):.
    Species: Human
    Sample Types: Plasma
  13. Inflammatory and metabolic markers in relation to outcome of in vitro fertilization in a cohort of predominantly overweight and obese women
    Authors: H Svensson, S Einarsson, D Olausson, L Kluge, C Bergh, S Edén, M Lönn, A Thurin-Kje
    Scientific Reports, 2022-08-03;12(1):13331.
    Species: Human
    Sample Types: Serum
  14. Peri-event plasma PCSK9 and hsCRP after an acute myocardial infarction correlate with early deterioration of left ventricular ejection fraction: a cohort study
    Authors: LS Silva-Berm, A Vargas-Vil, CA Sánchez-Va, AC Palacio, AF Buitrago, CO Mendivil
    Oncogene, 2022-07-21;21(1):61.
    Species: Human
    Sample Types: Plasma
  15. A comprehensive approach to predicting weight gain and therapy response in psychopharmacologically treated major depressed patients: A cohort study protocol
    Authors: MS Simon, BB Barton, C Glocker, R Musil
    PLoS ONE, 2022-07-21;17(7):e0271793.
    Species: Human
    Sample Types: Plasma
  16. Improving Dietary Intake of Essential Nutrients Can Ameliorate Inflammation in Patients with Diabetic Foot Ulcers
    Authors: R Basiri, M Spicer, C Levenson, T Ledermann, N Akhavan, B Arjmandi
    Nutrients, 2022-06-09;14(12):.
    Species: Human
    Sample Types: Plasma
  17. Associations of maternal iron deficiency with malaria infection in a cohort of pregnant Papua New Guinean women
    Authors: HW Unger, A Bleicher, M Ome-Kaius, EH Aitken, SJ Rogerson
    Malaria Journal, 2022-05-26;21(1):153.
    Species: Human
    Sample Types: Plasma
  18. Acrylamide exposure increases cardiovascular risk of general adult population probably by inducing oxidative stress, inflammation, and TGF-beta1: A prospective cohort study
    Authors: B Wang, X Wang, L Yu, W Liu, J Song, L Fan, M Zhou, M Yang, J Ma, M Cheng, W Qiu, R Liang, D Wang, Y Guo, W Chen
    Environment international, 2022-04-25;164(0):107261.
    Species: Human
    Sample Types: Plasma
  19. Relationship of Diet to Gut Microbiota and Inflammatory Biomarkers in People with HIV
    Authors: M Manzano, A Talavera-R, E Moreno, N Madrid, MJ Gosalbes, R Ron, F Dronda, JA Pérez-Moli, VF Lanza, J Díaz, S Moreno, B Navia, S Serrano-Vi
    Nutrients, 2022-03-14;14(6):.
    Species: Human
    Sample Types: Plasma
  20. LncRNA MALAT1 functions as a biomarker of no-reflow phenomenon in ST-segment elevation myocardial infarction patients receiving primary percutaneous coronary intervention
    Authors: X Yang, R Dai, Z Qin, R Cai, Y Xu, Q Su
    Scientific Reports, 2022-02-28;12(1):3294.
    Species: Human
    Sample Types: Plasma
  21. Adherence to and changes in mental and physiological health during an 8-week yoga intervention: A pilot study
    Authors: B Forseth, M Polfuss, M Brondino, SD Hunter, MW Lawlor, MJ Beatka, MJ Prom, J Eells, JA Lyons
    Journal of bodywork and movement therapies, 2022-01-19;30(0):203-209.
    Species: Human
    Sample Types: Serum
  22. Longitudinal associations between adolescents' individualised risk for depression and inflammation in a UK cohort study
    Authors: RM Latham, C Kieling, L Arseneault, BA Kohrt, TE Moffitt, LJH Rasmussen, TB Rocha, V Mondelli, HL Fisher
    Brain, Behavior, and Immunity, 2022-01-03;101(0):78-83.
    Species: Human
    Sample Types: Plasma
  23. Effects of resistance exercise and whey protein supplementation on skeletal muscle strength, mass, physical function, and hormonal and inflammatory biomarkers in healthy active older men: A randomised, double-blind, placebo-controlled trial
    Authors: C Griffen, M Duncan, J Hattersley, MO Weickert, A Dallaway, D Renshaw
    Experimental gerontology, 2021-12-09;0(0):111651.
    Species: Human
    Sample Types: Plasma
  24. Expression of Circulating MicroRNAs and Myokines and Interactions with Serum Osteopontin in Type 2 Diabetic Patients with Moderate and Poor Glycemic Control: A Biochemical and Molecular Study
    Authors: HA Al-Rawaf, AH Alghadir, SA Gabr
    BioMed Research International, 2021-12-07;2021(0):7453000.
    Species: Human
    Sample Types: Serum
  25. Plasma BDNF and Cytokines Correlated with Protein Biomarkers for Bipolar II Disorder
    Authors: SY Lee, TY Wang, RB Lu, LJ Wang, CH Chang, YC Chiang, CC Pan, KW Tsai
    Journal of personalized medicine, 2021-12-02;11(12):.
    Species: Human
    Sample Types: Plasma
  26. Gut-Derived Endotoxin and Telomere Length Attrition in Adults with and without Type 2 Diabetes
    Authors: NM Al-Daghri, S Abdi, S Sabico, AM Alnaami, KA Wani, MGA Ansari, MNK Khattak, N Khan, G Tripathi, GP Chrousos, PG McTernan
    Biomolecules, 2021-11-14;11(11):.
    Species: Human
    Sample Types: Serum
  27. Oral vitamin C restores endothelial function during acute inflammation in young and older adults
    Authors: EC Lefferts, BA Hibner, WK Lefferts, NS Lima, T Baynard, JM Haus, AD Lane-Cordo, SA Phillips, B Fernhall
    Physiological Reports, 2021-11-01;9(21):e15104.
    Species: Human
    Sample Types: Serum
  28. Relationship between the Plasma Proteome and Changes in Inflammatory Markers after Bariatric Surgery
    Authors: HA Fachim, Z Iqbal, JM Gibson, I Baricevic-, AE Campbell, B Geary, AA Syed, A Whetton, H Soran, RP Donn, AH Heald
    Cells, 2021-10-19;10(10):.
