Human Calcitonin R (NP_001733) VersaClone cDNA

Catalog #: RDC0108 Datasheet / COA / SDS

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RDC0108

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Human Calcitonin R (NP_001733) VersaClone cDNA Summary

Specifications

Shipping Conditions

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Species

Human

Product Datasheets

Product Datasheet

COA

SDS

Background: Calcitonin R

The Calcitonin Receptor (CALCR) is a glycosylated 70 kDa seven-transmembrane G protein-coupled receptor that mediates the hypocalcemic effects of the peptide hormone, calcitonin. CALCR activation inhibits osteoclast-mediated bone resorption and enhances renal calcium excretion. CALCR polymorphisms and mutations have been associated with several bone disorders. Alternate splicing of the Calcitonin Receptor results in the deletion of 16 aa in the first cytoplasmic loop or 23 aa in the first extracellular region. Human CALCR shares 70% - 72% aa sequence identity with mouse and rat CACLR.

Long Name

Calcitonin Receptor

Entrez Gene IDs

799 (Human); 12311 (Mouse); 116506 (Rat)

Alternate Names

Calcitonin R; calcitonin receptor; CalcitoninR; CALCR; CRT; CTR; CT-R; CTR1