Human CCK-AR Antibody

Catalog #: MAB2680 Datasheet / COA / SDS

Catalog #	Availability	Size / Price	Qty
MAB2680
MAB2680-SP

All CCK-AR Antibodies

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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human CCK-AR Antibody Summary

Species Reactivity

Human

Specificity

Detects human CCK‑A R. Stains human CCK-A R transfectants but not irrelevant transfectants.

Source

Monoclonal Mouse IgG_2A Clone # 377251

Purification

Protein A or G purified from hybridoma culture supernatant

Immunogen

NS0 mouse myeloma cell line transfected with human CCK‑A R
Met1-Gln428
Accession # P32238

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Label

Unconjugated

Applications

Recommended Concentration

Sample

Flow Cytometry

2.5 µg/10⁶ cells

Human CCK‑A R transfected cells

CyTOF-ready

Ready to be labeled using established conjugation methods. No BSA or other carrier proteins that could interfere with conjugation.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Reconstitution

Reconstitute at 0.5 mg/mL in sterile PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: CCK-AR

Cholecystokinin A Receptor (CCK-A R) is one of two 7TM receptors for cholecystokinin peptide hormones. This GPCR is involved in gallbladder contraction, insulin secretion, and central nervous system function. CCK-A R has been implicated in pancreatic tumorigenesis as well as the pathogenesis of eating disorders and drug addiction. Human CCK-A R shares 89% aa sequence identity with mouse and rat CCK-A R.

Long Name

Cholecystokinin Receptor, Type A

Entrez Gene IDs

886 (Human); 12425 (Mouse)

Alternate Names

CCK1R; CCK1-R; CCK-A R; CCK-A receptor; CCK-A; CCKAR; CCK-AR; CCKRA; cholecystokinin A receptor; cholecystokinin receptor type A; cholecystokinin type-A receptor; Cholecystokinin-1 receptor