    Species: Human
    Sample Types: Plasma
  29. Socioeconomic Status and Inflammation in Women with Early-stage Breast Cancer: Mediation by Body Mass Index
    Authors: YK Pageot, AL Stanton, PA Ganz, MR Irwin, SW Cole, CM Crespi, EC Breen, KR Kuhlman, JE Bower
    Brain, Behavior, and Immunity, 2021-10-18;99(0):307-316.
    Species: Human
    Sample Types: Plasma
  30. The relationship between markers of antenatal iron stores and birth outcomes differs by malaria prevention regimen-a prospective cohort study
    Authors: HW Unger, V Laurita Lo, A Bleicher, M Ome-Kaius, S Karl, JA Simpson, A Karahalios, EH Aitken, SJ Rogerson
    Bmc Medicine, 2021-10-05;19(1):236.
    Species: Human
    Sample Types: blood
  31. Innate lymphoid cell dysfunction during long-term suppressive antiretroviral therapy in an African cohort
    Authors: R Nabatanzi, L Bayigga, S Cose, G Canderan, S Rowland Jo, M Joloba, D Nakanjako
    BMC immunology, 2021-08-26;22(1):59.
    Species: Human
    Sample Types: Serum
  32. Alteration of immune profiles is associated with pulmonary function and symptoms in patients with chronic obstructive pulmonary disease
    Authors: S Li, S Zhao, Z Wu, F Wang, W Li
    Molecular Medicine Reports, 2021-08-26;24(5):.
    Species: Human
    Sample Types: Plasma
  33. Associations between childhood victimization, inflammatory biomarkers and psychotic phenomena in adolescence: a longitudinal cohort study
    Authors: A Trotta, L Arseneault, A Danese, V Mondelli, LJH Rasmussen, HL Fisher
    Brain, Behavior, and Immunity, 2021-08-11;0(0):.
    Species: Human
    Sample Types: Plasma
  34. Cytokine profiles in children with acute intussusception in South Africa
    Authors: TK Bessey, UD Parashar, JE Tate, South Afri, SA Madhi, B Jiang, MJ Groome
    Cytokine, 2021-07-17;146(0):155639.
    Species: Human
    Sample Types: Serum
  35. Thermoregulation is not impaired in breast cancer survivors during moderate-intensity exercise performed in warm and hot environments
    Authors: RL Relf, BJ Lee, G Eichhorn, MS Flint, L Beale, N Maxwell
    Physiological Reports, 2021-07-01;9(14):e14968.
    Species: Human
    Sample Types: Plasma
  36. Interleukin-8 and lower severity of depression in females, but not males, with treatment-resistant depression
    Authors: JL Kruse, R Olmstead, G Hellemann, EC Breen, SJ Tye, JO Brooks, B Wade, E Congdon, R Espinoza, KL Narr, MR Irwin
    Journal of psychiatric research, 2021-06-09;140(0):350-356.
    Species: Human
    Sample Types: Plasma
  37. Associations Between C-Reactive Protein Levels, Exercise Addiction, and Athlete Burnout in Endurance Athletes
    Authors: L Becker, A Dupke, N Rohleder
    Frontiers in psychology, 2021-06-04;12(0):615715.
    Species: Human
    Sample Types: Serum
  38. Bacterial DNAemia is associated with serum zonulin levels in older subjects
    Authors: G Gargari, G Mantegazza, V Taverniti, C Del Bo', S Bernardi, C Andres-Lac, R González-D, PA Kroon, MS Winterbone, A Cherubini, P Riso, S Guglielmet
    Scientific Reports, 2021-05-26;11(1):11054.
    Species: Human
    Sample Types: Serum
  39. Tumor-Associated Macrophage Promotes the Survival of Cancer Cells upon Docetaxel Chemotherapy via the CSF1/CSF1R-CXCL12/CXCR4 Axis in Castration-Resistant Prostate Cancer
    Authors: W Guan, F Li, Z Zhao, Z Zhang, J Hu, Y Zhang
    Genes, 2021-05-19;12(5):.
    Species: Mouse
    Sample Types: Cell Lysates
  40. Cardiovascular Risk Is Increased in Miner's Chronic Intermittent Hypobaric Hypoxia Exposure From 0 to 2,500 m?
    Authors: A Pedreros-L, R Calderón-J, D Moraga, FA Moraga
    Frontiers in Physiology, 2021-03-26;12(0):647976.
    Species: Human
    Sample Types: Serum
  41. Influence of serum inflammatory cytokines on cytochrome P450 drug metabolising activity during breast cancer chemotherapy: a patient feasibility study
    Authors: RLI Crake, MR Strother, E Phillips, MP Doogue, M Zhang, CMA Frampton, BA Robinson, MJ Currie
    Scientific Reports, 2021-03-11;11(1):5648.
    Species: Human
    Sample Types: Serum
  42. Vulnerability to inflammation-related depressive symptoms: Moderation by stress in women with breast cancer
    Authors: AW Manigault, KR Kuhlman, MR Irwin, SW Cole, PA Ganz, CM Crespi, JE Bower
    Brain, Behavior, and Immunity, 2021-03-09;0(0):.
    Species: Human
    Sample Types: Plasma
  43. Association between yoga, physiologic and psychologic health: A cross sectional study
    Authors: B Forseth, M Polfuss, M Brondino, MW Lawlor, MJ Beatka, MJ Prom, J Eells, JA Lyons
    Complementary therapies in clinical practice, 2021-03-04;43(0):101350.
    Species: Human
    Sample Types: Serum
  44. Inflammaging markers characteristic of advanced age show similar levels with frailty and dependency
    Authors: A Alberro, A Iribarren-, M Sáenz-Cues, A Matheu, I Vergara, D Otaegui
    Scientific Reports, 2021-02-23;11(1):4358.
    Species: Human
    Sample Types: Plasma, Serum
  45. Fecal microbiota transplantation in HIV: A pilot placebo-controlled study
    Authors: S Serrano-Vi, A Talavera-R, MJ Gosalbes, N Madrid, JA Pérez-Moli, RJ Elliott, B Navia, VF Lanza, A Vallejo, M Osman, F Dronda, S Budree, J Zamora, C Gutiérrez, M Manzano, MJ Vivancos, R Ron, J Martínez-S, S Herrera, U Ansa, A Moya, S Moreno
    Nature Communications, 2021-02-18;12(1):1139.
    Species: Human
    Sample Types: Plasma
  46. Prebiotic effect on mood in obese patients is determined by the initial gut microbiota composition: A randomized, controlled trial
    Authors: Q Leyrolle, R Cserjesi, M D G H Muld, G Zamariola, S Hiel, MA Gianfrance, D Portheault, C Amadieu, LB Bindels, S Leclercq, J Rodriguez, AM Neyrinck, PD Cani, N Lanthier, P Trefois, J Bindelle, N Paquot, M Cnop, JP Thissen, O Klein, O Luminet, NM Delzenne
    Brain, Behavior, and Immunity, 2021-01-28;94(0):289-298.
    Species: Human
    Sample Types: Plasma
  47. Inflammatory biomarker relationships with helper T cell GPR15 expression and cannabis and tobacco smoking
    Authors: AM Andersen, MK Lei, SRH Beach, RA Philibert
    Journal of psychosomatic research, 2020-12-06;141(0):110326.
    Species: Human
    Sample Types: Serum
  48. Assessment of a dried blood spot C-reactive protein method to identify disease flares in rheumatoid arthritis patients
    Authors: LG D'Cruz, KG McEleney, C Cochrane, KBC Tan, P Shukla, PV Gardiner, D Small, SD Zhang, DS Gibson
    Scientific Reports, 2020-12-03;10(1):21089.
    Species: Human
    Sample Types: Plasma
  49. Moderate aerobic training modulates cytokines and cortisol profiles in older adults with cognitive abilities
    Authors: AH Alghadir, SA Gabr, M Al-Momani, F Al-Momani
    Cytokine, 2020-11-25;0(0):155373.
    Species: Human
    Sample Types: Serum
  50. APOE-&epsilon4-related differences in left thalamic microstructure in cognitively healthy adults
    Authors: JP Mole, F Fasano, J Evans, R Sims, E Kidd, JP Aggleton, C Metzler-Ba
    Sci Rep, 2020-11-13;10(1):19787.
    Species: Human
    Sample Types: Plasma
  51. Paracoccidioides brasiliensis downmodulates &alpha3 integrin levels in human lung epithelial cells in a TLR2-dependent manner
    Authors: BCSC de Barros, BR Almeida, E Suzuki
    Sci Rep, 2020-11-10;10(1):19483.
    Species: Human
    Sample Types: Cell Culture Supernates
  52. The effect of smoking on chronic inflammation, immune function and blood cell composition
    Authors: I Elisia, V Lam, B Cho, M Hay, MY Li, M Yeung, L Bu, W Jia, N Norton, S Lam, G Krystal
    Sci Rep, 2020-11-10;10(1):19480.
    Species: Human
    Sample Types: Plasma
  53. Supplementing Glycine and N-acetylcysteine (GlyNAC) in Aging HIV Patients Improves Oxidative Stress, Mitochondrial Dysfunction, Inflammation, Endothelial Dysfunction, Insulin Resistance, Genotoxicity, Strength, and Cognition: Results of an Open-Label Clinical Trial
    Authors: P Kumar, C Liu, JW Suliburk, CG Minard, R Muthupilla, S Chacko, JW Hsu, F Jahoor, RV Sekhar
    Biomedicines, 2020-09-30;8(10):.
    Species: Human
    Sample Types: Plasma
  54. Re-evaluation of serum leptin and adiponectin concentrations normalized by body fat mass in patients with rheumatoid arthritis
    Authors: K Chihara, N Hattori, N Ichikawa, T Matsuda, T Saito
    Sci Rep, 2020-09-28;10(1):15932.
    Species: Human
    Sample Types: Serum
  55. Clinical value of selected markers of angiogenesis, inflammation, insulin resistance and obesity in type 1 endometrial cancer
    Authors: KM Terlikowsk, B Dobrzycka, R Terlikowsk, A Sienkiewic, M Kinalski, SJ Terlikowsk
    BMC Cancer, 2020-09-25;20(1):921.
    Species: Human
    Sample Types: Serum
  56. Elevated acute phase proteins reflect peripheral inflammation and disease severity in patients with amyotrophic lateral sclerosis
    Authors: DR Beers, W Zhao, DW Neal, JR Thonhoff, AD Thome, A Faridar, S Wen, J Wang, SH Appel
    Scientific Reports, 2020-09-17;10(1):15295.
    Species: Human
    Sample Types: Serum
  57. Cognitive functional therapy (CFT) compared with core training exercise (CTE) in patients with failed back surgery syndrome (FBSS): A study protocol for a randomized controlled trial
    Authors: L Avila, ML Neves, AR Abreu, CR Fiuza, L Fukusawa, N Meziat-Fil, AR Soares San
    Journal of bodywork and movement therapies, 2020-09-14;26(0):428-434.
    Species: Human
    Sample Types: Serum
  58. Micronutrient status of Palestinian school children following salt and flour fortification: a cross-sectional study
    Authors: S Massad, M Gebre-Medh, O Dary, M Abdalla, S Holleran, W Karmally, P Bordelois, U Khammash, RJ Deckelbaum
    BMC Nutr, 2020-08-26;6(0):38.
    Species: Human
    Sample Types: Whole Blood
  59. Pro-inflammatory markers and fatigue in patients with depression: A case-control study
    Authors: B Pedraz-Pet, E Neumann, G Sammer
    Sci Rep, 2020-06-11;10(1):9494.
    Species: Human
    Sample Types: Plasma
  60. Obesity prolongs the hospital stay in patients affected by COVID-19, and may impact on SARS-COV-2 shedding
    Authors: D Moriconi, S Masi, E Rebelos, A Virdis, ML Manca, S De Marco, S Taddei, M Nannipieri
    Obes Res Clin Pract, 2020-06-04;14(3):205-209.
    Species: Human
    Sample Types: Plasma
  61. Associations between essential metals exposure and metabolic syndrome (MetS): Exploring the mediating role of systemic inflammation in a general Chinese population
    Authors: J Ma, Y Zhou, D Wang, Y Guo, B Wang, Y Xu, W Chen
    Environ Int, 2020-05-28;140(0):105802.
    Species: Human
    Sample Types: Plasma
  62. Permissive microbiome characterizes human subjects with a neurovascular disease cavernous angioma
    Authors: SP Polster, A Sharma, C Tanes, AT Tang, P Mericko, Y Cao, J Carrión-Pe, R Girard, J Koskimäki, D Zhang, A Stadnik, SG Romanos, SB Lyne, R Shenkar, K Yan, C Lee, A Akers, L Morrison, M Robinson, A Zafar, K Bittinger, H Kim, JA Gilbert, ML Kahn, L Shen, IA Awad
    Nat Commun, 2020-05-27;11(1):2659.
    Species: Human
    Sample Types: Plasma
  63. Effect of a polyphenol-rich dietary pattern on intestinal permeability and gut and blood microbiomics in older subjects: study protocol of the MaPLE randomised controlled trial
    Authors: S Guglielmet, S Bernardi, C Del Bo', A Cherubini, M Porrini, G Gargari, N Hidalgo-Li, R Gonzalez-D, G Peron, R Zamora-Ros, MS Winterbone, B Kirkup, PA Kroon, C Andres-Lac, P Riso
    BMC Geriatr, 2020-02-26;20(1):77.
    Species: Human
    Sample Types: Serum
  64. Physical performances show conflicting associations in aged manual workers
    Authors: KL Norheim, A Samani, JH Bønløkke, Ø Omland, P Madeleine
    Sci Rep, 2020-02-10;10(1):2254.
    Species: Human
    Sample Types: Plasma
  65. Exploratory examination of inflammation state, immune response and blood cell composition in a human obese cohort to identify potential markers predicting cancer risk
    Authors: I Elisia, V Lam, B Cho, M Hay, MY Li, J Kapeluto, T Elliott, D Harris, L Bu, W Jia, H Leung, W Mohn, G Krystal
    PLoS ONE, 2020-02-06;15(2):e0228633.
    Species: Human
    Sample Types: Plasma
  66. Advanced Age Is Associated with Iron Dyshomeostasis and Mitochondrial DNA Damage in Human Skeletal Muscle
    Authors: A Picca, RT Mankowski, G Kamenov, SD Anton, TM Manini, TW Buford, SK Saini, R Calvani, F Landi, R Bernabei, E Marzetti, C Leeuwenbur
    Cells, 2019-11-27;8(12):.
    Species: Human
    Sample Types: Plasma
  67. Assessing Validity of Self-Reported Dietary Intake within a Mediterranean Diet Cluster Randomized Controlled Trial among US Firefighters
    Authors: M Sotos-Prie, C Christophi, A Black, JD Furtado, Y Song, P Magiatis, A Papakonsta, E Melliou, S Moffatt, SN Kales
    Nutrients, 2019-09-19;11(9):.
    Species: Human
    Sample Types: Serum
  68. Pretransplant Levels of C-Reactive Protein,�Soluble TNF Receptor-1, and�CD38+HLADR+ CD8 T Cells Predict Risk of Allograft Rejection in HIV+ Kidney Transplant Recipients
    Authors: JF Camargo, S Pallikkuth, I Moroz, Y Natori, ML Alcaide, A Rodriguez, G Guerra, GW Burke, S Pahwa
    Kidney Int Rep, 2019-08-19;4(12):1705-1716.
    Species: Human
    Sample Types: Plasma
  69. Adverse childhood experiences (ACEs) and cardiovascular development from childhood to early adulthood: study protocol of the Niagara Longitudinal Heart Study
    Authors: TJ Wade, DD O'Leary, KS Dempster, AJ MacNeil, DS Molnar, J McGrath, J Cairney
    BMJ Open, 2019-07-16;9(7):e030339.
    Species: Human
    Sample Types: Serum
  70. Application of non-invasive detection of peripheral vascular dysfunction in ovarian hyperstimulation syndrome (OHSS): A pilot study of clinical relevance
    Authors: TH Chin, CP Lin, SD Chang, HS Wang, HY Huang, YK Soong, HM Wu, PH Chu
    Taiwan J Obstet Gynecol, 2019-05-01;58(3):354-358.
    Species: Human
    Sample Types: Serum
  71. Low-Grade Inflammation Is Associated with Apathy Indirectly via Deep White Matter Lesions in Community-Dwelling Older Adults: The Sefuri Study
    Authors: H Yao, Y Mizoguchi, A Monji, Y Yakushiji, Y Takashima, A Uchino, T Yuzuriha, M Hashimoto
    Int J Mol Sci, 2019-04-17;20(8):.
    Species: Human
    Sample Types: Serum
  72. The effect of resistance exercise upon age-related systemic and local skeletal muscle inflammation
    Authors: AK Ziegler, SM Jensen, P Schjerling, AL Mackey, JL Andersen, M Kjaer
    Exp. Gerontol., 2019-03-21;121(0):19-32.
    Species: Human
    Sample Types: Serum
  73. Impact of a 12-month Inflammation Management Intervention on the Dietary Inflammatory Index, inflammation, and lipids
    Authors: GM Turner-McG, MD Wirth, N Shivappa, CG Dunn, A Crimarco, TG Hurley, DS West, JR Hussey, JR Hébert
    Clin Nutr ESPEN, 2019-03-01;30(0):42-51.
    Species: Human
    Sample Types: Whole Blood
  74. Hypoallergenic and anti-inflammatory feeds in children with complicated severe acute malnutrition: an open randomised controlled 3-arm intervention trial in Malawi
    Authors: RH Bartels, E Chimwezi, V Watson, L Pei, I Potani, B Allubha, K Chidzalo, D Wang, Q Dube, M Mallewa, A Allen, RHJ Bandsma, WP Voskuijl, SJ Allen
    Sci Rep, 2019-02-19;9(1):2304.
    Species: Human
    Sample Types: Plasma
  75. Sulphadoxine-pyrimethamine plus azithromycin may improve birth outcomes through impacts on inflammation and placental angiogenesis independent of malarial infection
    Authors: HW Unger, AP Hansa, C Buffet, W Hasang, A Teo, L Randall, M Ome-Kaius, S Karl, AA Anuan, JG Beeson, I Mueller, SJ Stock, SJ Rogerson
    Sci Rep, 2019-02-19;9(1):2260.
    Species: Human
    Sample Types: Plasma
  76. Sex-specific effects of central adiposity and inflammatory markers on limbic microstructure
    Authors: C Metzler-Ba, JP Mole, E Leonaviciu, R Sims, EJ Kidd, B Ertefai, A Kelso-Mitc, F Gidney, F Fasano, J Evans, DK Jones, RJ Baddeley
    Neuroimage, 2019-02-05;189(0):793-803.
    Species: Human
    Sample Types: Plasma
  77. Effect of TCF7L2 polymorphism on pancreatic hormones after exenatide in type 2 diabetes
    Authors: MC Ferreira, MER da Silva, RT Fukui, M do Carmo A, S Azhar, RF Dos Santos
    Diabetol Metab Syndr, 2019-01-25;11(0):10.
    Species: Human
    Sample Types: Serum
  78. Beyond the HPA-axis: Exploring maternal prenatal influences on birth outcomes and stress reactivity
    Authors: S Nazzari, P Fearon, F Rice, N Dottori, F Ciceri, M Molteni, A Frigerio
    Psychoneuroendocrinology, 2018-11-14;101(0):253-262.
    Species: Human
    Sample Types: Serum
  79. Combination of Plasma Biomarkers and Clinical Data for the Detection of Myocardial Fibrosis or Aggravation of Heart Failure Symptoms in Heart Failure with Preserved Ejection Fraction Patients
    Authors: CK Wu, MM Su, YF Wu, JJ Hwang, LY Lin
    J Clin Med, 2018-11-08;7(11):.
    Species: Human
    Sample Types: Plasma
  80. Serum Metrnl is associated with the presence and severity of coronary artery disease
    Authors: ZX Liu, HH Ji, MP Yao, L Wang, Y Wang, P Zhou, Y Liu, XF Zheng, HW He, LS Wang, W Gao, X Lu
    J. Cell. Mol. Med., 2018-11-05;0(0):.
    Species: Human
    Sample Types: Serum
  81. Aggression, impulsivity and inflammatory markers as risk factors for suicidal behavior
    Authors: W Coryell, H Wilcox, SJ Evans, GN Pandey, L Jones-Bran, F Dickerson, R Yolken
    J Psychiatr Res, 2018-09-11;106(0):38-42.
    Species: Human
    Sample Types: Plasma
  82. Interplay between acute phase response and coagulation/fibrinolysis in chronic spontaneous urticaria
    Authors: R Grzanka, A Damasiewic, A Kasperska-
    Allergy Asthma Clin Immunol, 2018-07-18;14(0):27.
    Species: Human
    Sample Types: Serum
  83. Increased serum iron in preeclamptic women is likely due to low hepcidin levels
    Authors: F Brunacci, VS Rocha, E De Carli, BP Espósito, R Ruano, C Colli
    Nutr Res, 2018-03-21;0(0):.
    Species: Human
    Sample Types: Serum
  84. Improvement of cognitive functions in response to a regular Nordic walking training in elderly women - A change dependent on the training experience
    Authors: A Gmi?t, J Jaworska, K Micielska, J Kortas, K Prusik, K Prusik, M Lipowski, A Radulska, N Szupryczy?, J Antosiewic, E Ziemann
    Exp. Gerontol., 2018-02-09;104(0):105-112.
    Species: Human
    Sample Types: Serum
    Applications: ELISA Capture
  85. Plasma Levels of Myonectin But Not Myostatin or Fibroblast-Derived Growth Factor 21 Are Associated with Insulin Resistance in Adult Humans without Diabetes Mellitus
    Authors: FJK Toloza, JO Mantilla-R, MC Pérez-Mato, ML Ricardo-Si, MC Morales-Al, JA Pinzón-Cor, M Pérez-Mayo, ML Arévalo-Ga, G Tolosa-Gon, CO Mendivil
    Front Endocrinol (Lausanne), 2018-01-31;9(0):5.
    Species: Human
    Sample Types: Plasma
  86. The DiPEP (Diagnosis of PE in Pregnancy) biomarker study: An observational cohort study augmented with additional cases to determine the diagnostic utility of biomarkers for suspected venous thromboembolism during pregnancy and puerperium
    Authors: BJ Hunt, K Parmar, K Horspool, N Shephard, C Nelson-Pie, S Goodacre
    Br. J. Haematol., 2018-01-23;0(0):.
    Species: Human
    Sample Types: Serum
  87. An in vivo assessment of the cholesterol-lowering efficacy of Lactobacillus plantarum ECGC 13110402 in normal to mildly hypercholesterolaemic adults
    Authors: A Costabile, I Buttarazzi, S Kolida, S Quercia, J Baldini, JR Swann, P Brigidi, GR Gibson
    PLoS ONE, 2017-12-11;12(12):e0187964.
    Species: Human
    Sample Types: Serum
  88. Potential serum biomarkers and metabonomic profiling of serum in ischemic stroke patients using UPLC/Q-TOF MS/MS
    Authors: H Sun, J Zhao, D Zhong, G Li
    PLoS ONE, 2017-12-11;12(12):e0189009.
    Species: Human
    Sample Types: Serum
  89. Plasma irisin is elevated in type 2 diabetes and is associated with increased E-selectin levels
    Authors: KS Rana, C Pararasa, I Afzal, DA Nagel, EJ Hill, CJ Bailey, HR Griffiths, I Kyrou, HS Randeva, S Bellary, JE Brown
    Cardiovasc Diabetol, 2017-11-09;16(1):147.
    Species: Human
    Sample Types: Plasma
  90. Reevaluation of immune activation in the era of cART and an aging HIV-infected population
    Authors: LR de Armas, S Pallikkuth, V George, S Rinaldi, R Pahwa, KL Arheart, S Pahwa
    JCI Insight, 2017-10-19;2(20):.
    Species: Human
    Sample Types: Plasma
  91. C-reactive protein improves the ability to detect cardiometabolic risk in mild-to-moderate obstructive sleep apnea
    Authors: J Gaines, L Kong, M Li, J Fernandez-, EO Bixler, M Basta, AN Vgontzas
    Physiol Rep, 2017-09-01;5(18):.
    Species: Human
    Sample Types: Plasma
  92. Preliminary study of hypoxia-related cardiovascular mediator-markers in patients with end-stage renal disease with and without diabetes and the effects of haemodialysis
    Authors: A Treweeke, J Hall, S Lambie, SJ Leslie, IL Megson, SM MacRury
    PLoS ONE, 2017-05-23;12(5):e0178171.
    Species: Human
    Sample Types: Plasma
  93. Serological biomarkers detect active joint destruction and inflammation in patients with haemophilic arthropathy
    Authors: B Hua, EHN Olsen, S Sun, CN Gudme, L Wang, B Vandahl, K Roepstorff, M Kjelgaard-, BB Sørensen, Y Zhao, MA Karsdal, T Manon-Jens
    Haemophilia, 2017-04-24;0(0):.
    Species: Human
    Sample Types: Tissue Homogenates
  94. Lipoprotein apheresis in the treatment of dyslipidaemia - the Czech Republic experience
    Authors: V Bláha, M Bláha, M Lánská, D Solichová, L Kujovská K, E Havel, P Vyroubal, Z Zadák, P Žák, L Sobotka
    Physiol Res, 2017-04-05;66(0):S91-S100.
    Species: Human
    Sample Types: Serum
  95. Rapid and Low-Cost CRP Measurement by Integrating a Paper-Based Microfluidic Immunoassay with Smartphone (CRP-Chip)
    Authors: M Dong, J Wu, Z Ma, H Peretz-Sor, M Zhang, P Komenda, N Tangri, Y Liu, C Rigatto, F Lin
    Sensors (Basel), 2017-03-26;17(4):.
    Species: Human
    Sample Types: Serum
  96. Link between plasminogen activator inhibitor-1 and cardiovascular risk in chronic hepatitis C after viral clearance
    Authors: ML Chang, YS Lin, LH Pao, HC Huang, CT Chiu
    Sci Rep, 2017-02-13;7(0):42503.
    Species: Human
    Sample Types: Serum
  97. Immunogenic FEAT protein circulates in the bloodstream of cancer patients
    J Transl Med, 2016-09-22;14(1):275.
    Species: Human
    Sample Types: Plasma
  98. Vitamin D supplementation reduces insulin resistance in Japanese adults: a secondary analysis of a double-blind, randomized, placebo-controlled trial
    Authors: Xiaomin Sun
    Nutr Res, 2016-07-27;36(10):1121-1129.
    Species: Human
    Sample Types: Plasma
  99. P2X7 Receptor Inhibition Improves CD34 T-Cell Differentiation in HIV-Infected Immunological Nonresponders on c-ART
    Authors: I Menkova-Ga, H Hocini, E Foucat, P Tisserand, L Bourdery, C Delaugerre, C Benne, Y Lévy, JD Lelièvre
    PLoS Pathog, 2016-04-15;12(4):e1005571.
    Species: Human
    Sample Types: Plasma
  100. Effects of nateglinide and rosiglitazone on pancreatic alpha- and beta-cells, GLP-1 secretion and inflammatory markers in patients with type 2 diabetes: randomized crossover clinical study.
    Authors: Tostes G, Cunha M, Fukui R, Correia M, Rocha D, Dos Santos R, da Silva M
    Diabetol Metab Syndr, 2016-01-04;8(0):1.
    Species: Human
    Sample Types: Serum
  101. Serum levels of inflammatory markers in depressed elderly patients with diabetes and mild cognitive impairment.
    Authors: Gorska-Ciebiada M, Saryusz-Wolska M, Borkowska A, Ciebiada M, Loba J
    PLoS ONE, 2015-03-20;10(3):e0120433.
    Species: Human
    Sample Types: Serum
  102. Number of sons contributes to ageing-associated inflammation.
    Authors: Marttila S, Nevalainen T, Kananen L, Jylhava J, Jylha M, Hervonen A, Ilonen J, Hurme M
    Sci Rep, 2015-02-27;5(0):8631.
    Species: Human
    Sample Types: Plasma
  103. C-reactive protein (CRP), interferon gamma-inducible protein 10 (IP-10), and lipopolysaccharide (LPS) are associated with risk of tuberculosis after initiation of antiretroviral therapy in resource-limited settings.
    Authors: Tenforde M, Gupte N, Dowdy D, Asmuth D, Balagopal A, Pollard R, Sugandhavesa P, Lama J, Pillay S, Cardoso S, Pawar J, Santos B, Riviere C, Mwelase N, Kanyama C, Kumwenda J, Hakim J, Kumarasamy N, Bollinger R, Semba R, Campbell T, Gupta A
    PLoS ONE, 2015-02-26;10(2):e0117424.
    Species: Human
    Sample Types: Plasma
  104. Prognostic value of a quantitative analysis of lipoarabinomannan in urine from patients with HIV-associated tuberculosis.
    Authors: Kerkhoff A, Wood R, Vogt M, Lawn S
    2014-07-30;0(0):.
    Species: Human
    Sample Types: Serum
  105. Effects of pitavastatin versus atorvastatin on the peripheral endothelial progenitor cells and vascular endothelial growth factor in high-risk patients: a pilot prospective, double-blind, randomized study.
    Authors: Lin L, Huang C, Chen J, Wu T, Leu H, Huang P, Chang T, Lin S, Chen J
    Cardiovasc Diabetol, 2014-07-16;13(0):111.
    Species: Human
    Sample Types: Serum
  106. The expression of cytokines and chemokines in the blood of patients with severe weight loss from anorexia nervosa: an exploratory study.
    Authors: Pisetsky D, Trace S, Brownley K, Hamer R, Zucker N, Roux-Lombard P, Dayer J, Bulik C
    Cytokine, 2014-06-14;69(1):110-5.
    Species: Human
    Sample Types: Cell Culture Supernates
  107. Plasma sCD14 as a biomarker to predict pulmonary exacerbations in cystic fibrosis.
    Authors: Quon B, Ngan D, Wilcox P, Man S, Sin D
    PLoS ONE, 2014-02-20;9(2):e89341.
    Species: Human
    Sample Types: Plasma
  108. Plasma level of cyclophilin A is increased in patients with type 2 diabetes mellitus and suggests presence of vascular disease.
    Authors: Ramachandran S, Venugopal A, Kutty V, A V, G D, Chitrasree V, Mullassari A, Pratapchandran N, Santosh K, Pillai M, Kartha C
    Cardiovasc Diabetol, 2014-02-07;13(0):38.
    Species: Human
    Sample Types: Plasma
  109. HIV-associated tuberculosis: relationship between disease severity and the sensitivity of new sputum-based and urine-based diagnostic assays.
    Authors: Lawn S, Kerkhoff A, Vogt M, Wood R
    BMC Med, 2013-10-29;11(0):231.
    Species: Human
    Sample Types: Serum
  110. Characterization of the role of distinct plasma cell-free DNA species in age-associated inflammation and frailty.
    Authors: Jylhava J, Nevalainen T, Marttila S, Jylha M, Hervonen A, Hurme M
    Aging Cell, 2013-04-01;12(3):388-97.
    Species: Human
    Sample Types: Plasma
  111. Predictive value of liver enzymes and inflammatory biomarkers for the severity of liver fibrosis stage in HIV/HCV co-infected patients.
    Authors: Charpentier C, Champenois K, Gervais A, Landman R, Joly V, Le Gac S, Larrouy L, Damond F, Brun-Vezinet F, Descamps D, Yazdanpanah Y
    PLoS ONE, 2013-03-19;8(3):e59205.
    Species: Human
    Sample Types: Plasma
  112. Influence of interleukin-4 gene polymorphisms and interleukin-4 serum level on susceptibility and severity of rheumatoid arthritis in Egyptian population.
    Authors: Hussein Y, El-Shal A, Rezk N, Abdel Galil S, Alzahrani S
    Cytokine, 2013-02-06;61(3):849-55.
    Species: Human
    Sample Types: Serum
  113. Prolonged neutrophil dysfunction after Plasmodium falciparum malaria is related to hemolysis and heme oxygenase-1 induction.
    Authors: Cunnington, Aubrey J, Njie, Madi, Correa, Simon, Takem, Ebako N, Riley, Eleanor, Walther, Michael
    J Immunol, 2012-10-24;189(11):5336-46.
    Species: Human
    Sample Types: Plasma
  114. Shared monocyte subset phenotypes in HIV-1 infection and in uninfected subjects with acute coronary syndrome.
    Authors: Funderburg, Nicholas, Zidar, David A, Shive, Carey, Lioi, Anthony, Mudd, Joseph, Musselwhite, Laura W, Simon, Daniel I, Costa, Marco A, Rodriguez, Benigno, Sieg, Scott F, Lederman, Michael
    Blood, 2012-10-11;120(23):4599-608.
    Species: Human
    Sample Types: Plasma
  115. Elevated serum adipocyte fatty acid-binding protein concentrations are independently associated with renal dysfunction in patients with stable angina pectoris.
    Authors: Iwamoto M, Miyoshi T, Doi M
    Cardiovasc Diabetol, 2012-03-21;11(0):26.
    Species: Human
    Sample Types: Serum
  116. Plasma desmoplakin I biomarker of vascular recurrence after ischemic stroke.
    Authors: Lopez-Farre AJ, Zamorano-Leon JJ, Segura A, Mateos-Caceres PJ, Modrego J, Rodriguez-Sierra P, Calatrava L, Tamargo J, Macaya C
    J. Neurochem., 2012-03-13;121(2):314-25.
    Species: Human
    Sample Types: Plasma
  117. The relationship of systemic inflammation to prior hospitalization in adult patients with cystic fibrosis.
    Authors: Ngan D, Wilcox P, Aldaabil M, Li Y, Leipsic J, Sin D, Man S
    BMC Pulm Med, 2012-02-14;12(0):3.
    Species: Human
    Sample Types: Plasma
  118. Cortisol responses to mental stress and the progression of coronary artery calcification in healthy men and women.
    Authors: Hamer M, Endrighi R, Venuraju SM, Lahiri A, Steptoe A
    PLoS ONE, 2012-02-06;7(2):e31356.
    Species: Human
    Sample Types: Serum
  119. Validation and quality control of ELISAs for the use with human saliva samples.
    Authors: Jaedicke KM, Taylor JJ, Preshaw PM
    J. Immunol. Methods, 2012-01-28;377(1):62-5.
    Species: Human
    Sample Types: Saliva
  120. Comparison of acute versus convalescent stage high-sensitivity C-Reactive protein level in predicting clinical outcome after acute ischemic stroke and impact of erythropoietin.
    Authors: Yeh KH, Tsai TH, Chai HT, Leu S, Chung SY, Chua S, Chen YL, Lin HS, Yuen CM, Yip HK
    J Transl Med, 2012-01-05;10(0):6.
    Species: Human
    Sample Types: Serum
  121. Increased prevalence of albuminuria in HIV-infected adults with diabetes.
    Authors: Kim PS, Woods C, Dutcher L, Georgoff P, Rosenberg A, Mican JA, Kopp JB, Smith MA, Hadigan C
    PLoS ONE, 2011-09-13;6(9):e24610.
    Species: Human
    Sample Types: Serum
  122. Inflammation associated with obesity: relationship with blood and bone marrow endothelial cells.
    Authors: McGuire TR, Brusnahan SK, Bilek LD, Jackson JD, Kessinger MA, Berger AM, Garvin KL, O'Kane BJ, Tuljapurkar SR, Sharp JG
    Obesity (Silver Spring), 2011-09-08;19(11):2130-6.
    Species: Human
    Sample Types: Plasma
  123. Time-course of changes in inflammatory response after whole-body cryotherapy multi exposures following severe exercise.
    Authors: Pournot H, Bieuzen F, Louis J, Fillard JR, Barbiche E, Hausswirth C
    PLoS ONE, 2011-07-28;6(7):e22748.
    Species: Human
    Sample Types: Plasma
  124. C-reactive protein promotes diabetic kidney disease in a mouse model of type 1 diabetes.
    Authors: Liu F, Chen HY, Huang XR, Chung AC, Zhou L, Fu P, Szalai AJ, Lan HY
    Diabetologia, 2011-07-09;54(10):2713-23.
    Species: Human
    Sample Types: Cell Culture Supernates
  125. C-reactive protein promotes acute renal inflammation and fibrosis in unilateral ureteral obstructive nephropathy in mice.
    Authors: Li ZI, Chung AC, Zhou L, Huang XR, Liu F, Fu P, Fan JM, Szalai AJ, Lan HY
    Lab. Invest., 2011-03-07;91(6):837-51.
    Species: Transgenic Mouse
    Sample Types: Serum
  126. Association of angiopoietin-2, C-reactive protein and markers of obesity and insulin resistance with survival outcome in colorectal cancer.
    Authors: Volkova E, Willis JA, Wells JE, Robinson BA, Dachs GU, Currie MJ
    Br. J. Cancer, 2010-11-16;104(1):51-9.
    Species: Human
    Sample Types: Serum
  127. Differential adaptation of human gut microbiota to bariatric surgery-induced weight loss: links with metabolic and low-grade inflammation markers.
    Authors: Furet JP, Kong LC, Tap J, Poitou C, Basdevant A, Bouillot JL, Mariat D, Corthier G, Dore J, Henegar C, Rizkalla S, Clement K
    Diabetes, 2010-09-28;59(12):3049-57.
    Species: Human
    Sample Types: Plasma
  128. Folic acid treatment normalizes NOS-dependence of vascular tone in the metabolic syndrome.
    Authors: Schneider MP, Schlaich MP, Harazny JM, Raff U, Ritt M, Ott C, Schmieder RE
    Obesity (Silver Spring), 2010-09-23;19(5):960-7.
    Species: Human
    Sample Types: Serum
  129. Tauroursodeoxycholic Acid may improve liver and muscle but not adipose tissue insulin sensitivity in obese men and women.
    Authors: Kars M, Yang L, Gregor MF, Mohammed BS, Pietka TA, Finck BN, Patterson BW, Horton JD, Mittendorfer B, Hotamisligil GS, Klein S
    Diabetes, 2010-06-03;59(8):1899-905.
    Species: Human
    Sample Types: Plasma
  130. Exenatide affects circulating cardiovascular risk biomarkers independently of changes in body composition.
    Authors: Bunck MC, Diamant M, Eliasson B, Corner A, Shaginian RM, Heine RJ, Taskinen MR, Yki-Jarvinen H, Smith U
    Diabetes Care, 2010-04-27;33(8):1734-7.
    Species: Human
    Sample Types: Serum
  131. Improvements in coronary heart disease risk indicators by alternate-day fasting involve adipose tissue modulations.
    Authors: Bhutani S, Klempel MC, Berger RA, Varady KA
    Obesity (Silver Spring), 2010-03-18;18(11):2152-9.
    Species: Human
    Sample Types: Plasma
  132. Persistent cognitive depressive symptoms are associated with coronary artery calcification.
    Authors: Hamer M, Kivimaki M, Lahiri A
    Atherosclerosis, 2010-02-04;210(1):209-13.
    Species: Human
    Sample Types: Serum
  133. Effect of intensive lifestyle changes on endothelial function and on inflammatory markers of atherosclerosis.
    Authors: Dod HS, Bhardwaj R, Sajja V, Weidner G, Hobbs GR, Konat GW, Manivannan S, Gharib W, Warden BE, Nanda NC, Beto RJ, Ornish D, Jain AC
    Am. J. Cardiol., 2010-02-01;105(3):362-7.
    Species: Human
    Sample Types: Serum
  134. Reduction of elevated plasma osteopontin levels with resection of non-small-cell lung cancer.
    Authors: Blasberg JD, Pass HI, Goparaju CM, Flores RM, Lee S, Donington JS
    J. Clin. Oncol., 2010-01-19;28(6):936-41.
    Species: Human
    Sample Types: Plasma
  135. Salivary cortisol responses to mental stress are associated with coronary artery calcification in healthy men and women.
    Authors: Hamer M, O'Donnell K, Lahiri A, Steptoe A
    Eur. Heart J., 2009-09-10;31(4):424-9.
    Species: Human
    Sample Types: Serum
  136. Validity of multiplex-based assays for cytokine measurements in serum and plasma from "non-diseased" subjects: comparison with ELISA.
    Authors: Dossus L, Becker S, Achaintre D, Kaaks R, Rinaldi S
    J. Immunol. Methods, 2009-09-10;350(1):125-32.
    Species: Human
    Sample Types: Serum
  137. Predictors of maintaining cognitive function in older adults: the Health ABC study.
    Authors: Yaffe K, Fiocco AJ, Lindquist K, Vittinghoff E, Simonsick EM, Newman AB, Satterfield S, Rosano C, Rubin SM, Ayonayon HN, Harris TB
    Neurology, 2009-06-09;72(23):2029-35.
    Species: Human
    Sample Types: Plasma
  138. Prospective study of physical fitness, adiposity, and inflammatory markers in healthy middle-aged men and women.
    Authors: Hamer M, Steptoe A
    Am. J. Clin. Nutr., 2008-12-03;89(1):85-9.
    Species: Human
    Sample Types: Plasma
  139. Endothelial progenitor cell levels in obese men with the metabolic syndrome and the effect of simvastatin monotherapy vs. simvastatin/ezetimibe combination therapy.
    Authors: Westerweel PE, Visseren FL, Hajer GR, Olijhoek JK, Hoefer IE, de Bree P, Rafii S, Doevendans PA, Verhaar MC
    Eur. Heart J., 2008-09-28;29(22):2808-17.
    Species: Human
    Sample Types: Serum
  140. Effects of atorvastatin added to inhaled corticosteroids on lung function and sputum cell counts in atopic asthma.
    Authors: Hothersall EJ, Chaudhuri R, McSharry C, Donnelly I, Lafferty J, McMahon AD, Weir CJ, Meiklejohn J, Sattar N, McInnes I, Wood S, Thomson NC
    Thorax, 2008-08-29;63(12):1070-5.
    Species: Human
    Sample Types: Serum
  141. C-reactive protein (CRP) induces chemokine secretion via CD11b/ICAM-1 interaction in human adherent monocytes.
    Authors: Montecucco F, Steffens S, Burger F, Pelli G, Monaco C, Mach F
    J. Leukoc. Biol., 2008-06-30;84(4):1109-19.
    Species: Human
    Sample Types: Recombinant Protein
  142. Effects of rehabilitative exercise on peripheral muscle TNFalpha, IL-6, IGF-I and MyoD expression in patients with COPD.
    Authors: Vogiatzis I, Stratakos G, Simoes DC, Terzis G, Georgiadou O, Roussos C, Zakynthinos S
    Thorax, 2007-06-15;62(11):950-6.
    Species: Human
    Sample Types: Plasma
  143. Muscle atrophy and hypertrophy signaling in patients with chronic obstructive pulmonary disease.
    Authors: Doucet M, Russell AP, Leger B, Debigare R, Joanisse DR, Caron MA, LeBlanc P, Maltais F
    Am. J. Respir. Crit. Care Med., 2007-05-03;176(3):261-9.
    Species: Human
    Sample Types: Plasma

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Reviews for Human C-Reactive Protein/CRP Quantikine ELISA Kit

Average Rating: 5 (Based on 4 Reviews)

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Human C-Reactive Protein/CRP Quantikine ELISA Kit
By Anonymous on 03/22/2021
Sample Tested: EDTA Plasma

Great kit, used frequently on EDTA plasma without issue. Would recommend.


Human C-Reactive Protein/CRP Quantikine ELISA Kit
By Anonymous on 10/05/2020
Sample Tested: EDTA Plasma

Human C-Reactive Protein/CRP Quantikine ELISA Kit
By Ping Yi on 10/04/2020
Sample Tested: Serum

Human C-Reactive Protein/CRP Quantikine ELISA Kit
By Anonymous on 10/02/2017
Sample Tested: Serum and Plasma

Robust and very easy to use assay